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Dr Christopher Course

Dr Christopher Course

Clinical Research Fellow

School of Medicine

Email
coursecw@cardiff.ac.uk
Telephone
+44 (0)29 2074 4499
Campuses
Main Hospital Building, University Hospital of Wales, Heath Park, Cardiff, CF14 4XN

Overview

I graduated from Cardiff Univesrity Medical School in 2011 during which time I also completed an intercalated BSc in Pyschology & Medicine. Since graduation, I entered paediatric training in 2014, and I am currently on the subspeciality training programme for neonatology run by the Royal College of Paediatrics and Child Health.

At present I am taking three years away from clinical work to complete a PhD investigating the biochemical mediators of reduced lung function in school aged survivors of premature birth. This work is mainly focused on proteomic and metabolomic analysis of respiratory and urine samples taken from a large cohort of children who participated in the RHiNO (Respiratory Health Outcomes in Neonates) study. I am also a member of the team undertaking two-year follow up for infants enrolled on the AZTEC (Azithromcyin for Chronic Lung Disease of Prematurity) trial, which is examining the use of early azithromycin to prevent chronic lung disease of prematurity.

Biography

2021 - 2024: Clinical Research Fellow/PhD Student, Department of Child Health, School of Medicine, Cardiff University, UK

2019 - 2025: Neonatalogy Speciality Trainee, Health Education and Improvement Wales, UK

2014 - 2019: Paediatric Speciality Trainee, Health Education and Improvement Wales, UK

2013 - 2014: Clinical Fellow, Department of Neonatology, University Hospital of Wales, Cardiff, UK

2011 - 2013: Foundation Programme Trainee, Wales Deanery, UK

2005 - 2011: Undergraduate, School of Medicine, Cardiff, UK

Publications

2021

2020

2019

2017

Premature birth acocunts for approximately 10% of all live births and represents a substantial health interest. Infants born extremely prematurely (<28 weeks completed gestation) are at high risk for early mortality and longer term morbidity, with increased repsiratory symptoms and neurodevelopmental problems. Those infants born less premature still have an increased risk of longer term morbidity.

My area of interest relates to the early and long term respiratroy outcomes for infants born prematurely. My current research project is examining whether there is a detectable biochemical change in school age children born prematurely with reduced lung function, compared to those preterm born children with better lung function and term match controls. To undertake this I am analsying proteomic and metabolomic data taken as part of a large clinical study (RHINO: Respiratory Health Outcomes for Neonates). This work is being supervised by Professor Sailesh Kotecha, Dr Sarah Kotecha and Dr John Watkins.