Dr Pedro Luque Laguna
Research Associate
- LuqueLagunaP@cardiff.ac.uk
- Cardiff University Brain Research Imaging Centre, Maindy Road, Cardiff, CF24 4HQ
Overview
My research focuses on image analysis of magnetic resonance imaging data (MRI), with a focus on diffusion MRI of the brain. I am interested in extracting anatomical and topological information from diffusion MRI tractography that can be further applied to the analysis of MRI data and other neuroimaging modalities. My research in CUBRIC has been primarily focused on finding novel ways of using tractography to harmonize the analysis of longitudinal MRI data acquired at different sites for each time point.
Publication
2023
- MacIver, C. et al. 2023. Macro- and micro-structural Insights into primary dystonia A UK Biobank study. Journal of Neurology (10.1007/s00415-023-12086-2)
2022
- Casella, C. et al. 2022. Mutation-related magnetization-transfer, not axon density, drives white matter differences in premanifest Huntington's disease: Evidence from in vivo ultra-strong gradient MRI. Human Brain Mapping 43(11), pp. 3439-3460. (10.1002/hbm.25859)
2021
- Casella, C. et al. 2021. Mutation-related apparent myelin, not axon density, drives white matter differences in premanifest Huntington's disease: evidence from in vivo ultra-strong gradient MRI. [Online]. bioRxiv. (10.1101/2021.11.29.469517) Available at: https://doi.org/10.1101/2021.11.29.469517
- Merritt, K., Luque Laguna, P., Irfan, A. and David, A. S. 2021. Longitudinal Structural MRI Findings in Individuals at Genetic and Clinical High Risk for Psychosis: A Systematic Review. Frontiers in Psychiatry 12, article number: 620401. (10.3389/fpsyt.2021.620401)
Articles
- MacIver, C. et al. 2023. Macro- and micro-structural Insights into primary dystonia A UK Biobank study. Journal of Neurology (10.1007/s00415-023-12086-2)
- Casella, C. et al. 2022. Mutation-related magnetization-transfer, not axon density, drives white matter differences in premanifest Huntington's disease: Evidence from in vivo ultra-strong gradient MRI. Human Brain Mapping 43(11), pp. 3439-3460. (10.1002/hbm.25859)
- Merritt, K., Luque Laguna, P., Irfan, A. and David, A. S. 2021. Longitudinal Structural MRI Findings in Individuals at Genetic and Clinical High Risk for Psychosis: A Systematic Review. Frontiers in Psychiatry 12, article number: 620401. (10.3389/fpsyt.2021.620401)
Websites
- Casella, C. et al. 2021. Mutation-related apparent myelin, not axon density, drives white matter differences in premanifest Huntington's disease: evidence from in vivo ultra-strong gradient MRI. [Online]. bioRxiv. (10.1101/2021.11.29.469517) Available at: https://doi.org/10.1101/2021.11.29.469517
Research
Research topics and related papers
Statistical analysis of diffusion MRI data
Mathematical modelling of the topological space represented by brain tractography
Development of tractography-informed frameworks for the representation and analysis of voxel-based data
Project and Funding
Mapping Neurodevelopmental Trajectories for Adult Psychiatric Disorder: ALSPAC-MRI-II
MRC Grant Reference MR/S003436/1.
Research collaborators
Biography
Postgraduate education
Ph.D. Neuroimaging
King's College London, U.K (2014-2019)
M.Sc. Neuroimaging
King's College London, U.K (2013-2014)
Undergraduate education
Licenciatura en Matemáticas (B.Sc + M.Sc. Mathematics)
Universidad de Granada, Spain (1993-1999)
Employment
01/2020 – present: Research Associate
Cardiff University, School of Psychology, Cardiff University Brain Research Imaging Centre (Cardiff UK)
10/2018 – 12/2019: Research Associate
King's College London, (London UK)