Dr Keith Sexton
European Officer
- SextonK@cardiff.ac.uk
- +44 29208 79288
- McKenzie House, Room Floor 6, 30-36 Newport Road, Cardiff, CF24 0DE
Publication
2023
- Goedegebuur, J. et al. 2023. Towards optimal use of antithrombotic therapy of people with cancer at the end of life: a research protocol for the development and implementation of the SERENITY shared decision support tool. Thrombosis Research 228, pp. 54-60. (10.1016/j.thromres.2023.05.008)
2018
- Perry, I., Sexton, K., Prytherch, Z., Jason, B., Judith, Z. and Berube, K. 2018. An in vitro versus in vivo toxicogenomics investigation of prenatal exposures to tobacco smoke. Applied In Vitro Toxicology 4(4), pp. 379-388. (10.1089/aivt.2016.0041)
2012
- Hoogendoorn, B. et al. 2012. Gene and protein responses of human lung tissue explants exposed to ambient particulate matter of different sizes. Inhalation Toxicology 24(14), pp. 966-975. (10.3109/08958378.2012.742600)
2011
- Sexton, K. J., Balharry, D. C., Brennan, P., McLaren, J. E., Brewis, I. A. and Berube, K. A. 2011. Proteomic profiling of human respiratory epithelia by iTRAQ reveals biomarkers of exposure and harm by tobacco smoke components. Biomarkers 16(7), pp. 567-576. (10.3109/1354750X.2011.608855)
2010
- McLaren, J. E. et al. 2010. The TNF-like protein 1A-death receptor 3 pathway promotes macrophage foam cell formation in vitro. Journal of Immunology 184(10), pp. 5827-5834. (10.4049/jimmunol.0903782)
- Price, H. D. et al. 2010. Airborne particles in Swansea, UK: their collection and characterization. Journal of Toxicology and Environmental Health-Part A 73(5-6), pp. 355-367. (10.1080/15287390903442652)
2009
- Balharry, D., Sexton, K., Oreffo, V. and Berube, K. A. 2009. A novel application for Cocoacrisp protein as a biomarker for experimental pulmonary fibrosis. Biomarkers 14(6), pp. 366-371.
2008
- Balharry, D., Sexton, K. J. and Berube, K. A. 2008. An in vitro approach to assess the toxicity of inhaled tobacco smoke components: nicotine, cadmium, formaldehyde and urethane. Toxicology 244(1), pp. 66-76. (10.1016/j.tox.2007.11.001)
- Sexton, K., Balharry, D. and Berube, K. A. 2008. Genomic biomarkers of pulmonary exposure to tobacco smoke components. Pharmacogenetics and Genomics 18(10), pp. 853-860. (10.1097/FPC.0b013e328307bddf)
- Berube, K. A., Hughes, T. G., Prytherch, Z. C., Sexton, K. J., Koshy, L. and Jones, T. P. 2008. An In Vitro Human Tissue Equivalent Model of Respiratory Epithelia for Toxicological Screening of Inhaled Nanoparticles. Presented at: Nanotechnology: towards reducing animal testing, Institute of Nanotechnology, The Royal Society, London, UK, 28-29 May 2008.
- Sexton, K. 2008. Identification of intelligent biomarkers of exposure in the respiratory epithelia to tobacco smoke components. PhD Thesis, Cardiff University.
2007
- Berube, K. A., Balharry, D., Sexton, K. J., Koshy, L. and Jones, T. P. 2007. Combustion-derived nanoparticles: mechanisms of pulmonary toxicity. Clinical and Experimental Pharmacology and Physiology 34(10), pp. 1044-1050. (10.1111/j.1440-1681.2007.04733.x)
- Shao, L. et al. 2007. Associations between particle physicochemical characteristics and oxidative capacity: An indoor PM10 study in Beijing, China. Atmospheric Environment 41(26), pp. 5316-5326. (10.1016/j.atmosenv.2007.02.038)
- Berube, K. A., Balharry, D. C., Hicks, M., Sexton, K. J. and Jones, T. P. 2007. Inter-omic analysis of particulate air pollution. Presented at: 10th Annual UK Review Meeting on Outdoor and Indoor Air Pollution Research, Institute of Environment and Health, Cranfield University, UK, 1-2 May 2007 Presented at Harrison, P. ed.Proceedings of the Tenth Annual UK Review Meeting on Outdoor and Indoor Air Pollution Research, 1–2 May 2007, Cranfield University. Web Report Vol. W24. Cranfield: Institute of Environment and Health, Cranfield University pp. 43-47.
2006
- Berube, K. A. et al. 2006. Characterisation of airborne particulate matter and related mechanisms of toxicity: an experimental approach. In: Ayres, J., Maynard, R. and Richards, R. J. eds. Air Pollution and Health. Air Pollution Reviews Vol. 3. London: Imperial College Press, pp. 69-110.
- Sexton, K. J., Jones, T. P. and Berube, K. A. 2006. Biomarkers of exposure in the respiratory epithelia to tobacco smoke components [Abstract]. Experimental Lung Research 32(3-4), pp. 143. (10.1080/01902140600710603)
- Balharry, D. C., Sexton, K. J. and Berube, K. A. 2006. Characterisation of the dose response of a human airway epithelium model in response to tobacco smoke components. Presented at: European Respiratory Society (ERS) Annual Congress, Munich, Germany, 2-6 September 2006. European Respiratory Society
- Sexton, K. J., Balharry, D. C., Jones, T. P. and Berube, K. A. 2006. The use of toxicogenomics to identify biomarkers of exposure in an airway epithelium model exposed to tobacco smoke components. Presented at: European Respiratory Society (ERS) Annual Congress, Munich, Germany, 2-6 September 2006. European Respiratory Society
2004
- Berube, K. A., Sexton, K. J., Jones, T., Moreno, T., Anderson, S. and Richards, R. J. 2004. The spatial and temporal variations in PM10 mass from six UK homes. Science of the Total Environment 324(1-3), pp. 41-53. (10.1016/j.scitotenv.2003.11.003)
2003
- Berube, K. A., Jones, T. P., Sexton, K. J., Whittaker, A. G. and Richards, R. J. 2003. Quantitative Image Analysis of Urban Airborne Particulate Matter. Proceedings of the Royal Microscopical Society 38(1), pp. 1-10.
2002
- Berube, K., Sexton, K. J., Jones, T. P., Anderson, S. and Richards, R. J. 2002. The life and times of airborne particles: a PM10 travel log [Abstract]. Experimental Lung Research 28(2), pp. 141. (10.1080/019021402753462059)
- Sexton, K. J., Berube, K. A., Jones, T. P. and Richards, R. J. 2002. Quantitative image analysis: the answer to a perfect figure [Abstract]. Experimental Lung Research 28(2), pp. 174. (10.1080/019021402753462059)
2001
- Jones, T. P., Blackmore, P., Leach, M., Berube, K., Sexton, K. J. and Richards, R. J. 2001. Characterisation of Airborne Particles Collected Within and Proximal to an Opencast Coalmine: South Wales, U.K.. Environmental Monitoring and Assessment 75(3), pp. 293-312. (10.1023/A:1014808419171)
- Berube, K., Jones, T. P., Sexton, K. J. and Richards, R. J. 2001. A Comparison of Indoor and Outdoor PM10 Mass and Related particles [Abstract]. Experimental Lung Research 27(1), pp. 77. (10.1080/01902140119933)
Articles
- Goedegebuur, J. et al. 2023. Towards optimal use of antithrombotic therapy of people with cancer at the end of life: a research protocol for the development and implementation of the SERENITY shared decision support tool. Thrombosis Research 228, pp. 54-60. (10.1016/j.thromres.2023.05.008)
- Perry, I., Sexton, K., Prytherch, Z., Jason, B., Judith, Z. and Berube, K. 2018. An in vitro versus in vivo toxicogenomics investigation of prenatal exposures to tobacco smoke. Applied In Vitro Toxicology 4(4), pp. 379-388. (10.1089/aivt.2016.0041)
- Hoogendoorn, B. et al. 2012. Gene and protein responses of human lung tissue explants exposed to ambient particulate matter of different sizes. Inhalation Toxicology 24(14), pp. 966-975. (10.3109/08958378.2012.742600)
- Sexton, K. J., Balharry, D. C., Brennan, P., McLaren, J. E., Brewis, I. A. and Berube, K. A. 2011. Proteomic profiling of human respiratory epithelia by iTRAQ reveals biomarkers of exposure and harm by tobacco smoke components. Biomarkers 16(7), pp. 567-576. (10.3109/1354750X.2011.608855)
- McLaren, J. E. et al. 2010. The TNF-like protein 1A-death receptor 3 pathway promotes macrophage foam cell formation in vitro. Journal of Immunology 184(10), pp. 5827-5834. (10.4049/jimmunol.0903782)
- Price, H. D. et al. 2010. Airborne particles in Swansea, UK: their collection and characterization. Journal of Toxicology and Environmental Health-Part A 73(5-6), pp. 355-367. (10.1080/15287390903442652)
- Balharry, D., Sexton, K., Oreffo, V. and Berube, K. A. 2009. A novel application for Cocoacrisp protein as a biomarker for experimental pulmonary fibrosis. Biomarkers 14(6), pp. 366-371.
- Balharry, D., Sexton, K. J. and Berube, K. A. 2008. An in vitro approach to assess the toxicity of inhaled tobacco smoke components: nicotine, cadmium, formaldehyde and urethane. Toxicology 244(1), pp. 66-76. (10.1016/j.tox.2007.11.001)
- Sexton, K., Balharry, D. and Berube, K. A. 2008. Genomic biomarkers of pulmonary exposure to tobacco smoke components. Pharmacogenetics and Genomics 18(10), pp. 853-860. (10.1097/FPC.0b013e328307bddf)
- Berube, K. A., Balharry, D., Sexton, K. J., Koshy, L. and Jones, T. P. 2007. Combustion-derived nanoparticles: mechanisms of pulmonary toxicity. Clinical and Experimental Pharmacology and Physiology 34(10), pp. 1044-1050. (10.1111/j.1440-1681.2007.04733.x)
- Shao, L. et al. 2007. Associations between particle physicochemical characteristics and oxidative capacity: An indoor PM10 study in Beijing, China. Atmospheric Environment 41(26), pp. 5316-5326. (10.1016/j.atmosenv.2007.02.038)
- Sexton, K. J., Jones, T. P. and Berube, K. A. 2006. Biomarkers of exposure in the respiratory epithelia to tobacco smoke components [Abstract]. Experimental Lung Research 32(3-4), pp. 143. (10.1080/01902140600710603)
- Berube, K. A., Sexton, K. J., Jones, T., Moreno, T., Anderson, S. and Richards, R. J. 2004. The spatial and temporal variations in PM10 mass from six UK homes. Science of the Total Environment 324(1-3), pp. 41-53. (10.1016/j.scitotenv.2003.11.003)
- Berube, K. A., Jones, T. P., Sexton, K. J., Whittaker, A. G. and Richards, R. J. 2003. Quantitative Image Analysis of Urban Airborne Particulate Matter. Proceedings of the Royal Microscopical Society 38(1), pp. 1-10.
- Berube, K., Sexton, K. J., Jones, T. P., Anderson, S. and Richards, R. J. 2002. The life and times of airborne particles: a PM10 travel log [Abstract]. Experimental Lung Research 28(2), pp. 141. (10.1080/019021402753462059)
- Sexton, K. J., Berube, K. A., Jones, T. P. and Richards, R. J. 2002. Quantitative image analysis: the answer to a perfect figure [Abstract]. Experimental Lung Research 28(2), pp. 174. (10.1080/019021402753462059)
- Jones, T. P., Blackmore, P., Leach, M., Berube, K., Sexton, K. J. and Richards, R. J. 2001. Characterisation of Airborne Particles Collected Within and Proximal to an Opencast Coalmine: South Wales, U.K.. Environmental Monitoring and Assessment 75(3), pp. 293-312. (10.1023/A:1014808419171)
- Berube, K., Jones, T. P., Sexton, K. J. and Richards, R. J. 2001. A Comparison of Indoor and Outdoor PM10 Mass and Related particles [Abstract]. Experimental Lung Research 27(1), pp. 77. (10.1080/01902140119933)
Book sections
- Berube, K. A. et al. 2006. Characterisation of airborne particulate matter and related mechanisms of toxicity: an experimental approach. In: Ayres, J., Maynard, R. and Richards, R. J. eds. Air Pollution and Health. Air Pollution Reviews Vol. 3. London: Imperial College Press, pp. 69-110.
Conferences
- Berube, K. A., Hughes, T. G., Prytherch, Z. C., Sexton, K. J., Koshy, L. and Jones, T. P. 2008. An In Vitro Human Tissue Equivalent Model of Respiratory Epithelia for Toxicological Screening of Inhaled Nanoparticles. Presented at: Nanotechnology: towards reducing animal testing, Institute of Nanotechnology, The Royal Society, London, UK, 28-29 May 2008.
- Berube, K. A., Balharry, D. C., Hicks, M., Sexton, K. J. and Jones, T. P. 2007. Inter-omic analysis of particulate air pollution. Presented at: 10th Annual UK Review Meeting on Outdoor and Indoor Air Pollution Research, Institute of Environment and Health, Cranfield University, UK, 1-2 May 2007 Presented at Harrison, P. ed.Proceedings of the Tenth Annual UK Review Meeting on Outdoor and Indoor Air Pollution Research, 1–2 May 2007, Cranfield University. Web Report Vol. W24. Cranfield: Institute of Environment and Health, Cranfield University pp. 43-47.
- Balharry, D. C., Sexton, K. J. and Berube, K. A. 2006. Characterisation of the dose response of a human airway epithelium model in response to tobacco smoke components. Presented at: European Respiratory Society (ERS) Annual Congress, Munich, Germany, 2-6 September 2006. European Respiratory Society
- Sexton, K. J., Balharry, D. C., Jones, T. P. and Berube, K. A. 2006. The use of toxicogenomics to identify biomarkers of exposure in an airway epithelium model exposed to tobacco smoke components. Presented at: European Respiratory Society (ERS) Annual Congress, Munich, Germany, 2-6 September 2006. European Respiratory Society
Thesis
- Sexton, K. 2008. Identification of intelligent biomarkers of exposure in the respiratory epithelia to tobacco smoke components. PhD Thesis, Cardiff University.