Dr David Elwyn Williams
Research Associate
- williamsd37@cardiff.ac.uk
- T0.16, Trevithick Building, The Parade, Newport Road, Cardiff, CF24 3AA
Overview
My research interests are in the application of medical imaging techniques including MRI and video X-Ray to understand the biomechanics of different synovial joints during everyday activities. Being able to quantify and understand the effects of disease and injury to different joints and to assess the efficacy of surgical and non-surgical interventions.
As part of my early postdoctoral research associate work, I was project manager on the design and build of a bespoke Highspeed Biplane Video X-Ray system which has further enhanced our capabilities in the Musculoskeletal Biomechanics Research Facility. I am currently taking on the role of lab manager and radiation protection supervisor for the Biplane Video X-Ray lab and Micro CT Lab.
My current active projects are:
- From brain to biomechanics: Quantifying human dexterity – developing an in-vivo imaging protocol to measure the movement of bones in the hand and wrist
- COMSTIG: Motor cortex magnetic simulation during gait
- Development of a quantitative MRI phantom for knee tissue
- Personalised virtual surgery for optimised knee arthritis treatment
Biography
Publications
2023
- Bowd, J. et al. 2023. Using musculoskeletal modelling to estimate knee joint loading pre and post high tibial osteotomy. Clinical Biomechanics 101, article number: 105855. (10.1016/j.clinbiomech.2022.105855)
2021
- De Vecchis, M., Bowd, J. B., Wilson, C., Whatling, G. M., Holt, C. A. and Williams, D. E. 2021. Hip, knee and ankle kinematics improve after total knee replacement but do not return to normal. Presented at: 2021 OARSI World Congress on Osteoarthritis, Virtual, 29 April - 01 May 2021, Vol. 29. Elsevier pp. S184-S185., (10.1016/j.joca.2021.02.252)
- Esquivel, L., Chapman, G., Holt, C., Brockett, C. and Williams, D. 2021. Development of a protocol to quantify in vivo kinematics of the foot and ankle. Presented at: British Orthopaedic Research Society Annual Meeting (BORS 2020), Virtual, 7-8 September 2020, Vol. 103-B. Vol. SUPP_2. British Editorial Society of Bone and Joint Surgery, (10.1302/1358-992X.2021.2.064)
- Williams, D., Bartlam, H., Roevarran, J. and Holt, C. 2021. Patellofemoral kinematics during different loaded dynamic activities: an in vivo pilot study. Presented at: British Orthopaedic Research Society Annual Meeting (BORS 2020), Virtual, 7-8 September 2020, Vol. 103-B. Vol. SUPP_2. British Editorial Society of Bone and Joint Surgery pp. 54-54., (10.1302/1358-992X.2021.2.054)
2020
- Williams, D. et al. 2020. The relationship between alignment, function and loading in total knee replacement: In-vivo analysis of a unique patient population. Journal of Biomechanics 112, article number: 110042. (10.1016/j.jbiomech.2020.110042)
- Bowd, J. B. et al. 2020. Knee joint contact forces during gait for patients undergoing high tibial osteotomy. Presented at: OARSI 2020 World Congress on Osteoarthritis, Vienna, Austria, 30 April - 3 May 2020, Vol. 28. Vol. Supple. Elsevier pp. s250-s251., (10.1016/j.joca.2020.02.403)
2019
- Sparkes, V. et al. 2019. Comparison of gait, functional activities and patient-reported outcome measures in patients with knee osteoarthritis and healthy adults using 3D motion analysis and activity monitoring: An exploratory case-control analysis. Orthopedic Research and Reviews 11, pp. 129-140. (10.2147/ORR.S199107)
- Jones, P., Woodgate, S., Doheny, E., Biggs, P., Williams, D. and Holt, C. 2019. Do changes in feature selection parameters influence the classification of knee rehabilitation exercises when using body worn accelerometer data?. Osteoarthritis and Cartilage 27(S1), article number: S400. (10.1016/j.joca.2019.02.401)
2018
- Williams, D. E. et al. 2018. How does frontal plane alignment of a total knee replacement influence biomechanical function and loading?. Osteoarthritis and Cartilage 26(S1), pp. S388-S389., article number: 717. (10.1016/j.joca.2018.02.757)
- Holt, C. and Williams, D. 2018. Chapter 6: Biomechanics of the peripheral joints. In: Hochberg, M. C. et al. eds. Rheumatology, 2-Volume Set - 7e., Vol. 7e. Elsevier
- Williams, D. E. 2018. Development and validation of a biplane fluoroscopy system to quantify in-vivo knee kinematics. PhD Thesis, Cardiff University.