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Dr Erik Mire

Research Fellow, Neuroscience & Mental Health Research Institute

School of Medicine

Email:
miree@cardiff.ac.uk
Location:
Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ
Available for postgraduate supervision

My main interest are nicely exposed in the following declaration from UNICEF:

«The first 1,000 days of life - the time spanning roughly between conception and one’s second birthday - is a unique period of opportunity when the foundations of optimum health, growth, and neurodevelopment across the lifespan are established. Yet, too frequently in developing countries, poverty and its attendant condition, malnutrition, weaken this foundation, leading to earlier mortality and significant morbidities such as poor health, and more insidiously, substantial loss of neurodevelopmental potential » 

I aim to understand how early life events, in particular related to diet, impact how our brain is shaped, with the idea that this will be crucial for its function later in life.

2018

2017

2015

2014

2012

2011

2007

Current projects are investigating how maternal obesity influences brain development.

We use state of the art approaches in imaging (lightsheet microscopy and brain clearing) and embryology (in utero electroporation), as well as mouse genetics, FACS, lipidomics, organotypic brain slice culture to study the cellular and molecular processes altered by maternal obesity in the offspring's brain.

The ultimate goal is to provide much needed information on signaling pathways and critical periods to help design preventive/corrective strategies for neuropsychiatirc disorders

External profiles