Dr Lucy Riglin
Lecturer, Division of Psychological Medicine and Clinical Neurosciences
- riglinl@cardiff.ac.uk
- +44 (0)29 2068 8419
- 2.28, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ
Overview
I am a lecturer based at the Wolfson Centre for Young People’s Mental Health and am part of the Child and Adolescent Psychiatry group within the MRC Centre for Neuropsychiatric Genetics and Genomics.
My research investigates young people’s mental health using an interdisciplinary approach, integrating developmental psychopathology, psychiatry and genetic-epidemiology. I am particularly interested in what makes some young people more likely to develop mental health problems and in developmental differences in the aetiology and presentation of mental health problems.
Biography
Publications
2023
- Shakeshaft, A. et al. 2023. Mental-health before and during the COVID-19 pandemic in adults with neurodevelopmental disorders. Journal of Psychiatric Research 159, pp. 230-239. (10.1016/j.jpsychires.2023.01.029)
- Thapar, A., Livingston, L., Eyre, O. and Riglin, L. 2023. Practitioner Review: Attention-deficit hyperactivity disorder and autism spectrum disorder – the importance of depression. Journal of Child Psychology and Psychiatry 64(1), pp. 4-15. (10.1111/jcpp.13678)
- Thapar, A., Livingston, L. A., Eyre, O. and Riglin, L. 2023. Practitioner Review: Attention‐deficit hyperactivity disorder and autism spectrum disorder – the importance of depression. Journal of Child Psychology and Psychiatry 64(1), pp. 4-15. (10.1111/jcpp.13678)
- Riglin, L. et al. 2023. Young-adult social outcomes of attention deficit hyperactivity disorder. Journal of Clinical Psychiatry
2022
- Riglin, L. and Stergiakouli, E. 2022. Mendelian randomisation studies of Attention Deficit Hyperactivity Disorder. JCPP Advances 2(4), article number: e12117. (10.1002/jcv2.12117)
- Sellers, R., Riglin, L., Harold, G. and Thapar, A. 2022. Using genetic designs to identify likely causal environmental contributions to psychopathology. Development and Psychopathology 34(5), pp. 1653-1665. (10.1017/S0954579422000906)
- Pat, N., Yue, W., Anney, R., Riglin, L., Thapar, A. and Argyris, S. 2022. Longitudinally stable, brain-based predictive models mediate the relationships between childhood cognition and socio-demographic, psychological and genetic factors.. Human Brain Mapping 43(18), pp. 5520-5542. (10.1002/hbm.26027)
- Riglin, L. et al. 2022. Early manifestations of genetic liability for ADHD, autism and schizophrenia at ages 18 and 24 months. JCPP Advances 2(3), article number: e12093. (10.1002/jcv2.12093)
- Tobarra‐Sanchez, E., Riglin, L., Agha, S. S., Stergiakouli, E., Thapar, A. and Langley, K. 2022. Preschool development, temperament and genetic liability as early markers of childhood ADHD: A cohort study. JCPP Advances 2(3), article number: e12099. (10.1002/jcv2.12099)
- Havdahl, A. et al. 2022. Associations between pregnancy-related predisposing factors for offspring neurodevelopmental conditions and parental genetic liability to Attention-Deficit/Hyperactivity Disorder, Autism, and Schizophrenia: The Norwegian Mother, Father and Child Cohort Study (MoBa). JAMA Psychiatry 79(8), pp. 799-810. (10.1001/jamapsychiatry.2022.1728)
- Riglin, L. et al. 2022. “Late-onset” ADHD symptoms in young adulthood: is this the same as child-onset ADHD?. Journal of Attention Disorders 26(10), pp. 1271-1282. (10.1177/10870547211066486)
- Wootton, R. E. et al. 2022. Decline in attention-deficit hyperactivity disorder traits over the life course in the general population: trajectories across five population birth cohorts spanning ages 3 to 45 years. International Journal of Epidemiology 51(3), pp. 919-930. (10.1093/ije/dyac049)
- Pat, N., Riglin, L., Anney, R., Wang, Y., Barch, D., Thapar, A. and Stringaris, A. 2022. Motivation and cognitive abilities as mediators between polygenic scores and psychopathology in children. Journal of the American Academy of Child and Adolescent Psychiatry 61(6), pp. 782-795., article number: e3. (10.1016/j.jaac.2021.08.019)
- Niina, A., Eyre, O., Wooton, R., Stergiakouli, E., Thapar, A. and Riglin, L. 2022. Exploring ADHD symptoms and associated impairment across development. Journal of Attention Disorders 26(6), pp. 822-830. (10.1177/10870547211025612)
- Riglin, L. et al. 2022. Assessment of age-at-onset criterion for adult attention-deficit hyperactivity disorder. British Journal of Psychiatry 220(2), pp. 73-75. (10.1192/bjp.2021.122)
- Wimberley, T. et al. 2022. Early-life injuries and the development of attention-deficit/hyperactivity disorder. Journal of Clinical Psychiatry 83(1) (10.4088/JCP.21m14033)
2021
- Dardani, C. et al. 2021. Is genetic liability to ADHD and ASD causally linked to educational attainment?. International Journal of Epidemiology 50(6), pp. 2011-2023. (10.1093/ije/dyab107)
- Eyre, O. et al. 2021. Validation of the short Mood and Feelings Questionnaire in young adulthood. Journal of Affective Disorders 294, pp. 883-888. (10.1016/j.jad.2021.07.090)
- Martin, J. et al. 2021. Sex differences in anxiety and depression in children with ADHD investigating genetic liability and comorbidity. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 186(7), pp. 412-422. (10.1002/ajmg.b.32842)
- Riglin, L. et al. 2021. ADHD and depression: investigating a causal explanation. Psychological Medicine 51(11), pp. 1890-1897. (10.1017/S0033291720000665)
- Riglin, L. et al. 2021. Variable emergence of Autism Spectrum Disorder symptoms from childhood to early adulthood. American Journal of Psychiatry 178(8), pp. 752-760. (10.1176/appi.ajp.2020.20071119)
- Powell, V. et al. 2021. Investigating friendship difficulties in the pathway from ADHD to depressive symptoms. Can parent-child relationships compensate?. Research on Child and Adolescent Psychopathology 49, pp. 1031-1041. (10.1007/s10802-021-00798-w)
- Riglin, L. et al. 2021. Investigating the validity of the strengths and difficulties questionnaire to assess ADHD in young adulthood. Psychiatry Research 301, article number: 113984. (10.1016/j.psychres.2021.113984)
- Leppert, B. et al. 2021. The effect of ADHD on physical health outcomes - a two-sample Mendelian randomization study. American Journal of Epidemiology 190(6), pp. 1047-1055. (10.1093/aje/kwaa273)
- Rice, F. et al. 2021. Pupil mental health, concerns and expectations about secondary school as predictors of adjustment across the transition to secondary school: A longitudinal multi-informant study. School Mental Health 13, pp. 279-298. (10.1007/s12310-021-09415-z)
- Riglin, L. et al. 2021. Investigating attention‐deficit hyperactivity disorder and autism spectrum disorder traits in the general population: What happens in adult life?. Journal of Child Psychology and Psychiatry 62(4), pp. 449-457. (10.1111/jcpp.13297)
2020
- Powell, V. et al. 2020. What explains the link between childhood ADHD and adolescent depression? Investigating the role of peer relationships and academic attainment. European Child and Adolescent Psychiatry 29, pp. 1581-1591. (10.1007/s00787-019-01463-w)
- Thapar, A. and Riglin, L. 2020. The importance of a developmental perspective in Psychiatry: what do recent genetic epidemiological findings show?. Molecular Psychiatry 25, pp. 1631-1639. (10.1038/s41380-020-0648-1)
- Riglin, L. et al. 2020. Using genetics to examine a general liability to childhood psychopathology. Behavior Genetics 50, pp. 213-220. (10.1007/s10519-019-09985-4)
- Wimberle, T. et al. 2020. Genetic liability to ADHD and substance use disorders in individuals with ADHD. Addiction 115(7), pp. 1368-1377. (10.1111/add.14910)
- Leppart, B. et al. 2020. A cross-disorder PRS-pheWAS of 5 major psychiatric disorders in UK Biobank. PLoS Genetics 16(5), article number: e1008185. (10.1371/journal.pgen.1008185)
- Addicoat, A., Thapar, A., Riglin, L., Thapar, A. and Collishaw, S. 2020. Adult mood problems in children with neurodevelopmental problems: evidence from a prospective birth cohort followed to age 50. Social Psychiatry and Psychiatric Epidemiology 55, pp. 351-358. (10.1007/s00127-019-01727-5)
2019
- Ng-Knight, T., Shelton, K. H., Riglin, L., Frederickson, N., McManus, I. C. and Rice, F. 2019. 'Best friends forever'? Friendship stability across school transition and associations with mental health and educational attainment. British Journal of Educational Psychology 89(4), pp. 585-599. (10.1111/bjep.12246)
- Eyre, O., Riglin, L., Stringaris, A., Collishaw, S. and Thapar, A. 2019. Irritability in ADHD: association with later depression symptoms. European Child and Adolescent Psychiatry 28(10), pp. 1375-1384. (10.1007/s00787-019-01303-x)
- Riglin, L. et al. 2019. Identifying novel types of irritability using a developmental genetic approach. American Journal of Psychiatry 176(8), pp. 635-642. (10.1176/appi.ajp.2019.18101134)
- Leppert, B. et al. 2019. Association of maternal neurodevelopmental risk alleles with early-life exposures. JAMA Psychiatry 76(8), pp. 834-842. (10.1001/jamapsychiatry.2019.0774)
- Kendall, K. M. et al. 2019. Association of rare copy number variants with risk of depression. JAMA Psychiatry 76(8), pp. 818-825. (10.1001/jamapsychiatry.2019.0566)
- Rice, F., Riglin, L., Thapar, A. K., Heron, J., Anney, R., O'Donovan, M. C. and Thapar, A. 2019. Characterizing developmental trajectories and the role of neuropsychiatric genetic risk variants in early-onset depression. JAMA Psychiatry 76(3), pp. 306-313. (10.1001/jamapsychiatry.2018.3338)
- Richards, A. et al. 2019. Associations between schizophrenia genetic risk, anxiety disorders and manic/hypomanic episode in a New Zealand longitudinal population cohort study. British Journal of Psychiatry 214(2), pp. 96-102. (10.1192/bjp.2018.227)
- Rice, F. et al. 2019. Adolescent and adult differences in major depression symptom profiles. Journal of Affective Disorders 243, pp. 175-181. (10.1016/j.jad.2018.09.015)
- Riglin, L. et al. 2019. Developmental contributions of schizophrenia risk alleles and childhood peer victimization to early-onset mental health trajectories. American Journal of Psychiatry 176(1), pp. 36-43. (10.1176/appi.ajp.2018.18010075)
2018
- Riglin, L. et al. 2018. The impact of schizophrenia and mood disorder risk alleles on emotional problems: investigating change from childhood to middle age. Psychological Medicine 48(13), pp. 2153-2158. (10.1017/S0033291717003634)
- Cooper, M. et al. 2018. Investigating late-onset ADHD: a population cohort investigation. Journal of Child Psychology and Psychiatry 59(10), pp. 1105-1113. (10.1111/jcpp.12911)
- Martin, J. et al. 2018. Sex-specific manifestation of genetic risk for attention deficit hyperactivity disorder in the general population. Journal of Child Psychology and Psychiatry 59(8), pp. 908-916. (10.1111/jcpp.12874)
- White, E. K. et al. 2018. Twin classroom dilemma: To study together or separately?. Developmental Psychology 54(7), pp. 1244-1254. (10.1037/dev0000519)
2017
- Riglin, L. et al. 2017. Investigating the genetic underpinnings of early-life irritability. Translational Psychiatry 7, article number: e1241. (10.1038/tp.2017.212)
- Riglin, L., Collishaw, S., Richards, A., Thapar, A., Maughan, B., O'Donovan, M. C. and Thapar, A. 2017. Schizophrenia polygenic risk score and psychotic risk detection - authors' reply. The Lancet Psychiatry 4(3), pp. 188-189. (10.1016/S2215-0366(17)30052-4)
- Rice, F., Eyre, O., Riglin, L. and Potter, R. 2017. Adolescent depression and the treatment gap. The Lancet Psychiatry 4(2), pp. 86-87. (10.1016/S2215-0366(17)30004-4)
- Riglin, L., Collishaw, S., Richards, A., Thapar, A. K., Maughan, B., O'Donovan, M. C. and Thapar, A. 2017. Schizophrenia risk alleles and neurodevelopmental outcomes in childhood: a population-based cohort study. Lancet Psychiatry 4(1), pp. 57-62. (10.1016/S2215-0366(16)30406-0)
2016
- Riglin, L. et al. 2016. Association of genetic risk variants with attention-deficit/hyperactivity disorder trajectories in the general population. JAMA Psychiatry 73(12), pp. 1285-1292. (10.1001/jamapsychiatry.2016.2817)
- Ng-Knight, T., Shelton, K. H., Riglin, L., McManus, I., Frederickson, N. and Rice, F. 2016. A longitudinal study of self-control at the transition to secondary school: Considering the role of pubertal status and parenting. Journal of Adolescence 50, pp. 44-55. (10.1016/j.adolescence.2016.04.006)
- Neal, S., Rice, F., Ng-Knight, T., Riglin, L. and Frederickson, N. 2016. Exploring the longitudinal association between interventions to support the transition to secondary school and child anxiety. Journal of Adolescence 50, pp. 31-43. (10.1016/j.adolescence.2016.04.003)
- Riglin, L., Thapar, A., Shelton, K. H., Langley, K., Frederickson, N. and Rice, F. 2016. Profiling depression in childhood and adolescence: the role of conduct problems. Journal of Child Psychology and Psychiatry 57(4), pp. 481-490. (10.1111/jcpp.12465)
- Riglin, L. et al. 2016. Higher cognitive ability buffers stress-related depressive symptoms in adolescent girls. Development and Psychopathology 28(1), pp. 97-109. (10.1017/S0954579415000310)
2015
- McManus, I. C., Ng-Knight, T., Riglin, L., Frederickson, N., Shelton, K. H. and Rice, F. 2015. Doctor, builder, soldier, lawyer, teacher, dancer, shopkeeper, vet: exploratory study of which eleven-year olds would like to become a doctor. BMC Psychology 3(1), article number: 38. (10.1186/s40359-015-0094-z)
- Rice, F., Rawal, A., Riglin, L., Lewis, G., Lewis, G. and Dunsmuir, S. 2015. Examining reward-seeking, negative self-beliefs and over-general autobiographical memory as mechanisms of change in classroom prevention programs for adolescent depression. Journal of Affective Disorders 186, pp. 320-327. (10.1016/j.jad.2015.07.019)
2014
- Rawal, A., Riglin, L., Ng-Knight, T., Collishaw, S., Thapar, A. and Rice, F. 2014. A longitudinal high-risk study of adolescent anxiety, depression and parent-severity on the developmental course of risk-adjustment. Journal of Child Psychology and Psychiatry 55(11), pp. 1270-1278. (10.1111/jcpp.12279)
- Riglin, L., Petrides, K., Frederickson, N. and Rice, F. 2014. The relationship between emotional problems and subsequent school attainment: A meta-analysis. Journal of Adolescence 37(4), pp. 335-346. (10.1016/j.adolescence.2014.02.010)
2013
- Riglin, L., Frederickson, N., Shelton, K. H. and Rice, F. 2013. A longitudinal study of psychological functioning and academic attainment at the transition to secondary school. Journal of Adolescence 36(3), pp. 507-517. (10.1016/j.adolescence.2013.03.002)
