Dr Timothy Stone

2019

• Lee, J.et al. 2019. CAG repeat not polyglutamine length determines timing of Huntington’s disease onset. Cell 178(4), pp. 887-900.e14. (10.1016/j.cell.2019.06.036)

2018

• Holmans, P. and Stone, T. 2018. Using genomic data to find disease-modifying loci in Huntington's Disease (HD). In: Precious, S. V., Rosser, A. E. and Dunnett, S. eds. Huntington’s Disease., Vol. 1780. Methods in Molecular Biology Humana Press, pp. 443-461., (10.1007/978-1-4939-7825-0_20)

2017

• Welton, J. L.et al. 2017. Cerebrospinal fluid extracellular vesicle enrichment for protein biomarker discovery in neurological disease; multiple sclerosis. Journal of Extracellular Vesicles 6(1), article number: 1369805. (10.1080/20013078.2017.1369805)
• Lopez-Anton, M.et al. 2017. miR-21 promotes fibrogenesis in peritoneal dialysis. American Journal of Pathology 187(7), pp. 1537-1550. (10.1016/j.ajpath.2017.03.007)
• Hensman Moss, D. J.et al. 2017. Huntington's disease blood and brain show a common gene expression pattern and share an immune signature with Alzheimer's disease. Scientific Reports 7, pp. -., article number: 44849. (10.1038/srep44849)
• Bowles, K. R.et al. 2017. SMAD transcription factors are altered in cell models of HD and regulate HTT expression. Cellular Signalling 31, pp. 1-14. (10.1016/j.cellsig.2016.12.005)

2016

• Miller, J. R. C.et al. 2016. RNA-Seq of Huntington's disease patient myeloid cells reveals innate transcriptional dysregulation associated with proinflammatory pathway activation. Human Molecular Genetics 25(14), pp. 2893-2904. (10.1093/hmg/ddw142)

2015

• Bayram-Weston, Z.et al. 2015. Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington's disease are not reflected in mutant Huntingtin inclusion prevalence. BMC Genomics 16, pp. -., article number: 1079. (10.1186/s12864-015-2251-4)
• Lee, J. M.et al. 2015. Identification of genetic factors that modify clinical onset of Huntington's disease. Cell 162(3), pp. 516-526. (10.1016/j.cell.2015.07.003)
• Jones, L.et al. 2015. Convergent genetic and expression data implicate immunity in Alzheimer's disease. Alzheimer's and Dementia 11(6), pp. 658-671. (10.1016/j.jalz.2014.05.1757)

2014

• Rosas, M.et al. 2014. The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal. Science 344(6184), pp. 645-648. (10.1126/science.1251414)
• Webber, J.et al. 2014. Proteomics analysis of cancer exosomes using a novel modified aptamer-based array (SOMAscanTM) platform. Molecular and Cellular Proteomics 13(4), pp. 1050-1064. (10.1074/mcp.M113.032136)