Professor Simon Reed

2020

• Wang, D.et al. 2020. LRIK interacts with the Ku70–Ku80 heterodimer enhancing the efficiency of NHEJ repair. Cell Death and Differentiation 27, pp. 3337-3353. (10.1038/s41418-020-0581-5)

2018

• van Eijk, P.et al. 2018. Nucleosome remodeling at origins of global genome?nucleotide excision repair occurs at the boundaries of higher-order chromatin structure. Genome Research 29(1), pp. 74-84. (10.1101/gr.237198.118)
• Wang, D.et al. 2018. XPF plays an indispensable role in relieving silver nanoparticle induced DNA damage stress in human cells. Toxicology Letters 288, pp. 44-54. (10.1016/j.toxlet.2018.02.022)
• Piasecka, A.et al. 2018. The Y. bercovieri Anbu crystal structure sheds light on the evolution of highly (pseudo)symmetric multimers. Journal of Molecular Biology 430(5), pp. 611-627. (10.1016/j.jmb.2017.11.016)

2017

• Van Eijk, P.et al. 2017. Integrated microarray-based tools for detection of genomic DNA damage and repair mechanisms. In: Muzi-Falconi, M. and Brown, G. W. eds. Genome Instability. Methods in Molecular Biology., Vol. 1672. New York, NY: Humana Press, pp. 77., (10.1007/978-1-4939-7306-4_7)

2016

• Yu, S.et al. 2016. Global genome nucleotide excision repair is organized into domains that promote efficient DNA repair in chromatin. Genome Research 26, pp. 1376-1387. (10.1101/gr.209106.116)

2015

• Waters, R., van Eijk, P. and Reed, S. 2015. Histone modification and chromatin remodeling during NER. DNA Repair 36, pp. 105-113. (10.1016/j.dnarep.2015.09.013)
• Menzies, G.et al. 2015. Base damage, local sequence context and TP53 mutation hotspots: a molecular dynamics study of benzo[a]pyrene induced DNA distortion and mutability. Nucleic Acids Research 43(19), pp. 9133-9146. (10.1093/nar/gkv910)
• Zhou, Z.et al. 2015. UV induced ubiquitination of the yeast Rad4–Rad23 complex promotes survival by regulating cellular dNTP pools. Nucleic Acids Research 43(15), pp. 7360-7370. (10.1093/nar/gkv680)
• Bennett, M. R.et al. 2015. Sandcastle: software for revealing latent information in multiple experimental ChIP-chip datasets via a novel normalisation procedure. Scientific Reports 5, article number: 13395. (10.1038/srep13395)
• Powell, J. R.et al. 2015. 3D-DIP-Chip: a microarray-based method to measure genomic DNA damage. Scientific Reports 5, article number: 7975. (10.1038/srep07975)

2013

• Colmont, C. S.et al. 2013. Human basal cell carcinoma tumor-initiating cells are resistant to etoposide [Letter]. Journal of Investigative Dermatology 134(3), pp. 867-870. (10.1038/jid.2013.377)
• Yu, Y.et al. 2013. Histone variant Htz1 promotes histone H3 acetylation to enhance nucleotide excision repair in Htz1 nucleosomes. Nucleic Acids Research 41(19), pp. 9006-9019. (10.1093/nar/gkt688)
• Colmont, C. S.et al. 2013. CD200-expressing human basal cell carcinoma cells initiate tumor growth. Proceedings of the National Academy of Sciences of the United States of America 110(4), pp. 1434-1439. (10.1073/pnas.1211655110)
• Powell, J.et al. 2013. Functional genome-wide analysis: a technical review, its developments and its relevance to cancer research. Recent Patents on DNA and Gene Sequences 7(2), pp. 157-166. (10.2174/18722156113079990020)

2012

• Waters, R.et al. 2012. Nucleotide excision repair in cellular chromatin: studies with yeast from nucleotide to gene to genome. International Journal of Molecular Sciences 13(9), pp. 11141-11164. (10.3390/ijms130911141)
• Bennett, M. R.et al. 2012. Bioinformatic analyses of genome wide nucleotide excision repair datasets in Saccharomyces cerevisiae [Abstract]. Mutagenesis 27(1), pp. 121. (10.1093/mutage/ger068)
• Waters, R.et al. 2012. Emerging technologies in genotoxicity testing: measuring DNA damage in entire genomes at high resolution [Abstract]. Mutagenesis 27(1), pp. 112. (10.1093/mutage/ger068)

2011

• Silver, H. R.et al. 2011. A role for SUMO in nucleotide excision repair. DNA Repair 10(12), pp. 1243-1251. (10.1016/j.dnarep.2011.09.013)
• Yu, S.et al. 2011. How chromatin is remodelled during DNA repair of UV-induced DNA damage in Saccharomyces cerevisiae. PLoS Genetics 7(6), article number: e1002124. (10.1371/journal.pgen.1002124)
• Teng, Y.et al. 2011. A novel method for the genome-wide high resolution analysis of DNA damage. Nucleic Acids Research 39(2), article number: e10. (10.1093/nar/gkq1036)
• Reed, S. H. 2011. Nucleotide excision repair in chromatin: damage removal at the drop of a HAT. DNA Repair 10(7), pp. 734-742. (10.1016/j.dnarep.2011.04.029)

2010

• Irizar, M. A.et al. 2010. Silenced yeast chromatin is maintained by Sir2 in preference to permitting histone acetylations for efficient NER. Nucleic Acids Research 38(14), pp. 4675-4686. (10.1093/nar/gkq242)

2009

• Yu, S.et al. 2009. ABF1-binding sites promote efficient global genome nucleotide excision repair. Journal of Biological Chemistry 284(2), pp. 966-973. (10.1074/jbc.M806830200)
• Waters, R.et al. 2009. Tilting at windmills? The nucleotide excision repair of chromosomal DNA. DNA Repair 8(2), pp. 146-152. (10.1016/j.dnarep.2008.11.001)
• Teng, Y.et al. 2009. Lux ex tenebris: Nucleotide resolution DNA repair and nucleosome mapping. Methods 48(1), pp. 23-34. (10.1016/j.ymeth.2009.02.017)

2008

• Teng, Y.et al. 2008. Saccharomyces cerevisiae Rad16 mediates ultraviolet-dependent histone H3 acetylation required for efficient global genome nucleotide-excision repair. EMBO Reports 9(1), pp. 97-102. (10.1038/sj.embor.7401112)

2007

• Teng, Y.et al. 2007. Saccharomyces cerevisiae Rad16 mediates UV dependent histone H3 acetylation required for efficient global genome nucleotide excision repair. Technical Report.

2006

• Reed, S. H.et al. 2006. Distinct functions of the ubiquitin-proteasome pathway influence nucleotide excision repair. Embo J 25, pp. 2529-2538. (10.1038/sj.emboj.7601120)

2005

• Yu, Y.et al. 2005. UV irradiation stimulates histone acetylation and chromatin remodeling at a repressed yeast locus. Proceedings of the National Academy of Sciences 102(24), pp. 8650-8655. (10.1073/pnas.0501458102)

2004

• Yu, S.et al. 2004. The yeast Rad7/Rad16/Abf1 complex generates superhelical torsion in DNA that is required for nucleotide excision repair. DNA repair 3(3), pp. 277-287. (10.1016/j.dnarep.2003.11.004)

2001

• Gillette, T. G.et al. 2001. The 19S complex of the proteasome regulates nucleotide excision repair in yeast. Genes & Development 15(12), pp. 1528-1539. (10.1101/gad.869601)