Professor Simon Reed

Professor

School of Medicine

: reedsh1@cardiff.ac.uk
: +44 (0)29 2068 7336
: UHW Main Building

Publications
Biography

2020

Wang, D.et al. 2020. LRIK interacts with the Ku70–Ku80 heterodimer enhancing the efficiency of NHEJ repair. Cell Death and Differentiation 27, pp. 3337-3353. (10.1038/s41418-020-0581-5)

2018

van Eijk, P.et al. 2018. Nucleosome remodeling at origins of global genome?nucleotide excision repair occurs at the boundaries of higher-order chromatin structure. Genome Research 29(1), pp. 74-84. (10.1101/gr.237198.118)
Wang, D.et al. 2018. XPF plays an indispensable role in relieving silver nanoparticle induced DNA damage stress in human cells. Toxicology Letters 288, pp. 44-54. (10.1016/j.toxlet.2018.02.022)
Piasecka, A.et al. 2018. The Y. bercovieri Anbu crystal structure sheds light on the evolution of highly (pseudo)symmetric multimers. Journal of Molecular Biology 430(5), pp. 611-627. (10.1016/j.jmb.2017.11.016)

2017

Van Eijk, P.et al. 2017. Integrated microarray-based tools for detection of genomic DNA damage and repair mechanisms. In: Muzi-Falconi, M. and Brown, G. W. eds. Genome Instability. Methods in Molecular Biology., Vol. 1672. New York, NY: Humana Press, pp. 77., (10.1007/978-1-4939-7306-4_7)

2016

Yu, S.et al. 2016. Global genome nucleotide excision repair is organized into domains that promote efficient DNA repair in chromatin. Genome Research 26, pp. 1376-1387. (10.1101/gr.209106.116)

2015

Waters, R., van Eijk, P. and Reed, S. 2015. Histone modification and chromatin remodeling during NER. DNA Repair 36, pp. 105-113. (10.1016/j.dnarep.2015.09.013)
Menzies, G.et al. 2015. Base damage, local sequence context and TP53 mutation hotspots: a molecular dynamics study of benzo[a]pyrene induced DNA distortion and mutability. Nucleic Acids Research 43(19), pp. 9133-9146. (10.1093/nar/gkv910)
Zhou, Z.et al. 2015. UV induced ubiquitination of the yeast Rad4–Rad23 complex promotes survival by regulating cellular dNTP pools. Nucleic Acids Research 43(15), pp. 7360-7370. (10.1093/nar/gkv680)
Bennett, M. R.et al. 2015. Sandcastle: software for revealing latent information in multiple experimental ChIP-chip datasets via a novel normalisation procedure. Scientific Reports 5, article number: 13395. (10.1038/srep13395)
Powell, J. R.et al. 2015. 3D-DIP-Chip: a microarray-based method to measure genomic DNA damage. Scientific Reports 5, article number: 7975. (10.1038/srep07975)

2013

Colmont, C. S.et al. 2013. Human basal cell carcinoma tumor-initiating cells are resistant to etoposide [Letter]. Journal of Investigative Dermatology 134(3), pp. 867-870. (10.1038/jid.2013.377)
Yu, Y.et al. 2013. Histone variant Htz1 promotes histone H3 acetylation to enhance nucleotide excision repair in Htz1 nucleosomes. Nucleic Acids Research 41(19), pp. 9006-9019. (10.1093/nar/gkt688)
Colmont, C. S.et al. 2013. CD200-expressing human basal cell carcinoma cells initiate tumor growth. Proceedings of the National Academy of Sciences of the United States of America 110(4), pp. 1434-1439. (10.1073/pnas.1211655110)
Powell, J.et al. 2013. Functional genome-wide analysis: a technical review, its developments and its relevance to cancer research. Recent Patents on DNA and Gene Sequences 7(2), pp. 157-166. (10.2174/18722156113079990020)

2012

Waters, R.et al. 2012. Nucleotide excision repair in cellular chromatin: studies with yeast from nucleotide to gene to genome. International Journal of Molecular Sciences 13(9), pp. 11141-11164. (10.3390/ijms130911141)
Bennett, M. R.et al. 2012. Bioinformatic analyses of genome wide nucleotide excision repair datasets in Saccharomyces cerevisiae [Abstract]. Mutagenesis 27(1), pp. 121. (10.1093/mutage/ger068)
Waters, R.et al. 2012. Emerging technologies in genotoxicity testing: measuring DNA damage in entire genomes at high resolution [Abstract]. Mutagenesis 27(1), pp. 112. (10.1093/mutage/ger068)

2011

Silver, H. R.et al. 2011. A role for SUMO in nucleotide excision repair. DNA Repair 10(12), pp. 1243-1251. (10.1016/j.dnarep.2011.09.013)
Yu, S.et al. 2011. How chromatin is remodelled during DNA repair of UV-induced DNA damage in Saccharomyces cerevisiae. PLoS Genetics 7(6), article number: e1002124. (10.1371/journal.pgen.1002124)
Teng, Y.et al. 2011. A novel method for the genome-wide high resolution analysis of DNA damage. Nucleic Acids Research 39(2), article number: e10. (10.1093/nar/gkq1036)
Reed, S. H. 2011. Nucleotide excision repair in chromatin: damage removal at the drop of a HAT. DNA Repair 10(7), pp. 734-742. (10.1016/j.dnarep.2011.04.029)

2010

Irizar, M. A.et al. 2010. Silenced yeast chromatin is maintained by Sir2 in preference to permitting histone acetylations for efficient NER. Nucleic Acids Research 38(14), pp. 4675-4686. (10.1093/nar/gkq242)

2009

Yu, S.et al. 2009. ABF1-binding sites promote efficient global genome nucleotide excision repair. Journal of Biological Chemistry 284(2), pp. 966-973. (10.1074/jbc.M806830200)
Waters, R.et al. 2009. Tilting at windmills? The nucleotide excision repair of chromosomal DNA. DNA Repair 8(2), pp. 146-152. (10.1016/j.dnarep.2008.11.001)
Teng, Y.et al. 2009. Lux ex tenebris: Nucleotide resolution DNA repair and nucleosome mapping. Methods 48(1), pp. 23-34. (10.1016/j.ymeth.2009.02.017)

2008

Teng, Y.et al. 2008. Saccharomyces cerevisiae Rad16 mediates ultraviolet-dependent histone H3 acetylation required for efficient global genome nucleotide-excision repair. EMBO Reports 9(1), pp. 97-102. (10.1038/sj.embor.7401112)

2007

Teng, Y.et al. 2007. Saccharomyces cerevisiae Rad16 mediates UV dependent histone H3 acetylation required for efficient global genome nucleotide excision repair. Technical Report.

2006

Reed, S. H.et al. 2006. Distinct functions of the ubiquitin-proteasome pathway influence nucleotide excision repair. Embo J 25, pp. 2529-2538. (10.1038/sj.emboj.7601120)

2005

Yu, Y.et al. 2005. UV irradiation stimulates histone acetylation and chromatin remodeling at a repressed yeast locus. Proceedings of the National Academy of Sciences 102(24), pp. 8650-8655. (10.1073/pnas.0501458102)

2004

Yu, S.et al. 2004. The yeast Rad7/Rad16/Abf1 complex generates superhelical torsion in DNA that is required for nucleotide excision repair. DNA repair 3(3), pp. 277-287. (10.1016/j.dnarep.2003.11.004)

2001

Gillette, T. G.et al. 2001. The 19S complex of the proteasome regulates nucleotide excision repair in yeast. Genes & Development 15(12), pp. 1528-1539. (10.1101/gad.869601)