Skip to main content

Dr Kathryn Hughes

Clinical Lecturer

School of Medicine

+44 (0)29 2068 7246
Neuadd Meirionnydd
Available for postgraduate supervision

I am a GP and Senior Clinical Research Fellow in PRIME Centre Wales and the Division of Population Medicine.

My research interests are in the diagnosis and management of common problems seen in UK General Practice, particularly infections. I am co-lead of the Infections theme in PRIME.

I have worked on several studies concerning the diagnosis of urinary tract infections (UTI) in children, including prospective cohort studies and studies using routinely collected electronic health records.


  • PhD School of Medicine, Cardiff University 2013 (Childhood UTI)
  • Dip Epi Diploma in Epidemiology London School of Hygiene and Tropical Medicine 2009
  • PCME Postgraduate Certificate of Medical Education 2006
  • MRCGP (Merit) Membership of the Royal College of General Practitioners 2003
  • DFFP Diploma of the Faculty of Family Planning 2003
  • DCH Diploma in Child Health 2001
  • MB BCh Medical Degree 1998 Cardiff University

Overview of Career

  • Sep 2016 – present: Senior Clinical Research Fellow, PRIME Centre Wales, School of Medicine, Cardiff University & GP
  • Sep 2015 – Sep 2016: Maternity leave
  • May 2005 – Sep 2015: Clinical Lecturer, School of Medicine, Cardiff University & GP (Partner Blaen-y-cwm Surgery Jan 2010-Dec 2014)
  • Oct 2003 – May 2005: Associate Academic General Practitioner (Academic Fellow), School of Medicine, Cardiff University & GP
  • Aug 2003 - Oct 2003: Locum General Practitioner
  • Feb 2000 - Aug 2003: General Practice Vocational Training Scheme (Royal Glamorgan Hospital)
  • Aug 1999 - Feb 2000: SHO in Accident and Emergency, Royal Gwent Hospital
  • Feb1999 – Aug 1999: HO in Medicine (respiratory) Princess of Wales Hospital
  • Aug 1998 – Feb 1999: HO in General Surgery Royal Gwent Hospital

Honours and awards

Research paper awards

2016 RCGP Research Paper of the year Category 3: Children, Reproduction, genetics, infections

Hay AD, Sterne JA, Hood K, Little P, Delaney B, Hollingworth W, et al. Improving the Diagnosis and Treatment of Urinary Tract Infection in Young Children in Primary Care: Results from the DUTY Prospective Diagnostic Cohort Study. Annals of family medicine. 2016;14(4):325-36.

2015 RCGP Research Paper of the year Category 3: Children, Reproduction, genetics, infections

Butler CC, O'Brien K, Pickles T, Hood K, Wootton M, Howe R, Waldron CA, Thomas-Jones E, Hollingworth W, Little P, Van Der Voort J, Dudley J, Rumsby K, Downing H, Harman K, Hay AD; DUTY study team. Childhood urinary tract infection in primary care: a prospective observational study of prevalence, diagnosis, treatment, and recovery. Br J Gen Pract. 2015 Apr;65(633):e217-23

Professional memberships

Royal College of General Practitioners (since 2003)

Committees and reviewing

  • Health and Care Research Wales All Wales Prioritisation Panel member (Aug 2019-present)








My teaching areas include infections, primary care research, quantitative research methods and communication skills.

I am currently involved in teaching on the following courses:

  • MB BCh C21 through Evidence based Medicine Tutorial sessions, SSCs and ISCE clinical examinations.
  • Intercalated BSc in Population Medicine: co-lead Short term conditions module & Project Supervisor

My main research interest is in the diagnaosis and management of infections in primary care, particularly urinary tract infections (UTI). I am also interested in other common infections, antibiotic use and antimicrobial resistance, and the diagnosis/identification of serious illness in children.

I am particularly interested in taking forward our exploratory work concerning the urinary microbiome in children and adults with and without UTI.


Title: Wales Centre for Primary and Emergency (including Unscheduled) Care Research (PRIME) and Care Research Wales, Centre Extension. Applicants: Edwards A, Ahmed H, Brain K, Burton C, Carson-Stevens A, Chestnutt I, Davies F, Evans B, Francis N, Ford D, Gal M, Harris-Mayes R, Hiscock J, Hughes D, Hughes K, Jones J, Joseph-Williams N, Kenkre K, Khanom A, Kingston M, Law R, Lewis R, Llewellyn M, Nelson A, North R, Northway R, Phillips R, Pontin D, Poolman M, Porter A, Rees N, Rolph M, Smith S, Snooks H, Spasić I, Thomas-Jones E, Todd S, Wallace C, Watkins A, Wilkinson C, Williams M, Wood. Funder: Health and Care Research Wales. Amount: £4,634,746. Duration: April 2020-March 2025

Title: Quantitative mapping of the microbiome and resistome in urinary tract infection among women: a pump-priming interdisciplinary study Applicants: Gadalla A, Francis N, Connor T, Marchesi J, Hughes K, E Mahenthiralingam, Butler C. Funder: ISSF3 Population Award, Cardiff University/Wellcome. Amount: £43,322 . Duration: April 2019-July 2020

Title: Wales Centre for Primary and Emergency (including Unscheduled) Care Research (PRIME) and Care Research Wales, Centre Extension. Applicants: Edwards A, Brain K, Bulger J, Calder G, Carson-Stevens A, Chestnutt I, Davies F, van Deursen R, Evans B, Ford D, Francis N, Gal M, Gobat N, Harris-Mayes R, Hiscock J, Hood K, Hughes D, Hughes K, Joseph-Williams N, Kenkre J, Khanom A, Kingston M, Lewis R, North R, Phillips R, Porter A, Rees N, Rycroft-Malone J, Smith S, Smits S, Snooks H, Spasić I, Thomson C, Ud Din N, Wallace C, Watkins A, Wilkinson C, Williams M, Williams N, Wood F Amount: £1,799,934.62 Duration: 1/4/18 – 31/03/20

Title: The LUCI study: The Long-term follow-up of Urinary tract infection (UTI) in Children. Applicants: O’Brien K, Cannings-John R, Paranjothy S, Francis N, Hay A, Butler C, Hood K. Funder:Health and Care Research Wales, Health Research Award Amount: £248,122. Duration: Oct 2016-June 2019

Title: Helpmedoit: A web and text based intervention to facilitate social support to achieve and maintain health related behaviour change. Applicants: Simpson S, Morgan Trimmer S, O’Brien K, Murphy S, Kelly M, Moore L, John E, McConnachie A, Mcintosh E Dunder: NIHR PHR Award Amount: £414,000. Duration: Feb 2015-July 2017.

Title: Symptoms of uncomplicated UTI in women presenting to general practice: exploration of causation in culture negative urine: The 'Missing link' study. Applicants: Butler C, Eberl M, Francis N, Gal M, Gregory C, Hood K, Howe R, Marchesi J, O’Brien K, Topley N, Wooton M. Funder: Wales School of Primary Care Research. Amount: £22,699 Duration:April 2014-2015

Title: Development of Polymerase Chain Reaction (PCR)/DNA pyrosequencing methods for the laboratory identification and analysis of urinary tract infections. Applicants: O’Brien K, Gregory C, Marchesi J, Francis N, Butler C. Funder: WellcomeTrust/ ISSF SEEDCORN Award. Amount: £50,000 Duration: June 2012-15

Title: DUTY: The Diagnosis of Urinary Tract Infection in Young Children Study. Applicants: Hay A, Butler C, Little P, Hood K, MacGowan A, Sterne J, Hollingworth W, Howe R, Whiting P, O’Brien K, Dudley J, van der Voort J, Montgomery A, Benger J, Fletcher M. Funder: NIHR HTA Award Amount: £3,255,125. Duration: Jan 2010-Dec 2016

Title: Microbiology and Infection Translational Research Group (MITReG). Applicants: Baille L, Barnes R, Brazier J, Bugert J, Butler C, Chalmers R, Cohen D, Corden S, Davies A, Davies E, Denyer S, Dunstan F, Eberl M, Edwards A, Evans M, Guy E, Hall J, Hastings M, Hay A, Heginbothom M, Henry R, Howe R, Hughes D, Kotecha S, Leaper D, Lewis M, Lovering A, Lyons M, Lyons R, MacGowan A, Mack D, Mahenthiralingam E, Maillard J, Marchesi J, Mason B, McGuigan C, O’Brien K, Price D, Sewell A, Taylor P, Thomas D, Topley N, Walsh T, Weightman A, White L, Wilkinson G, Williams D, Wootton M Funder: NISCHR Amount: £342,867 Duraton: March 2010- March 2015

Title: The Epidemiology of Urinary Tract Infection (UTI) in Children with Acute Illness in Primary Care (EURICA study). Applicants: Butler C, O’Brien K, Edwards A, Hood K. Funder: joint WAG/MRC Health Partnership Award Amount: £139,897. Duration: April 2008-March 2012

I am interested in supervising PhD students in the areas of:

  • Primary care
  • Infections
  • Urinary tract infections
  • Antimicrobial resistance
  • Urinary microbiome 
  • Point of care diagnostic tests

Current supervision

Portrait shot of a smiling man

Adam Williams

Research student