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 Hayley Moss

Hayley Moss

Research Assistant, Division of Psychological Medicine and Clinical Neurosciences

School of Medicine

Email:
mosshm@cardiff.ac.uk
Telephone:
+44 (0)29 2068 8354
Location:
2.06, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ

22q11.2 deletion syndrome (22q11.2DS) results from a chromosomal alteration which involves the loss of DNA. It is one of the most frequently occurring deletion syndromes affecting approximately 1:4000 live births. 22q11.2DS has been associated with very high risk of mental illness, for example, 22q11.2DS is one of the strongest known risk factors for schizophrenia: studies in adult patients have shown rates close to of 25%, compared to 1% in the general population. Furthermore, children with 22q11.2DS are more likely to have developmental delays, learning difficulties, behavioural problems and psychiatric disorders.

To gain better understanding of the psychiatric phenotype of 22q11.2DS and the impact that it has, I will be looking at psychiatric data, along with measures of incapacity and function to investigate whether children with sub-diagnostic threshold symptoms of psychiatric disorders are as impaired as children who reach criteria for a diagnosis of a psychiatric disorder. This will be beneficial both clinically and for the wider public domain.

PhD topic

Exploring psychoptathological phenotype in children with genetic syndromes that confer risk of psychiatric disorders.

2018

2017