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Dr Steven Knapper

Dr Steven Knapper

Clinical Reader

School of Medicine

+44 29207 45379
UHW Main Building
Media commentator

I am an academic clinical haematologist, combining the role of Clinical Reader in the Institute of Cancer and Genetics at Cardiff University School of Medicine with clinical work as an Honorary Consultant Haematologist at the University Hospital of Wales where I currently act as haematological cancer lead clinician.

My clinical practice is predominantly in myeloid haematological cancers, particularly acute myeloid leukaemia, the myeloproliferative neoplasms and myelodysplastic syndromes. My chief research interest lies in the development of targeted therapeutic agents in myeloid malignancies; this includes pre-clinical laboratory studies on FLT3 inhibition, TAM kinase inhibition and reactive oxygen species manipulation and clinical research including 'back to bench' laboratory projects running alongside clinical trials.

I am extensively involved in the development of clinical research at a national level through membership of the UK NCRI AML and Myeloproliferative Neoplasms Clinical Study Groups. I co-lead on early phase clinical trials within the Welsh Cancer Research Centre. I am chief investigator of MONOCLE - a UK study of tefinostat in chronic myelomonocytic leukaemia, and co-chief investigator of the AML18 trial. My other roles include Cardiff lead for the Bloodwise Trials Acceleration Programme and lead of Cardiff University School of Medicine medical undergraduate haematology teaching.

Education and Qualifications

2006   DM (Christ Church, Oxford)

2006   FRCPath (Royal College of Pathologists)

1999   MRCP (Royal College of Physicians – London)

1996   BMBCh (Christ Church, Oxford)

1993   BA / MA (Hons) (Trinity College, Cambridge)

Career Overview

2016 - present: Clinial Reader in Haematology (Cardiff University Schoold of Medicine) and Honorary Consultant Haematologist (Cardiff & Vale University Health Board)

2007 - 2016: Clinical Senior Lecturer in Haematology (Cardiff University) and Honorary Consultant Haematologist (C&V UHB)

2004 - 2007: Clinical Lecturer in Haematology (Cardiff University)

2001- 2006: Specialist Registar in Haematology (All Wales Higher Training Programme)

2000 - 2001: Locum Specialist Registar in Haematology (South West Regional Training Programme - Bristol)

1997 - 2000: Senior House Officer Medicine (Taunton & Somerset Hospital)

Professional memberships

Fellow of Royal College of Pathologists

Member of Royal College of Physicians (London)

UK NCRN Acute Myeloid Leukaemia Clinical Study Group

UK NCRN Myeloproliferative Neoplasms Clinical Study Group

British Society for Haematology

American Society of Hematology















Areas of expertise