Dr Jonathan Hewitt
Clinical Senior Lecturer
- Media commentator
Overview
I am interested in all aspects of research in Older People, my areas of interest are stroke, diabetes and large scale epidemiology, especially biobanking.
I am the course leader for the MSc in Ageing Health and Disease. This course requires wide knowledge of all areas of clinical gerontology. I particularly enjoy supervising the dissertation section.
Vascular disease is close to my heart; my PhD was in diabetes in the older person and I spent a year on sabbatical in Glasgow University, focusing on stroke and hypertension.
I find systematic and Cochrane reviews particularly enjoyable. I am currently working on four systematic reviews in very diverse areas; dance therapy, multitasking, urate and laparoscopic surgery in the elderly. I also enjoy performing Cochrane reviews and I am working on my third one, have completed one in general surgery and one in general medicine.
Surgical disease in the Elderly is another area of interest. The epidemiology of surgical conditions, especially general surgical conditions, is very sparse in the older person. I have recently formed a research development group in this area and we are hoping to start large scale observational data collection and hopefully future RCTs.
My clinical responsibilities are based in Ystrad Mynach Fawr, where I am a general, geriatric and stroke physician. A job I really like doing too!
Publication
2024
- Verduri, A., Clini, E., Carter, B. and Hewitt, J. 2024. Impact of frailty on symptom burden in chronic obstructive pulmonary disease. Journal of Clinical Medicine 13(4), article number: 984. (10.3390/jcm13040984)
2023
- Verduri, A., Carter, B., Laraman, J., Rice, C., Clini, E., Maskell, N. A. and Hewitt, J. 2023. Frailty and its influence on mortality and morbidity in COPD: A systematic review and meta-analysis. Internal and Emergency Medicine 18, pp. 2423-2434. (10.1007/s11739-023-03405-6)
- Masoli, J. A. H. et al. 2023. New horizons in the role of digital data in the healthcare of older people. Age and Ageing 52(8), article number: afad134. (10.1093/ageing/afad134)
- Verduri, A. et al. 2023. Frailty prevalence and association with clinical outcomes in interstitial lung disease, asthma, and pleural disease. Geriatrics 8(4), article number: 82. (10.3390/geriatrics8040082)
- Humphry, N., Jones, M., Goodison, S., Carter, B. and Hewitt, J. 2023. The effect of sarcopenia on postoperative outcomes following emergency laparotomy: a systematic review and meta-analysis. The Journal of frailty & aging 12, pp. 305-310. (10.14283/jfa.2023.30)
- Tanos, P. et al. 2023. SHARP risk score: a predictor of poor outcomes in adults admitted for emergency general surgery: a prospective cohort study. Asian Journal of Surgery 46(7), pp. 2668-2674. (10.1016/j.asjsur.2022.10.049)
2022
- Verduri, A. et al. 2022. Comparison between first and second wave of COVID-19 outbreak in older people: the COPE multicentre European observational cohort study. European Journal of Public Health 32(5), pp. 807-812. (10.1093/eurpub/ckac108)
- Carter, B. et al. 2022. The prognostic and discriminatory utility of the Clinical Frailty Scale and modified Frailty Index compared to age. Geriatrics 7(5), article number: e87. (10.3390/geriatrics7050087)
- Braude, P. et al. 2022. Frailty is associated with poor mental health 1 year after hospitalisation with COVID-19. Journal of Affective Disorders 310, pp. 377-383. (10.1016/j.jad.2022.05.035)
- Corrigan, A. E., Carter, B., Smith, A., Pennington, A. and Hewitt, J. 2022. MORe PREcISE: a multicentre prospective study of patient reported outcome measures in stroke morbidity: a cross sectional study. BMC Neurology 22(1), article number: 145. (10.1186/s12883-022-02634-0)
- Holloway, A. et al. 2022. Young Adults Rehabilitation Needs and Experiences following Stroke (YARNS): A review of digital accounts to inform the development of age-appropriate support and rehabilitation. Journal of Advanced Nursing 78(3), pp. 869-882. (10.1111/jan.15076)
- Evans, N. R. et al. 2022. Frailty and cerebrovascular disease: Concepts and clinical implications for stroke medicine. International Journal of Stroke 17(3), pp. 251-259. (10.1177/17474930211034331)
- Carter, B. et al. 2022. Prognostic value of estimated glomerular filtration rate in hospitalised older patients (over 65) with COVID-19: a multicentre, European, observational cohort study. BMC Geriatrics 22(1), article number: 119. (10.1186/s12877-022-02782-5)
2021
- Alghamdi, I., Ariti, C., Williams, A., Wood, E. and Hewitt, J. 2021. Prevalence of fatigue after stroke: a systematic review and meta-analysis. European Stroke Journal 6(4), pp. 319-332. (10.1177/23969873211047681)
- Collins, J. T., Carter, B. and Hewitt, J. 2021. COVID-19 risk and mortality in hospitals: this is not a time to let our guard down. Thorax 76(12), pp. 1174-1175. (10.1136/thoraxjnl-2021-217661)
- Wong, P. Y. et al. 2021. FMALE score: combining practical risk scales to improve preoperative predictive accuracy in emergency general surgery: a multi-centre prospective cohort study. The American Journal of Surgery 222(5), pp. 911-912. (10.1016/j.amjsurg.2021.04.009)
- Hewitt, J., Bains, N., Wallis, K., Gething, S., Pennington, A. and Carter, B. 2021. The use of patient reported outcome measures (PROMs) 6 months post-stroke and their association with the National Institute of Health Stroke Scale (NIHSS) on admission to hospital. Geriatrics 6(3), article number: 88. (10.3390/geriatrics6030088)
- Kastora, S., Kounidas, G., Perrott, S., Carter, B., Hewitt, J. and Myint, P. K. 2021. Clinical frailty scale as a point of care prognostic indicator of mortality in COVID-19: a systematic review and meta-analysis. EClinicalMedicine 36, article number: 100896. (10.1016/j.eclinm.2021.100896)
- Benassi, M. et al. 2021. A single patient reported outcome measure for acquired brain injury, multiple sclerosis & Parkinson's disease. PLoS ONE 16(6), article number: e0251484. (10.1371/journal.pone.0251484)
- Parmar, K. L. et al. 2021. Frailty in older patients undergoing emergency laparotomy. Annals of Surgery 273, pp. 709-718. (10.1097/SLA.0000000000003402)
- Smith, A., Hewitt, J., Quinn, T. J. and Robling, M. 2021. Patient-reported outcome measures (PROMs) use in post-stroke patient care and clinical practice: a realist synthesis protocol. Systematic Reviews 10(1), article number: 128. (10.1186/s13643-021-01682-w)
2020
- Braude, P. et al. 2020. The influence of ACE inhibitors and ARBs on hospital length of stay and survival in people with COVID-19. IJC Heart & Vasculature 31, article number: 100660. (10.1016/j.ijcha.2020.100660)
- Viches-Moraga, A. et al. 2020. Increased care at discharge from COVID-19: The association between pre- admission frailty and increased care needs after hospital discharge; a multi-centre, European observational cohort study. BMC Medicine 18, article number: 408. (10.1186/s12916-020-01856-8)
- Tray, H. S. et al. 2020. Impact of surgery on older patients hospitalized with an acute abdomen: findings from the Older Persons Surgical Outcome Collaborative. Frontiers in Surgery 7, article number: 583653. (10.3389/fsurg.2020.583653)
- Broad, A., Carter, B., Mckelvie, S. and Hewitt, J. 2020. The convergent validity of the electronic Frailty Index (eFI) with the Clinical Frailty Scale (CFS). Geriatrics 5(4), article number: 88. (10.3390/geriatrics5040088)
- Sanyaolu, L., Scholz, A. F. M., Mayo, I., Coode-Bate, J., Carter, B., Quinn, T. and Hewitt, J. 2020. Risk factors for incident delirium among urological patients: a systematic review and meta-analysis with GRADE summary of findings. BMC Urology 20, article number: 169. (10.1186/s12894-020-00743-x)
- Carter, B. et al. 2020. Nosocomial COVID-19 infection: examining the risk of mortality. The COPE-Nosocomial study (COVID in Older PEople).. Journal of Hospital Infection 106(2), pp. 376-384. (10.1016/j.jhin.2020.07.013)
- Price, A. et al. 2020. A study protocol for the COPE study: COVID-19 in Older PEople - the influence of frailty and multimorbidity on survival. A multi-centre, European observational study. BMJ Open 10(9), article number: e040569. (10.1136/bmjopen-2020-040569)
- Bruce, E. et al. 2020. Prior routine use of non-sterioda anti-inflammatory drugs (NSAIDs) and important outcomes in hospitalised patients with COVID-19. Journal of Clinical Medicine 9(8), article number: 2586. (10.3390/jcm9082586)
- Ball, E. L., Owen-Booth, B., Gray, A., Shenkin, S. D., Hewitt, J. and McCleery, J. 2020. Aromatherapy for dementia. Cochrane Database of Systematic Reviews(8), article number: CD003150. (10.1002/14651858.CD003150.pub3)
- Hewitt, J. et al. 2020. The effect of frailty on survival in patients with COVID-19 (COPE): a multicentre, European, observational cohort study. Lancet Public Health 5(8), pp. e444-e451. (10.1016/S2468-2667(20)30146-8)
- Moug, S., Carter, B., Myint, P. K., Hewitt, J., McCarthy, K. and Pearce, L. 2020. Decision-making in COVID-19 and frailty. Geriatrics 5(2), article number: 30. (10.3390/geriatrics5020030)
- Smith, A., Bains, N., Copeland, L., Pennington, A., Carter, B. and Hewitt, J. 2020. Morbidity prevalence estimate at six months following a stroke (MORe PREcISE): protocol for a cohort study. JMIR Research Protocols 9(6), article number: e15851. (10.2196/15851)
- Lewis, S., Evans, L., Rainer, T. and Hewitt, J. 2020. Screening for frailty in older emergency patients and association with outcome. Geriatrics 5(1), article number: 20. (10.3390/geriatrics5010020)
- Carter, B. et al. 2020. Association between preadmission frailty and care level at discharge in older adults undergoing emergency laparotomy. British Journal of Surgery 107(3), pp. 218-226. (10.1002/bjs.11392)
2019
- Hewitt, J. et al. 2019. The prevalence of delirium in an older acute surgical population and its effect on outcome. Geriatrics 4(4), article number: 57. (10.3390/geriatrics4040057)
- Hewitt, J. et al. 2019. A multi-centre, UK-based, non-inferiority randomised controlled trial of 4 follow-up assessment methods in stroke survivors. BMC Medicine 17, article number: 111. (10.1186/s12916-019-1350-5)
- Hewitt, J. et al. 2019. Frailty predicts mortality in all emergency surgical admissions regardless of age. an observational study. Age and Ageing 48(3), pp. 388-394., article number: afy217. (10.1093/ageing/afy217)
- Ablett, A. D. et al. 2019. Anti-cholinergic burden and patient related clinical outcomes in an emergency general surgical setting. Asian Journal of Surgery 42(4), pp. 527-534. (10.1016/j.asjsur.2018.10.005)
2018
- Ablett, A. et al. 2018. A practical risk scale for predicting morbidity and mortality in the emergency general surgical setting: a prospective multi-center study. International Journal of Surgery 60, pp. 236-244. (10.1016/j.ijsu.2018.11.023)
- Ablett, A. D. et al. 2018. Cognitive impairment is associated with mortality in older adults in the emergency surgical setting: Findings from the Older Persons Surgical Outcomes Collaboration (OPSOC): A prospective cohort study. Surgery (10.1016/j.surg.2018.10.013)
- Hewitt, J., Long, S., Carter, B., Bach, S., McCarthy, K. and Clegg, A. 2018. The prevalence of frailty and its association with clinical outcomes in general surgery: a systematic review and meta-analysis. Age and Ageing 47(6), pp. 793-800., article number: afy110. (10.1093/ageing/afy110)
- Hou, C., Xu, Q., Diao, S., Hewitt, J., Li, J. and Carter, B. 2018. Mobile phone applications and self-management of diabetes: a systematic review with meta-analysis, meta-regression of 21 randomized trials, and GRADE. Diabetes, Obesity and Metabolism 20(8), pp. 2009-2013. (10.1111/dom.13307)
- Myint, P. K. et al. 2018. Is anemia associated with cognitive impairment and delirium among older acute surgical patients?. Geriatrics and Gerontology International 18(7), pp. 1025-1030. (10.1111/ggi.13293)
- Smith, A. et al. 2018. Acceptability of the method of administration of a patient-reported outcome measure (PROM) with stroke survivors, a randomised controlled trial protocol. Trials 19(1), article number: 349. (10.1186/s13063-018-2694-4)
- Hewitt, J. et al. 2018. Cognitive impairment in older patients undergoing colorectal surgery. Scottish Medical Journal 63(1), pp. 11-15. (10.1177/0036933017750988)
2017
- Parmar, K. L., Pearce, L., Farrell, I., Hewitt, J. and Moug, S. 2017. Influence of frailty in older patients undergoing emergency laparotomy: a UK-based observational study. BMJ Open 7(10), pp. e017928. (10.1136/bmjopen-2017-017928)
- Oldroyd, C., Scholz, A. F. M., Hinchliffe, R. J., McCarthy, K., Hewitt, J. and Quinn, T. J. 2017. A systematic review and meta-analysis of factors for delirium in vascular surgical patients. Journal of Vascular Surgery 66(4), pp. 1269-1279. (10.1016/j.jvs.2017.04.077)
- Kendall, K. M. et al. 2017. Cognitive performance among carriers of pathogenic copy number variants: analysis of 152,000 UK Biobank subjects. Biological Psychiatry 82(2), pp. P103-110. (10.1016/j.biopsych.2016.08.014)
- Goeteyn, J., Evans, L., De Cleyn, S., Fauconnier, S., Damen, C., Hewitt, J. and Ceelen, W. 2017. Frailty as a predictor of mortality in the elderly emergency general surgery patient. Acta Chirurgica Belgica 117(6), pp. 370-375. (10.1080/00015458.2017.1337339)
- Evans, L. et al. 2017. Preoperative kidney function linked to mortality and readmission outcomes at Day 90 and 30 in older emergency surgical patients. European Geriatric Medicine 8(3), pp. 216-220. (10.1016/j.eurger.2017.03.001)
- Jelley, B., Long, S., Butler, J. and Hewitt, J. 2017. Cohort profile: the Welsh Geriatric Registrar-Led Research Network (WeGeN): rationale, design and description. BMJ Open 7(2), article number: e013031. (10.1136/bmjopen-2016-013031)
2016
- Hou, C., Carter, B. R., Hewitt, J., Francisa, T. and Mayor, S. 2016. Do mobile phone applications improve glycemic control (HbA1c) in the self-management of diabetes? A systematic review, meta-analysis, and GRADE of 14 randomized trials. Diabetes Care 39(11), pp. 2089-2095. (10.2337/dc16-0346)
- McCarthy, K. and Hewitt, J. 2016. The Prevalence and Outcomes of Colorectal Cancer Surgery in the Very Elderly. Clinics in Surgery 1, article number: 1122.
- Myint, P. K. et al. 2016. The prevalence of hyperglycaemia and its relationship with mortality, readmissions and length of stay in an older acute surgical population: a multicentre study. Postgraduate Medical Journal 92(1091), pp. 514-519. (10.1136/postgradmedj-2015-133777)
- Pearce, L., Bunni, J., McCarthy, K. and Hewitt, J. 2016. Surgery in the older person: Training needs for the provision of multidisciplinary care. Annals of the Royal College of Surgeons of England 98(6), pp. 367-370. (10.1308/rcsann.2016.0180)
- Robson, R. et al. 2016. HbA1c measurement and relationship to incident stroke. Diabetic Medicine 33(4), pp. 459-462. (10.1111/dme.13057)
- Sumrien, H., Dadnam, C., Hewitt, J. and McCarthy, K. 2016. Feasibility of Transanal Minimally Invasive Surgery (TAMIS) for Rectal Tumours and Its Impact on Quality of Life ? The Bristol Series. Anticancer Research 36(4), pp. 2005-2010.
- Hewitt, J. et al. 2016. Prevalence of multimorbidity and its association with outcomes in older emergency general surgical patients: an observational study. BMJ Open 6(3), article number: e010126. (10.1136/bmjopen-2015-010126)
- Hewitt, J., Walters, M., Padmanabhan, S. and Dawson, J. 2016. Cohort profile of the UK Biobank: diagnosis and characteristics of cerebrovascular disease. BMJ Open 6(3), article number: e009161. (10.1136/bmjopen-2015-009161)
- Castilla-Guerra, L., Fernández-Moreno, M. C. and Hewitt, J. 2016. Treatment of hyperglycaemia in patients with acute stroke. Revista Clínica Española 216(2), pp. 92-98. (10.1016/j.rce.2015.06.005)
- Khan, A. A., Quinn, T. J., Hewitt, J., Fan, Y. and Dawson, J. 2016. Serum uric acid level and association with cognitive impairment and dementia: systematic review and meta-analysis. AGE 38(1), article number: 16. (10.1007/s11357-016-9871-8)
- Scholz, A., Oldroyd, C., McCarthy, K., Quinn, T. J. and Hewitt, J. 2016. Systematic review and meta-analysis of risk factors for postoperative delirium among older patients undergoing gastrointestinal surgery. British Journal of Surgery 103(2), pp. e21-e28. (10.1002/bjs.10062)
2015
- Cheok, G., Tan, D., Low, A. and Hewitt, J. 2015. Is Nintendo Wii an Effective Intervention for Individuals With Stroke? A Systematic Review and Meta-Analysis. Journal of the American Medical Directors Association 16(11), pp. 923-932. (10.1016/j.jamda.2015.06.010)
- Moug, S. J., McCarthy, K., Coode-Bate, J., Stechman, M. and Hewitt, J. 2015. Laparoscopic versus open surgery for colorectal cancer in the older person: A systematic review. Annals of Medicine and Surgery 4(3), pp. 311-318. (10.1016/j.amsu.2015.08.002)
- Iwere, R. B. and Hewitt, J. 2015. Myopathy in older people receiving statin therapy: a systematic review and meta-analysis. British Journal of Clinical Pharmacology 80(3), pp. 363-371. (10.1111/bcp.12687)
- Hewitt, J., Moug, S. J., Middleton, M., Chakrabarti, M., Stechman, M. J. and McCarthy, K. 2015. Prevalence of frailty and its association with mortality in general surgery. American Journal of Surgery 209(2), pp. 254-259. (10.1016/j.amjsurg.2014.05.022)
- Middleton, M., Stechman, M., Moug, S., McCarthy, K. and Hewitt, J. 2015. Risk prediction tools for older general surgical patients. Reviews in Clinical Gerontology 25(1), pp. 12-21. (10.1017/S0959259815000027)
2014
- Sharp, K. and Hewitt, J. 2014. Dance as an intervention for people with Parkinson's disease: A systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews 47, pp. 445-456. (10.1016/j.neubiorev.2014.09.009)
- Hewitt, J. et al. 2014. The prevalence of cognitive impairment in emergency general surgery. International Journal of Surgery 12(10), pp. 1031-1035. (10.1016/j.ijsu.2014.07.020)
2013
- Dawson, J. et al. 2013. Acetaminophen use and change in blood pressure in a hypertensive population. Journal of Hypertension 31(7), pp. 1485-1490. (10.1097/HJH.0b013e328360f6f8)
- McCarthy, K., Hardy, K., Ackermann, C. and Hewitt, J. 2013. The acute abdomen in the older person. Scottish Medical Journal 58(1), pp. 41-45. (10.1177/0036933012474594)
2012
- Paul, L. et al. 2012. Hematocrit predicts long-term mortality in a nonlinear and sex-specific manner in hypertensive adults. Hypertension 60(3), pp. 631-638. (10.1161/HYPERTENSIONAHA.112.191510)
- McCarthy, K., Pearson, K., Fulton, R. and Hewitt, J. 2012. Pre-operative chemoradiation for non-metastatic locally advanced rectal cancer. Cochrane Database of Systematic Reviews(12), article number: CD008368. (10.1002/14651858.CD008368.pub2)
2011
- Hewitt, J., Smeeth, L., Chaturvedi, N., Bulpitt, C. J. and Fletcher, A. E. 2011. Self management and patient understanding of diabetes in the older person. Diabetic Medicine 28(1), pp. 117-122. (10.1111/j.1464-5491.2010.03142.x)
2009
- Hewitt, J., Smeeth, L., Bulpitt, C. J. and Fletcher, A. E. 2009. The prevalence of Type 2 diabetes and its associated health problems in a community-dwelling elderly population. Diabetic Medicine 26(4), pp. 370-376. (10.1111/j.1464-5491.2009.02687.x)
2005
- Hewitt, J. 2005. Respiratory symptoms in older people and their association with mortality. Thorax 60(4), pp. 331-334. (10.1136/thx.2004.029579)
Articles
- Verduri, A., Clini, E., Carter, B. and Hewitt, J. 2024. Impact of frailty on symptom burden in chronic obstructive pulmonary disease. Journal of Clinical Medicine 13(4), article number: 984. (10.3390/jcm13040984)
- Verduri, A., Carter, B., Laraman, J., Rice, C., Clini, E., Maskell, N. A. and Hewitt, J. 2023. Frailty and its influence on mortality and morbidity in COPD: A systematic review and meta-analysis. Internal and Emergency Medicine 18, pp. 2423-2434. (10.1007/s11739-023-03405-6)
- Masoli, J. A. H. et al. 2023. New horizons in the role of digital data in the healthcare of older people. Age and Ageing 52(8), article number: afad134. (10.1093/ageing/afad134)
- Verduri, A. et al. 2023. Frailty prevalence and association with clinical outcomes in interstitial lung disease, asthma, and pleural disease. Geriatrics 8(4), article number: 82. (10.3390/geriatrics8040082)
- Humphry, N., Jones, M., Goodison, S., Carter, B. and Hewitt, J. 2023. The effect of sarcopenia on postoperative outcomes following emergency laparotomy: a systematic review and meta-analysis. The Journal of frailty & aging 12, pp. 305-310. (10.14283/jfa.2023.30)
- Tanos, P. et al. 2023. SHARP risk score: a predictor of poor outcomes in adults admitted for emergency general surgery: a prospective cohort study. Asian Journal of Surgery 46(7), pp. 2668-2674. (10.1016/j.asjsur.2022.10.049)
- Verduri, A. et al. 2022. Comparison between first and second wave of COVID-19 outbreak in older people: the COPE multicentre European observational cohort study. European Journal of Public Health 32(5), pp. 807-812. (10.1093/eurpub/ckac108)
- Carter, B. et al. 2022. The prognostic and discriminatory utility of the Clinical Frailty Scale and modified Frailty Index compared to age. Geriatrics 7(5), article number: e87. (10.3390/geriatrics7050087)
- Braude, P. et al. 2022. Frailty is associated with poor mental health 1 year after hospitalisation with COVID-19. Journal of Affective Disorders 310, pp. 377-383. (10.1016/j.jad.2022.05.035)
- Corrigan, A. E., Carter, B., Smith, A., Pennington, A. and Hewitt, J. 2022. MORe PREcISE: a multicentre prospective study of patient reported outcome measures in stroke morbidity: a cross sectional study. BMC Neurology 22(1), article number: 145. (10.1186/s12883-022-02634-0)
- Holloway, A. et al. 2022. Young Adults Rehabilitation Needs and Experiences following Stroke (YARNS): A review of digital accounts to inform the development of age-appropriate support and rehabilitation. Journal of Advanced Nursing 78(3), pp. 869-882. (10.1111/jan.15076)
- Evans, N. R. et al. 2022. Frailty and cerebrovascular disease: Concepts and clinical implications for stroke medicine. International Journal of Stroke 17(3), pp. 251-259. (10.1177/17474930211034331)
- Carter, B. et al. 2022. Prognostic value of estimated glomerular filtration rate in hospitalised older patients (over 65) with COVID-19: a multicentre, European, observational cohort study. BMC Geriatrics 22(1), article number: 119. (10.1186/s12877-022-02782-5)
- Alghamdi, I., Ariti, C., Williams, A., Wood, E. and Hewitt, J. 2021. Prevalence of fatigue after stroke: a systematic review and meta-analysis. European Stroke Journal 6(4), pp. 319-332. (10.1177/23969873211047681)
- Collins, J. T., Carter, B. and Hewitt, J. 2021. COVID-19 risk and mortality in hospitals: this is not a time to let our guard down. Thorax 76(12), pp. 1174-1175. (10.1136/thoraxjnl-2021-217661)
- Wong, P. Y. et al. 2021. FMALE score: combining practical risk scales to improve preoperative predictive accuracy in emergency general surgery: a multi-centre prospective cohort study. The American Journal of Surgery 222(5), pp. 911-912. (10.1016/j.amjsurg.2021.04.009)
- Hewitt, J., Bains, N., Wallis, K., Gething, S., Pennington, A. and Carter, B. 2021. The use of patient reported outcome measures (PROMs) 6 months post-stroke and their association with the National Institute of Health Stroke Scale (NIHSS) on admission to hospital. Geriatrics 6(3), article number: 88. (10.3390/geriatrics6030088)
- Kastora, S., Kounidas, G., Perrott, S., Carter, B., Hewitt, J. and Myint, P. K. 2021. Clinical frailty scale as a point of care prognostic indicator of mortality in COVID-19: a systematic review and meta-analysis. EClinicalMedicine 36, article number: 100896. (10.1016/j.eclinm.2021.100896)
- Benassi, M. et al. 2021. A single patient reported outcome measure for acquired brain injury, multiple sclerosis & Parkinson's disease. PLoS ONE 16(6), article number: e0251484. (10.1371/journal.pone.0251484)
- Parmar, K. L. et al. 2021. Frailty in older patients undergoing emergency laparotomy. Annals of Surgery 273, pp. 709-718. (10.1097/SLA.0000000000003402)
- Smith, A., Hewitt, J., Quinn, T. J. and Robling, M. 2021. Patient-reported outcome measures (PROMs) use in post-stroke patient care and clinical practice: a realist synthesis protocol. Systematic Reviews 10(1), article number: 128. (10.1186/s13643-021-01682-w)
- Braude, P. et al. 2020. The influence of ACE inhibitors and ARBs on hospital length of stay and survival in people with COVID-19. IJC Heart & Vasculature 31, article number: 100660. (10.1016/j.ijcha.2020.100660)
- Viches-Moraga, A. et al. 2020. Increased care at discharge from COVID-19: The association between pre- admission frailty and increased care needs after hospital discharge; a multi-centre, European observational cohort study. BMC Medicine 18, article number: 408. (10.1186/s12916-020-01856-8)
- Tray, H. S. et al. 2020. Impact of surgery on older patients hospitalized with an acute abdomen: findings from the Older Persons Surgical Outcome Collaborative. Frontiers in Surgery 7, article number: 583653. (10.3389/fsurg.2020.583653)
- Broad, A., Carter, B., Mckelvie, S. and Hewitt, J. 2020. The convergent validity of the electronic Frailty Index (eFI) with the Clinical Frailty Scale (CFS). Geriatrics 5(4), article number: 88. (10.3390/geriatrics5040088)
- Sanyaolu, L., Scholz, A. F. M., Mayo, I., Coode-Bate, J., Carter, B., Quinn, T. and Hewitt, J. 2020. Risk factors for incident delirium among urological patients: a systematic review and meta-analysis with GRADE summary of findings. BMC Urology 20, article number: 169. (10.1186/s12894-020-00743-x)
- Carter, B. et al. 2020. Nosocomial COVID-19 infection: examining the risk of mortality. The COPE-Nosocomial study (COVID in Older PEople).. Journal of Hospital Infection 106(2), pp. 376-384. (10.1016/j.jhin.2020.07.013)
- Price, A. et al. 2020. A study protocol for the COPE study: COVID-19 in Older PEople - the influence of frailty and multimorbidity on survival. A multi-centre, European observational study. BMJ Open 10(9), article number: e040569. (10.1136/bmjopen-2020-040569)
- Bruce, E. et al. 2020. Prior routine use of non-sterioda anti-inflammatory drugs (NSAIDs) and important outcomes in hospitalised patients with COVID-19. Journal of Clinical Medicine 9(8), article number: 2586. (10.3390/jcm9082586)
- Ball, E. L., Owen-Booth, B., Gray, A., Shenkin, S. D., Hewitt, J. and McCleery, J. 2020. Aromatherapy for dementia. Cochrane Database of Systematic Reviews(8), article number: CD003150. (10.1002/14651858.CD003150.pub3)
- Hewitt, J. et al. 2020. The effect of frailty on survival in patients with COVID-19 (COPE): a multicentre, European, observational cohort study. Lancet Public Health 5(8), pp. e444-e451. (10.1016/S2468-2667(20)30146-8)
- Moug, S., Carter, B., Myint, P. K., Hewitt, J., McCarthy, K. and Pearce, L. 2020. Decision-making in COVID-19 and frailty. Geriatrics 5(2), article number: 30. (10.3390/geriatrics5020030)
- Smith, A., Bains, N., Copeland, L., Pennington, A., Carter, B. and Hewitt, J. 2020. Morbidity prevalence estimate at six months following a stroke (MORe PREcISE): protocol for a cohort study. JMIR Research Protocols 9(6), article number: e15851. (10.2196/15851)
- Lewis, S., Evans, L., Rainer, T. and Hewitt, J. 2020. Screening for frailty in older emergency patients and association with outcome. Geriatrics 5(1), article number: 20. (10.3390/geriatrics5010020)
- Carter, B. et al. 2020. Association between preadmission frailty and care level at discharge in older adults undergoing emergency laparotomy. British Journal of Surgery 107(3), pp. 218-226. (10.1002/bjs.11392)
- Hewitt, J. et al. 2019. The prevalence of delirium in an older acute surgical population and its effect on outcome. Geriatrics 4(4), article number: 57. (10.3390/geriatrics4040057)
- Hewitt, J. et al. 2019. A multi-centre, UK-based, non-inferiority randomised controlled trial of 4 follow-up assessment methods in stroke survivors. BMC Medicine 17, article number: 111. (10.1186/s12916-019-1350-5)
- Hewitt, J. et al. 2019. Frailty predicts mortality in all emergency surgical admissions regardless of age. an observational study. Age and Ageing 48(3), pp. 388-394., article number: afy217. (10.1093/ageing/afy217)
- Ablett, A. D. et al. 2019. Anti-cholinergic burden and patient related clinical outcomes in an emergency general surgical setting. Asian Journal of Surgery 42(4), pp. 527-534. (10.1016/j.asjsur.2018.10.005)
- Ablett, A. et al. 2018. A practical risk scale for predicting morbidity and mortality in the emergency general surgical setting: a prospective multi-center study. International Journal of Surgery 60, pp. 236-244. (10.1016/j.ijsu.2018.11.023)
- Ablett, A. D. et al. 2018. Cognitive impairment is associated with mortality in older adults in the emergency surgical setting: Findings from the Older Persons Surgical Outcomes Collaboration (OPSOC): A prospective cohort study. Surgery (10.1016/j.surg.2018.10.013)
- Hewitt, J., Long, S., Carter, B., Bach, S., McCarthy, K. and Clegg, A. 2018. The prevalence of frailty and its association with clinical outcomes in general surgery: a systematic review and meta-analysis. Age and Ageing 47(6), pp. 793-800., article number: afy110. (10.1093/ageing/afy110)
- Hou, C., Xu, Q., Diao, S., Hewitt, J., Li, J. and Carter, B. 2018. Mobile phone applications and self-management of diabetes: a systematic review with meta-analysis, meta-regression of 21 randomized trials, and GRADE. Diabetes, Obesity and Metabolism 20(8), pp. 2009-2013. (10.1111/dom.13307)
- Myint, P. K. et al. 2018. Is anemia associated with cognitive impairment and delirium among older acute surgical patients?. Geriatrics and Gerontology International 18(7), pp. 1025-1030. (10.1111/ggi.13293)
- Smith, A. et al. 2018. Acceptability of the method of administration of a patient-reported outcome measure (PROM) with stroke survivors, a randomised controlled trial protocol. Trials 19(1), article number: 349. (10.1186/s13063-018-2694-4)
- Hewitt, J. et al. 2018. Cognitive impairment in older patients undergoing colorectal surgery. Scottish Medical Journal 63(1), pp. 11-15. (10.1177/0036933017750988)
- Parmar, K. L., Pearce, L., Farrell, I., Hewitt, J. and Moug, S. 2017. Influence of frailty in older patients undergoing emergency laparotomy: a UK-based observational study. BMJ Open 7(10), pp. e017928. (10.1136/bmjopen-2017-017928)
- Oldroyd, C., Scholz, A. F. M., Hinchliffe, R. J., McCarthy, K., Hewitt, J. and Quinn, T. J. 2017. A systematic review and meta-analysis of factors for delirium in vascular surgical patients. Journal of Vascular Surgery 66(4), pp. 1269-1279. (10.1016/j.jvs.2017.04.077)
- Kendall, K. M. et al. 2017. Cognitive performance among carriers of pathogenic copy number variants: analysis of 152,000 UK Biobank subjects. Biological Psychiatry 82(2), pp. P103-110. (10.1016/j.biopsych.2016.08.014)
- Goeteyn, J., Evans, L., De Cleyn, S., Fauconnier, S., Damen, C., Hewitt, J. and Ceelen, W. 2017. Frailty as a predictor of mortality in the elderly emergency general surgery patient. Acta Chirurgica Belgica 117(6), pp. 370-375. (10.1080/00015458.2017.1337339)
- Evans, L. et al. 2017. Preoperative kidney function linked to mortality and readmission outcomes at Day 90 and 30 in older emergency surgical patients. European Geriatric Medicine 8(3), pp. 216-220. (10.1016/j.eurger.2017.03.001)
- Jelley, B., Long, S., Butler, J. and Hewitt, J. 2017. Cohort profile: the Welsh Geriatric Registrar-Led Research Network (WeGeN): rationale, design and description. BMJ Open 7(2), article number: e013031. (10.1136/bmjopen-2016-013031)
- Hou, C., Carter, B. R., Hewitt, J., Francisa, T. and Mayor, S. 2016. Do mobile phone applications improve glycemic control (HbA1c) in the self-management of diabetes? A systematic review, meta-analysis, and GRADE of 14 randomized trials. Diabetes Care 39(11), pp. 2089-2095. (10.2337/dc16-0346)
- McCarthy, K. and Hewitt, J. 2016. The Prevalence and Outcomes of Colorectal Cancer Surgery in the Very Elderly. Clinics in Surgery 1, article number: 1122.
- Myint, P. K. et al. 2016. The prevalence of hyperglycaemia and its relationship with mortality, readmissions and length of stay in an older acute surgical population: a multicentre study. Postgraduate Medical Journal 92(1091), pp. 514-519. (10.1136/postgradmedj-2015-133777)
- Pearce, L., Bunni, J., McCarthy, K. and Hewitt, J. 2016. Surgery in the older person: Training needs for the provision of multidisciplinary care. Annals of the Royal College of Surgeons of England 98(6), pp. 367-370. (10.1308/rcsann.2016.0180)
- Robson, R. et al. 2016. HbA1c measurement and relationship to incident stroke. Diabetic Medicine 33(4), pp. 459-462. (10.1111/dme.13057)
- Sumrien, H., Dadnam, C., Hewitt, J. and McCarthy, K. 2016. Feasibility of Transanal Minimally Invasive Surgery (TAMIS) for Rectal Tumours and Its Impact on Quality of Life ? The Bristol Series. Anticancer Research 36(4), pp. 2005-2010.
- Hewitt, J. et al. 2016. Prevalence of multimorbidity and its association with outcomes in older emergency general surgical patients: an observational study. BMJ Open 6(3), article number: e010126. (10.1136/bmjopen-2015-010126)
- Hewitt, J., Walters, M., Padmanabhan, S. and Dawson, J. 2016. Cohort profile of the UK Biobank: diagnosis and characteristics of cerebrovascular disease. BMJ Open 6(3), article number: e009161. (10.1136/bmjopen-2015-009161)
- Castilla-Guerra, L., Fernández-Moreno, M. C. and Hewitt, J. 2016. Treatment of hyperglycaemia in patients with acute stroke. Revista Clínica Española 216(2), pp. 92-98. (10.1016/j.rce.2015.06.005)
- Khan, A. A., Quinn, T. J., Hewitt, J., Fan, Y. and Dawson, J. 2016. Serum uric acid level and association with cognitive impairment and dementia: systematic review and meta-analysis. AGE 38(1), article number: 16. (10.1007/s11357-016-9871-8)
- Scholz, A., Oldroyd, C., McCarthy, K., Quinn, T. J. and Hewitt, J. 2016. Systematic review and meta-analysis of risk factors for postoperative delirium among older patients undergoing gastrointestinal surgery. British Journal of Surgery 103(2), pp. e21-e28. (10.1002/bjs.10062)
- Cheok, G., Tan, D., Low, A. and Hewitt, J. 2015. Is Nintendo Wii an Effective Intervention for Individuals With Stroke? A Systematic Review and Meta-Analysis. Journal of the American Medical Directors Association 16(11), pp. 923-932. (10.1016/j.jamda.2015.06.010)
- Moug, S. J., McCarthy, K., Coode-Bate, J., Stechman, M. and Hewitt, J. 2015. Laparoscopic versus open surgery for colorectal cancer in the older person: A systematic review. Annals of Medicine and Surgery 4(3), pp. 311-318. (10.1016/j.amsu.2015.08.002)
- Iwere, R. B. and Hewitt, J. 2015. Myopathy in older people receiving statin therapy: a systematic review and meta-analysis. British Journal of Clinical Pharmacology 80(3), pp. 363-371. (10.1111/bcp.12687)
- Hewitt, J., Moug, S. J., Middleton, M., Chakrabarti, M., Stechman, M. J. and McCarthy, K. 2015. Prevalence of frailty and its association with mortality in general surgery. American Journal of Surgery 209(2), pp. 254-259. (10.1016/j.amjsurg.2014.05.022)
- Middleton, M., Stechman, M., Moug, S., McCarthy, K. and Hewitt, J. 2015. Risk prediction tools for older general surgical patients. Reviews in Clinical Gerontology 25(1), pp. 12-21. (10.1017/S0959259815000027)
- Sharp, K. and Hewitt, J. 2014. Dance as an intervention for people with Parkinson's disease: A systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews 47, pp. 445-456. (10.1016/j.neubiorev.2014.09.009)
- Hewitt, J. et al. 2014. The prevalence of cognitive impairment in emergency general surgery. International Journal of Surgery 12(10), pp. 1031-1035. (10.1016/j.ijsu.2014.07.020)
- Dawson, J. et al. 2013. Acetaminophen use and change in blood pressure in a hypertensive population. Journal of Hypertension 31(7), pp. 1485-1490. (10.1097/HJH.0b013e328360f6f8)
- McCarthy, K., Hardy, K., Ackermann, C. and Hewitt, J. 2013. The acute abdomen in the older person. Scottish Medical Journal 58(1), pp. 41-45. (10.1177/0036933012474594)
- Paul, L. et al. 2012. Hematocrit predicts long-term mortality in a nonlinear and sex-specific manner in hypertensive adults. Hypertension 60(3), pp. 631-638. (10.1161/HYPERTENSIONAHA.112.191510)
- McCarthy, K., Pearson, K., Fulton, R. and Hewitt, J. 2012. Pre-operative chemoradiation for non-metastatic locally advanced rectal cancer. Cochrane Database of Systematic Reviews(12), article number: CD008368. (10.1002/14651858.CD008368.pub2)
- Hewitt, J., Smeeth, L., Chaturvedi, N., Bulpitt, C. J. and Fletcher, A. E. 2011. Self management and patient understanding of diabetes in the older person. Diabetic Medicine 28(1), pp. 117-122. (10.1111/j.1464-5491.2010.03142.x)
- Hewitt, J., Smeeth, L., Bulpitt, C. J. and Fletcher, A. E. 2009. The prevalence of Type 2 diabetes and its associated health problems in a community-dwelling elderly population. Diabetic Medicine 26(4), pp. 370-376. (10.1111/j.1464-5491.2009.02687.x)
- Hewitt, J. 2005. Respiratory symptoms in older people and their association with mortality. Thorax 60(4), pp. 331-334. (10.1136/thx.2004.029579)
Biography
Education and qualifications
PhD, Epdemiology, London School of Hygeine and Tropical Medicine, 2005
MSc, Epidmiology, London School of Hygeine and Tropical Medicine, 2002
MBBS, University of London, 1994
Professional memberships
Fellow of the Royal College of Physicians and Surgeons, Glasgow
NIHR Lead for Stroke Research In Wales
Academic positions
2012-13, Honorary Consultant Physician, University of Glasgow
2007-12, Consultant Physician Portsmouth NHS Trust
2001-2005, NHS Research and Development Fellow, London School of Hygeine and Tropical Medicine
Committees and reviewing
Chair, School of Medicine Ethics Commitee 2015-present, member since 2014.
External
Member of the MRC Ethics, Regulation and Public Involvement Committee (ERPIC), since 2016
Member of the Research Commitee for the British Geraitric Society, since 2016
Vice Chair and Chair of the Brisith Geriatric Society (Wales), 2014-2019
Vice Chiar, Ethics and Governance Council of the UK Biobank 2014-16
Member, Ethics and Governance Coucil of the UK Biobank, 2007-14
Member of the Research Commitee for the Britsih Association of Stroke Physicians, since 2016
BGS representative of the Joint Stroke Working Group of the Royal College of Physicians of London, since 2018
Associate Editor: Age and Ageing, Geriatrics
Supervisions
Current PhD Students
Alex Smith, Patient Reported Outcome Mesures in Stroke; The Stroke Association
Julia Marshall, Affect on Carers of Stroke DIsease; Welsh Government
Stephanie Gething, Compliance in Patient Reported Outcome Measures in Stroke; THrombosis Fund Neville Hall Hospital
Anna Pennington, Exercise Innterventions after a Stroke; Self Funding
Engagement
Chair School of Medicine Ethics Commitee 2015-present (member since 2013)
