Kate Bresner
Senior Technician (Genome Hub)
- bresnercm@cardiff.ac.uk
- +44 (0)29 2068 8362
- Sir Martin Evans Building, Museum Avenue, Cardiff, CF10 3AX
Overview
I have worked at Cardiff University since 2010. Within my current role I am responsible for the generation of high-quality Next-Generation sequencing data for a diverse range of projects from biomedicine to ecology.
My previous role was Research Manager for the Alzheimer's Research Group, I was responsible for the operation of the Alzheimer’s Disease Genetics Team, planning, organising and delivering projects both within the University and in collaboration with world-renowned scientists. I was also responsible for a large part of research funding and grant management and provided professional advice and guidance on research sample management and Human Tissue Act compliance processes and procedures.
Prior to my management role, I was primarily laboratory based, as member of a core facility, and led a several laboratory research projects for the Parkinson's Research Team.
I am a member of the Institute of Science and Technology and have been awarded professional registration (RSci) by the Science Council.
Biography
2020 - present: Senior Technician (Genome Research Hub), School of Biosciences.
The Genomics Research Hub acts as a focus and provides support for a community of genomics researchers, with particular expertise in metagenomics, de novo genome assembly, transcriptome analysis, chromatin mapping and epigenetics
We utilise linked technology platforms that support user-driven, next-generation sequencing for a wide-range of users and applications including:
- small genome assembly
- genome re-sequencing
- metagenomics
- RNA-seq
- ChIP-seq
- chromatin-seq.
We also help researchers develop novel genomics methods when required.
2010 - 2020: Cardiff University School of Medicine, Division of Psychological Medicine & Clinical Neurosciences
2019 - 2020: Research Manager, Alzheimer's Research Group
2018 - 2019: Sample Co-Ordinator, Alzheimer's Research Group
2012 - 2018: Senior Research Technician, Parkinson's Research Group
2010 - 2012: Research Technician, Core Facility
Honours and awards
Registered Scientist (RSci), awarded by Science Council (2018)
Professional memberships
Member of the Institute of Science and Technology
Publications
2020
- Tan, M. M.et al. 2020. Genome-wide association studies of cognitive and motor progression in Parkinson's disease. Movement Disorders (10.1002/mds.28342)
2019
- Tan, M. M.et al. 2019. Genetic analysis of Mendelian mutations in a large UK population-based Parkinson's disease study. Brain 142(9), pp. 2828-2844. (10.1093/brain/awz191)
2018
- Malek, N.et al. 2018. Features of GBA-associated Parkinson's disease at presentation in the UK Tracking Parkinson's study. Journal of Neurology, Neurosurgery and Psychiatry 89(7), pp. 702-709. (10.1136/jnnp-2017-317348)
2016
- Malek, N.et al. 2016. Olfaction in Parkin single and compound heterozygotes in a cohort of young onset Parkinson's disease patients. Acta Neurologica Scandinavica 134(4), pp. 271-276. (10.1111/ane.12538)
2015
- Malek, N.et al. 2015. Tracking Parkinson's: study design and baseline patient data. Journal of Parkinson's Disease 5(4), pp. 947-959. (10.3233/JPD-150662)
I have recently taken a role within the Genome Hub at Cardiff School of Biosciences, generating Next-Generation sequencing data for a diverse range of projects from biomedicine to ecology.
As Research Manager with the Alzheimer's Disease Research Group I was involved in many projects related to Alzheimer's and Dementia research, both within Cardiff University and also large international collaborations.
Prior to my management role, my research projects investigated the genetic basis of Parkinson's disease, where I used a diverse range of complex techniques in order to generate high quality biological data which is then used for statistical analysis.