Professor Antony Bayer
Emeritus Professor
- bayer@cardiff.ac.uk
- Routledge Academic Centre, University Hospital Llandough, Penarth, Cardiff, CF64 2XX
Overview
My clinical and research interests focus on epidemiology, assessment and clinical management of cognitive disorders and neurodegenerative disease, especially Alzheimer's disease. I have particular interest in clinical trials of new pharmacological and nonpharmacological treatments for dementia and organisation of services. Other active research areas include ethical issues and ageing, the concept of frailty and multimorbidity. I am the Director of the Memory Assessment Service in Cardiff and Vale University Health Board and a member of numerous national and international bodies concerned with ageing and older people, including the Public Health Committee and Research Grants Advisory Board of the Alzheimer’s Society, the Abbeyfield Research Foundation, the Expert Centre of the International Federation of Aging, the IAG Global Ageing Research Network and EASD Global Initiative on Diabetes in Older People.
Biography
Publications
2022
- Creavin, S., Fish, M., Bayer, A., Gallacher, J. and Ben-Shlomo, Y. 2022. Decline in cognition from mid-life improves specificity of mini-mental state examination: diagnostic test accuracy in Caerphilly Prospective Study (CaPs). Journal of Alzheimer's Disease 89(4), pp. 1241-1248. (10.3233/JAD-220345)
- Gallacher, J. et al. 2022. Amateur Boxing and Dementia: Cognitive Impairment Within the 35-Year Caerphilly Cohort Study. Clinical Journal of Sport Medicine 32(3), pp. 329-333. (10.1097/JSM.0000000000000976)
- Bellenguez, C. et al. 2022. New insights into the genetic etiology of Alzheimer's disease and related dementias. Nature Genetics 54(4), pp. 412-436. (10.1038/s41588-022-01024-z)
2021
- Creavin, S. T., Haworth, J., Fish, M., Cullum, S., Bayer, A., Purdy, S. and Ben-Shlomo, Y. 2021. Clinical judgment of GPs for the diagnosis of dementia: a diagnostic test accuracy study. British Journal of General Practice Open 5(5), article number: 58. (10.3399/BJGPO.2021.0058)
- Collins, J. T., Mohamed, B. and Bayer, A. 2021. Feasibility of remote Memory Clinics using the plan, do, study, act (PDSA) cycle. Age and Ageing 50(6), pp. 2259–2263. (10.1093/ageing/afab173)
- Richards, E., Tales, A., Bayer, A., Norris, J. E., Hanley, C. J. and Thornton, I. M. 2021. Reaction time decomposition as a tool to study subcortical ischemic vascular cognitive impairment. Journal of Alzheimer's Disease Reports 5(1), pp. 625-636. (10.3233/ADR-210029)
- Richards, E., Thornton, I. M., Bayer, A. and Tales, A. 2021. Inhibitory control deficits in vascular cognitive impairment revealed using the MILO task. Neuropsychologia 155, article number: 107794. (10.1016/j.neuropsychologia.2021.107794)
- Butler, C. C. et al. 2021. Probiotics to reduce antibiotic administration in care home residents aged 65 years and older: the PRINCESS RCT. Efficacy and Mechanism Evaluation 8(7) (10.3310/eme08070)
2020
- Bayer, A. 2020. Next steps after diagnosing dementia: interventions to help patients and families. Practical Neurology 20(4), pp. 294-303. (10.1136/practneurol-2019-002416)
- Elwood, P. C. et al. 2020. Better than any pill - and no side effects! Healthy lifestyles, statins and aspirin. Lifestyle Medecine 1(1), article number: e4. (10.1002/lim2.4)
- Butler, C. C. et al. 2020. Effect of probiotic use on antibiotic administration among care home residents: a randomized clinical trial. Journal of the American Medical Association 324(1), pp. 47 - 56. (10.1001/jama.2020.8556)
- Revie, L., Bayer, A., Teufel, C. and Metzler-Baddeley, C. 2020. A review of the perceptual and attentional-executive characteristics of dementia with Lewy bodies relative to Alzheimer's and Parkinson's disease. PsyArXiv
2019
- Bayer, A. 2019. Subcortical ischaemic vascular cognitive impairment: insights from reaction measures. Journal of Alzheimer's Disease 72(3), pp. 845-857. (10.3233/JAD-190889)
- Richards, E., Bayer, A., Hanley, C., Norris, J. E., Tree, J. J. and Tales, A. 2019. Reaction time and visible white matter lesions in subcortical ischemic vascular cognitive impairment. Journal of Alzheimer's Disease 72(3), pp. 859-865. (10.3233/JAD-190823)
- Owen-Jones, E. et al. 2019. Protocol for a double-blind placebo-controlled trial to evaluate the efficacy of probiotics in reducing antibiotics for infection in care home residents: the Probiotics to Reduce Infections iN CarE home reSidentS (PRINCESS) trial. BMJ Open 9(6), article number: e027513. (10.1136/bmjopen-2018-027513)
- Clare, L. et al. 2019. Individual goal-oriented cognitive rehabilitation to improve everyday functioning for people with early-stage dementia: a multi-centre randomised controlled trial (the GREAT trial). International Journal of Geriatric Psychiatry 34(5), pp. 709-721. (10.1002/gps.5076)
- Koelewijn, L. et al. 2019. Oscillatory hyperactivity and hyperconnectivity in young APOE-ɛ4 carriers and hypoconnectivity in Alzheimer's disease. eLife 8, article number: e36011. (10.7554/eLife.36011)
- Kunkle, B. W. et al. 2019. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics 51(3), pp. 414-430. (10.1038/s41588-019-0358-2)
- Clare, L. et al. 2019. Goal-oriented cognitive rehabilitation for early-stage Alzheimer's and related dementias: the GREAT RCT. Health Technology Assessment 23(10) (10.3310/hta23100)
2018
- Bayer, A. J. 2018. The role of biomarkers and imaging in the clinical diagnosis of dementia. Age and Ageing 47(5), pp. 641-643. (10.1093/ageing/afy004)
- Anttila, V. et al. 2018. Analysis of shared heritability in common disorders of the brain. Science 360(6395), article number: eaap8757. (10.1126/science.aap8757)
- Sims, R. et al. 2018. Meta-analysis of genetic association with diagnosed Alzheimer's disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing. [Online]. bioRxiv. (10.1101/294629) Available at: https://doi.org/10.1101/294629
- Patterson, C. C. et al. 2018. Troponin and BNP are markers for subsequent non-ischaemic congestive heart failure: the Caerphilly Prospective Study (CaPS). Open Heart 5(1), article number: e000692. (10.1136/openhrt-2017-000692)
- Elwood, P. et al. 2018. Healthy living and cancer: evidence from UK Biobank. ecancermedicalscience 12, article number: 792. (10.3332/ecancer.2018.792)
2017
- Bunn, F. et al. 2017. Managing diabetes in people with dementia: a realist review. Health Technology Assessment 21(75), pp. 1-133. (10.3310/hta21750)
- Koelewijn, L., Bompas, A., Tales, A., Brookes, M. J., Muthukumaraswamy, S. D., Bayer, A. and Singh, K. D. 2017. Alzheimer's disease disrupts alpha and beta-band resting-state oscillatory network connectivity. Clinical Neurophysiology 128(11), pp. 2347-2357. (10.1016/j.clinph.2017.04.018)
- Torrens-Burton, A., Basoudan, N., Bayer, A. and Tales, A. 2017. Perception and reality of cognitive function: information processing speed, perceived memory function, and perceived task difficulty in older adults. Journal of Alzheimer's Disease 60(4), pp. 1601-1609. (10.3233/JAD-170599)
- Porter, G., Wattam-Bell, J., Bayer, A., Haworth, J., Braddick, O., Atkinson, J. and Tales, A. 2017. Different trajectories of decline for global form and global motion processing in aging, mild cognitive impairment and Alzheimer's disease. Neurobiology of Aging 56, pp. 17-24. (10.1016/j.neurobiolaging.2017.03.004)
- Bunn, F. et al. 2017. What works for whom in the management of diabetes in people living with dementia: a realist review. BMC Medicine 15(141) (10.1186/s12916-017-0909-2)
- Poulos, C. J. et al. 2017. A comprehensive approach to reablement in dementia. Alzheimer's & Dementia: Translational Research & Clinical Interventions 3(3), pp. 450-458. (10.1016/j.trci.2017.06.005)
- Moreno-Arino, M. and Bayer, A. J. 2017. Munchausen syndrome by proxy - illness fabricated by another in older people. Age and Ageing 46(2), pp. 166-167. (10.1093/ageing/afw217)
2016
- Creavin, S. T. et al. 2016. Erratum to: Towards improving diagnosis of memory loss in general practice: TIMeLi diagnostic test accuracy study protocol. BMC Family Practice 17(1) (10.1186/s12875-016-0510-3)
- Creavin, S. T. et al. 2016. Towards improving diagnosis of memory loss in general practice: TIMeLi diagnostic test accuracy study protocol. BMC Family Practice 17(1) (10.1186/s12875-016-0475-2)
- Bunn, F. et al. 2016. Managing diabetes in people with dementia: protocol for a realist review. Systematic Reviews 5, article number: 5. (10.1186/s13643-015-0182-4)
2015
- Patterson, C. C. et al. 2015. Which biomarkers are predictive specifically for cardiovascular or for non-cardiovascular mortality in men? Evidence from the Caerphilly Prospective Study (CaPS). International Journal of Cardiology 201, pp. 113-118. (10.1016/j.ijcard.2015.07.106)
- Jenkins, A. et al. 2015. Are we ready? The construct of subjective cognitive impairment and its utilization in clinical practice: a preliminary UK-based service evaluation. Journal of Alzheimer's Disease 48(s1), pp. S25-S31. (10.3233/JAD-150541)
- Tales, A., Jessen, F., Butler, C., Wilcock, G., Phillips, J., Bayer, A. and Tales, A. 2015. Subjective Cognitive Decline. Journal of Alzheimer's Disease 48(s1), pp. S1-S3. (10.3233/JAD-150719)
- Gillespie, D. et al. 2015. Antibiotic prescribing and associated diarrhoea: a prospective cohort study of care home residents. Age and Ageing 44(5), pp. 853-860. (10.1093/ageing/afv072)
- Harbi, Z., Hicks, Y. A., Setchi, R. and Bayer, A. J. 2015. Segmentation of clock drawings based on spatial and temporal features. Procedia Computer Science 60, pp. 1640-1648. (10.1016/j.procs.2015.08.274)
- Creavin, S., Fish, M., Gallacher, J., Bayer, A. and Ben-Shlomo, Y. 2015. Clinical history for diagnosis of dementia in men: Caerphilly Prospective Study. British Journal of General Practice 65(637), pp. e489-e499. (10.3399/bjgp15X686053)
- Jones, L. et al. 2015. Convergent genetic and expression data implicate immunity in Alzheimer's disease. Alzheimer's and Dementia 11(6), pp. 658-671. (10.1016/j.jalz.2014.05.1757)
2014
- Sinclair, A. J., Hillson, R. and Bayer, A. J. 2014. Diabetes and dementia in older people: a Best Clinical Practice Statement by a multidisciplinary National Expert Working Group. Diabetic Medicine 31(9), pp. 1024-1031. (10.1111/dme.12467)
- Tales, A., Wilcock, G. K., Phillips, J. E. and Bayer, A. J. 2014. Is there more to subjective cognitive impairment than meets the eye? A perspective. Journal of Alzheimer's Disease 41(3), pp. 655-661. (10.3233/JAD-132414)
- Green, C. J., Holly, J. M. P., Bayer, A. J., Fish, M., Ebrahim, S., Gallacher, J. and Ben-Shlomo, Y. 2014. The role of IGF-I, IGF-II, and IGFBP-3 in male cognitive aging and dementia risk: the Caerphilly Prospective Study. Journal of Alzheimer's Disease 41(3), pp. 867-875. (10.3233/JAD-132183)
- Tales, A., Wilcock, G. K., Phillips, J. E. and Bayer, A. J. 2014. Is there more to subjective cognitive impairment than meets the eye? Raising awareness. Journal of Alzheimer's Disease 41(3), pp. 665-666. (10.3233/JAD-141294)
- Escott-Price, V. et al. 2014. Gene-wide analysis detects two new susceptibility genes for Alzheimer's Disease. PLoS ONE 9(6), article number: e94661. (10.1371/journal.pone.0094661)
- Bayer, A., Phillips, M., Porter, G., Leonards, U., Bompas, A. and Tales, A. 2014. Abnormal inhibition of return in mild cognitive impairment: is it specific to the presence of prodromal dementia?. Journal of Alzheimer's Disease 40(1), pp. 177-189. (10.3233/JAD-131934)
- Rodríguez-Mañas, L. et al. 2014. An evaluation of the effectiveness of a multi-modal intervention in frail and pre-frail older people with type 2 diabetes - the MID-Frail study: study protocol for a randomised controlled trial. Trials 15, article number: 34. (10.1186/1745-6215-15-34)
- Bennasar, M., Setchi, R., Hicks, Y. and Bayer, A. J. 2014. Cascade classification for diagnosing dementia. Presented at: 2014 IEEE International Conference on Systems, Man and Cybernetics (SMC), San Diego, CA, USA, 5-8 October 20142014 IEEE International Conference on Systems, Man and Cybernetics (SMC). pp. 2535-2540., (10.1109/SMC.2014.6974308)
2013
- Elwood, P. C. et al. 2013. Healthy lifestyles reduce the incidence of chronic diseases and dementia: evidence from the Caerphilly Cohort Study. PLoS ONE 8(12), article number: e81877. (10.1371/journal.pone.0081877)
- Lambert, J. et al. 2013. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease [Letter]. Nature Genetics 45(12), pp. 1452-1458. (10.1038/ng.2802)
- Bennasar, M., Setchi, R., Bayer, A. J. and Hicks, Y. A. 2013. Feature selection based on information theory in the clock drawing test. Presented at: 17th International Conference on Knowledge-Based and Intelligent Information & Engineering Systems, Kitakyushu, Japan, 9 -12 September 2013Procedia Computer Science, Vol. 22. pp. 902-911., (10.1016/j.procs.2013.09.173)
- Todorov, D., Setchi, R. and Bayer, A. J. 2013. Linguistic markers in the sentence writing question of the mini-mental state examination for discrimination between Alzheimer's and Vascular Dementia. Presented at: 17th International Conference on Knowledge-Based and Intelligent Information & Engineering Systems, Kitakyushu, Japan, 9 -12 September 201317th International Conference on Knowledge-Based and Intelligent Information & Engineering Systems: General Track Proceedings. pp. 114-123.
- Hillman, A., Tadd, W., Calnan, S., Calnan, M., Bayer, A. J. and Read, S. M. 2013. Risk, governance and the experience of care. Sociology of Health and Illness 35(6), pp. 939-955. (10.1111/1467-9566.12017)
- Calnan, M., Tadd, W., Calnan, S., Hillman, A., Read, S. M. and Bayer, A. J. 2013. 'I often worry about the older person being in that system': exploring the key influences on the provision of dignified care for older people in acute hospitals. Ageing and Society 33(3), pp. 465-485. (10.1017/S0144686X12000025)
- Sinclair, A. J., Gadsby, R., Hilson, R., Forbes, A. and Bayer, A. 2013. Brief report: Use of the Mini-Cog as a screening tool for cognitive impairment in diabetes in primary care. Diabetes Research and Clinical Practice 100(1), pp. e23-e25. (10.1016/j.diabres.2013.01.001)
2012
- Birnie, K. et al. 2012. Childhood milk consumption is associated with better physical performance in old age. Age and Ageing 41(6), pp. 776-784. (10.1093/ageing/afs052)
- Gallacher, J. E., Ilubaera, V., Ben-Shlomo, Y., Bayer, A. J., Fish, M., Babisch, W. and Elwood, P. C. 2012. Auditory threshold, phonologic demand, and incident dementia. Neurology 79(15), pp. 1583-1590. (10.1212/WNL.0b013e31826e263d)
- Gallacher, J. E., Elwood, P. C., Pickering, J. E., Bayer, A. J., Fish, M. and Ben-Shlomo, Y. 2012. Benzodiazepine use and risk of dementia: evidence from the Caerphilly Prospective Study (CaPS). Journal of Epidemiology and Community Health 66(10), pp. 869-873. (10.1136/jech-2011-200314)
- Porter, G., Leonards, U., Troscianko, T., Haworth, J., Bayer, A. J. and Tales, A. 2012. Dealing with illumination in visual scenes: effects of ageing and Alzheimer's Disease. PLoS ONE 7(9), article number: e45104. (10.1371/journal.pone.0045104)
- Morgan, G. S., Gallacher, J. E., Bayer, A. J., Fish, M., Ebrahim, S. and Ben-Shlomo, Y. 2012. Physical activity in middle-age and dementia in later life: findings from a prospective cohort of men in Caerphilly, South Wales and a meta-analysis. Journal of Alzheimer's Disease 31(3), pp. 569-580. (10.3233/JAD-2012-112171)
- Sinclair, A. et al. 2012. Diabetes mellitus in older people: position statement on behalf of the International Association of Gerontology and Geriatrics (IAGG), the European Diabetes Working Party for Older People (EDWPOP), and the International Task Force of Experts in Diabetes. Journal of the American Medical Directors Association 13(6), pp. 497-502. (10.1016/j.jamda.2012.04.012)
- Eeles, E., White, S. V., O'Mahony, S. M., Bayer, A. J. and Hubbard, R. E. 2012. The impact of frailty and delirium on mortality in older inpatients. Age and Ageing 41(3), pp. 412-416. (10.1093/ageing/afs021)
- Tales, A., Bayer, A. J., Krajčík, ?. and Jellinger, K. A. 2012. Mild cognitive impairment: beyond memory dysfunction. International Journal of Alzheimer's Disease 2012, article number: 262305. (10.1155/2012/262305)
- Tadd, W., Hillman, A. E., Calnan, M., Calnan, S., Read, S. M. and Bayer, A. J. 2012. From right place - wrong person, to right place - right person: Dignified care for older people. Journal of Health Services Research and Policy 17(Supp 2), pp. 30-36. (10.1258/jhsrp.2011.011118)
- Creavin, S. T. et al. 2012. High caloric intake, poor cognition and dementia: the Caerphilly Prospective Study. European Journal of Epidemiology 27(3), pp. 197-203. (10.1007/s10654-012-9667-9)
- Birnie, K. et al. 2012. Associations of insulin and insulin-like growth factors with physical performance in old age in the Boyd Orr and Caerphilly studies. PLoS ONE 7(1), pp. e30096. (10.1371/journal.pone.0030096)
- Creavin, S. T., Gallacher, J. E., Bayer, A. J., Fish, M., Ebrahim, S. and Ben-Shlomo, Y. 2012. Metabolic syndrome, diabetes, poor cognition, and dementia in the Caerphilly Prospective Study. Journal of Alzheimer's Disease 28(4), pp. 931-939. (10.3233/JAD-2011-111550)
- Tales, A. et al. 2012. Intra-individual reaction time variability in aMCI: A precursor to dementia?. Journal of Alzheimer's Disease 32(2), pp. 457-466. (10.3233/JAD-2012-120505)
- Tadd, W. et al. 2012. PEACH: Promoting Excellence in All Care Homes. Project Report. [Online]. London: Prevention of Abuse and Neglect in the Institutional Care of Older Adults. Available at: https://www.cfmhas.org.uk/research/completed-projects/new-research-page/
2011
- Gardner, M. P. et al. 2011. Diurnal cortisol patterns are associated with physical performance in the Caerphilly Prospective Study. International Journal of Epidemiology 40(6), pp. 1693-1702. (10.1093/ije/dyr113)
- Tadd, W., Hillman, A., Calnan, S., Calnan, M., Bayer, A. J. and Read, S. M. 2011. Right place - wrong person: dignity in the acute care of older people. Quality in Ageing and Older Adults 12(1), pp. 33-43. (10.5042/qiaoa.2011.0143)
- Tales, A., Snowden, R. J., Phillips, M., Haworth, J., Porter, G., Wilcock, G. and Bayer, A. J. 2011. Exogenous phasic alerting and spatial orienting in mild cognitive impairment compared to healthy ageing: study outcome is related to target response. Cortex 47(2), pp. 180-190. (10.1016/j.cortex.2009.09.007)
- Tales, A., Bayer, A., Haworth, J., Snowden, R. J., Phillips, M. and Wilcock, G. 2011. Visual search in mild cognitive impairment: A longitudinal study. Journal of Alzheimer's Disease 24(1), pp. 151-160. (10.3233/JAD-2010-101818)
- Birnie, K. et al. 2011. Childhood socioeconomic position and objectively measured physical capability levels in adulthood: a systematic review and meta-analysis. PLoS ONE 6(1), article number: e15564. (10.1371/journal.pone.0015564)
- Tadd, W., Hillman, A., Calnan, S., Calnan, M., Bayer, A. J. and Read, S. M. 2011. Dignity in practice: An exploration of the care of older adults in acute NHS Trusts. Project Report. [Online]. HMSO. Available at: http://www.bgs.org.uk/pdf_cms/reference/Tadd_Dignity_in_Practice.pdf
- Elwood, P. C., Bayer, A. J., Fish, M., Pickering, J. E., Mitchell, C. P. and Gallacher, J. E. 2011. Sleep disturbance and daytime sleepiness predict vascular dementia. Journal of Epidemiology & Community Health 65(9), pp. 820-824. (10.1136/jech.2009.100503)
- Birnie, K., Martin, R. M., Gallacher, J. E., Bayer, A. J., Gunnell, D., Ebrahim, S. and Ben-Shlomo, Y. 2011. Socio-economic disadvantage from childhood to adulthood and locomotor function in old age: a lifecourse analysis of the Boyd Orr and Caerphilly prospective studies. Journal of Epidemiology & Community Health 65(11), pp. 1014-1023. (10.1136/jech.2009.103648)
- Gardner, M., Smith, G. D., Lightman, S., Gallacher, J. E., Kuh, D., Ebrahim, S. and Bayer, A. J. 2011. Testosterone, cortisol: testosterone ratio and physical performance in later life: results from the caerphilly prospective study (CAPS) [Abstract]. Journal of Epidemiology & Community Health 65(S1), pp. A186., article number: P1-429. (10.1136/jech.2011.142976g.19)
- Birnie, K., Ben-Shlomo, Y., Gunnell, D., Ebrahim, S., Bayer, A. J., Gallacher, J. E. and Martin, R. M. 2011. Diet in childhood and adulthood and physical performance in old age: findings from the Boyd Orr and Caerphilly cohorts [Abstract]. Journal of Epidemiology and Community Health 65(Supp 2), pp. A34-A35.
2010
- Birnie, K. et al. 2010. Insulin-like growth factors and physical performance in old age: The Boyd Orr and Caerphilly studies [Abstract]. Gerontologist 50(S1), pp. 500-500. (10.1093/geront/gnq115)
- Eeles, E., Hubbard, R. E., White, S. V., O'Mahony, M. S., Savva, G. M. and Bayer, A. J. 2010. Hospital use, institutionalisation and mortality associated with delirium. Age and Ageing 39(4), pp. 470-475. (10.1093/ageing/afq052)
- Gallacher, J. E. et al. 2010. Is Sticky blood bad for the brain?: Hemostatic and inflammatory systems and dementia in the Caerphilly Prospective Study. Arteriosclerosis Thrombosis and Vascular Biology 30(3), pp. 599-604. (10.1161/ATVBAHA.109.197368)
- Sinclair, A. J., Armes, D. G., Randhawa, G. and Bayer, A. J. 2010. Caring for older adults with diabetes mellitus: characteristics of carers and their prime roles and responsibilities. Diabetic Medicine 27(9), pp. 1055-1059. (10.1111/j.1464-5491.2010.03066.x)
2009
- Gallacher, J. E. et al. 2009. Does anxiety affect risk of dementia? Findings from the Caerphilly Prospective Study. Psychosomatic Medicine 71(6), pp. 659-666. (10.1097/PSY.0b013e3181a6177c)
- Gallacher, J. E., Bayer, A. J., Dunstan, F. D. J., Yarnell, J., Elwood, P. C. and Ben-Shlomo, Y. 2009. Can we understand why cognitive function predicts mortality? Results from the Caerphilly Prospective Study (CaPS). Intelligence 37(6), pp. 535-544. (10.1016/j.intell.2009.02.004)
- Eeles, E., White, S. V. and Bayer, A. J. 2009. Inability to complete cognitive assessment is a marker of adverse risk [Letter]. Age and Ageing 38(5), pp. 633-634. (10.1093/ageing/afp115)
2008
- Holmes, C. et al. 2008. Long-term effects of Aβ42 immunisation in Alzheimer's disease: Follow-up of a randomised, placebo-controlled phase I trial. The Lancet 372(9634), pp. 216-223. (10.1016/S0140-6736(08)61075-2)
- Sinclair, A. J., Conroy, S. P. and Bayer, A. J. 2008. Impact of diabetes on physical function in older people. Diabetes Care 31(2), pp. 233-235. (10.2337/dc07-1784)
- Mas, M., Renom, A., Vazquez, O., Miralles, R., Bayer, A. J. and Cervera, A. M. 2008. Interruptions to rehabilitation in a geriatric rehabilitation unit: associated factors and consequences [Letter]. Age and Ageing 38(3), pp. 346-349. (10.1093/ageing/afp010)
2007
- Jones, R. W., Bayer, A. J., Inglis, F., Barker, A. and Phul, R. 2007. Safety and tolerability of once-daily versus twice-daily memantine: a randomised, double-blind study in moderate to severe Alzheimer's disease. International Journal of Geriatric Psychiatry 22(3), pp. 258-262. (10.1002/gps.1752)
- White, S. V., Eeles, E., O'Mahony, M. S. and Bayer, A. J. 2007. Delirium and C-reactive protein [Letter]. Age and Ageing 37(1), pp. 123-124. (10.1093/ageing/afm178)
2006
- Nicoll, J. A. R. et al. 2006. Abeta species removal after abeta42 immunization. Journal of Neuropathology and Experimental Neurology 65(11), pp. 1040-1048. (10.1097/01.jnen.0000240466.10758.ce)
- Handley, O. J., Morrison, C. M., Miles, C. and Bayer, A. J. 2006. ApoE gene and familial risk of Alzheimer's disease as predictors of odour identification in older adults. Neurobiology of Aging 27(10), pp. 1425-1430. (10.1016/j.neurobiolaging.2005.08.001)
- Bayer, A. J. 2006. Death with dementia—the need for better care [Editorial]. Age and Ageing 35(2), pp. 101-102. (10.1093/ageing/afj033)
2005
- White, S. V., Calver, B. L., Newsway, V., Wade, R., Patel, S., Bayer, A. J. and O'Mahony, M. S. 2005. Enzymes of drug metabolism during delirium. Age and Ageing 34(6), pp. 603-608. (10.1093/ageing/afi189)
- Gallacher, J. E., Bayer, A. J. and Ben-Shlomo, Y. 2005. Commentary: Activity each day keeps dementia away—does social interaction really preserve cognitive function?. International Journal of Epidemiology 34(4), pp. 872-873. (10.1093/ije/dyi107)
- Sinclair, A. J., Conroy, S. P., Davies, M. and Bayer, A. J. 2005. Post-discharge home-based support for older cardiac patients: a randomised controlled trial. Age and Ageing 34(4), pp. 338-343. (10.1093/ageing/afi116)
- Bayer, A. J., Bullock, R., Jones, R. W., Paterson, K. R., Jenkins, L., Millais, S. B. and Donoghue, S. 2005. Evaluation of the safety and immunogenicity of synthetic Aβ42 (AN1792) in patients with AD. Neurology 64(1), pp. 94-101. (10.1212/01.WNL.0000148604.77591.67)
- Gallacher, J. E., Pickering, J., Elwood, P. C., Bayer, A. J., Yarnell, J. W. and Ben-Shlomo, Y. 2005. Glucoregulation has greater impact on cognitive performance than macro-vascular disease in men with type 2 diabetes: Data from the Caerphilly Study. European Journal of Epidemiology 20(9), pp. 761-768. (10.1007/s10654-005-2146-9)
2004
- Bayer, A. J., Pratt, R. D. and Kumar, D. 2004. A comparison of the cognitive benefits of donepezil in patients with cortical and subcortical vascular dementia [Abstract]. European Journal of Neurology 11(S2), pp. 36-37. (10.1111/j.1468-1331.2004.00919.x)
2003
- Bayer, A. J. and Fish, M. 2003. The doctor’s duty to the elderly patient in clinical trials. Drugs and Aging 20(15), pp. 1087-1097. (10.2165/00002512-200320150-00002)
- Tales, A., Muir, J. L., Jones, R., Bayer, A. J. and Snowden, R. J. 2003. The effects of saliency and task difficulty on visual search performance in ageing and Alzheimer's disease. Neuropsychologia 42(3), pp. 335-345. (10.1016/j.neuropsychologia.2003.08.002)
2002
- Tales, A., Muir, J. L., Bayer, A. J., Jones, R. and Snowden, R. J. 2002. Phasic visual alertness in Alzheimer's disease and ageing. NeuroReport 13(18), pp. 2557-2560.
- Baker, I., Pickering, J. E., Elwood, P. C., Bayer, A. J. and Ebrahim, S. 2002. Fibrinogen, viscosity and white blood cell count predict myocardial, but not cerebral infarction: evidence from the Caerphilly and Speedwell cohort. Thrombosis and Haemostasis 87(3), pp. 421-425.
- Tales, A., Muir, J. L., Bayer, A. J. and Snowden, R. J. 2002. Spatial shifts in visual attention in normal ageing and dementia of the Alzheimer type. Neuropsychologia 40(12), pp. 2000-2012. (10.1016/S0028-3932(02)00057-X)
- Elwood, P. C., Pickering, J. E., Bayer, A. J. and Gallacher, J. E. 2002. Vascular disease and cognitive function in older men in the Caerphilly cohort. Age and Ageing 31(1), pp. 43-48. (10.1093/ageing/31.1.43)
2001
- Sinclair, A. J., Gadsby, R., Penfold, S., Croxson, S. C. and Bayer, A. J. 2001. Prevalence of diabetes in care home residents. Diabetes Care 24(6), pp. 1066-1068. (10.2337/diacare.24.6.1066)
- Bandyopadhyay, S., Bayer, A. J. and O'Mahony, M. S. 2001. Age and gender bias in statin trials. QJM 94(3), pp. 127-132. (10.1093/qjmed/94.3.127)
- Greenwood, R. et al. 2001. The incidence and aetiology of stroke in the Caerphilly and Speedwell Collaborative Studies I: methods and incidence of events. Public Health 115(1), pp. 4-11. (10.1038/sj.ph.1900723)
- McCarron, P. et al. 2001. The incidence and aetiology of stroke in the Caerphilly and Speedwell Collaborative Studies II. Public Health 115(1), pp. 12-20. (10.1038/sj.ph.1900724)
2000
- Sinclair, A. J., Girling, A. J. and Bayer, A. J. 2000. Cognitive dysfunction in older subjects with diabetes mellitus: impact on diabetes self-management and use of care services. Diabetes Research and Clinical Practice 50(3), pp. 203-212. (10.1016/S0168-8227(00)00195-9)
- Bayer, A. J. and Tadd, W. 2000. Unjustified exclusion of elderly people from studies submitted to research ethics committee for approval: descriptive study. British Medical Journal (BMJ) 321(7267), pp. 992-993. (10.1136/bmj.321.7267.992)
- Sinclair, A. J., Bayer, A. J., Girling, A. J. and Woodhouse, K. W. 2000. Older adults, diabetes mellitus and visual acuity: a community-based case-control study. Age and Ageing 29(4), pp. 335-339. (10.1093/ageing/29.4.335)
1999
- Salek, S. S., Walker, M. D. and Bayer, A. J. 1999. A review of quality of life in Alzheimer's disease - Parts 1 and 2: Issues in assessing disease impact and drug effects - Reply [Letter]. PharmacoEconomics 16(4), pp. 417-419. (10.2165/00019053-199916040-00010)
- Salek, S. S., Walker, M. D. and Bayer, A. J. 1999. A review of quality of life in Alzheimer's disease: the authors reply [Letter]. PharmacoEconomics 15(6), pp. 641-644. (10.2165/00019053-199915060-00010)
- Bayer, A. J. 1999. Commentary: Another piece of the Alzheimer's jigsaw. British Medical Journal 318(7184), pp. 633. (10.1136/bmj.318.7184.633)
- Elwood, P. C. et al. 1999. Smoking, drinking, and other life style factors and cognitive function in men in the Caerphilly cohort. Journal of Epidemiology & Community Health 53(1), pp. 9-14. (10.1136/jech.53.1.9)
1998
- Sinclair, A. J., Bayer, A. J., Johnston, J., Warner, C. and Maxwell, S. R. J. 1998. Altered plasma antioxidant status in subjects with Alzheimer's disease and vascular dementia. International Journal of Geriatric Psychiatry 13(12), pp. 840-845. (10.1002/(SICI)1099-1166(1998120)13:12<840::AID-GPS877>3.0.CO;2-R)
- Salek, S. S., Walker, M. D. and Bayer, A. J. 1998. A review of quality of life in Alzheimer's disease. Part 2: Issues in assessing drug effects. PharmacoEconomics 14(6), pp. 613-627. (10.2165/00019053-199814060-00003)
- Walker, M. D., Salek, S. S. and Bayer, A. J. 1998. A review of quality of life in Alzheimer's disease. Part 1: Issues in assessing disease impact. PharmacoEconomics 14(5), pp. 499-530. (10.2165/00019053-199814050-00004)
1997
- Sinclair, A. J. and Bayer, A. J. 1997. British Geriatrics Society has produced document on diabetes care [Letter]. British Medical Journal (BMJ) 315(7121), pp. 1539. (10.1136/bmj.315.7121.1539a)
- Sinclair, A. J. and Bayer, A. J. 1997. Cognitive decline in elderly people [Commentary]. Journal of Human Hypertension 11(12), pp. 761-762.
- Sinclair, A. J., Allard, I. and Bayer, A. J. 1997. Observations of diabetes care in long-term institutional settings with measures of cognitive function and dependency. Diabetes Care 20(5), pp. 778-784. (10.2337/diacare.20.5.778)
- Rice, K., Warner, N., Tye, T. and Bayer, A. J. 1997. Telling the diagnosis to patients with Alzheimer's disease - geriatricians' and psychiatrists' practice differs [Letter]. British Medical Journal (BMJ) 314(7077), pp. 375. (10.1136/bmj.314.7077.375b)
1995
- Corr, S. and Bayer, A. J. 1995. Occupational therapy for stroke patients after hospital discharge- a randomized controlled trial. Clinical Rehabilitation 9(4), pp. 291-296. (10.1177/026921559500900403)
- Liddell, M. B., Bayer, A. J. and Owen, M. J. 1995. No evidence that common allelic variation in the Amyloid Precursor Protein (APP) gene confers susceptibility to Alzheimer's disease. Human Molecular Genetics 4(5), pp. 853-858. (10.1093/hmg/4.5.853)
- Powell, J., Hale, M. A. and Bayer, A. J. 1995. Symptoms of communication breakdown in dementia: carers' perceptions. International Journal of Language & Communication Disorders 30(1), pp. 67-75. (10.3109/13682829509031323)
1994
- Liddell, M. B., Williams, J., Bayer, A. J., Kaiser, F. and Owen, M. J. 1994. Confirmation of association between the e4 allele of apolipoprotein E and Alzheimer's disease. Journal of Medical Genetics 31(3), pp. 197-200. (10.1136/jmg.31.3.197)
1993
- Arino, S. and Bayer, A. J. 1993. Potential influence of previous medical pathology on use of thrombolysis in the elderly with suspected acute myocardial infarction. Gerontology 39(1), pp. 33-37. (10.1159/000213512)
1992
- Arino, S. and Bayer, A. J. 1992. Thrombolytic treatment for elderly patients [Letter]. British Medical Journal (BMJ) 305, pp. 1293-1294. (10.1136/bmj.305.6864.1293-b)
- Pathy, M. S. J., Bayer, A. J., Harding, K. and Dibble, A. 1992. Randomised trial of case finding and surveillance of elderly people at home. The Lancet 340(8824), pp. 890-893. (10.1016/0140-6736(92)93294-W)
1991
- Mulkerrin, E. C., Dewar, R., Condon, C., Curran, J., Bayer, A. J. and Laher, M. S. 1991. A retrospective study of myocardial infarction occurring in elderly patients in a coronary care unit. Irish Journal of Medical Science 160(8), pp. 257-258. (10.1007/BF02973401)
- Mulkerrin, E., Saran, R., Dewar, R., Harding, J. R., Bayer, A. J. and Finucane, P. 1991. The apex cardiac beat: not a reliable clinical sign in elderly patients. Age and Ageing 20(4), pp. 304-306. (10.1093/ageing/20.4.304)
- Long, C. A., Marin, P., Bayer, A. J., Shetty, H. G. M. and Pathy, M. S. J. 1991. Hypernatraemia in an adult in-patient population. Postgraduate Medical Journal -London- 67(789), pp. 643-645. (10.1136/pgmj.67.789.643)
1990
- Jones, M. J. et al. 1990. Cognitive and functional competence after anaesthesia in patients aged over 60: controlled trial of general and regional anaesthesia for elective hip or knee replacement. British Medical Journal (BMJ) 300(6741), pp. 1683-1687. (10.1136/bmj.300.6741.1683)
1989
- Marin, P. P., Bayer, A. J., Tomlinson, A. and Pathy, M. S. J. 1989. Attitudes of hospital doctors in Wales to use of intravenous fluids and antibiotics in the terminally ill. Postgraduate Medical Journal 65(767), pp. 650-652. (10.1136/pgmj.65.767.650)
- Watt, A. H., Bayer, A. J., Routledge, P. A. and Swift, C. G. 1989. Adenosine-induced respiratory and heart rate changes in young and elderly adults. British Journal of Clinical Pharmacology 27(2), pp. 265-267. (10.1111/j.1365-2125.1989.tb05360.x)
- Bayer, A. J., Pathy, M. S. J., Cameron, A., Venkateswalu, T., Ather, S. A., Mankikar, G. D. and Ghosh, A. K. 1989. A comparative study of conventional and controlled-release formulations of trazodone in elderly depressed patients. Clinical Neuropharmacology 12(Supp 1), pp. s50-s55.
- Bayer, A. J. et al. 1989. The pharmacokinetics of paroxetine in the elderly. Acta Psychiatrica Scandinavica Supplementum 80(S350), pp. 85-86. (10.1111/j.1600-0447.1989.tb07179.x)
1988
- Bayer, A. J. 1988. Presentation and management of myocardial infarction in the elderly. British Journal of Hospital Medicine 40(4), pp. 301-306.
- Joglekar, M., Mohanaruban, K., Bayer, A. J. and Pathy, M. S. 1988. Can old people on oral anticoagulants be safely managed as out-patients?. Postgraduate Medical Journal 64(756), pp. 775-777. (10.1136/pgmj.64.756.775)
- Day, J. J., Bayer, A. J., Chadha, J. S. and Pathy, M. S. J. 1988. Myocardial infarction in old people. The influence of diabetes mellitus. Journal of the American Geriatrics Society 36(9), pp. 791-794.
- Joglekar, M., Mohanaruban, K. and Bayer, A. J. 1988. Medication for the elderly: what do patients know?. British Journal of Clinical Practice 42(7), pp. 289-291.
- Bayer, A. J., Day, J. J., Finucane, P. and Pathy, M. S. J. 1988. Bioavailability and acceptability of a dispersible formulation of levodopa-benserazide in parkinsonian patients with and without dysphagia. Journal of Clinical Pharmacy and Therapeutics 13(3), pp. 191-194. (10.1111/j.1365-2710.1988.tb00179.x)
- Day, J. J., Bayer, A. J. and Pathy, M. S. 1988. A geriatric high dependency unit--an innovation in the care of the acutely ill elderly patient?. Comprehensive Gerontology Section A Clinical and Laboratory Sciences 2(2), pp. 67-70.
- Day, J. J., Bayer, A. J., McMahon, M., Pathy, M. S., Spragg, B. P. and Rowlands, D. C. 1988. Thiamine status, vitamin supplements and postoperative confusion. Age and Ageing 17(1), pp. 29-34. (10.1093/ageing/17.1.29)
- Busby, W., Bayer, A. J. and Pathy, J. 1988. Pulmonary embolism in the elderly. Age and Ageing 17(3), pp. 205-209. (10.1093/ageing/17.3.205)
1987
- Day, J. J., Bayer, A. J. and Pathy, M. S. 1987. Acute myocardial infarction: diagnostic difficulties and outcome in advanced old age. Age and Ageing 16(4), pp. 239-243. (10.1093/ageing/16.4.239)
- Bayer, A. J., Pathy, M. S. and Newcombe, R. G. 1987. Trials in acute stroke [Letter]. The Lancet 329(8548), pp. 1493. (10.1016/S0140-6736(87)92242-2)
- Chadha, J. S. and Bayer, A. J. 1987. Holt-Oram syndrome: delayed diagnosis. British Journal of Clinical Practice 41(5), pp. 754-755.
- Bayer, A. J., Pathy, M. and Newcombe, R. G. 1987. Double-blind randomised trial of intravenous glycerol in acute stroke. The Lancet 329(8530), pp. 405-408. (10.1016/S0140-6736(87)90117-6)
- Bayer, A. J., Gajewska, A., Stephens, M., Stark, J. M. and Pathy, J. 1987. Pharmacokinetics of ciprofloxacin in the elderly. Respiration 51(4), pp. 292-295.
- Bayer, A. J., Pathy, M. S. and Twining, C. 1987. The memory clinic. A new approach to the detection of early dementia. Drugs 33(Supp 2), pp. 84-89.
1986
- Day, J. J. and Bayer, A. J. 1986. A simple grading system to guide the prognosis after hip fracture in the elderly [Letter]. British Medical Journal (Clinical Research Edition) 293(6555), pp. 1173.
- Bayer, A. J., Bayer, E. M., Pathy, M. S. J. and Stoker, M. J. 1986. A double-blind controlled study of chlormethiazole and triazolam as hypnotics in the elderly. Acta Psychiatrica Scandinavica 73(s329), pp. 104-111. (10.1111/j.1600-0447.1986.tb10544.x)
- Pathy, M. S., Bayer, A. J. and Stoker, M. J. 1986. A double-blind comparison of chlormethiazole and temazepam in elderly patients with sleep disturbances. Acta Psychiatrica Scandinavica 73(s329), pp. 99-103. (10.1111/j.1600-0447.1986.tb10543.x)
- Bayer, A. J., Chadha, J. S., Farag, R. and Pathy, M. S. 1986. Changing presentation of myocardial infarction with increasing old age. Journal of the American Geriatrics Society 34(4), pp. 263-266.
- Pathy, J. and Bayer, A. J. 1986. Assessing exercise capacity in chronic heart failure [Letter]. British Medical Journal 292(6525), pp. 958-959.
- Bayer, A. J., Farag, R., Browne, S. and Pathy, M. S. 1986. Plasma electrolytes in elderly patients taking fixed combination diuretic. Postgraduate Medical Journal 62(725), pp. 159-162. (10.1136/pgmj.62.725.159)
- Bayer, A. J. and Pathy, M. S. 1986. Clinical and psychometric evaluation of two doses of loprazolam and placebo in geriatric patients. Current Medical Research and Opinion 10(1), pp. 17-24. (10.1185/03007998609111088)
1985
- Bayer, A. J., Ang, B. C. and Pathy, M. S. 1985. Cardiac arrests in a geriatric unit. Age and Ageing 14(5), pp. 271-276. (10.1093/ageing/14.5.271)
- Bayer, A. J. and Pathy, M. S. J. 1985. Requests for hypnotic drugs and placebo response in elderly hospital in-patients. Postgraduate Medical Journal 61(714), pp. 317-320. (10.1136/pgmj.61.714.317)
1983
- Bayer, A. J., Pathy, M. S. and Ankier, S. I. 1983. Pharmacokinetic and pharmacodynamic characteristics of trazodone in the elderly. British Journal of Clinical Pharmacology 16(4), pp. 371-376. (10.1111/j.1365-2125.1983.tb02180.x)
- Edwards, M., Owen, R. E. and Bayer, A. J. 1983. Hepatobiliary disease and chronic dental sepsis. The Practitioner 227(1378), pp. 665-668.
- Bayer, A. J., Pathy, M. S. and Ankier, S. I. 1983. An evaluation of the short-term hypnotic efficacy of loprazolam in comparison with nitrazepam in elderly patients. Pharmatherapeutica 3(7), pp. 468-474.