Professor James Lewis
Co-lead and Academic Director, Y Lab
- lewisj78@cardiff.ac.uk
- +44 (0)29 2087 9874
- 56 Park Place, Cathays, Cardiff, CF10 3AT
- Available for postgraduate supervision
Overview
@ylabwales we support and promote experimentation and innovation in public services in Wales.
I also conduct research in global health, focusing on conducting pragmatic evaluations of health system innovations across a range of disease areas and geographies.
Biography
Education
2001 –2005: PhD in Epidemiology at Imperial College London.
“Behavioural, demographic and social risk factors for HIV infection in rural Zimbabwe.” Received MRC funding.
1999 –2000: MSc in Applied Statistics at the University of Oxford.
Grade: Distinction. Gutierrez Toscano prize for joint top result. Received EPSRC funding.
1996 – 1999: BA (Hons) in Mathematics at the University of Cambridge.
Class: 2:1.
Professional memberships
Fellow of the Royal Geographical Society
Academic positions
2016 – 2018: Associate Professor, London School of Hygiene & Tropical Medicine. Based in London.
2013 – 2018: Deputy Director, Centre for Evaluation, London School of Hygiene & Tropical Medicine.
2013 – 2016: Senior Lecturer, London School of Hygiene & Tropical Medicine. Based in London.
2012 – 2013: Lecturer, London School of Hygiene & Tropical Medicine. Based in London.
2007 – 2012: Lecturer, London School of Hygiene & Tropical Medicine. Based at Aurum Institute, Johannesburg.
2005 – 2007: Research Fellow, London School of Hygiene & Tropical Medicine. Based at Aurum Institute, Johannesburg.
2001: Research assistant, National Centre for Epidemiology and Population Health, Australian National University, Canberra.
2000 – 2001: Research assistant, Centre for Socioeconomic Research, Welsh School of Pharmacy, University of Wales, Cardiff.
Committees and reviewing
Statistical reviewer, Lancet journals
Publications
2020
- Izzo, A. A.et al. 2020. An ecological study to evaluate the association of Bacillus Calmette-Guerin (BCG) vaccination on cases of SARS-CoV2 infection and mortality from COVID-19. PLoS ONE 15(12), article number: e0243707. (10.1371/journal.pone.0243707)
- Stagg, H. R.et al. 2020. Temporal factors and missed doses of tuberculosis treatment: a causal associations approach to analyses of digital adherence data. Annals of the American Thoracic Society 17(4), pp. 438-449. (10.1513/AnnalsATS.201905-394OC)
2019
- Hargreaves, J. R.et al. 2019. Five challenges in the design and conduct of IS trials for HIV prevention and treatment. Journal of Acquired Immune Deficiency Syndromes 82, pp. S261-S270. (10.1097/QAI.0000000000002192)
- Hensen, B.et al. 2019. Application of an HIV prevention cascade to identify gaps in increasing coverage of voluntary medical male circumcision services in 42 rural Zambian communities. AIDS and Behavior 23(5), pp. 1095-1103. (10.1007/s10461-019-02407-w)
2018
- Lewis, J. J.et al. 2018. Evaluation of a medication monitor-based treatment strategy for drug-sensitive tuberculosis patients in China: study protocol for a cluster randomised controlled trial. Trials 19, pp. -., article number: 398. (10.1186/s13063-018-2650-3)
- Page-Shipp, L.et al. 2018. Household point of care CD4 testing and isoniazid preventive therapy initiation in a household TB contact tracing programme in two districts of South Africa. PLoS ONE 13(3), article number: e0192089. (10.1371/journal.pone.0192089)
2017
- Mastropasqua, R.et al. 2017. Black patients sustain vision loss while White and South Asian patients gain vision following delamination or segmentation surgery for tractional complications associated with proliferative diabetic retinopathy. Eye 31(10), pp. 1468-1474. (10.1038/eye.2017.95)
- Wingfield, T.et al. 2017. Socioeconomic support to improve initiation of tuberculosis preventive therapy and increase tuberculosis treatment success in Peru: a household-randomised, controlled evaluation. Lancet 389, pp. 16-16.
- Wingfield, T.et al. 2017. A randomized controlled study of socioeconomic support to enhance tuberculosis prevention and treatment, Peru. Bulletin of the World Health Organization 95, pp. 270-280. (10.2471/BLT.16.170167)
2016
- Greenland, K.et al. 2016. Multiple behaviour change intervention for diarrhoea control in Lusaka, Zambia: a cluster randomised trial. Lancet Global Health 4(12), pp. e966-e977. (10.1016/S2214-109X(16)30262-5)
- Kliemann, B. S.et al. 2016. Socioeconomic determinants of antibiotic consumption in the state of Sao Paulo, Brazil: The effect of restricting over-the-counter sales. PLoS ONE 11(12), pp. -., article number: e0167885. (10.1371/journal.pone.0167885)
- Wingfield, T.et al. 2016. The economic effects of supporting tuberculosis-affected households in Peru. European Respiratory Journal 48(5), pp. 1396-1410. (10.1183/13993003.00066-2016)
- Blanchet, K.et al. 2016. A mixed methods protocol to evaluate the effect and cost-effectiveness of an Integrated electronic Diagnosis Approach (IeDA) for the management of childhood illnesses at primary health facilities in Burkina Faso. Implementation Science 11, pp. -., article number: 111. (10.1186/s13012-016-0476-5)
- Jha, S.et al. 2016. Cost-effectiveness of automated digital microscopy for diagnosis of active tuberculosis. PLoS ONE 11(6), pp. -., article number: e0157554. (10.1371/journal.pone.0157554)
- Velen, K.et al. 2016. Household HIV testing uptake among contacts of TB patients in South Africa. PLoS ONE 11(5), pp. -., article number: e0155688. (10.1371/journal.pone.0155688)
- Hermans, S. M.et al. 2016. The timing of tuberculosis after isoniazid preventive therapy among gold miners in South Africa: a prospective cohort study. BMC Medicine 14, pp. -., article number: 45. (10.1186/s12916-016-0589-3)
2015
- Ononge, S.et al. 2015. Effectiveness and safety of misoprostol distributed to antenatal women to prevent postpartum haemorrhage after child-births: a stepped-wedge cluster-randomized trial. BMC Pregnancy and Childbirth 15, pp. -., article number: 315. (10.1186/s12884-015-0750-6)
- Hensen, B.et al. 2015. Frequency of HIV-testing and factors associated with multiple lifetime HIV-testing among a rural population of Zambian men. BMC Public Health 15, article number: 960. (10.1186/s12889-015-2259-3)
- Liu, X.et al. 2015. Effectiveness of electronic reminders to improve medication adherence in tuberculosis patients: a cluster-randomised trial. PLoS Medicine 12(9), article number: e1001876. (10.1371/journal.pmed.1001876)
- van Halsema, C. L.et al. 2015. The effect of antiretroviral therapy and CD4 count on markers of infectiousness in HIV-associated tuberculosis. Journal of Acquired Immune Deficiency Syndromes 70(1), pp. 104-108. (10.1097/QAI.0000000000000684)
- Wingfield, T.et al. 2015. Designing and implementing a socioeconomic intervention to enhance TB control: operational evidence from the CRESIPT project in Peru. BMC Public Health 15, pp. -., article number: 810. (10.1186/s12889-015-2128-0)
- Hargreaves, J. R.et al. 2015. Five questions to consider before conducting a stepped wedge trial. Trials 16, article number: 350. (10.1186/s13063-015-0841-8)
- Copas, A. J.et al. 2015. Designing a stepped wedge trial: three main designs, carry-over effects and randomisation approaches. Trials 16, article number: 352. (10.1186/s13063-015-0842-7)
- Beard, E.et al. 2015. Stepped wedge randomised controlled trials: systematic review of studies published between 2010 and 2014. Trials 16, pp. -., article number: 353. (10.1186/s13063-015-0839-2)
- Prost, A.et al. 2015. Logistic, ethical, and political dimensions of stepped wedge trials: critical review and case studies. Trials 16, pp. -., article number: 351. (10.1186/s13063-015-0837-4)
- Davey, C.et al. 2015. Analysis and reporting of stepped wedge randomised controlled trials: synthesis and critical appraisal of published studies, 2010 to 2014. Trials 16, pp. -., article number: 358. (10.1186/s13063-015-0838-3)
- Ismail, N. A.et al. 2015. Performance of a novel algorithm using automated digital microscopy for diagnosing tuberculosis. American Journal of Respiratory and Critical Care Medicine 191(12), pp. 1443-1449. (10.1164/rccm.201502-0390OC)
- Vynnycky, E.et al. 2015. Tuberculosis control in South African gold mines: Mathematical modeling of a trial of community-wide isoniazid preventive therapy. American Journal of Epidemiology 181(8), pp. 619-632. (10.1093/aje/kwu320)
- Hensen, B.et al. 2015. Factors associated with HIV-testing and acceptance of an offer of home-based testing by men in rural Zambia. AIDS and Behavior 19(3), pp. 492-504. (10.1007/s10461-014-0866-0)
- Mathema, B.et al. 2015. Molecular epidemiology of Mycobacterium tuberculosis among South African gold miners. Annals of the American Thoracic Society 12(1), pp. 12-20. (10.1513/AnnalsATS.201404-150OC)
- van Halsema, C. L.et al. 2015. Clinical relevance of nontuberculous mycobacteria isolated from sputum in a gold mining workforce in South Africa: an observational, clinical study. BioMed Research International 2015, article number: 959107. (10.1155/2015/959107)
2014
- Churchyard, G. J.et al. 2014. A trial of mass isoniazid preventive therapy for tuberculosis control. New England Journal of Medicine 370(4), pp. 301-310. (10.1056/NEJMoa1214289)
2004
- Salek, M.et al. 2004. Quality of life improvement in treatment of psoriasis with intermittent short course Cyclosporin (Neoral®). Quality of Life Research 13(1), pp. 91-95. (10.1023/B:QURE.0000015293.69661.ff)
- Grassly, N.et al. 2004. Comparison of household-survey estimates with projections of mortality and orphan numbers in sub-Saharan Africa in the era of HIV/AIDS. Population Studies 58(2), pp. 207-217. (10.1080/0032472042000224431)
2003
- Becker, N. G.et al. 2003. Age-specific back-projection of HIV diagnosis data. Statistics in Medicine 22(13), pp. 2177-2190. (10.1002/sim.1406)
@ylabwales we are conducting research on public service innovation, including working with projects on our Innovate to Save programme https://www.nesta.org.uk/project/innovate-save/
The primary evaluation methodologies I have applied in global health have been cluster randomised trials and stepped wedge trials, always in interdisciplinary teams. I currently work on projects in Wales, Peru, Burkina Faso and India. I lived in Johannesburg for seven years and I have also worked on projects in China, Zimbabwe and Zambia.
Supervision
I am interested in supervising PhD and Professional Doctorate students in the areas of:
- public services innovation
- social innovation
- smart cities
- global health
