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Jake Brynley Bowd

Research student, School of Engineering


Jake is a Medical Engineering PhD candidate under the supervision of Professor Cathy Holt and Dr Gemma Whatling.

Jake’s PhD is titled ‘Does gait retraining have the potential to slow OA development and prolong the benefits of knee realignment surgery (High Tibial Osteotomy (HTO))?’.

Jake actively contributes to the School of Engineering in Open Days, school visits and teaching. Additionally, Jake actively seeks funding to support undergraduate summer placement projects for which he has already been involved in 3 summer placements which has allowed Medical Engineering students to explore the research in the Musculoskeletal Biomechanics Research Facility.

Jake is an active member of the Cardiff Institute of Tissue Engineering and Repair (CITER) where he spent two years on the Society Committee.

Jake is scheduled to defend his PhD thesis in the Autumn of 2021. He wishes to remain in academia and to work in a multidisciplinary team researching in the field of orthopaedic biomechanics. Ultimately, Jake wishes to pursue a career in the above research field which has a direct influence on clinical decision making, as well as collaborating and influencing industry.


Research interests

To-date, Jake’s PhD has led to numerous National and International conference talks and a publication in a peer-reviewed Journal. Jake has secured funding opportunities from OATech+ Network for which Jake spent 6 weeks at the Human Movement Biomechanics Research Group at KU Leuven to gain an appreciation and understanding for musculoskeletal modelling and its applicability to clinical translation.

Additionally, Jake has been awarded the CITER Young Investigators Bursary to present work at the 2019 International Combined Orthopaedic Research Societies Meeting.


Does gait retraining have the potential to slow OA development and prolong the benefits of knee realignment surgery (High Tibial Osteotomy (HTO))?

The PhD aims to quantify external knee adduction moments as well as using musculoskeletal models to determine load distribution in the tibia subchondral bone pre-to-post-HTO. Gait and full body joint biomechanics are being quantified for healthy volunteers, patients with early-OA, and patients pre-and post-HTO, to reveal biomechanical differences. Gait retraining is being quantified biomechanically, using patient reported outcome measures and via the Cardiff Classifier. This will generate recommendations for gait modifications that are beneficial to patients with knee OA, report whether gait retraining restores similar biomechanics to the offloading knee brace and contribute to rehabilitation protocols leading to clinical trials.

Funding source

Biomechanics and Bioengineering Research Centre Versus Arthritis





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