Dr Anzelika Trinca
(she/her)
Postdoctoral Research Associate
- RubinaA@cardiff.ac.uk
- +44 29206 87022
- Henry Wellcome Building for Biomedical Research, Room UG10, University Hospital of Wales, Heath Park, Cardiff, CF14 4XN
Overview
I'm a Post-Doc in Prof. Eddie Wang's lab, as part of the 'Cytomegalovirus and Adenovirus' group, within the Divison of Infection and Immunity. I'm interested in understanding the viral immune evasion strategies employed by human Cytomegalovirus (HCMV) to evade its host. Specifically, how the virus manipulates NK- and T-cell function to dampen immune activation. My publications are available under my maiden name 'Rubina' at Google Scholar.
Publication
2023
- Rubina, A. et al. 2023. ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways. Proceedings of the National Academy of Sciences 120(33), article number: e2303155120. (10.1073/pnas.2303155120)
- Trinca, A. 2023. Investigating the role of ADAM17 in human cytomegalovirus infection. PhD Thesis, Cardiff University.
2022
- Saud, Z. et al. 2022. The SARS-CoV2 envelope differs from host cells, exposes pro-coagulant lipids, and is disrupted in vivo by oral rinses. Journal of Lipid Research 63(6), article number: 100208. (10.1016/j.jlr.2022.100208)
- Tizaoui, C. et al. 2022. Ozone for SARS-CoV-2 inactivation on surfaces and in liquid cell culture media. Journal of Hazardous Materials 428, article number: 128251. (10.1016/j.jhazmat.2022.128251)
2021
- Clement, M. et al. 2021. CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor. Proceedings of the National Academy of Sciences 118(29), article number: e2019639118. (10.1073/pnas.2019639118)
2019
- McLaren, J. et al. 2019. IL-33 augments virus-specific memory T Cell inflation and potentiates the efficacy of an attenuated cytomegalovirus-based vaccinea. Journal of Immunology 202(3), pp. 943-955. (10.4049/jimmunol.1701757)
Articles
- Rubina, A. et al. 2023. ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways. Proceedings of the National Academy of Sciences 120(33), article number: e2303155120. (10.1073/pnas.2303155120)
- Saud, Z. et al. 2022. The SARS-CoV2 envelope differs from host cells, exposes pro-coagulant lipids, and is disrupted in vivo by oral rinses. Journal of Lipid Research 63(6), article number: 100208. (10.1016/j.jlr.2022.100208)
- Tizaoui, C. et al. 2022. Ozone for SARS-CoV-2 inactivation on surfaces and in liquid cell culture media. Journal of Hazardous Materials 428, article number: 128251. (10.1016/j.jhazmat.2022.128251)
- Clement, M. et al. 2021. CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor. Proceedings of the National Academy of Sciences 118(29), article number: e2019639118. (10.1073/pnas.2019639118)
- McLaren, J. et al. 2019. IL-33 augments virus-specific memory T Cell inflation and potentiates the efficacy of an attenuated cytomegalovirus-based vaccinea. Journal of Immunology 202(3), pp. 943-955. (10.4049/jimmunol.1701757)
Thesis
- Trinca, A. 2023. Investigating the role of ADAM17 in human cytomegalovirus infection. PhD Thesis, Cardiff University.
Biography
Education
2018 - 2022 - PhD in Viral Immunology, Cardiff University
2016 - 2017 - MRes in Biosciences, Swansea University
2013 - 2016 - BSc in Molecular Biology, University of Hertfordshire
Academic positions
2022 - Present - Research Associate, Division of Infection & Immunity, Cardiff University
2018 - Research Technician, Division of Infection & Immunity, Cardiff University
Honours and awards
2023 - Cardiff University Infection & Immunity Annual Meeting Postdoc Poster Presentation Award
2023 - 20th Annual Meeting of the Society for Natural Immunity (NK2023) Travel Award
2022 - Microbiology Society Annual Conference 2022 Travel Award
2021 - Cardiff University Infection & Immunity Annual Meeting PhD Poster Presentation Award
2021 - Microbiology Society Annual Conference Online 2021 Most Promising Science Poster Prize
Professional memberships
- Microbiology Society
- Society for Natural Immunity
Specialisms
- Virology
- Immunology