Thomas Freeman

Thomas Freeman

Research student, School of Psychology

Email:
freemant5@cardiff.ac.uk
Telephone:
+44 (0)29 208 70141
Location:
Tower Building, 70 Park Place, Cardiff, CF10 3AT

Research summary

Alzheimer's Disease is the leading cause of dementia and is charaterised by chronic neurodegeneration as well as the accumulations of β-amyloid "plaques" and tau "tangles". The aggregation of β-amyloid peptides was first proposed as the cause of the disease in 1991. However, we still have no disease modifying therapies.

My research aims to uncover a physiological role for the β-amyloid in normal cognition. We will use an antibody to inhibit its production, before analysing any effect on learning and memory. We will also utilise a novel murine model of the disease which more accurately represents the human condition.

Research interests

Funding

Wellcome Trust

Research group

Behavioural Neuroscience

Research collaborators

Professor Mark Good

Dr Emma Kidd (Pharmacy)

Dr Rhian Thomas (Pharmacy)

Areas of expertise