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Meddygaeth

The School of Medicine offers research degrees in the medical disciplines such as cancer, immunology, infection, immunity, neurosciences, mental health and population medicine.

PhD, MPhil, MD Amser llawn, rhan-amser Rhaglen

Mathemateg Bur

Mae ymchwil yn y maes yn cynnwys: Hafaliadau differol rhif a chyffredin; Dadansoddiad swyddogaethol; Theori sbectrol cyfrifiadurol a dadansoddol; Mecaneg cwantwm; Theori rhif a’i ddefnydd; Ffiseg mathemategol; Algebras gweithredydd; Geometreg algebraidd.

PhD, MPhil Amser llawn, rhan-amser Maes

Mathemateg Gymhwysol

Mae ymchwil yn y maes hwn yn cwmpasu: Lluosogi ton mewn cyfryngau anhomogenaidd; Homogeneiddiad; Mecaneg hylif; Mecaneg strwythurol a solet; Dadansoddiad rhifiadol a chyfrifiadureg gwyddonol; Modelu mathemategol cymhwysol; Effeithiau cof; Problemau gwrthdro; Trawsnewid hanfodol.

PhD, MPhil Amser llawn, rhan-amser Maes

Peirianneg: Ynni a'r Amgylchedd

Un o dri thema ymchwil yr Ysgol yw Ynni a’r Amgylchedd, sy’n ceisio datblygu technoleg ynni a chwarae rôl allweddol wrth fynd i’r afael â’r galw cynyddol ar gyfer technolegau carbon isel a chynaliadwy, tra’n lleihau’r effaith amgylcheddol a sicrhau amgylchedd cynaliadwy.

PhD, MPhil, EngD Amser llawn, rhan-amser Maes

Peirianneg: Mecaneg, Deunyddiau ac Uwch-Weithgynhyrchu

Mae thema ymchwil eang Mecaneg, Deunyddiau ac Uwch-Weithgynhyrchu yn ymgorffori ymchwil arloesol sy’n meithrin arloesedd a chynaliadwyedd, yn cefnogi datblygiad economaidd a chymdeithasol, ac yn cyfrannu at welliannau mewn iechyd ac ansawdd bywyd drwy sicrhau diogelwch a pherfformiad gorau deunyddiau a strwythurau.

PhD, MPhil, EngD Amser llawn, rhan-amser Maes

Peirianneg: Iechyd, Technoleg a'r Byd Digidol

Mae’r thema ymchwil Iechyd, Technoleg, a’r Byd Digidol yn darparu fframwaith ar gyfer yr ymchwil a gyflawnir ym meysydd Peirianneg Cyfathrebu Amledd Uchel a Pheirianneg Feddygol, Ffiseg Feddygol, ac Electroneg Feddygol. Mae’r cyfuniad o’r disgyblaethau hyn yn galluogi dull gwirioneddol arloesol ac yn galluogi datrysiadau newydd cyffrous ar gyfer diogelwch, gofal iechyd a gofynion meddygol cymdeithas fodern.

PhD, MPhil, EngD Amser llawn, rhan-amser Maes

Astudio clefyd niwroseiciatrig dynol mewn niwronau dynol diffygiol DLG2

Mae'r prosiect PhD hwn mewn Meddygaeth yn ceisio deall rôl y DLG2 yn ystod datblygiad niwral a niwronau aeddfed gan ddefnyddio amrywiaeth o dechnegau.

Prosiect

Integration of genetic and functional data to identify drug targets and enhance risk prediction

Integrating brain expression and protein-protein interaction data with genomic data identified a network of immune-related genes implicated in Alzheimer’s disease (AD) susceptibility.

Prosiect

Characterising DNA damage repair in Huntington’s disease

Parkinson’s disease (PD) is the second most common neurodegenerative disorder and results from the selective loss of dopaminergic neurons within the Substantia nigra pars compacta.

Prosiect

Detecting dysfunction in the single-cell gene networks underlying Parkinson’s disease

Parkinson’s disease (PD) is the second most common neurodegenerative disorder and results from the selective loss of dopaminergic neurons within the Substantia nigra pars compacta.

Prosiect

Microglial NFAT signalling and Alzheimer’s disease genetic risk networks

In this project, you will develop skills in molecular biological, cell culture, genome biology and bioinformatics.

Prosiect

The molecular basis of cognitive flexibility

This project examines transcriptomes in key brain regions at critical periods to determine the molecular bases of flexible behaviour.

Prosiect

Investigating peroxisome dysregulation in Alzheimer’s disease

In this project you will first determine how peroxisomes respond to the specific pathogenic proteins associated with AD in vivo.

Prosiect

Machine Learning for Prediction in Alzheimer's Disease: Identifying Novel Biologically Valid Diagnostic Categories to Inform Precision Medicine

The project will involve investigating the ability of machine learning.

Prosiect

Targeting LAG3+ T cells for Cancer Immunotherapy

This study will look at the control of adaptive immunity in health and inflammation by human blood and mucosal gamma/delta T cells.

Prosiect

Alzheimer’s disease: Understanding the interaction of microglia risk genes

The aim of this project is to understand the interdependence of specific risk alleles and highlight the possibility of adjunctive therapies targeting different ‘arms’ of the immune cells to treat the disease.

Prosiect

Investigating the childhood neurodevelopmental origins of adult mental illness

This PhD utilises new data generated by a Wellcome Trust Collaborative Award between Cardiff and Bristol Universities to test hypotheses on why child NDDs show links with later adult mental illness.

Prosiect

Flexible vectors for immunotherapy against cancer and pathogens

This project aims to determine pathways that can drive the growth of particular types of NK and T cells that are optimised to provide better protection from disease. We will use cytomegalovirus and leukaemic cells as systems of analysis.

Prosiect

Role of a mouse ortholog of CR1 (crry) in the 3xTG model of Alzheimer’s Disease (AD)

In order to explore further roles of Crry, we have generated and established a 3xTG/Crry-/- colony, but have not yet had resources to explore further the impact of Crry deficiency in this model.

Prosiect

Enhancing immune stimulation for novel anti-cancer viral vaccine vectors

We will combine cutting-edge proteomics with molecular virology and immunology to determine how HCMV induces such strong responses, enabling us to generate optimised vaccine vectors.

Prosiect

Optimizing adult mental health outcomes in children with neurodevelopmental problems: interplay of social and genetic factors

This PhD project provides a unique opportunity to develop advanced methodological and analytic skills in the field of developmental psychopathology.

Prosiect

School experiences in children at high genetic risk of mental health problems

This project will provide important insights into why children with a genomic disorder struggle in school.

Prosiect

Molecular mechanisms of CRISPR Cas9 nickase-induced CAG/CTG repeat contraction: Implications for gene editing in expanded repeat disorders

The aim of this project is to understand how contractions occur at the molecular level such that we can make a potential gene editing-based treatment safer and more efficient.

Prosiect