Ewch i’r prif gynnwys

Design of experiments in regression models with correlated observations

Please note that this project is self-funded.

The main aim of the project is to develop the theoretical and methodological principles for the problem of optimal experimental design in the case of correlated observations.

Background

The design of experiments is an area of mathematical sciences which has direct economic impact. Optimal designs allow saving time, materials and other resources. New design methodologies are required due to growing complexity of real world problems, for example, technological changes in quality and quantity of measured data. The theory of the design of experiments involves statistical, optimization and simulation principles, various mathematical techniques and extensive computing.

The theory of statistical experimental design is an important link between the experimental and the modelling worlds. Designing experiments aims at extracting the maximal information from an experiment. Up to now the theory of experimental design mostly deals with uncorrelated observations. In most modern applications, however, the experimental observations are correlated. The whole philosophy of experimental design in this case becomes more complicated.

Project aims and methods

The project is interdisciplinary in nature and will include elements of theoretical probability and applied statistics. The main objective of the project is to develop the theoretical and methodological principles for the problem of optimal experimental design in the case of correlated observations.

Specifically, statistical procedures and computer software will be developed for solving specific classes of applied problems including optimal designs for spatial models, sequential designs for computer experiments, efficient designs for the evaluation of the pharmacokinetics and the pharmacodynamics of drugs.

Goruchwylwyr

Prof Anatoly Zhigljavsky photograpgh

Yr Athro Anatoly Zhigljavsky

Chair in Statistics

Email:
zhigljavskyaa@caerdydd.ac.uk
Telephone:
+44 (0)29 2087 5076
Photograph of Dr Andre Pepelyshev

Dr Andrey Pepelyshev

Lecturer

Email:
pepelyshevan@caerdydd.ac.uk
Telephone:
+44 (0)29 2087 5530

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