Dr Charles Heard

2021

• Alrashidi, A. et al. 2021. A time-kill assay study on the synergistic bactericidal activity of pomegranate rind extract and Zn (II) against Methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis, Escherichia coli, and Pseudomonas aeruginosa. Biomolecules 11(12), article number: 1889. (10.3390/biom11121889)
• Yonbawi, A. R., Abdallah, H. M., Alkhilaiwi, F. A., Koshak, A. E. and Heard, C. M. 2021. Anti-Proliferative, Cytotoxic and Antioxidant Properties of the Methanolic Extracts of Five Saudi Arabian Flora with Folkloric Medicinal Use: Aizoon canariense, Citrullus colocynthis, Maerua crassifolia, Rhazya stricta and Tribulus macropterus. Plants 10(10), article number: 2073. (10.3390/plants10102073)
• Celiksoy, V., Moses, R. L., Sloan, A. J., Moseley, R. and Heard, C. M. 2021. Synergistic in vitro antimicrobial activity of pomegranate rind extract and zinc (II) against Micrococcus luteus under planktonic and biofilm conditions. Pharmaceutics 13(6), article number: 851. (10.3390/pharmaceutics13060851)

2020

• Varricchio, C., Beirne, K., Aeschlimann, P., Heard, C., Rozanowska, M., Votruba, M. and Brancale, A. 2020. Discovery of Novel 2-Aniline-1,4-naphthoquinones as potential new drug treatment for Leber’s hereditary optic neuropathy (LHON). Journal of Medicinal Chemistry 63(22), pp. 13638 -13655. (10.1021/acs.jmedchem.0c00942)
• Heard, C. M. 2020. An ex vivo skin model to probe modulation of local cutaneous arachidonic acid inflammation pathway. Journal of Biological Methods 7(4), article number: e138. (10.14440/jbm.2020.319)
• Celiksoy, V., Moses, R. L., Sloan, A. J., Moseley, R. and Heard, C. M. 2020. Evaluation of the in vitro oral wound healing effects of pomegranate (Punica granatum) rind extract and punicalagin, in combination with Zn (II). Biomolecules 10(9), article number: 1234. (10.3390/biom10091234)
• Varricchio, C., Beirne, K., Heard, C., Newland, B., Rozanowska, M., Brancale, A. and Votruba, M. 2020. The ying and yang of idebenone: Not too little, not too much - cell death in NQO1 deficient cells and the mouse retina. Free Radical Biology and Medicine 152, pp. 551-560. (10.1016/j.freeradbiomed.2019.11.030)
• Bender, L. et al. 2020. A novel dual action monolithic thermosetting hydrogel loaded with lidocaine and metronidazole as a potential treatment for alveolar osteitis. European Journal of Pharmaceutics and Biopharmaceutics 149, pp. 85-94. (10.1016/j.ejpb.2020.01.007)
• Morgan, S. R. et al. 2020. Controlled in vitro delivery of voriconazole and diclofenac to the cornea using contact lenses for the treatment of Acanthamoeba keratitis. International Journal of Pharmaceutics 579, article number: 119102. (10.1016/j.ijpharm.2020.119102)
• Hewitt, M. G. et al. 2020. In Vitro Topical Delivery of Chlorhexidine to the Cornea: Enhancement Using Drug-Loaded Contact Lenses and β-Cyclodextrin Complexation, and the Importance of Simulating Tear Irrigation. Molecular Pharmaceutics 17(4), pp. 1428-1441. (10.1021/acs.molpharmaceut.0c00140)
• Yee Lim, S. et al. 2020. Mucoadhesive thin films for the simultaneous delivery of microbicide and anti-inflammatory drugs in the treatment of periodontal diseases. International Journal of Pharmaceutics 573, article number: 118860. (10.1016/j.ijpharm.2019.118860)

2019

• Barbieri, M. and Heard, C. M. 2019. Isolation of punicalagin from Punica granatum rind extract using mass-directed semi-preparative ESI-AP single quadrupole LC-MS. Journal of Pharmaceutical and Biomedical Analysis 166, pp. 90-94. (10.1016/j.jpba.2018.12.033)

2018

• Yurdasiper, A., Ertan, G. and Heard, C. M. 2018. Enhanced delivery of naproxen to the viable epidermis from an activated poly N-isopropylacrylamide (PNIPAM) Nanogel: Skin penetration, modulation of COX-2 expression and rat paw Oedema. Nanomedicine: Nanotechnology, Biology and Medicine 14(7), pp. 2051-2059. (10.1016/j.nano.2018.05.017)
• Davison, Z., Nicholson, R. I., Hiscox, S. and Heard, C. M. 2018. Co-administration of fish oil with signal transduction inhibitors has anti-migration effects in breast cancer cell lines, in vitro. The Open Biochemistry Journal 12(1), pp. 130-148. (10.2174/1874091X01812010130)
• Zulfakar, M. H., Chan, L. M., Rehman, K., Wai, L. K. and Heard, C. 2018. Coenzyme Q10-loaded fish oil-based Bigel System: probing the delivery across porcine skin and possible interaction with fish oil fatty acids. AAPS PharmSciTech 19(3), pp. 1116-1123. (10.1208/s12249-017-0923-x)

2017

• Houston, D. M. J., Bugert, J. J., Denyer, S. P. and Heard, C. M. 2017. Potentiated virucidal activity of pomegranate rind extract (PRE) and punicalagin against Herpes simplex virus (HSV) when co-administered with zinc (II) ions, and antiviral activity of PRE against HSV and aciclovir-resistant HSV. PLoS ONE 12(6), article number: e0179291. (10.1371/journal.pone.0179291)
• Houston, D., Bugert, J., Denyer, S. P. and Heard, C. M. 2017. Anti-inflammatory activity of Punica granatum L. (Pomegranate) rind extracts applied topically to ex vivo skin. European Journal of Pharmaceutics and Biopharmaceutics 112, pp. 30-37. (10.1016/j.ejpb.2016.11.014)
• Houston, D. M. J., Robins, B., Bugert, J. J., Denyer, S. P. and Heard, C. M. 2017. In vitro permeation and biological activity of punicalagin and zinc (II) across skin and mucous membranes prone to Herpes simplex virus infection. European Journal of Pharmaceutical Sciences 96, pp. 99-106. (10.1016/j.ejps.2016.08.013)

2016

• Chan, W., Akhbanbetova, A., Quantock, A. J. and Heard, C. M. 2016. Topical delivery of a Rho-kinase inhibitor to the cornea via mucoadhesive film. European Journal of Pharmaceutical Sciences 91, pp. 256-264. (10.1016/j.ejps.2016.05.016)
• Zulfakar, M. H., Porter, R. and Heard, C. 2016. In vivoresponse of GsdmA3Dfl/+ mice to topically applied fish oil - effects on cellular markers and macrophages. FEBS Open Bio 6(8), pp. 827-834. (10.1002/2211-5463.12095)

2015

• Heard, C. M. 2015. Ethanol and other alcohols: old enhancers, alternative perspectives. In: Dragicevic, N. and Maibach, H. I. eds. Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement: Modification of the Stratum Corneum. Springer, pp. 151-172., (10.1007/978-3-662-47039-8_10)

2014

• Abu Samah, N. H. and Heard, C. M. 2014. The effects of topically applied polyNIPAM-based nanogels and their monomers on skin cyclooxygenase expression,ex vivo. Nanotoxicology 8(1), pp. 100-106. (10.3109/17435390.2012.754511)
• Heard, C. M. and Brain, K. R. 2014. Chiral separations. In: Street, G. ed. Highly selective separations in biotechnology. London: Blackie Academic and Professional, pp. 179-206.

2013

• Lau, W. M., Heard, C. M. and White, A. W. 2013. Design, synthesis and in vitro degradation of a novel co-drug for the treatment of psoriasis. Pharmaceutics 5(2), pp. 232-245. (10.3390/pharmaceutics5020232)
• Abu Samah, N. H. and Heard, C. M. 2013. Enhanced in vitro transdermal delivery of caffeine using a temperature- and pH-sensitive nanogel, poly(NIPAM-co-AAc). International Journal of Pharmaceutics 453(2), pp. 630-640. (10.1016/j.ijpharm.2013.05.042)

2012

• Wallace, E., Ong, C. M. Y. and Heard, C. M. 2012. Delivery of atovaquone and proguanil across sublingual membranes, in vitro. Pharmaceutical Development and Technology 17(6), pp. 770-776. (10.3109/10837450.2011.580760)
• Lau, W. M., Ng, K. W., Sakenyte, K. and Heard, C. M. 2012. Distribution of esterase activity in porcine ear skin, and the effects of freezing and heat separation. International Journal of Pharmaceutics 433(1-2), pp. 10-15. (10.1016/j.ijpharm.2012.04.079)
• Zulfakar, M. H., Ong, C. M. and Heard, C. M. 2012. The effects of betamethasone dipropionate and fish oil on HaCaT proliferation and apoptosis. International Journal of Pharmaceutics 434(1-2), pp. 399-405. (10.1016/j.ijpharm.2012.06.008)

2011

• Abu Samah, N. H. and Heard, C. M. 2011. Topically applied KTTKS: a review. International Journal of Cosmetic Science 33(6), pp. 483-490. (10.1111/j.1468-2494.2011.00657.x)
• Zulfakar, M. H., Alex, A., Povazay, B., Drexler, W., Thomas, C. P., Porter, R. M. and Heard, C. M. 2011. In vivo response of GsdmA3Dfl/+ mice to topically applied anti-psoriatic agents: effects on epidermal thickness, as determined by optical coherence tomography and H&E staining. Experimental Dermatology 20(3), pp. 269-272. (10.1111/j.1600-0625.2010.01233.x)
• Lau, W. M., Ng, K. W., White, A. W. and Heard, C. M. 2011. Therapeutic and cytotoxic effects of the novel antipsoriasis codrug, naproxyl-dithranol, on HaCaT cells. Molecular Pharmaceutics 8(6), pp. 2398-2407. (10.1021/mp200327k)

2010

• Singka, G. S. L., Abu Samah, N. H., Zulfakar, M., Yurdasiper, A. and Heard, C. M. 2010. Enhanced topical delivery and anti-inflammatory activity of methotrexate from an activated nanogel. European Journal of Pharmaceutics and Biopharmaceutics 76(2), pp. 275-281. (10.1016/j.ejpb.2010.06.014)
• Davison, Z., Nicholson, R. I., Denyer, S. P. and Heard, C. M. 2010. A novel diffusion cell model for the in vitro assessment of transcutaneous breast cancer therapeutics: effect of permeants on MCF-7 cells cultured within the receptor compartment. European Journal Of Pharmaceutics and Biopharmaceutics 75(3), pp. 411-417. (10.1016/j.ejpb.2010.03.019)
• Lau, W. M., White, A. W., Donaldson, M. and Heard, C. M. 2010. Histochemical visualisation of esterase activity in porcine ear skin. Journal of Pharmacy and Pharmacology 62(6), pp. 798-798. (10.1211/jpp.62.06.0016)
• Searby, C., Heard, C. M. and Porter, R. M. 2010. Sonic hedgehog is not enough to create basal cell carcinoma in vitro. British Journal of Dermatology 162(4), pp. 923-923. (10.1111/j.1365-2133.2010.09700.x)
• Abdelouahab, N. and Heard, C. M. 2010. Estimation of the Relative Antiinflammatory Efficacies of Six Commercial Preparations of Harpagophytum procumbens (Devil's Claw). Phytotherapy Research 24(3), pp. 333-338. (10.1002/ptr.2930)
• Ballam, L. and Heard, C. M. 2010. Pre-Treatment with Aloe vera Juice Does Not Enhance the in vitro Permeation of Ketoprofen across Skin. Skin Pharmacology and Physiology 23(2), pp. 113-116. (10.1159/000265682)
• Lee, L. M., Davison, Z. and Heard, C. M. 2010. In vitro delivery of anti-breast cancer agents directly via the mammary papilla (nipple). International Journal of Pharmaceutics 387(1-2), pp. 161-166. (10.1016/j.ijpharm.2009.12.021)
• Zulfakar, M. H., Abdelouahab, N. and Heard, C. M. 2010. Enhanced topical delivery and ex vivo anti-inflammatory activity from a betamethasone dipropionate formulation containing fish oil. Inflammation Research 59(1), pp. 23-30. (10.1007/s00011-009-0065-z)
• Lau, W. M., White, A. W. and Heard, C. M. 2010. Topical delivery of a naproxen-dithranol co-drug: in vitro skin penetration, permeation, and staining. Pharmaceutical Research 27(12), pp. 2734-2742. (10.1007/s11095-010-0274-8)
• Samah, N. A., Williams, N. and Heard, C. M. 2010. Nanogel particulates located within diffusion cell receptor phases following topical application demonstrates uptake into and migration across skin. International Journal of Pharmaceutics 401(1-2), pp. 72-78. (10.1016/j.ijpharm.2010.08.011)

2009

• Davison, Z., Nicholson, R. I., Maillard, J., Denyer, S. P. and Heard, C. M. 2009. Control of microbial contamination of Franz diffusion cell receptor phase in the development of transcutaneous breast cancer therapeutics. Letters in Applied Microbiology 49(4), pp. 456-460. (10.1111/j.1472-765X.2009.02685.x)
• Abdelouahab, N. and Heard, C. M. 2009. A novel ex vivo skin model for the assessment of the potential transcutaneous anti-inflammatory effect of topically applied Harpagophytum procumbens extract. International Journal of Pharmaceutics 376(1-2), pp. 63-68. (10.1016/j.ijpharm.2009.04.017)
• Davison, Z., Nicholson, R. I., Maillard, J. Y., Denyer, S. P. and Heard, C. M. 2009. Control of microbial contamination of Franz diffusion cell receptor phase in the development of transcutaneous breast cancer therapeutics. Letters In Applied Microbiology 49(4), pp. 456-460. (10.1111/j.1472-765X.2009.02685.x)
• Morris, A. P., Brain, K. R. and Heard, C. M. 2009. Skin permeation and ex vivo skin metabolism of O-acyl haloperidol ester prodrugs. International Journal of Pharmaceutics 367(1-2), pp. 44-50. (10.1016/j.ijpharm.2008.09.013)
• Ong, C. M. Y. and Heard, C. M. 2009. Permeation of quinine across sublingual mucosa, in vitro. International Journal of Pharmaceutics 366(1-2), pp. 58-64. (10.1016/j.ijpharm.2008.08.048)

2008

• Davison, Z., Dutkowski, C. M., Gee, J. M. W., Nicholson, R. I. and Heard, C. M. 2008. In vitro effects on MCF-7 breast cancer cells of signal transduction inhibitor/tamoxifen/eicosapentaenoic acid combinations and their simultaneous delivery across skin. Pharmaceutical Research 25(11), pp. 2516-2525. (10.1007/s11095-008-9665-5)
• Elgorashi, A. S., Heard, C. M., Niazy, E. M., Noureldin, O. H. and Pugh, W. J. 2008. Transdermal delivery enhancement of haloperidol from gel formulations by 1,8-cineole. Journal of Pharmacy and Pharmacology 60(6), pp. 689-692. (10.1211/jpp.60.6.0002)
• Abdelouahab, N. and Heard, C. M. 2008. Effect of the major glycosides of Harpagophytum procumbens (Devil's Claw) on epidermal cyclooxygenase-2 (COX-2) in vitro. Journal of Natural Products 71(5), pp. 746-749. (10.1021/np070204u)
• Abdelouahab, N. and Heard, C. M. 2008. Dermal and transcutaneous delivery of the major glycoside constituents of Harpagophytum procumbens (Devil's Claw) in vitro. Planta Medica 74(5), pp. 527-531. (10.1055/s-2008/1074500)
• Abdulmajed, K. and Heard, C. . M. 2008. Topical delivery of retinyl ascorbate. Skin Pharmacology and Physiology 21(1), pp. 46-49. (10.1159/000111135)
• Heard, C. M. and Screen, C. 2008. Probing the permeation enhancement of mefenamic acid by ethanol across full-thickness skin, heat-separated epidermal membrane and heat-separated dermal membrane. International Journal of Pharmaceutics 349(1-2), pp. 323-325. (10.1016/j.ijpharm.2007.08.006)
• Lau, W. M., White, A. W., Gallagher, S. J., Donaldson, M., McNaughton, G. and Heard, C. M. 2008. Scope and limitations of the co-drug approach to topical drug delivery. Current Pharmaceutical Design 14(8), pp. 794-802.
• Morris, A., Brain, K. R. and Heard, C. M. 2008. Synthesis of haloperidol prodrugs and their hydrolysis by porcine liver esterase. Drug Metabolism Letters 2(4), pp. 275-279. (10.2174/187231208786734111)

2007

• Heard, C. M. and Thomas, C. P. 2007. Probing the skin permeation of eicosapentaenoic acid and ketoprofen 2. Comparative depth profiling and metabolism of eicosapentaenoic acid. European Journal of Pharmaceutics and Biopharmaceutics 67(1), pp. 156-165. (10.1016/j.ejpb.2006.11.024)
• Cole, L. and Heard, C. M. 2007. Skin permeation enhancement potential of aloe vera and a proposed mechanism of action based upon size exclusion and pull effect. International Journal of Pharmaceutics 333(1-2), pp. 10-16. (10.1016/j.ijpharm.2006.09.047)
• Thomas, C. P., Davison, Z. and Heard, C. M. 2007. Probing the skin permeation of fish oil/EPA and ketoprofen-3. Effects on epidermal COX-2 and LOX. Prostaglandins Leukotrienes & Essential Fatty Acids 76(6), pp. 357-362. (10.1016/j.plefa.2007.05.002)
• Thomas, C. P. and Heard, C. M. 2007. Probing the skin permeation of eicosapentaenoic acid and ketoprofen - 2. Comparative depth profiling and metabolism of eicosapentaenoic acid. European Journal of Pharmaceutics and Biopharmaceutics 67(1), pp. 156-165. (10.1016/j.ejpb.2006.11.024)
• Thomas, C. P., Platts, J. A., Tatchell, T. and Heard, C. M. 2007. Probing the skin permeation of fish oil/EPA and ketoprofen 1. NMR spectroscopy and molecular modelling. International Journal of Pharmaceutics 338(1-2), pp. 207-212. (10.1016/j.ijpharm.2007.02.006)
• Zulfakar, M. H., Edwards, M. and Heard, C. M. 2007. Is there a role for topically delivered eicosapentaenoic acid in the treatment of psoriasis?. European Journal of Dermatology 17(4), pp. 284-291. (10.1684/ejd.2007.0201)

2006

• Heard, C. M., Johnson, S., Moss, G. and Thomas, C. P. 2006. In vitro transdermal delivery of caffeine, theobromine, theophylline and catechin from extract of Guarana, Paullinia Cupana. International Journal of Pharmaceutics 317(1), pp. 26-31. (10.1016/j.ijpharm.2006.02.042)
• Richards, H., Thomas, C. P., Bowen, J. L. and Heard, C. M. 2006. In-vitro transcutaneous delivery of ketoprofen and polyunsaturated fatty acids from a pluronic lecithin organogel vehicle containing fish oil. African Journal of Pharmacy and Pharmacology 58(7), pp. 903-908. (10.1211/jpp.58.7.0004)
• Bowen, J. L. and Heard, C. M. 2006. Film drying and complexation effects in the simultaneous skin permeation of ketoprofen and propylene glycol from simple gel formulations. International Journal of Pharmaceutics 307(2), pp. 251-257. (10.1016/j.ijpharm.2005.10.014)
• Abdulmajed, K., McGuigan, C. and Heard, C. M. 2006. Topical delivery of retinyl ascorbate co-drug. 5. in vitro degradation studies. Skin Pharmacology and Physiology 19(5), pp. 248-258. (10.1159/000093980)

2005

• Abdulmajed, K., McGuigan, C. and Heard, C. M. 2005. Topical delivery of retinyl ascorbate co-drug: 6. determination of toxic dose and antioxidant activity in cultured human epidermal keratinocytes. Die Pharmazie - An International Journal of Pharmaceutical Sciences, 60(10), pp. 794-795.
• Heard, C. M. et al. 2005. Preferential π–π complexation between tamoxifen and borage oil/γ linolenic acid: transcutaneous delivery and NMR spectral modulation. International Journal of Pharmaceutics 302(1-2), pp. 47-55. (10.1016/j.ijpharm.2005.06.013)
• Heard, C. M., Abdulmajed, K. and McCuigan, C. 2005. Topical delivery of retinyl ascorbate co-drug: 4. Comparative anti-oxidant activity towards DPPH. Free Radical Research 39(5), pp. 491-498. (10.1080/10715760500072263)
• Abdulmajed, K., McGuigan, C. and Heard, C. M. 2005. Topical delivery of retinyl ascorbate: 4. comparative anti-oxidant activity towards DPPH. Free Radical Research 39(5), pp. 491-498. (10.1080/10715760500072263)
• Chilcott, R. P. et al. 2005. Inter- and intralaboratory variation of in vitro diffusion cell measurements: an international multicenter study using quasi-standardized methods and materials. Journal of Pharmaceutical Sciences 94(3), pp. 632-638. (10.1002/jps.20229)
• Thomas, C. P. and Heard, C. M. 2005. In vitro transcutaneous delivery of ketoprofen and essential polyunsaturated fatty acids from a fish oil vehicle incorporating 1,8-cineole. Drug Delivery 12(1), pp. 7-14. (10.1080/10717540590889565)
• Gallagher, S. J. and Heard, C. M. 2005. Solvent content and macroviscosity effects on the in vitro transcutaneous delivery and skin distribution of ketoprofen from simple gel formulations. Skin Pharmacology and Physiology 18(4), pp. 186-194. (10.1159/000085864)

2004

• Ho, S., Calder, R. J., Thomas, C. P. and Heard, C. M. 2004. In-vitro transcutaneous delivery of tamoxifen and γ-linolenic acid from borage oil containing ethanol and 1,8-cineole. Pharmacy and Pharmacology 56(11), pp. 1357-1364. (10.1211/0022357044599)
• Abdulmajed, K., Heard, C. M., McGuigan, C. and Pugh, W. J. 2004. Topical delivery of retinyl ascorbate co-drug - 2. Comparative skin tissue and keratin binding studies. Skin Pharmacology and Physiology 17(6), pp. 274-282. (10.1159/000081112)
• Batchelder, R. J., Calder, R. J., Thomas, C. P. and Heard, C. M. 2004. In vitro transdermal delivery of the major catechins and caffeine from extract of Camellia sinensis. International Journal of Pharmaceutics 283(1-2), pp. 45-51. (10.1016/j.ijpharm.2004.06.007)
• Abdulmajed, K. and Heard, C. M. 2004. Topical delivery of retinyl ascorbate co-drug - 1. synthesis, penetration into and permeation across human skin. International Journal of Pharmaceutics 280(1-2), pp. 113-124. (10.1016/j.ijpharm.2004.05.008)
• Heard, C. M., Jarvis, C. A. and McGuigan, C. 2004. In vitro delivery of novel, highly potent anti-varicella zoster virus nucleoside analogues to their target site in the skin. Pharmaceutical Research 21(6), pp. 914-919. (10.1023/B:PHAM.0000029277.60760.43)
• Karia, C., Harwood, J. L., Morris, A. and Heard, C. M. 2004. Simultaneous permeation of tamoxifen and gamma linolenic acid across excised human skin. Further evidence of the permeation of solvated complexes. International Journal of Pharmaceutics 271(1-2), pp. 305-309. (10.1016/j.ijpharm.2003.11.017)

2003

• Gallagher, S. J., Trottet, L. and Heard, C. M. 2003. Ketoprofen: release from, permeation across and rheology of simple gel formulations that simulate increasing dryness. International Journal of Pharmaceutics 268(1-2), pp. 37-45. (10.1016/j.ijpharm.2003.08.012)
• Heard, C. M., Gallagher, S. J., Harwood, J. L. and Maguire, P. B. 2003. The in vitro delivery of NSAIDS across skin was in proportion to the delivery of essential fatty acids in the vehicle - evidence that solutes permeate skin associated with their solvation cages?. International Journal of Pharmaceutics 261(1-2), pp. 165-169. (10.1016/S0378-5173(03)00297-7)
• Aboul-Enein, H. Y., El-Awady, M. I. and Heard, C. M. 2003. Enantiomeric resolution of some 2-arylpropionic acids using L(-)-serine-impregnated silica as stationary phase by thin layer chromatography. Journal of Pharmaceutical and Biomedical Analysis 32(4-5), pp. 1055-1059. (10.1016/S0731-7085(03)00208-5)
• Jarvis, C. A., Heard, C. M. and McGuigan, C. 2003. Targeted dermal delivery of highly potent anti-varicella zoster virus nucleoside analogues from saturated solutions and ethanolic oil-in-water creams. Journal of drug targeting 11(7), pp. 433-441. (10.1080/1061186042000201990)
• Aboul-Enein, H. Y., El-Awady, M. I. and Heard, C. M. 2003. Thin layer chromatographic resolution of some 2-arylpropionic acid enantiomers using L-(-)-serine, L-(-)-threonine and a mixture of L-(-)-serine and L-(-)threonine-impregnated silica gel as stationary phases. Biomedical Chromatography 17(5), pp. 325-334. (10.1002/bmc.245)
• Gallagher, S. J., Trottet, L., Carter, T. P. and Heard, C. M. 2003. Effects of membrane type and liquid/liquid phase boundary on in vitro release of ketoprofen from gel formulations. Journal of drug targeting 11(6), pp. 373-379. (10.1080/10611860310001636890)
• Heard, C. M., Monk, B. and Modley, A. J. 2003. Binding of primaquine to epidermal membranes and keratin. International Journal of Pharmaceutics 257(1-2), pp. 237-244. (10.1016/S0378-5173(03)00140-6)
• Jarvis, C., McGuigan, C. and Heard, C. M. 2003. Penetration of highly active anti-VZV nucleoside analogues into and through full-thickness skin. Antiviral Research 57(3), pp. A68-A68.

2002

• Banning, T. P. and Heard, C. M. 2002. Binding of doxycycline to keratin, melanin and human epidermal tissue. International Journal of Pharmaceutics 235(1-2), pp. 219-227. (10.1016/S0378-5173(01)00988-7)
• Chedgzoy, P., Winckle, G. and Heard, C. M. 2002. Triclosan: release from transdermal adhesive formulations and in vitro permeation across human epidermal membranes. International Journal of Pharmaceutics 235(1-2), pp. 229-236. (10.1016/S0378-5173(01)00992-9)
• Aboul-Enein, H. Y., El-Awady, M. I. and Heard, C. M. 2002. Direct enantiomeric resolution of some cardiovascular agents using synthetic polymers imprinted with (-)-S-timolol as chiral stationary phase by thin layer chromatography. Die Pharmazie - An International Journal of Pharmaceutical Sciences, 57(3), pp. 169-171.

2000

• Allender, C. J., Richardson, C., Woodhouse, B., Heard, C. M. and Brain, K. R. 2000. Pharmaceutical applications for molecularly imprinted polymers. International Journal of Pharmaceutics 195(1-2), pp. 39-43. (10.1016/S0378-5173(99)00355-5)
• Aboul-Enein, H. Y., El-Awady, M. I. and Heard, C. M. 2000. Enantiomeric separation of aminoglutethimide, acetyl aminoglutethimide, and dansyl aminoglutethimide by tlc with beta-cyclodextrin and derivatives as mobile phase additives. Journal of Liquid Chromatography and Related Technologies 23(17), pp. 2715-2726. (10.1081/JLC-100101829)

1999

• Aboul-Enein, H. Y., El-Awady, M. I., Heard, C. M. and Nicholls, P. J. 1999. Application of thin-layer chromatography in enantiomeric chiral analysis - an overview. Biomedical Chromatography 13(8), pp. 531-537. (10.1002/(SICI)1099-0801(199912)13:8<531::AID-BMC921>3.0.CO;2-Q)
• Perkins, N. C. and Heard, C. M. 1999. In vitro dermal and transdermal delivery of doxycycline from ethanol/migliol 840 vehicles. International Journal of Pharmaceutics 190(2), pp. 155-164. (10.1016/S0378-5173(99)00240-9)
• Jeans, C. W. and Heard, C. M. 1999. A therapeutic dose of primaquine can be delivered across excised human skin from simple transdermal patches. International Journal of Pharmaceutics 189(1), pp. 1-6. (10.1016/S0378-5173(99)00215-X)
• Suedee, R., Brain, K. R. and Heard, C. M. 1999. Differential permeation of propranolol enantiomers across human skin in vitro from formulations containing an enantioselective excipient. Chirality -New York- 11(9), pp. 680-683. (10.1002/(SICI)1520-636X(1999)11:9<680::AID-CHIR2>3.0.CO;2-B)

1997

• Allender, C. J., Heard, C. M. and Brain, K. R. 1997. Mobile phase effects on enantiomer resolution using molecularly imprinted polymers. Chirality -New York- 9(3), pp. 238-242. (10.1002/(SICI)1520-636X(1997)9:3<238::AID-CHIR6>3.0.CO;2-B)
• Allender, C. J., Brain, K. R. and Heard, C. M. 1997. Binding cross-reactivity of Boc-phenylalanine enantiomers on molecularly imprinted polymers. Chirality -New York- 9(3), pp. 233-237. (10.1002/(SICI)1520-636X(1997)9:3<233::AID-CHIR5>3.0.CO;2-G)
• Suedee, R., Brain, K. R. and Heard, C. M. 1997. Enantioselective retardation of rac-propranolol from matrices containing cellulose derivatives. Chirality -New York- 9(3), pp. 307-312. (10.1002/(SICI)1520-636X(1997)9:3<307::AID-CHIR18>3.0.CO;2-R)
• Suedee, R. and Heard, C. M. 1997. Direct resolution of propranolol and bupranolol by thin-layer chromatography using cellulose derivatives as stationary phase. Chirality -New York- 9(2), pp. 139-144. (10.1002/(SICI)1520-636X(1997)9:2<139::AID-CHIR11>3.0.CO;2-O)

1996

• Heard, C. M. and Suedee, R. 1996. Stereoselective adsorption and trans-membrane transfer of propranolol enantiomers using cellulose derivatives. International Journal of Pharmaceutics 139(1-2), pp. 15-23. (10.1016/0378-5173(96)04564-4)
• Heard, C. M. and Hadgraft, J. 1996. Ion-pairing interactions between 99mTc-based myocardial imaging agents and oleic acid. Pharmaceutical Research 13(2), pp. 316-323.

1995

• Heard, C. M. and Brain, K. R. 1995. Does solute stereochemistry influence percutaneous penetration?. Chirality -New York- 7(4), pp. 305-309.

1993

• Heard, C. M., Watkinson, A. C., Brain, K. R. and Hadgraft, J. 1993. Invitro skin penetration of propranolol enantiomers. International Journal of Pharmaceutics 90(3), pp. R5-R8. (10.1016/0378-5173(93)90202-Q)