Yr Athro James Birchall

2021

• Gualeni, B.et al. 2021. Human-centred design of a new microneedle-based hormonal contraceptive delivery system [version 2; peer review: 2 approved with reservations]. Gates Open Research 5, article number: 96. (10.12688/gatesopenres.13233.2)
• Nishio Ayre, W.et al. 2021. Alternative radiopacifiers for polymethyl methacrylate bone cements: Silane-treated anatase titanium dioxide and yttria-stabilised zirconium dioxide. Journal of Biomaterials Applications 35(10), pp. 1235-1252. (10.1177/0885328220983797)
• Singh, R. K.et al. 2021. Using gold nanoparticles for enhanced intradermal delivery of poorly soluble auto-antigenic peptides. Nanomedicine: Nanotechnology, Biology and Medicine 32, article number: 102321. (10.1016/j.nano.2020.102321)
• Ingrole, R. S.et al. 2021. Trends of microneedle technology in the scientific literature, patents, clinical trials and internet activity. Biomaterials 267, article number: 120491. (10.1016/j.biomaterials.2020.120491)
• Tyrrell, V. J.et al. 2021. Lipidomic and transcriptional analysis of the Linoleoyl-omega-Hydroxyceramide biosynthetic pathway in human psoriatic lesions. Journal of Lipid Research 62, article number: 100094. (10.1016/j.jlr.2021.100094)

2020

• Bolton, C. J. W.et al. 2020. Hollow silicon microneedle fabrication using advanced plasma etch technologies for applications in transdermal drug delivery. Lab on a Chip 20(15), pp. 2788-2795. (10.1039/D0LC00567C)
• Arikat, F.et al. 2020. Targeting proinsulin to local immune cells using an intradermal microneedle delivery system; a potential antigen-specific immunotherapy for type 1 diabetes. Journal of Controlled Release 322, pp. 593-601. (10.1016/j.jconrel.2020.02.031)

2019

• Maarifi, G.et al. 2019. Langerin (CD207) represents a novel interferon-stimulated gene in Langerhans cells. Cellular and Molecular Immunology 17, pp. 547-549. (10.1038/s41423-019-0302-5)
• Dul, M.et al. 2019. Conjugation of a peptide autoantigen to gold nanoparticles for intradermally administered antigen specific immunotherapy. International Journal of Pharmaceutics 562, pp. 303-312. (10.1016/j.ijpharm.2019.03.041)

2018

• Price, A.et al. 2018. Topical propranolol for infantile haemangiomas: A systematic review. Journal of the European Academy of Dermatology and Venereology 32(12), pp. 2083-2089. (10.1111/jdv.14963)
• Gualeni, B.et al. 2018. Minimally-invasive and targeted therapeutic cell delivery to the skin using microneedle devices. British Journal of Dermatology 178(3), pp. 731-739. (10.1111/bjd.15923)
• Davies, L.et al. 2018. Accelerating topical anaesthesia using microneedles. Skin Pharmacology and Physiology 30(6), pp. 277-283. (10.1159/000479530)

2017

• Moreno, E.et al. 2017. Skin vaccination using microneedles coated with a plasmid DNA cocktail encoding nucleosomal histones of Leishmania spp.. International Journal of Pharmaceutics 533(1), pp. 236-244. (10.1016/j.ijpharm.2017.09.055)
• Dul, M.et al. 2017. Hydrodynamic gene delivery in human skin using a hollow microneedle device. Journal of Controlled Release 265, pp. 120-131. (10.1016/j.jconrel.2017.02.028)
• Zhao, X.et al. 2017. Formulation of hydrophobic peptides for skin delivery via coated microneedles. Journal of Controlled Release 265, pp. 2-13. (10.1016/j.jconrel.2017.03.015)
• McGrath, M.et al. 2017. Editorial. Journal of Controlled Release 265, pp. 1-1. (10.1016/j.jconrel.2017.10.030)
• Martin, C.et al. 2017. Development and evaluation of topical gabapentin formulations. Pharmaceutics 9(3), pp. 31. (10.3390/pharmaceutics9030031)
• Jones, B.et al. 2017. Imaging techniques for dry powder inhaler capsules. Inhalation

2016

• Nishio Ayre, W.et al. 2016. A novel liposomal drug delivery system for PMMA bone cements. Journal of Biomedical Materials Research Part B: Applied Biomaterials 104(8), pp. 1510-1524. (10.1002/jbm.b.33488)
• Czubala, M. A.et al. 2016. TGFβ induces a SAMHD1-independent post-entry restriction to HIV-1 infection of human epithelial Langerhans cells. Journal of Investigative Dermatology 136(10), pp. 1981-1989. (10.1016/j.jid.2016.05.123)
• Caucheteux, S. M.et al. 2016. Polypropylene sulfide nanoparticle p24 vaccine promotes dendritic cell-mediated specific immune responses against HIV-1. Journal of Investigative Dermatology 136(6), pp. 1172-1181. (10.1016/j.jid.2016.01.033)
• Teagle, A. R., Birchall, J. C. and Hargest, R. 2016. Gene therapy for pyoderma gangrenosum: optimal transfection conditions and effect of drugs on gene delivery in the HaCaT cell line using cationic liposomes. Skin Pharmacology and Physiology 29, pp. 119-129. (10.1159/000444859)
• Chong, R. H.et al. 2016. Evaluating the sensitivity, reproducibility and flexibility of a method to test hard shell capsules intended for use in dry powder inhalers. International Journal of Pharmaceutics 500(1-2), pp. 316-325. (10.1016/j.ijpharm.2016.01.034)
• Zhao, X.et al. 2016. Microneedle delivery of autoantigen for immunotherapy in type 1 diabetes. Journal of Controlled Release 223, pp. 178-187. (10.1016/j.jconrel.2015.12.040)

2015

• Alhadj Ali, M.et al. 2015. Topical steroid therapy induces pro-tolerogenic changes in Langerhans cells in human skin. Immunology 146(3), pp. 411-422. (10.1111/imm.12518)
• Choi, H.et al. 2015. Design and in vitro interference test of microwave noninvasive blood glucose monitoring sensor. IEEE Transactions on Microwave Theory and Techniques 63(10), pp. 3016-3025. (10.1109/TMTT.2015.2472019)
• Ivory, M. O., Birchall, J. C. and Piguet, V. 2015. Early dengue virus infection in human skin: a cycle of inflammation and infectivity [Commentary]. Journal of Investigative Dermatology 135(7), pp. 1711-1712. (10.1038/jid.2014.544)

2014

• Rattanapak, T.et al. 2014. Dynamic visualization of dendritic cell-antigen interactions in the skin following transcutaneous immunization. PLOS ONE 9(2), article number: e89503. (10.1371/journal.pone.0089503)

2013

• Rattanapak, T.et al. 2013. Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using Optical Coherence Tomography and Two-Photon Microscopy. Journal of Controlled Release 172(3), pp. 894-903. (10.1016/j.jconrel.2013.08.018)
• Pearton, M.et al. 2013. Host responses in human skin after conventional intradermal injection or microneedle administration of virus-like-particle influenza vaccine. Advanced Healthcare Materials 2(10), pp. 1401-1410. (10.1002/adhm.201300006)
• Chong, R.et al. 2013. Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept. Journal of Controlled Release 166(3), pp. 211-219. (10.1016/j.jconrel.2012.12.030)
• Tatovic, D.et al. 2013. Topical steroid has the potential of modulating skin dendritic cells to tolerogenic antigen presenting cells in human organ skin bath culture [Abstract]. Diabetic Medicine 30(s1), pp. 53-53. (10.1111/dme.12091_1)
• Groves, R. B.et al. 2013. An anisotropic, hyperelastic model for skin: experimental measurements, finite element modelling and identification of parameters for human and murine skin. Journal of the Mechanical Behaviour of Biomedical Materials 18, pp. 167-180. (10.1016/j.jmbbm.2012.10.021)
• Torrisi, B. M.et al. 2013. Pocketed microneedles for rapid delivery of a liquid-state botulinum toxin A formulation into human skin. Journal of Controlled Release 165(2), pp. 146-152. (10.1016/j.jconrel.2012.11.010)
• Torrisi, B. M.et al. 2013. The development of a sensitive methodology to characterise hard shell capsule puncture by dry powder inhaler pins. International Journal of Pharmaceutics 456(2), pp. 545-552. (10.1016/j.ijpharm.2013.08.011)
• Chong, R. H.et al. 2013. Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept. Journal of Controlled Release 166(3), pp. 211. (10.1016/j.jconrel.2012.12.030)

2012

• Yildiz, A.et al. 2012. Inhaled extended-release microparticles of heparin elicit improved pulmonary pharmacodynamics against antigen-mediated airway hyper-reactivity and inflammation. Journal of Controlled Release 162(2), pp. 456-463. (10.1016/j.jconrel.2012.07.008)
• Birchall, J. C. 2012. Overcoming the stratum corneum barrier: microneedle delivery of macromolecules and vaccines [Abstract]. International Journal of Cosmetic Science 34(4), pp. 361-361. (10.1111/j.1468-2494.2012.00720.x)
• Pearton, M.et al. 2012. Microneedle delivery of plasmid DNA to living human skin: Formulation coating, skin insertion and gene expression. Journal of Controlled Release 160(3), pp. 561-569. (10.1016/j.jconrel.2012.04.005)
• Martin, C.et al. 2012. Low temperature fabrication of biodegradable sugar glass microneedles for transdermal drug delivery applications. Journal of Controlled Release 158(1), pp. 93-101. (10.1016/j.jconrel.2011.10.024)
• Groves, R. B.et al. 2012. Quantifying the mechanical properties of human skin to optimise future microneedle device design. Computer Methods in Biomechanics and Biomedical Engineering 15(1), pp. 73-82. (10.1080/10255842.2011.596481)

2011

• Gonzalez-Gonzalez, E.et al. 2011. Visualization of plasmid delivery to keratinocytes in mouse and human epidermis. Scientific Reports 1, pp. 158. (10.1038/srep00158)
• Chong, R.et al. 2011. Nucleic acid delivery to skin for the potential treatment of dermatopathogenic conditions [Abstract]. Human Gene Therapy 22(10), pp. A82-A82.
• Teagle, A., Birchall, J. C. and Hargest, R. 2011. The effect of drugs commonly used for pyoderma gangrenosum on the efficiency of gene transfer to human keratinocytes. Human Gene Therapy 22(10), pp. A94-A94.
• Smith, M. W., Birchall, J. C. and Coulman, S. 2011. The wider contribution of microbiology to the pharmaceutical sciences. In: Denver, S. P. et al. eds. Hugo and Russell's Pharmaceutical Microbiology 8th Edition. Wiley-Blackwell, pp. 463-482.
• Teagle, A., Birchall, J. C. and Hargest, R. 2011. The effect of drugs commonly used for pyoderma gangrenosum on the efficiency of gene transfer to human keratinocytes [Abstract]. British Journal of Surgery 98, pp. 40-40. (10.1002/bjs.7577/abstract)
• Birchall, J. C.et al. 2011. Microneedles in clinical practice- an exploratory study into the opinions of healthcare professionals and the public. Pharmaceutical Research 28(1), pp. 95-106. (10.1007/s11095-010-0101-2)
• Coulman, S.et al. 2011. In vivo, in situ imaging of microneedle insertion into the skin of human volunteers using optical coherence tomography. Pharmaceutical Research 28(1), pp. 66-81. (10.1007/s11095-010-0167-x)
• Groves, R. B.et al. 2011. Using inverse finite element modeling to identify the anisotropic mechanical properties of human and mouse skin in tension. Presented at: International Conference on the Mechanics of Biomaterials and Tissues, Hawaii, USA, 11-15 December 2011.

2010

• Pearton, M.et al. 2010. Immune stimulation following microneedle delivery of influenza virus-like particle (VLP) vaccines to human skin [Abstract]. Drug Discovery Today 15(23-24), pp. 1111-1111.
• Song, J. M.et al. 2010. Microneedle delivery of H5N1 influenza virus-like particles to the skin induces long-lasting B- and T-Cell responses in mice. Clinical and Vaccine Immunology 17(9), pp. 1381-1389. (10.1128/CVI.00100-10)
• Pearton, M.et al. 2010. Influenza virus-like particles coated onto microneedles can elicit stimulatory effects on Langerhans cells in human skin. Vaccine 28(37), pp. 6104-6113. (10.1016/j.vaccine.2010.05.055)
• Pearton, M.et al. 2010. Changes in human Langerhans cells following intradermal injection of influenza virus-like particle vaccines. PLoS ONE 5(8), article number: e12410. (10.1371/journal.pone.0012410)
• Bains, B. K.et al. 2010. In vitro reporter gene transfection via plasm ID DNA delivered by metered dose inhaler. Journal of Pharmaceutical Sciences 99(7), pp. 3089-3099. (10.1002/jps.22085)
• Martin, C.et al. 2010. Biodegradable sugar glass microneedles for macromolecular drug delivery [Abstract]. Journal of Pharmacy and Pharmacology 62(6), pp. 799-799. (10.1211/jpp.62.06.0016)
• Ng, K. W.et al. 2010. Biodegradable microneedles for intra-epidermal vaccination [Abstract]. Journal of Pharmacy and Pharmacology 62(6), pp. 798-798. (10.1211/jpp.62.06.0016)

2009

• Ng, K. W.et al. 2009. Development of an ex vivo human skin model for intradermal vaccination: Tissue viability and Langerhans cell behaviour. Vaccine 27(43), pp. 5948-5955. (10.1016/j.vaccine.2009.07.088)
• Ng, K. W.et al. 2009. Tissue viability and Langerhans cell behaviour in an ex-vivo human skin model for cutaneous DNA vaccination [Abstract]. Journal of Pharmacy and Pharmacology 61(S1), pp. A1-A5. (10.1211/002235709789037044)
• Coulman, S.et al. 2009. Microneedle mediated delivery of nanoparticles into human skin. International Journal of Pharmaceutics 366(1-2), pp. 190-200. (10.1016/j.ijpharm.2008.08.040)
• Haq, M.et al. 2009. Penetration and wound-healing responses following application of microneedles and hypodermic needles to human volunteers. Journal of Pharmacy and Pharmacology 61(S1)
• Haq, M. I.et al. 2009. Clinical administration of microneedles: skin puncture, pain and sensation. Biomedical Microdevices 11(1), pp. 35-47. (10.1007/s10544-008-9208-1)
• Ng, K. W.et al. 2009. Ex vivo immunological studies using excised human skin. British Journal Of Dermatology 160(4), pp. 921-921.

2008

• Pearton, M.et al. 2008. Gene delivery to the epidermal cells of human skin explants using microfabricated microneedles and hydrogel formulations. Pharmaceutical Research 25(2), pp. 407-416. (10.1007/s11095-007-9360-y)
• Birchall, J. C., Jones, B. and Morrissey, A. 2008. A comparison of the puncturing properties of gelatin and hypromellose capsules for use in dry powder inhalers. Drug Development and Industrial Pharmacy 34(8), pp. 870-876. (10.1080/03639040801928903)

2007

• Bains, B. K.et al. 2007. Novel nanoparticles for pulmonary gene delivery [Abstract]. Pharmacy and Pharmacology 59(S1), pp. A31-A32. (10.1211/002235707781850140)
• Collins, E.et al. 2007. Nuclear localisation and pDNA condensation in non-viral gene delivery. The Journal of Gene Medicine 9(4), pp. 265-274. (10.1002/jgm.1015)
• Haq, M. I.et al. 2007. An assessment of pain, penetration efficiency and trans-epidermal water loss in human subjects following application of microfabricated microneedle arrays [Abstract]. Journal of Pharmacy and Pharmacology 59(S1), pp. A54. (10.1211/002235707781850168)
• Birchall, J. C. 2007. Pulmonary delivery of nucleic acids. Expert Opinion on Drug Delivery 4(6), pp. 575-578. (10.1517/17425247.4.6.575)
• Seville, P. C.et al. 2007. Amino acid-modified spray-dried powders with enhanced aerosolisation properties for pulmonary drug delivery. Powder Technology 178(1), pp. 40-50. (10.1016/j.powtec.2007.03.046)

2006

• Li, H. and Birchall, J. C. 2006. Chitosan-modified dry powder formulations for pulmonary gene delivery. Pharmaceutical Research 23(5), pp. 941-950. (10.1007/s11095-006-0027-x)
• Birchall, J. C.et al. 2006. Cutaneous gene expression of plasmid DNA in excised human skin following delivery via microchannels created by radio frequency ablation. International Journal of Pharmaceutics 312(1-2), pp. 15-23. (10.1016/j.ijpharm.2005.12.036)
• Coulman, S.et al. 2006. Minimally invasive cutaneous delivery of macromolecules and plasmid DNA via microneedles. Current drug delivery 3(1), pp. 65-75.
• Pearton, M.et al. 2006. Microneedle facilitated delivery of pDNA encoding HBsAg to human skin: potential for genetic vaccination [Abstract]. Journal of Pharmacy and Pharmacology 58(S1), pp. A65. (10.1211/002235706778251483)

2005

• Pearton, M.et al. 2005. Hydrogels based on PLGA-PEG-PLGA triblock co-polymers as sustained release reservoirs for the delivery of pDNA to microneedle treated human skin [Abstract]. Journal of Pharmacy and Pharmacology 57(S1), pp. S83-S84. (10.1211/002235705778248352)
• Li, H.et al. 2005. Nanoparticles for pulmonary drug delivery [Abstract]. Journal of Pharmacy and Pharmacology 57(S1), pp. S20. (10.1211/002235705778248569)
• Birchall, J. C.et al. 2005. Cutaneous DNA delivery and gene expression in ex vivo human skin explants via wet-etch microfabricated microneedles. Journal of drug targeting 13(7), pp. 415-421. (10.1080/10611860500383705)
• Li, H.et al. 2005. The use of absorption enhancers to enhance the dispersibility of spray-dried powders for pulmonary gene therapy. The Journal of Gene Medicine 7(8), pp. 1035-1043. (10.1002/jgm.749)

2004

• Coulman, S. A.et al. 2004. Microneedle facilitated cutaneous delivery of a non-viral gene complex to the viable epidermis [Abstract]. Journal of Pharmacy and Pharmacology 56(S1), pp. S10-S11. (10.1211/002235704777489375)
• Li, H.et al. 2004. Dispersibility of spray-dried formulations for pulmonary drug delivery [Abstract]. Journal of Pharmacy and Pharmacology 56(S1), pp. S10. (10.1211/002235704777489375)
• Birchall, J. C.et al. 2004. Microfabricated silicon microneedles for nonviral cutaneous gene delivery. British Journal of Dermatology 150(5), pp. 869-877. (10.1111/j.1365-2133.2004.05921.x)

2002

• Birchall, J. C., Kellaway, I. and Seville, P. 2002. Preparation of dry powder dispersions for non-viral gene delivery by freeze-drying and spray-drying. The Journal of Gene Medicine 4(4), pp. 428-437. (10.1002/jgm.282)

2001

• Birchall, J. C.et al. 2001. Statistical modelling of the formulation variables in non-viral gene delivery systems. Journal of Drug Targeting 9(3), pp. 169-184. (10.3109/10611860108997926)

2000

• Ramsay, E.et al. 2000. Examination of the biophysical interaction between plasmid DNA and the polycations, polylysine and polyornithine, as a basis for their differential gene transfection in-vitro. International Journal of Pharmaceutics 210(1-2), pp. 97-107. (10.1016/S0378-5173(00)00571-8)
• Birchall, J. C.et al. 2000. Gene expression in an intact ex-vivo skin tissue model following percutaneous delivery of cationic liposome-plasmid DNA complexes. International Journal of Pharmaceutics 197(1-2), pp. 233-238. (10.1016/S0378-5173(00)00336-7)
• Birchall, J. C., Kellaway, I. W. and Gumbleton, M. 2000. Physical stability and in-vitro gene expression efficiency of nebulised lipid-peptide-DNA complexes. International Journal of Pharmaceutics 197(1-2), pp. 221-231. (10.1016/S0378-5173(00)00339-2)