Yr Athro Andy Weightman
Head of Organisms and Environment Division, Professor
- weightman@cardiff.ac.uk
- +44 (0)29 2087 5877
- Cardiff School of Biosciences, Main Building, Museum Avenue, Cardiff, CF10 3AT, Adeilad Syr Martin Evans, Rhodfa'r Amgueddfa, Caerdydd, CF10 3AX
Trosolwg
Microbiomes, Microbes and Informatics
The Weightman group is part of the recently formed Microbiomes, Microbes and Informatics (MMI) group (webpage under development). The MMI group currently comprises the research groups of Thomas Connor, Esh Mahenthiralingam, Julian Marchesi and Andrew Weightman and has over 25 active research staff and postgraduate students.
The MMI group are highly research active generating over £3.5 million in grant income between 2010 and 2017, and publishing extensively in top journals (cumulative h index > 150, > 400 publications, and > 25,000; source Scopus.com).
The four current MMI staff recently moved (June 2017) to a single shared location within a new £1.6 million refurbished area of the Sir Martin Evans Building. This comprises a large class II certified research laboratory, equipment and tissue culture rooms, a group office area and academic offices. The MMI group welcomes approaches by potential fellowship applicants and funded PhD students to host their research and expand our strategic research on Microbiomes, Microbes and Informatics.
Cyhoeddiadau
2020
- Christofides, S. R.et al. 2020. The influence of migratory Paraburkholderia on growth and competition of wood-decay fungi. Fungal Ecology 45, article number: 100937. (10.1016/j.funeco.2020.100937)
- Cowle, M. W.et al. 2020. Impact of flow hydrodynamics and pipe material properties on biofilm development within drinking water systems. Environmental Technology 41(28), pp. 3732-3722. (10.1080/09593330.2019.1619844)
2019
- Christofides, S. R.et al. 2019. Fungal control of early-stage bacterial community development in decomposing wood. Fungal Ecology 42, article number: 100868. (10.1016/j.funeco.2019.100868)
- Roberts, M., Weightman, A. and Sapsford, D. J. 2019. Chapter 8. Potential application of direct and indirect iron bioreduction in resource recovery from iron oxide-bearing wastes. In: Macaskie, L., Sapsford, D. and Mayes, W. eds. Resource Recovery from Wastes: Towards a Circular Economy. , pp. 192-212., (10.1039/9781788016353-00192)
- Weiser, R.et al. 2019. Not all Pseudomonas aeruginosa are equal: strains from industrial sources possess uniquely large multireplicon genomes. Microbial Genomics, article number: 276. (10.1099/mgen.0.000276)
- Richardson, H.et al. 2019. Presence of mycobacterium avium subspecies paratuberculosis monitored over varying temporal and spatial scales in river catchments: persistent routes for human exposure. Microorganisms 7(5), article number: 136. (10.3390/microorganisms7050136)
- Webster, G.et al. 2019. Genome sequences of two choline-utilising methanogenic archaea, Methanococcoides spp., isolated from marine sediments. Microbiology Resource Announcements 8(18), article number: e00342-19. (10.1128/MRA.00342-19)
- Parkes, R. J.et al. 2019. Rock-crushing derived hydrogen directly supports a methanogenic community: significance for the deep biosphere.. Environmental Microbiology Reports 11(2), pp. 165-172. (10.1111/1758-2229.12723)
- Bird, J. T.et al. 2019. Uncultured microbial phyla suggest mechanisms for multi-thousand-year subsistence in Baltic Sea sediments. mBio 10(2), article number: e02376-18. (10.1128/mBio.02376-18)
- Drysdale, T.et al. 2019. Remote laboratories - Requirements capture for a national pooling infrastructure. Presented at: AdvanceHE STEM Teaching and Learning Conference 2019, Birmingham, UK, 30 -31 January 2019.
- Johnston, S.et al. 2019. Highly competitive fungi manipulate bacterial communities in decomposing beech wood (Fagus sylvativa). FEMS Microbiology Ecology 95(2) (10.1093/femsec/fiy225)
2017
- Roberts, M.et al. 2017. Changes in metal leachability through stimulation of iron reducing communities within waste sludge. Solid State Phenomena 262, pp. 269-272. (10.4028/www.scientific.net/SSP.262.269)
2016
- Johnston, S., Boddy, L. and Weightman, A. 2016. Bacteria in decomposing wood and their interactions with wood-decay fungi. FEMS Microbiology Ecology 92(11), article number: fiw179. (10.1093/femsec/fiw179)
- Nobu, M. K.et al. 2016. Phylogeny and physiology of candidate phylum 'Atribacteria' (OP9/JS1) inferred from cultivation-independent genomics. ISME Journal 10(2), pp. 273-286. (10.1038/ismej.2015.97)
- Durance, I.et al. 2016. The challenges of linking ecosystem services to biodiversity. Advances in Ecological Research 54, pp. 87-134. (10.1016/bs.aecr.2015.10.003)
- Roberts, M.et al. 2016. In situ microbial dissolution of iron mineral-bearing wastes for metal recovery. Presented at: 3rd International Symposium on Enhanced Landfill Mining, Lisbon, Portugal, February 2016.
2015
- Maceda-Veiga, A.et al. 2015. Chronic effects of temperature and nitrate pollution on Daphnia magna: Is this cladoceran suitable for widespread use as a tertiary treatment?. Water Research 83, pp. 141-152. (10.1016/j.watres.2015.06.036)
- Roussel, E. G. P.et al. 2015. Complex coupled metabolic and prokaryotic community responses to increasing temperatures in anaerobic marine sediments: critical temperatures and substrate changes. FEMS Microbiology Ecology 91(8), article number: fiv084. (10.1093/femsec/fiv084)
- Pass, D. A.et al. 2015. The effect of anthropogenic arsenic contamination on the earthworm microbiome. Environmental Microbiology 17(6), pp. 1884-1896. (10.1111/1462-2920.12712)
- O'Sullivan, L. A.et al. 2015. Survival of Desulfotomaculum spores from estuarine sediments after serial autoclaving and high-temperature exposure. ISME Journal 9, pp. 922-933. (10.1038/ismej.2014.190)
- Webster, G.et al. 2015. Archaeal community diversity and abundance changes along a natural salinity gradient in estuarine sediments. FEMS Microbiology Ecology 91(2), pp. 1-18. (10.1093/femsec/fiu025)
2014
- Rhodes, G.et al. 2014. Mycobacterium avium Subspecies paratuberculosis: Human Exposure through Environmental and Domestic Aerosols. Pathogens 3(3), pp. 577-595. (10.3390/pathogens3030577)
- Parkes, R. J.et al. 2014. A review of prokaryotic populations and processes in sub-seafloor sediments, including biosphere: geosphere interactions. Marine Geology 352, pp. 409-425. (10.1016/j.margeo.2014.02.009)
- Weiser, R.et al. 2014. Evaluation of five selective media for the detection of Pseudomonas aeruginosa using a strain panel from clinical, environmental and industrial sources. Journal of Microbiological Methods 99, pp. 8-14. (10.1016/j.mimet.2014.01.010)
- Vidal Quist, J.et al. 2014. Arabidopsis thaliana and Pisum sativum models demonstrate that root colonization is an intrinsic trait of Burkholderia cepacia complex bacteria. Microbiology 160(2), pp. 373-384. (10.1099/mic.0.074351-0)
- Parkes, R. J.et al. 2014. Studies on prokaryotic populations and processes in subseafloor sediments - an update. In: Kallmeyer, J. and Wagner, D. eds. Microbial Life of the Deep Biosphere. Berlin: de Gruyter, pp. 1-325.
- Wang, Y.et al. 2014. Bacterial diversity and community structure in high arsenic aquifers in Hetao Plain of Inner Mongolia, China. Geomicrobiology Journal 31(4), pp. 338-349. (10.1080/01490451.2013.835886)
2013
- O'Sullivan, L. A.et al. 2013. Contrasting relationships between biogeochemistry and prokaryotic diversity depth profiles along an estuarine sediment gradient. FEMS Microbiology Ecology 85(1), pp. 143-157. (10.1111/1574-6941.12106)
2012
- Gorra, R.et al. 2012. Dynamic microbial community associated with iron-arsenic co-precipitation products from a groundwater storage system in Bangladesh. Microbial Ecology 64(1), pp. 171-186. (10.1007/s00248-012-0014-1)
- Parkes, R. J.et al. 2012. Changes in methanogenic substrate utilization and communities with depth in a salt-marsh, creek sediment in southern England. Estuarine, Coastal and Shelf Science 96(1), pp. 170-178. (10.1016/j.ecss.2011.10.025)
2011
- White, J.et al. 2011. Culture-independent analysis of bacterial fuel contamination provides insight into the level of concordance with the standard industry practice of aerobic cultivation. Applied and Environmental Microbiology 77(13), pp. 4527-4538. (10.1128/AEM.02317-10)
- Webster, G.et al. 2011. Enrichment and cultivation of prokaryotes associated with the sulphate-methane transition zone of diffusion-controlled sediments of Aarhus Bay, Denmark under heterotrophic conditions. FEMS Microbiology Ecology 77(2), pp. 248-263. (10.1111/j.1574-6941.2011.01109.x)
- Parkes, R. J.et al. 2011. Prokaryotes stimulate mineral H2 formation for the deep biosphere and subsequent thermogenic activity. Geology 39(3), pp. 219-222. (10.1130/G31598.1)
- Rodrigues, C.et al. 2011. Microbial diversity in Frenulata (Siboglinidae, Polychaeta) species from mud volcanoes in the Gulf of Cadiz (NE Atlantic). Antonie van Leeuwenhoek 100(1), pp. 83-98. (10.1007/s10482-011-9567-0)
2010
- Rodrigues, C. F.et al. 2010. Chemosynthetic bacteria found in bivalve species from mud volcanoes of the Gulf of Cadiz. FEMS Microbiology Ecology 73(3), pp. 486-499. (10.1111/j.1574-6941.2010.00913.x)
- Webster, G.et al. 2010. Prokaryotic functional diversity in different biogeochemical depth zones in tidal sediments of the Severn Estuary, UK, revealed by stable-isotope probing. FEMS Microbiology Ecology 72(2), pp. 179-197. (10.1111/j.1574-6941.2010.00848.x)
- Parkes, R. J.et al. 2010. Methods for studying methanogens and methanogenesis in marine sediments. In: Timmis, K. H. ed. Handbook of Hydrocarbon and Lipid Microbiology., Vol. 5. Springer Reference Springer, pp. 3799-3827., (10.1007/978-3-540-77587-4_299)
- Dillon, R. J.et al. 2010. Diversity of gut microbiota increases with aging and starvation in the desert locust. Antonie van Leeuwenhoek International Journal of General and Molecular Microbiology 97(1), pp. 69-77. (10.1007/s10482-009-9389-5)
2009
- Parkes, R. J.et al. 2009. Culturable prokaryotic diversity of deep, gas hydrate sediments: First use of a continuous high-pressure, anaerobic, enrichment and isolation system for subseafloor sediments (DeepIsoBUG). Environmental Microbiology 11(12), pp. 3140-3153. (10.1111/j.1462-2920.2009.02018.x)
- Webster, G.et al. 2009. Subsurface microbiology and biogeochemistry of a deep, cold-water carbonate mound from the Porcupine Seabight (IODP Expedition 307). Environmental Microbiology 11(1), pp. 239-257. (10.1111/j.1462-2920.2008.01759.x)
- Fry, J. C.et al. 2009. Prokaryotic populations and activities in an interbedded coal deposit, including a previously deeply buried section (1.6–2.3 km) above ∼ 150 Ma basement rock. Geomicrobiology Journal 26(3), pp. 163-178. (10.1080/01490450902724832)
2008
- O'Sullivan, L. A.et al. 2008. Modified linker-PCR primers facilitate complete sequencing of DGGE DNA fragments. Journal of Microbiological Methods 75(3), pp. 579-581. (10.1016/j.mimet.2008.08.006)
- Fry, J. C.et al. 2008. Prokaryotic biodiversity and activity in the deep subseafloor biosphere. FEMS Microbiology Ecology 66(2), pp. 181-196. (10.1111/j.1574-6941.2008.00566.x)
- Schmidberger, J. W.et al. 2008. The crystal structure of DehI reveals a new α-haloacid dehalogenase fold and active-site mechanism. Journal of Molecular Biology 378(1), pp. 284-294. (10.1016/j.jmb.2008.02.035)
- Dillon, R. J.et al. 2008. Composition of Acridid gut bacterial communities as revealed by 16S rRNA gene analysis. Journal of Invertebrate Pathology 97(3), pp. 265-272. (10.1016/j.jip.2007.09.010)
- O'Sullivan, L. A.et al. 2008. Modified linker-PCR primers facilitate complete sequencing of DGGE DNA fragments. Journal of Microbiological Methods 75(3), pp. 579-581. (10.1016/j.mimet.2008.08.006)
- Schmidberger, J. W.et al. 2008. Purification, crystallization and preliminary crystallographic analysis of DehI, a group I alpha-haloacid dehalogenase from Pseudomonas putida strain PP3. Acta Crystallographica Section F: Structural Biology and Crystallization Communications 64(7), pp. 596-598. (10.1107/S1744309108008865)
2007
- Webster, G.et al. 2007. Distribution of candidate division JS1 and other Bacteria in tidal sediments of the German Wadden Sea using targeted 16S rRNA gene PCR-DGGE. FEMS Microbiology Ecology 62(1), pp. 78-89. (10.1111/j.1574-6941.2007.00372.x)
- Parkes, R. J.et al. 2007. Biogeochemistry and biodiversity of methane cycling in subsurface marine sediments (Skagerrak, Denmark). Environmental Microbiology 9(5), pp. 1146-1161. (10.1111/j.1462-2920.2006.01237.x)
- O'Sullivan, L. A.et al. 2007. Identifying the genetic basis of ecologically and biotechnologically useful functions of the bacterium Burkholderia vietnamiensis. Environmental Microbiology 9(4), pp. 1017-1034. (10.1111/j.1462-2920.2006.01228.x)
2006
- Fry, J. C.et al. 2006. Analysis of DGGE profiles to explore the relationship between prokaryotic community composition and biogeochemical processes in deep subseafloor sediments from the Peru Margin. FEMS Microbiology Ecology 58(1), pp. 86-98. (10.1111/j.1574-6941.2006.00144.x)
- Webster, G.et al. 2006. Prokaryotic community composition and biogeochemical processes in deep subseafloor sediments from the Peru Margin. FEMS Microbiology Ecology 58(1), pp. 65-85. (10.1111/j.1574-6941.2006.00147.x)
- Webster, G.et al. 2006. A comparison of stable-isotope probing of DNA and phospholipid fatty acids to study prokaryotic functional diversity in sulfate-reducing marine sediment enrichment slurries. Environmental Microbiology 8(9), pp. 1575-1589. (10.1111/j.1462-2920.2006.01048.x)
- Payne, G. W.et al. 2006. Application of a recA gene-based identification approach to the maize rhizosphere reveals novel diversity in Burkholderia species. FEMS Microbiology Letters 259(1), pp. 126-132. (10.1111/j.1574-6968.2006.00257.x)
- O'Sullivan, L. A.et al. 2006. Culturable phylogenetic diversity of the phylum 'Bacteroidetes' from river epilithon and coastal water and description of novel members of the family Flavobacteriaceae : Epilithonimonas tenax gen. nov., sp nov and Persicivirga xylanidelens gen. nov., sp nov.. International Journal of Systematic and Evolutionary Microbiology 56(1), pp. 169-180. (10.1099/ijs.0.63941-0)
- Ashelford, K. E.et al. 2006. New screening software shows that most recent large 16S rRNA gene clone libraries contain chimeras. Applied and Environmental Microbiology 72(9), pp. 5734-5741. (10.1128/AEM.00556-06)
- Kim, G. T.et al. 2006. Bacterial community structure, compartmentalization and activity in a microbial fuel cell. Journal of Applied Microbiology 101(3), pp. 698-710. (10.1111/j.1365-2672.2006.02923.x)
- Lillo, A.et al. 2006. Novel subgingival bacterial phylotypes detected using multiple universal polymerase chain reaction primer sets. Oral Microbiology and Immunology 21(1), pp. 61-68. (10.1111/j.1399-302X.2005.00255.x)
2005
- Ashelford, K. E.et al. 2005. At least 1 in 20 16S rRNA sequence records currently held in public repositories is estimated to contain substantial anomalies. Applied and Environmental Microbiology 71(12), pp. 7724-7736. (10.1128/AEM.71.12.7724-7736.2005)
- O'Sullivan, L. A.et al. 2005. Fluviicola taffensis gen. nov., sp nov., a novel freshwater bacterium of the family Cryomorphaceae in the phylum 'Bacteroidetes'. International Journal of Systematic and Evolutionary Microbiology 55(5), pp. 2189-2194. (10.1099/ijs.0.63736-0)
- Parkes, R. J.et al. 2005. Deep sub-seafloor prokaryotes stimulated at interfaces over geological time. Nature 436(7049), pp. 390-394. (10.1038/nature03796)
- Banning, N. C.et al. 2005. Investigation of the methanogen population structure and activity in a brackish lake sediment. Environmental Microbiology 7(7), pp. 947-960. (10.1111/j.1462-2920.2004.00766.x)
- Payne, G. W.et al. 2005. Development of a recA gene-based identification approach for the entire Burkholderia genus. Applied and Environmental Microbiology 71(7), pp. 3917-3927. (10.1128/AEM.71.7.3917-3927.2005)
- Kim, G. T.et al. 2005. Dissimilatory Fe(III) reduction by an electrochemically active lactic acid bacterium phylogenetically related to Enterococcus gallinarum isolated from submerged soil. Journal of Applied Microbiology 99(4), pp. 978-987. (10.1111/j.1365-2672.2004.02514.x)
- Wade, W. G.et al. 2005. Specificity of the oral microflora in dentinal caries, endodontic infections and periodontitis. International Congress Series 1284, pp. 150-157. (10.1016/j.ics.2005.06.097)
- Ahn, Y.et al. 2005. Biofilm microbial community of a thermophilic trickling biofilter used for continuous biohydrogen production. FEMS Microbiology Letters 249(1), pp. 31-38. (10.1016/j.femsle.2005.05.050)
2004
- Webster, G.et al. 2004. Widespread occurrence of a novel division of bacteria identified by 16S rRNA gene sequences originally found in deep marine sediments. Applied and Environmental Microbiology 70(9), pp. 5708-5713. (10.1128/AEM.70.9.5708-5713.2004)
- Newberry, C. J.et al. 2004. Diversity of prokaryotes and methanogenesis in deep subsurface sediments from the Nankai Trough, Ocean Drilling Program Leg 190. Environmental Microbiology 6(3), pp. 274-287. (10.1111/j.1462-2920.2004.00568.x)
- O'Sullivan, L. A.et al. 2004. Distribution and culturability of the uncultivated 'AGG58 cluster' of Bacteroidetes phylum in aquatic environments. FEMS Microbiology Ecology 47(3), pp. 359-370. (10.1016/S0168-6496(03)00300-3)
2003
- Hill, K. E. and Weightman, A. J. 2003. Horizontal transfer of dehalogenase genes on IncP1[beta] plasmids during bacterial adaptation to degrade [alpha]-halocarboxylic acids. FEMS Microbiology Ecology 45(3), pp. 273-282. (10.1016/S0168-6496(03)00158-2)
- Ellis, R. J.et al. 2003. Cultivation-dependent and -independent approaches for determining bacterial diversity in heavy-metal-contaminated soil. Applied and Environmental Microbiology 69(6), pp. 3223-3230. (10.1128/AEM.69.6.3223-3230.2003)
- Marchesi, J. R. and Weightman, A. J. 2003. Comparing the Dehalogenase Gene Pool in Cultivated -Halocarboxylic Acid-Degrading Bacteria with the Environmental Metagene Pool. Applied and Environmental Microbiology 69(8), pp. 4375-4382. (10.1128/AEM.69.8.4375-4382.2003)
- Marchesi, J. R. and Weightman, A. J. 2003. Diversity of alpha-halocarboxylic acid dehalogenases in bacteria isolated from a pristine soil after enrichment and selection on the herbicide 2,2-dichloropropionic acid (Dalapon). Environmental Microbiology 5(1), pp. 48-54. (10.1046/j.1462-2920.2003.00384.x)
2002
- Weightman, A. J.et al. 2002. Transposition of DEH, a broad-host-range transposon flanked by ISPpu12, in Pseudomonas putida is associated with genomic rearrangements and dehalogenase gene silencing. Journal of Bacteriology 184(23), pp. 6581-6591. (10.1128/JB.184.23.6581-6591.2002)
- O'Sullivan, L. A., Weightman, A. J. and Fry, J. C. 2002. New degenerate Cytophaga-Flexibacter-Bacteroides-specific 16S ribosomal DNA-targeted oligonucleotide probes reveal high bacterial diversity in River Taff epilithon. Applied and environmental microbiology 68(1), pp. 201-210. (10.1128/AEM.68.1.201-210.2002)
2001
- Marchesi, J. R.et al. 2001. Methanogen and bacterial diversity and distribution in deep gas hydrate sediments from the Cascadia Margin as revealed by 16S rRNA molecular analysis. FEMS Microbiology Ecology 34(3), pp. 221-228. (10.1111/j.1574-6941.2001.tb00773.x)
2000
- Poelarends, G. J.et al. 2000. Haloalkane-Utilizing Rhodococcus Strains Isolated from Geographically Distinct Locations Possess a Highly Conserved Gene Cluster Encoding Haloalkane Catabolism. Journal of Bacteriology 182(10), pp. 2725-2731. (10.1128/JB.182.10.2725-2731.2000)
1999
- Hill, K. E., Marchesi, J. R. and Weightman, A. J. 1999. Investigation of two evolutionarily unrelated halocarboxylic acid dehalogenase gene families. Journal of Bacteriology 181(9), pp. 2535-2547. (10.1128/JB.181.8.2535-2547.1999)
1997
- Ashelford, K. E.et al. 1997. Using microcosms to study gene transfer in aquatic habitats. FEMS Microbiology Ecology 23(2), pp. 81-94. (10.1111/j.1574-6941.1997.tb00393.x)
- Bale, S. J.et al. 1997. Desulfovibrio profundus sp. nov., a novel barophilic sulfate-reducing bacterium from deep sediment layers in the Japan Sea. International Journal of Systematic Bacteriology 47(2), pp. 515-521. (10.1099/00207713-47-2-515)
1995
- Hill, K. E.et al. 1995. Retrotransfer of IncP1-like plasmids from aquatic bacteria. Letters in Applied Microbiology 20(5), pp. 317-322. (10.1111/j.1472-765X.1995.tb00454.x)
- Cragg, B. A.et al. 1995. Bacterial Profiles in Deep Sediments of the Santa Barbara Basin, Site 893. Proceedings of the Ocean Drilling Program Scientific Results 146-2, pp. 139-144. (10.2973/odp.proc.sr.146-2.302.1995)
- Cragg, B. A.et al. 1995. The Impact of Fluid and Gas Venting on Bacterial Populations and Processes in Sediments from the Cascadia Margin Accretionary System (Sites 888-892) and the Geochemical Consequences. Proceedings of the Ocean Drilling Program Scientific Results 146-1, pp. 399-411. (10.2973/odp.proc.sr.146-1.241.1995)
1994
- Parkes, R. J.et al. 1994. Deep bacterial biosphere in Pacific Ocean sediments. Nature 371(6496), pp. 410-413. (10.1038/371410a0)
- Hill, K. E., Fry, J. C. and Weightman, A. J. 1994. Gene transfer in the aquatic environment: persistence and mobilization of the catabolic recombinant plasmid pD10 in the epilithon. Microbiology 140(7), pp. 1555-1563. (10.1099/13500872-140-7-1555)
- Rochelle, P. A.et al. 1994. Effect of sample handling on estimation of bacterial diversity in marine sediments by 16S rRNA gene sequence analysis. FEMS Microbiology Ecology 15(1-2), pp. 215-225. (10.1111/j.1574-6941.1994.tb00245.x)
1992
- Weightman, A. L., Weightman, A. J. and Slater, J. 1992. Microbial dehalogenation of trichloroacetic acid. World Journal of Micorobiology & Biotechnology 8(5), pp. 512-518. (10.1007/BF01201951)
- Hill, K. E., Weightman, A. J. and Fry, J. C. 1992. Isolation and screening of plasmids from the epilithon which mobilize recombinant plasmid pD10. Applied and Environmental Microbiology 58, pp. 1292-1300.
- Rochelle, P. A.et al. 1992. DNA extraction for 16S rRNA gene analysis to determine genetic diversity in deep sediment communities. FEMS Microbiology Letters 100(1-3), pp. 59-65. (10.1111/j.1574-6968.1992.tb14019.x)
1985
- Weightman, A. J., Weightman, A. L. and Slater, J. 1985. Toxic effects of chlorinated and brominated alkanoic acids on pseudomonas-putida PP3 : selction at high-frequencies of mutations in genes encoding dehalogenases. Applied and Environmental Microbiology 49(6), pp. 1494-1501.
1982
- Weightman, A. J., Weightman, A. L. and Slater, J. 1982. Stereospecificity of 2-monochloropropionate dehalogenation by the two dehalogenases of pseudomonas putida PP3: evidence for two different dehalogenation mechanisms. Journal of General Microbiology 128(8), pp. 1755-1762. (10.1099/00221287-128-8-1755)
Projects
- The Deep Sub-Seafloor Biosphere – adaptations to an extreme environment (EC, NERC)
- Aquatic microbial metagenomics and biogeochemical cycles (NERC)
- Adaptation of ecosystems to aliphatic organohalogens and the evolution of bacterial xenobiotic-degrading enzymes (NERC, AstraZeneca, Wellcome Trust)
- Tackling the problem of 16S rRNA chimeras through analysis of sequence regularity – a software solution (BBSRC)
- Development of a recA gene based identification approach for the entire Burkholderia genus (NERC)
- Studying prokaryotic diversity and interactions in deep terrestrial sediments (Leverhulme Trust)
- Microbial adaptation to degradation of natural and synthetic organohalogens: effects on ecosystem acclimation and natural bioremediation of polluted sites (EC)
- Do deep marine sediment layers contain uniquely adapted physiological types of anaerobic bacteria? (NERC)
- Microbial activity and diversity measurements as tools for improved evaluation of the environmental risks posed by contaminated soil and sediments (ICI/NERC)
Research group members
Affiliated staff
- Dr Gordon Webster
- Dr Amy Baldwin
- Dr Shrinivas Dighe
- Dr Jordan Cuff
- Vince Brookes
PhD students
- Holly Smith
- Hannah Salvage
- Franciszek Bydalek
