Dr Frank Hailer
Uwch-ddarlithydd
- hailerf@cardiff.ac.uk
- +44 (0)29 2087 4125
- Cardiff School of Biosciences, The Sir Martin Evans Building, Museum Avenue, Cardiff CF10 3AX, Adeilad Syr Martin Evans, Rhodfa'r Amgueddfa, Caerdydd, CF10 3AX
- Ar gael fel goruchwyliwr ôl-raddedig
Trosolwg
I am an evolutionary biologist working at the interface of genomics, molecular ecology and conservation biology.
I am part of the Cardiff University Otter Project, where we study otters in the UK and beyond. We are using a diversity of scientific approaches, for example studying their exposure to environmental contaminants, antimicrobial resistance and their population structuring.
Academic service
I serve as Reviews/Associate Editor for the journal Heredity (see here for submission guidelines: https://www.nature.com/hdy/authors-and-referees/gta) and asAssociate Editor for Animal Conservation. Please feel free to get in touch if you're interested in submitting to these journals.
During 2016-2020, I served on a time-limited post as Committee Member on the board of the Genetics Society UK, representing Population and Evolutionary Genetics.
Roles
- Module Leader BI3153 Evolution and Species Adaptation
- Organiser of Organisms and Environment departmental seminar series
- Safety co-ordinator for the Molecular Ecology labs
Interested in joining my research group?
I enjoy including students in my research. My research group offers various opportunities for undergraduate, Master's and PhD students, typically involving lab work and/or bioinformatics/statistical analysis. I am also happy to discuss with interested postdoc candidates about the potential to apply for funding from sources such as NERC, BBSRC, Marie-Sklodowska-Curie fellowships, etc.
If you are interested, please contact me by email.
Bywgraffiad
| Since 2015 | Lecturer, Cardiff University |
| 2011-2014 | Postdoc, Biodiversity and Climate Research Centre (BiK-F), Senckenberg Research Institute & Goethe University Frankfurt |
| 2007-2010 | Postdoc, Smithsonian National Zoo, Center for Conservation and Evolutionary Genetics, Smithsonian Institution, Washington, DC, USA |
| 2006-2007 | Postdoc, Department of Evolutionary Biology (EBC), Uppsala University, Sweden |
| 2006 | PhD, Evolutionary Genetics, Uppsala University, Sweden |
| 2001 | MSc, Biology, Uppsala University, Sweden |
| 1998 | Basic exam in Biology ('Vordiplom'), Marburg University, Germany |
After studies in biology at Marburg University (Germany), I completed my Master’s degree at Uppsala University (Sweden), where I continued to pursue PhD studies in the lab of Hans Ellegren and Carles Vilà (now at CSIC, Spain). My PhD work focused on conservation genetics of white-tailed eagles, but I also worked on other projects on dog domestication and canid population genetics. I then worked with Jennifer Leonard on hybridization of coyotes and wolves in North America. In 2007 I started a new postdoc with Rob Fleischer at the Smithsonian National Zoo. In 2010-2014 I worked at BiK-F in Axel Janke’s group, studying population genetics and adaptation of arctic vertebrates and their boreotemperate counterparts.
Aelodaethau proffesiynol
- Elected committee member of the Genetics Society UK (representing Area E: Evolutionary, ecological and population genetics)
- American Ornithological Society (AOS)
- European Soceity of Evolutionary Biology (ESEB)
Pwyllgorau ac adolygu
| Since 2018 | Reviews Editor for Heredity |
| Since 2012 | Associate Editor for Animal Conservation |
| 2014 - 2017 | Junior researcher representative on Goethe University Frankfurt's Graduate Academy (GRADE) |
| Peer reviewer for >40 journals [count updated in spring 2020] including PNAS, Molecular Biology and Evolution, Nature Ecology and Evolution, Molecular Ecology, Heredity, Nature Communications and Conservation Genetics |
Cyhoeddiadau
2023
- Basuony, A. et al. 2023. Paraphyly of the widespread generalist red fox (Vulpes vulpes): introgression rather than recent divergence of the arid-adapted Rüppell's fox (Vulpes rueppellii)?. Biological Journal of the Linnean Society (10.1093/biolinnean/blad001)
- Khan, S., Cable, J., Younus, M., Rashid, M. I., Hailer, F. and Akbar, H. 2023. IEg67 kDa bovine hydatid cyst antigen: a candidate for developing sero-diagnostic assays for cystic echinococcosis, a disease of one health importance. Animals 13(5), article number: 866. (10.3390/ani13050866)
2022
- Dearborn, D. C., Warren, S. and Hailer, F. 2022. Meta-analysis of major histocompatibility complex (MHC) class IIA reveals polymorphism and positive selection in many vertebrate species. Molecular Ecology 31(24), pp. 6390-6406. (10.1111/mec.16726)
- Thomas, N. E., Hailer, F., Bruford, M. W. and Chadwick, E. A. 2022. Country-wide genetic monitoring over 21 years reveals lag in genetic recovery despite spatial connectivity, in an expanding carnivore (Eurasian otter, Lutra lutra) population. Evolutionary Applications 15(12), pp. 2125-2141. (10.1111/eva.13505)
- Beard, A. et al. 2022. Increasing use of artificial nest chambers by seasonally segregated populations of band-rumped storm petrels hydrobates castro at St Helena, South Atlantic. Marine Ornithology
- O'Rourke, E. et al. 2022. Anthropogenic drivers of variation in concentrations of perfluoroalkyl substances in otters (Lutra lutra) from England and Wales. Environmental Science and Technology 56(3), pp. 1675-1687. (10.1021/acs.est.1c05410)
- Mullin, K. E., Firmin, D., White, N. F. D., Hailer, F. and Orozco ter Wengel, P. 2022. The complete mitochondrial genome of rare and critically endangered Anilany helenae (Microhylidae) of Madagascar. Mitochondrial DNA Part B: Resources 7(1), pp. 153-155. (10.1080/23802359.2021.2008841)
2021
- Mullin, K. E., Rakotomanga, M. G., Razafiarimanana, M. L., Barata, I. M., Dawson, J., Hailer, F. and Orozco ter Wengel, P. 2021. First amphibian inventory of one of Madagascar’s smallest protected areas, Ankafobe, extends the range of the Critically Endangered Anilany helenae (Vallan, 2000) and the Endangered Boophis andrangoloaka (Ahl, 1928). Herpetological Notes 14, pp. 521-531.
2020
- Watson, S. E. et al. 2020. Parasites of an Arctic scavenger; the wolverine (Gulo gulo). International Journal for Parasitology: Parasites and Wildlife 13, pp. 178-185. (10.1016/j.ijppaw.2020.10.004)
- Päckert, M. et al. 2020. “Into and out of” the Qinghai‐Tibet plateau and the Himalayas: centers of origin and diversification across five clades of Eurasian montane and alpine passerine birds. Ecology and Evolution 10(17), pp. 9283-9300. (10.1002/ece3.6615)
- Mead, D. et al. 2020. The genome sequence of the Eurasian river otter, Lutra lutra Linnaeus 1758 [version 1; peer review: 2 approved]. Wellcome Open Research 5, pp. 33. (10.12688/wellcomeopenres.15722.1)
- Barbato, M. et al. 2020. Adaptive introgression from indicine cattle into white cattle breeds from Central Italy. Scientific Reports, article number: 1279. (10.1038/s41598-020-57880-4)
2019
- Liu, Z. et al. 2019. Pseudogenization of Mc1r gene associated with transcriptional changes related to melanogensis explains leucistic phenotypes in Oreonectes cavefish (Cypriniformes, Nemacheilidae). Journal of Zoological Systematics and Evolutionary Research 57(4), pp. 900-909. (10.1111/jzs.12286)
- Hailer, F., Kutschera, V. E. and Zachos, F. E. 2019. A summary of brown bear genetic studies: Phylogeny, phylogeography and evolutionary relationships with polar bears. In: Schlup, P. and Hertwig, S. T. eds. Of Bears and Men: Conclusions of the 1st International Bear Meeting IBear. Bern: Haupt Verlag, pp. 10-29.
2017
- Barbato, M. et al. 2017. Genomic signatures of adaptive introgression from European mouflon into domestic sheep. Scientific Reports 7, article number: 7623. (10.1038/s41598-017-07382-7)
- Reiners, T. E., Fuchs, M., Hailer, F., Janke, A. and Nowak, C. 2017. Establishing species-specific sexing markers suitable for non-invasive samples of species lacking genomic resources: an example using the highly endangered common hamster Cricetus cricetus. Conservation Genetics Resources 9(2), pp. 253-255. (10.1007/s12686-016-0664-2)
2016
- Kutschera, V. E. et al. 2016. High genetic variability of vagrant polar bears illustrates importance of population connectivity in fragmented sea ice habitats. Animal Conservation 19(4), pp. 337-349. (10.1111/acv.12250)
- Liu, Z. et al. 2016. Dietary specialization drives multiple independent losses and gains in the bitter taste gene repertoire of Laurasiatherian Mammals. Frontiers in Zoology 13(1), article number: 28. (10.1186/s12983-016-0161-1)
- Rossi Lafferriere, N. A. et al. 2016. Multiple paternity in a reintroduced population of the Orinoco Crocodile (Crocodylus intermedius) at the El Frío Biological Station, Venezuela. PLOS ONE 11(3), article number: e0150245. (10.1371/journal.pone.0150245)
- Hailer, F. and Welch, A. J. 2016. Evolutionary history of polar and brown bears. In: eLS. Wiley-Blackwell, pp. 1-8., (10.1002/9780470015902.a0026303)
2015
- Schregel, J. et al. 2015. Y chromosome haplotype distribution of brown bears (Ursus arctos) in Northern Europe provides insight into population history and recovery. Molecular Ecology 24(24), pp. 6041-6060. (10.1111/mec.13448)
- Aarnes, S. G. et al. 2015. Y-chromosomal testing of brown bears (Ursus arctos): Validation of a multiplex PCR-approach for nine STRs suitable for fecal and hair samples. Forensic Science International: Genetics 19, pp. 197. (10.1016/j.fsigen.2015.07.018)
- Bidon, T., Schreck, N., Hailer, F., Nilsson, M. A. and Janke, A. 2015. Genome-wide search identifies 1.9 Mb from the polar bear Y chromosome for evolutionary analyses. Genome Biology and Evolution 7(7), pp. 2010-2022. (10.1093/gbe/evv103)
- Hailer, F. 2015. Introgressive hybridization: brown bears as vectors for polar bear alleles. Molecular Ecology 24(6), pp. 1161-1163. (10.1111/mec.13101)
- Hailer, F., James, H. . F., Olson, S. L. and Fleischer, R. C. 2015. Distinct and extinct: Genetic differentiation of the Hawaiian eagle. Molecular Phylogenetics and Evolution 83, pp. 40-43. (10.1016/j.ympev.2014.11.005)
2014
- Bock, F., Gallus, S., Janke, A., Hailer, F., Steck, B. L., Kumar, V. and Nilsson, M. A. 2014. Genomic resources and genetic diversity of captive lesser kudu (Tragelaphus imberbis). Zoo Biology 33(5), pp. 440-445. (10.1002/zoo.21146)
- Kutschera, V. E., Bidon, T., Hailer, F., Rodi, J. L., Fain, S. R. and Janke, A. 2014. Bears in a forest of gene trees: Phylogenetic inference is complicated by incomplete lineage sorting and gene flow. Molecular Biology and Evolution 31(8), pp. 2004-2017. (10.1093/molbev/msu186)
- Bidon, T. et al. 2014. Brown and polar bear Y chromosomes reveal extensive male-biased gene flow within brother lineages. Molecular Biology and Evolution 31(6), pp. 1353-1363. (10.1093/molbev/msu109)
- Sanchez-Donoso, I., Huisman, J., Echegaray, J., Puigcerver, M., Rodriguez-Teijeiro, J. D., Hailer, F. and Vila, C. 2014. Detecting slow introgression of invasive alleles in an extensively restocked game bird. Frontiers in Ecology and Evolution 2014(2) (10.3389/fevo.2014.00015)
2013
- Gonzalez-Porter, G. P., Maldonado, J. E., Flores-Villela, O., Vogt, R. C., Janke, A., Fleischer, R. C. and Hailer, F. 2013. Cryptic population structuring and the role of the Isthmus of Tehuantepec as a gene flow barrier in the critically endangered Central American River Turtle. Plos One 8(9), article number: e71668. (10.1371/journal.pone.0071668)
- Kawai, K., Hailer, F., Pauline de Guia, A., Ichikawa, H. and Saitoh, T. 2013. Refugia in Glacial Ages Led to the Current Discontinuous Distribution Patterns of the Dark Red-backed Vole Myodes rex on Hokkaido, Japan. Zoological Science 30(8), pp. 642-650. (10.2108/zsj.30.642)
- Kutschera, V. E. et al. 2013. A range-wide synthesis and timeline for phylogeographic events in the red fox (Vulpes vulpes). BMC Evolutionary Biology 13, article number: 114. (10.1186/1471-2148-13-114)
- Langguth, T., Honnen, A., Hailer, F., Mizera, T., Skoric, S., Vali, U. and Zachos, F. E. 2013. Genetic structure and phylogeography of a European flagship species, the white-tailed sea eagle Haliaeetus albicilla. Journal of Avian Biology 44(3), pp. 263-271.
- Kuhn, T., Hailer, F., Palm, H. W. and Klimpel, S. 2013. Global assessment of molecularly identified Anisakis Dujardin, 1845 (Nematoda: Anisakidae) in their teleost intermediate hosts. Folia Parasitologica 60(2), pp. 123-134. (10.14411/fp.2013.013)
- Bidon, T. et al. 2013. A sensitive and specific multiplex PCR approach for sex identification of ursine and tremarctine bears suitable for non-invasive samples. Molecular Ecology Resources 13(3), pp. 362-368. (10.1111/1755-0998.12072)
- Hailer, F., Kutschera, V. E., Hallstroem, B. M., Fain, S. R., Leonard, J. A., Arnason, U. and Janke, A. 2013. Response to comment on "Nuclear genomic sequences reveal that Polar Bears are an old and distinct bear lineage". Science 339(6127), pp. 1522. (10.1126/science.1228066)
2012
- Kleven, O., Hallstroem, B. M., Hailer, F., Janke, A., Hagen, S. B., Kopatz, A. and Eiken, H. G. 2012. Identification and evaluation of novel di- and tetranucleotide microsatellite markers from the brown bear (Ursus arctos). Conservation Genetics Resources 4(3), pp. 737-741. (10.1007/s12686-012-9634-5)
- Hailer, F. et al. 2012. Nuclear genomic sequences reveal that polar bears are an old and distinct bear lineage. Science 336(6079), pp. 344-347. (10.1126/science.1216424)
2011
- Gonzalez-Porter, G. P., Hailer, F., Flores-Villela, O., Garcia-Anleu, R. and Maldonado, J. E. 2011. Patterns of genetic diversity in the critically endangered Central American river turtle: human influence since the Mayan age?. Conservation Genetics 12(5), pp. 1229-1242. (10.1007/s10592-011-0225-x)
- Bozarth, C. A., Hailer, F., Rockwood, L. L., Edwards, C. W. and Maldonado, J. E. 2011. Coyote colonization of northern Virginia and admixture with Great Lakes wolves. Journal of Mammalogy 92(5), pp. 1070-1080. (10.1644/10-MAMM-A-223.1)
- Ahlering, M. A., Hailer, F., Roberts, M. T. and Foley, C. 2011. A simple and accurate method to sex savannah, forest and asian elephants using noninvasive sampling techniques. Molecular Ecology Notes 11(5), pp. 831-834. (10.1111/j.1755-0998.2011.03030.x)
- Levin, I. I. et al. 2011. Hippoboscid-transmitted Haemoproteus parasites (Haemosporida) infect Galapagos Pelecaniform birds: Evidence from molecular and morphological studies, with a description of Haemoproteus iwa. International Journal for Parasitology 41(10), pp. 1019-1027. (10.1016/j.ijpara.2011.03.014)
- Hailer, F., Schreiber, E. A., Miller, J. M., Levin, I. I., Parker, P. G., Chesser, R. T. and Fleischer, R. C. 2011. Long-term isolation of a highly mobile seabird on the Galapagos. Proceedings of the Royal Society B: Biological Sciences 278(1707), pp. 817-825. (10.1098/rspb.2010.1342)
2010
- Andree, K. et al. 2010. Permanent genetic resources added to Molecular Ecology Resources Database 1 April 2010-31 May 2010. Molecular Ecology Resources 10(6), pp. 1098-1105. (10.1111/j.1755-0998.2010.02898.x)
- Honnen, A., Hailer, F., Kenntner, N., Literak, I., Dubska, L. and Zachos, F. E. 2010. Mitochondrial DNA and nuclear microsatellites reveal high diversity and genetic structure in an avian top predator, the white-tailed sea eagle, in central Europe. Biological Journal of the Linnean Society Linnean Society of London 99(4), pp. 727-737. (10.1111/j.1095-8312.2010.01373.x)
2009
- Dowling, D. K., Maklakov, A. A., Friberg, U. and Hailer, F. 2009. Applying the genetic theories of ageing to the cytoplasm: cytoplasmic genetic covariation for fitness and lifespan. Journal of Evolutionary Biology 22(4), pp. 818-827. (10.1111/j.1420-9101.2009.01692.x)
- Johnson, J. A., Tingay, R. E., Culver, M., Hailer, F., Clarke, M. L. and Mindell, D. P. 2009. Long-term survival despite low genetic diversity in the critically endangered Madagascar fish-eagle. Molecular Ecology 18(1), pp. 54-63. (10.1111/j.1365-294X.2008.04012.x)
2008
- Dearborn, D. C., Hailer, F. and Fleischer, R. C. 2008. Microsatellite primers for relatedness and population structure in great frigatebirds (Pelecaniformes: Fregatidae). Molecular Ecology Resources 8(6), pp. 1399-1401. (10.1111/j.1755-0998.2008.02351.x)
- Hailer, F. and Leonard, J. A. 2008. Hybridization among three native North American Canis species in a region of natural sympatry. Plos One 3(10), article number: e3333. (10.1371/journal.pone.0003333)
- Bjornerfeldt, S., Hailer, F., Nord, M. and Vila, C. 2008. Assortative mating and fragmentation within dog breeds. BMC Evolutionary Biology 8, article number: 28. (10.1186/1471-2148-8-28)
2007
- Helander, B., Hailer, F. and Vilà, C. 2007. Morphological and genetic sex identification of white-tailed eagle Haliaeetus albicilla nestlings. Journal of Ornithology 148(4), pp. 435-442. (10.1007/s10336-007-0156-y)
- Hailer, F. et al. 2007. Phylogeography of the white-tailed eagle, a generalist with large dispersal capacity. Journal of Biogeography 34(7), pp. 1193-1206. (10.1111/j.1365-2699.2007.01697.x)
- Tingay, R. E., Dawson, D. A., Pandhal, J., Clarke, M. L., David, V. A., Hailer, F. and Culver, M. 2007. Isolation of 22 new Haliaeetus microsatellite loci and their characterization in the critically endangered Madagascar fish-eagle (Haliaeetus vociferoides) and three other Haliaeetus eagle species. Molecular Ecology Notes 7(4), pp. 711-715. (10.1111/j.1471-8286.2007.01690.x)
- Dowling, D. K., Friberg, U., Hailer, F. and Arnqvist, G. 2007. Intergenomic epistasis for fitness: within-population interactions between cytoplasmic and nuclear genes in Drosophila melanogaster. Genetics 175(1), pp. 235-244. (10.1534/genetics.105.052050)
2006
- Hailer, F. et al. 2006. Bottlenecked but long-lived: high genetic diversity retained in white-tailed eagles upon recovery from population decline. Biology Letters 2(2), pp. 316-319. (10.1098/rsbl.2006.0453)
- Sundqvist, A. K., Björnerfeldt, S., Leonard, J. A., Hailer, F., Hedhammar, A., Ellegren, H. and Vilà, C. 2006. Unequal contribution of sexes in the origin of dog breeds. Genetics 172(2), pp. 1121-1128. (10.1534/genetics.105.042358)
2005
- Hailer, F., Gautschi, B. and Helander, B. 2005. Development and multiplex PCR amplification of novel microsatellite markers in the White-tailed Sea Eagle, Haliaeetus albicilla (Aves : Falconiformes, Accipitridae). Molecular Ecology Notes 5(4), pp. 938-940. (10.1111/j.1471-8286.2005.01122.x)
Addysgu
Undergraduate level:
- BI1003 Introduction to Conservation Biology
- BI2131 Animal Diversity and Adaptation
- BI2132 Genetics and its Applications
- BI2134 Ecology and Conservation (part B: field course 'Marine Conservation' on Borneo)
- BI3153 Evolution and Adaptation (module leader)
- BI3154 Biodiversity and Conservation
Master's level:
- BIT002 Research Techniques in Biosciences
Genetics and Genomics
My research interests are broad, focussing on surveying genetic variation within and among species to infer key processes in ecology and evolution, such as speciation, adaptation, introgression and population structuring. I am also interested in the causes and consequences of dispersal, mechanisms of loss or maintenance of genetic diversity, and disease ecology.
Understanding these processes often requires knowledge about population structure and phylogeographic history. Hence, my research traces the origin and fate of genetic variation within individuals to their populations and species, and continues deeper into phylogenetic time scales. In this context I find it particularly fascinating to see how independently inherited parts of the genome reflect different aspects of present and past processes.
In my research I have studied a wide range of taxa, including bears, eagles, various species of tropical seabirds, wolves, coyotes and dogs, turtles, fruit flies, lynxes, elephants etc., spanning arctic to tropical habitats.
Ecology and Conservation
In my group we also use a variety of field-based or other (non-genetic) approaches to study biodiversity, for example:
- Work on various aspects of seabird biology and our affiliation with the Cardiff University Storm Petrel team (see us on Twitter), as well as
- A variety of mammal studies and links to the Cardiff University Otter Group (Twitter)
