Ewch i’r prif gynnwys
Yr Athro Alun Davies FRS

Yr Athro Alun Davies

FRS

Professor

Ysgol y Biowyddorau

Email:
daviesalun@cardiff.ac.uk
Telephone:
+44 (0)29 2087 4303
Location:
Cardiff School of Biosciences, The Sir Martin Evans Building, Museum Avenue, Cardiff, CF10 3AX, Adeilad Syr Martin Evans, Rhodfa'r Amgueddfa, Caerdydd, CF10 3AX

Research overview

We use a wide variety of cellular, molecular and transgenic approaches to understand the regulation of neuronal survival and the growth of neural processes in the developing vertebrate nervous system, focusing on the functions and mechanisms of action of neurotrophic factors and members of the TNF superfamily. We mostly work on experimentally advantageous populations of neurons in the peripheral nervous system, but have begun to apply our multi-disciplinary approach to study dendritic development in the central nervous system.

Research division

Molecular Biosciences

Vacancies

We frequently have vacancies for post-doctoral fellows to carry out research in the field of developmental neurobiology, trophic factor biology and signalling.  Please contact Alun Davies daviesalun@cardiff.ac.uk for details.

I did degrees in biochemistry and medicine at Liverpool University followed by a PhD in developmental neurobiology at London University. I have held appointments as Lecturer, Senior Lecturer and Reader in Neurobiology in London University, Professor of Developmental Neurobiology at St. Andrews University School of Biology, Professor of Physiology at Edinburgh University Veterinary School and Executive Vice President of Research at Rinat Neuroscience Corp., USA.

I was elected Fellow of the Royal Society of Edinburgh in 2000, Member of the European Molecular Biology Organisation in 2000, Fellow of the Academy of Medical Sciences in 2010, Fellow of the Learned Society of Wales in 2011, Member of the Academia Europaea in 2011 and Fellow of the Royal Society in 2011. I was appointed Distinguished Research Professor in Cardiff University in 2004 and became a Wellcome Trust Senior Investigator in 2014.

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We use a variety of approaches to investigate how secreted signalling molecules affect the generation and survival of neurons and influence the establishment and modification of their connections in the developing vertebrate nervous system. We have established well-characterised cell culture systems to ascertain the roles of these factors at defined stages in neuroblast and neuronal development and we transgenic technology to investigate the consequences of mutations in the genes encoding these factors, their receptors and other regulatory molecules. We have a particular current interest in the role of the tumor necrosis factor superfamily in regulating the growth of neural processes.

Research team members

Post-doctoral researchers

PhD students

Research grants

Wellcome Trust Senior Investigator Award, 2014-2019, £2,043,743 'TNF superfamily forward and reverse signalling in neural development'

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