Dr Sian Morgan
Research Associate (Structural Biophysics Group)
- Ar gael fel goruchwyliwr ôl-raddedig
Trosolwg
My research focus is related to the optical and biomechanical properties of transparent materials. I am using techniques such as cell and organ culture, synchrotron x-ray studies, electron microscopy and histology to investigate how the various hierarchical structures within these materials give rise to their transparency and refractive status.
Bywgraffiad
EDUCATIONAL AND PROFESSIONAL QUALIFICATIONS
2010 – 2014: PhD, Understanding the structural basis of corneal refractive function and its modification via novel therapeutic approaches, Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University.
2009 – 2010: PGCE Secondary Science (11-16), Swansea School of Education, Swansea Metropolitan University (Swansea School of Education).
2008 – 2009: Distinction MSc Biomedical Sciences Research, Faculty of Medical and Veterinary Sciences, University of Bristol (Faculty of Medical and Veterinary Sciences).
2003 – 2006: 2:1 BSc (Hons) Biochemistry with Molecular Biology, School of Biosciences, Cardiff University.
PROFESSIONAL EXPERIENCE
2016 – Present: Cardiff University Research Staff Association (CURSA) Representative
2011 – Present: Science, Technology, Engineering and Mathematics (STEM) Ambassador
2012 – 2013: Chair of Cardiff Institute of Tissue Engineering and Repair (CITER) Soc
PUBLICATIONS
Morgan, S.R. et al. 2016. Early wound healing of LASIK-like flaps following treatment with human corneal stromal stem cells. Journal of Cataract & Refractive Surgery. 42(2), pp. 302-309. (10.1016/j.jcrs.2015.09.023)
Hayes, S. et al. 2015. A study of stromal riboflavin absorption in ex vivo porcine corneas using new and existing delivery protocols for corneal cross-linking. Acta Ophthalmologica. 94(2), pp. 109-117. (10.1111/aos.12884)
Morgan, S.R. et al. 2013. An x-ray scattering study into the structural basis of corneal refractive function in an avian model. Biophysical Journal. 104(12), pp. 2586-2594. (10.1016/j.bpj.2013.04.053).
Boote, C.et al. 2012. Quantitative assessment of ultrastructure and light scatter in mouse corneal debridement wounds. Investigative Ophthalmology and Visual Science 53(6), pp. 2786-2795. (10.1167/iovs.11-9305)
Anrhydeddau a Dyfarniadau
1st prize for poster presentation at the British Society for Matrix Biology Spring 2011 meeting, Bristol.
2nd prize for poster presentation at the Speaking of Science conference, Cardiff University, 2011.
1st prize for poster presentation at the Bristol Vision Institute: Young Vision Researchers' Colloquium, Cardiff University, 2013.
CITER conference bursary- CITER, Cardiff University, 2013.
Funding for Interdisciplinary Activities - CITER Soc proposal accepted by the University Graduate College, Cardiff University, 2013.
Safleoedd academaidd blaenorol
Oct 2016 – Present: Research Associate, Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University.
Jan 2016 – Sept 2016: Research Associate, Novel modulators of the visual cycle for treatment of retinal degenerations, School of Optometry and Vision Sciences, Cardiff University.
2014 – 2015: Research Associate, Investigating the biological induction of maturation and its potential to provide stable tissue engineered cartilage for aesthetic and reconstructive facial surgery, The Welsh Centre for Burns and Plastic Surgery, ABMU/ReconRegen, and Centre for NanoHealth, Swansea University.
2013 – 2014: Website Administrator, UK Cross-linking Consortium, Cardiff University.
Pwyllgorau ac adolygu
2016 – Present: Cardiff Institute of Tissue Engineering and Repair (CITER) Engagement Committee Member
Cyhoeddiadau
2022
- Rumney, B. M. et al. 2022. Characterisation of carapace composition in developing and adult ostracods (Skogsbergia lerneri) and its potential for biomaterials. Marine Biology 169(6), article number: 78. (10.1007/s00227-022-04047-6)
- Rumney, B. M. et al. 2022. The ultrastructural development and 3D reconstruction of the transparent carapace of the ostracod Skogsbergia lerneri. Marine Biology 169, article number: 35. (10.1007/s00227-021-04006-7)
2021
- Hayes, S., Morgan, S. R. and Meek, K. M. 2021. Keratoconus: cross-linking the window of the eye. Therapeutic Advances in Rare Disease 2, pp. 1-14. (10.1177/26330040211003573)
2020
- Pasqualetto, G. et al. 2020. Computational studies towards the identification of novel rhodopsin-binding compounds as chemical chaperones for misfolded opsins. Molecules 25(21), article number: 4904. (10.3390/molecules25214904)
- Morgan, S. R. et al. 2020. Establishment of long-term ostracod epidermal culture. In Vitro Cellular and Developmental Biology - Animal 56(9), pp. 760-772. (10.1007/s11626-020-00508-8)
- Morgan, S. R. et al. 2020. Controlled in vitro delivery of voriconazole and diclofenac to the cornea using contact lenses for the treatment of Acanthamoeba keratitis. International Journal of Pharmaceutics 579, article number: 119102. (10.1016/j.ijpharm.2020.119102)
- Hewitt, M. G. et al. 2020. In Vitro Topical Delivery of Chlorhexidine to the Cornea: Enhancement Using Drug-Loaded Contact Lenses and β-Cyclodextrin Complexation, and the Importance of Simulating Tear Irrigation. Molecular Pharmaceutics 17(4), pp. 1428-1441. (10.1021/acs.molpharmaceut.0c00140)
2018
- Morgan, S. et al. 2018. Microwave treatment of the cornea leads to localised disruption of the extracellular matrix. Scientific Reports 8, article number: 13742. (10.1038/s41598-018-32110-0)
2016
- Morgan, S., Dooley, E. P., Kamma-Lorger, C., Funderburgh, J. L., Funderburgh, M. and Meek, K. 2016. Early wound healing of laser in situ keratomileusis?like flaps after treatment with human corneal stromal stem cells. Journal of Cataract & Refractive Surgery 42(2), pp. 302-309. (10.1016/j.jcrs.2015.09.023)
- Jessop, Z. M. et al. 2016. Combining regenerative medicine strategies to provide durable reconstructive options: auricular cartilage tissue engineering. Stem Cell Research and Therapy 7, article number: 19. (10.1186/s13287-015-0273-0)
2015
- Hayes, S., Morgan, S. R., O'Brart, D. P., O'Brart, N. and Meek, K. M. A. 2015. A study of stromal riboflavin absorption inex vivoporcine corneas using new and existing delivery protocols for corneal cross-linking. Acta Ophthalmologica 94(2), pp. e109-e117. (10.1111/aos.12884)
2013
- Morgan, S. R. et al. 2013. An X-Ray scattering study into the structural basis of corneal refractive function in an Avian Model. Biophysical Journal 104(12), pp. 2586-2594. (10.1016/j.bpj.2013.04.053)
2012
- Boote, C. et al. 2012. Quantitative assessment of ultrastructure and light scatter in mouse corneal debridement wounds. Investigative Ophthalmology and Visual Science 53(6), pp. 2786-2795. (10.1167/iovs.11-9305)
Addysgu
Supervision of Masters, Erasmus and Final Year project students
