Dr Lucy Riglin
Research Associate, Division of Psychological Medicine and Clinical Neurosciences
- riglinl@cardiff.ac.uk
- +44 (0)29 2068 8419
- Desk 2.01 - 57, Adeilad Hadyn Ellis, Heol Maendy, Caerdydd, CF24 4HQ
Trosolwg
I am investigating the impact of genetic risk scores for mental disorders on specific neurodevelopmental domains measured in childhood, including emotional regulation, cognition, social communication and behavioural regulation.
Cyhoeddiadau
2023
- Thapar, A., Livingston, L. A., Eyre, O. and Riglin, L. 2023. Practitioner Review: Attention‐deficit hyperactivity disorder and autism spectrum disorder – the importance of depression. Journal of Child Psychology and Psychiatry 64(1), pp. 4-15. (10.1111/jcpp.13678)
2022
- Riglin, L. and Stergiakouli, E. 2022. Mendelian randomisation studies of Attention Deficit Hyperactivity Disorder. JCPP Advances 2(4), article number: e12117. (10.1002/jcv2.12117)
- Sellers, R., Riglin, L., Harold, G. and Thapar, A. 2022. Using genetic designs to identify likely causal environmental contributions to psychopathology. Development and Psychopathology 34(5), pp. 1653-1665. (10.1017/S0954579422000906)
- Pat, N., Yue, W., Anney, R., Riglin, L., Thapar, A. and Argyris, S. 2022. Longitudinally stable, brain-based predictive models mediate the relationships between childhood cognition and socio-demographic, psychological and genetic factors.. Human Brain Mapping 43(18), pp. 5520-5542. (10.1002/hbm.26027)
- Riglin, L. et al. 2022. Early manifestations of genetic liability for ADHD, autism and schizophrenia at ages 18 and 24 months. JCPP Advances 2(3), article number: e12093. (10.1002/jcv2.12093)
- Tobarra‐Sanchez, E., Riglin, L., Agha, S. S., Stergiakouli, E., Thapar, A. and Langley, K. 2022. Preschool development, temperament and genetic liability as early markers of childhood ADHD: A cohort study. JCPP Advances 2(3), article number: e12099. (10.1002/jcv2.12099)
- Havdahl, A. et al. 2022. Associations between pregnancy-related predisposing factors for offspring neurodevelopmental conditions and parental genetic liability to Attention-Deficit/Hyperactivity Disorder, Autism, and Schizophrenia: The Norwegian Mother, Father and Child Cohort Study (MoBa). JAMA Psychiatry 79(8), pp. 799-810. (10.1001/jamapsychiatry.2022.1728)
- Riglin, L. et al. 2022. “Late-onset” ADHD symptoms in young adulthood: is this the same as child-onset ADHD?. Journal of Attention Disorders 26(10), pp. 1271-1282. (10.1177/10870547211066486)
- Wootton, R. E. et al. 2022. Decline in attention-deficit hyperactivity disorder traits over the life course in the general population: trajectories across five population birth cohorts spanning ages 3 to 45 years. International Journal of Epidemiology 51(3), pp. 919-930. (10.1093/ije/dyac049)
- Thapar, A., Livingston, L., Eyre, O. and Riglin, L. 2022. Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder: The Importance of Depression. Journal of Child Psychology and Psychiatry
- Pat, N., Riglin, L., Anney, R., Wang, Y., Barch, D., Thapar, A. and Stringaris, A. 2022. Motivation and cognitive abilities as mediators between polygenic scores and psychopathology in children. Journal of the American Academy of Child and Adolescent Psychiatry 61(6), pp. 782-795., article number: e3. (10.1016/j.jaac.2021.08.019)
- Niina, A., Eyre, O., Wooton, R., Stergiakouli, E., Thapar, A. and Riglin, L. 2022. Exploring ADHD symptoms and associated impairment across development. Journal of Attention Disorders 26(6), pp. 822-830. (10.1177/10870547211025612)
- Riglin, L. et al. 2022. Assessment of age-at-onset criterion for adult attention-deficit hyperactivity disorder. British Journal of Psychiatry 220(2), pp. 73-75. (10.1192/bjp.2021.122)
- Wimberley, T. et al. 2022. Early-life injuries and the development of attention-deficit/hyperactivity disorder. Journal of Clinical Psychiatry 83(1) (10.4088/JCP.21m14033)
- Riglin, L. et al. 2022. Investigating young-adult social outcomes of attention deficit hyperactivity disorder. Journal of Clinical Psychiatry
2021
- Dardani, C. et al. 2021. Is genetic liability to ADHD and ASD causally linked to educational attainment?. International Journal of Epidemiology 50(6), pp. 2011-2023. (10.1093/ije/dyab107)
- Eyre, O. et al. 2021. Validation of the short Mood and Feelings Questionnaire in young adulthood. Journal of Affective Disorders 294, pp. 883-888. (10.1016/j.jad.2021.07.090)
- Martin, J. et al. 2021. Sex differences in anxiety and depression in children with ADHD investigating genetic liability and comorbidity. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 186(7), pp. 412-422. (10.1002/ajmg.b.32842)
- Riglin, L. et al. 2021. ADHD and depression: investigating a causal explanation. Psychological Medicine 51(11), pp. 1890-1897. (10.1017/S0033291720000665)
- Riglin, L. et al. 2021. Variable emergence of Autism Spectrum Disorder symptoms from childhood to early adulthood. American Journal of Psychiatry 178(8), pp. 752-760. (10.1176/appi.ajp.2020.20071119)
- Powell, V. et al. 2021. Investigating friendship difficulties in the pathway from ADHD to depressive symptoms. Can parent-child relationships compensate?. Research on Child and Adolescent Psychopathology 49, pp. 1031-1041. (10.1007/s10802-021-00798-w)
- Riglin, L. et al. 2021. Investigating the validity of the strengths and difficulties questionnaire to assess ADHD in young adulthood. Psychiatry Research 301, article number: 113984. (10.1016/j.psychres.2021.113984)
- Leppert, B. et al. 2021. The effect of ADHD on physical health outcomes - a two-sample Mendelian randomization study. American Journal of Epidemiology 190(6), pp. 1047-1055. (10.1093/aje/kwaa273)
- Rice, F. et al. 2021. Pupil mental health, concerns and expectations about secondary school as predictors of adjustment across the transition to secondary school: A longitudinal multi-informant study. School Mental Health 13, pp. 279-298. (10.1007/s12310-021-09415-z)
- Riglin, L. et al. 2021. Investigating attention‐deficit hyperactivity disorder and autism spectrum disorder traits in the general population: What happens in adult life?. Journal of Child Psychology and Psychiatry 62(4), pp. 449-457. (10.1111/jcpp.13297)
2020
- Powell, V. et al. 2020. What explains the link between childhood ADHD and adolescent depression? Investigating the role of peer relationships and academic attainment. European Child and Adolescent Psychiatry 29, pp. 1581-1591. (10.1007/s00787-019-01463-w)
- Thapar, A. and Riglin, L. 2020. The importance of a developmental perspective in Psychiatry: what do recent genetic epidemiological findings show?. Molecular Psychiatry 25, pp. 1631-1639. (10.1038/s41380-020-0648-1)
- Riglin, L. et al. 2020. Using genetics to examine a general liability to childhood psychopathology. Behavior Genetics 50, pp. 213-220. (10.1007/s10519-019-09985-4)
- Wimberle, T. et al. 2020. Genetic liability to ADHD and substance use disorders in individuals with ADHD. Addiction 115(7), pp. 1368-1377. (10.1111/add.14910)
- Leppart, B. et al. 2020. A cross-disorder PRS-pheWAS of 5 major psychiatric disorders in UK Biobank. PLoS Genetics 16(5), article number: e1008185. (10.1371/journal.pgen.1008185)
- Addicoat, A., Thapar, A., Riglin, L., Thapar, A. and Collishaw, S. 2020. Adult mood problems in children with neurodevelopmental problems: evidence from a prospective birth cohort followed to age 50. Social Psychiatry and Psychiatric Epidemiology 55, pp. 351-358. (10.1007/s00127-019-01727-5)
2019
- Ng-Knight, T., Shelton, K. H., Riglin, L., Frederickson, N., McManus, I. C. and Rice, F. 2019. 'Best friends forever'? Friendship stability across school transition and associations with mental health and educational attainment. British Journal of Educational Psychology 89(4), pp. 585-599. (10.1111/bjep.12246)
- Eyre, O., Riglin, L., Stringaris, A., Collishaw, S. and Thapar, A. 2019. Irritability in ADHD: association with later depression symptoms. European Child and Adolescent Psychiatry 28(10), pp. 1375-1384. (10.1007/s00787-019-01303-x)
- Riglin, L. et al. 2019. Identifying novel types of irritability using a developmental genetic approach. American Journal of Psychiatry 176(8), pp. 635-642. (10.1176/appi.ajp.2019.18101134)
- Leppert, B. et al. 2019. Association of maternal neurodevelopmental risk alleles with early-life exposures. JAMA Psychiatry 76(8), pp. 834-842. (10.1001/jamapsychiatry.2019.0774)
- Kendall, K. M. et al. 2019. Association of rare copy number variants with risk of depression. JAMA Psychiatry 76(8), pp. 818-825. (10.1001/jamapsychiatry.2019.0566)
- Rice, F., Riglin, L., Thapar, A. K., Heron, J., Anney, R., O'Donovan, M. C. and Thapar, A. 2019. Characterizing developmental trajectories and the role of neuropsychiatric genetic risk variants in early-onset depression. JAMA Psychiatry 76(3), pp. 306-313. (10.1001/jamapsychiatry.2018.3338)
- Richards, A. et al. 2019. Associations between schizophrenia genetic risk, anxiety disorders and manic/hypomanic episode in a New Zealand longitudinal population cohort study. British Journal of Psychiatry 214(2), pp. 96-102. (10.1192/bjp.2018.227)
- Rice, F. et al. 2019. Adolescent and adult differences in major depression symptom profiles. Journal of Affective Disorders 243, pp. 175-181. (10.1016/j.jad.2018.09.015)
- Riglin, L. et al. 2019. Developmental contributions of schizophrenia risk alleles and childhood peer victimization to early-onset mental health trajectories. American Journal of Psychiatry 176(1), pp. 36-43. (10.1176/appi.ajp.2018.18010075)
2018
- Riglin, L. et al. 2018. The impact of schizophrenia and mood disorder risk alleles on emotional problems: investigating change from childhood to middle age. Psychological Medicine 48(13), pp. 2153-2158. (10.1017/S0033291717003634)
- Cooper, M. et al. 2018. Investigating late-onset ADHD: a population cohort investigation. Journal of Child Psychology and Psychiatry 59(10), pp. 1105-1113. (10.1111/jcpp.12911)
- Martin, J. et al. 2018. Sex-specific manifestation of genetic risk for attention deficit hyperactivity disorder in the general population. Journal of Child Psychology and Psychiatry 59(8), pp. 908-916. (10.1111/jcpp.12874)
- White, E. K. et al. 2018. Twin classroom dilemma: To study together or separately?. Developmental Psychology 54(7), pp. 1244-1254. (10.1037/dev0000519)
2017
- Riglin, L. et al. 2017. Investigating the genetic underpinnings of early-life irritability. Translational Psychiatry 7, article number: e1241. (10.1038/tp.2017.212)
- Riglin, L., Collishaw, S., Richards, A., Thapar, A., Maughan, B., O'Donovan, M. C. and Thapar, A. 2017. Schizophrenia polygenic risk score and psychotic risk detection - authors' reply. The Lancet Psychiatry 4(3), pp. 188-189. (10.1016/S2215-0366(17)30052-4)
- Rice, F., Eyre, O., Riglin, L. and Potter, R. 2017. Adolescent depression and the treatment gap. The Lancet Psychiatry 4(2), pp. 86-87. (10.1016/S2215-0366(17)30004-4)
- Riglin, L., Collishaw, S., Richards, A., Thapar, A. K., Maughan, B., O'Donovan, M. C. and Thapar, A. 2017. Schizophrenia risk alleles and neurodevelopmental outcomes in childhood: a population-based cohort study. Lancet Psychiatry 4(1), pp. 57-62. (10.1016/S2215-0366(16)30406-0)
2016
- Riglin, L. et al. 2016. Association of genetic risk variants with attention-deficit/hyperactivity disorder trajectories in the general population. JAMA Psychiatry 73(12), pp. 1285-1292. (10.1001/jamapsychiatry.2016.2817)
- Ng-Knight, T., Shelton, K. H., Riglin, L., McManus, I., Frederickson, N. and Rice, F. 2016. A longitudinal study of self-control at the transition to secondary school: Considering the role of pubertal status and parenting. Journal of Adolescence 50, pp. 44-55. (10.1016/j.adolescence.2016.04.006)
- Neal, S., Rice, F., Ng-Knight, T., Riglin, L. and Frederickson, N. 2016. Exploring the longitudinal association between interventions to support the transition to secondary school and child anxiety. Journal of Adolescence 50, pp. 31-43. (10.1016/j.adolescence.2016.04.003)
- Riglin, L., Thapar, A., Shelton, K. H., Langley, K., Frederickson, N. and Rice, F. 2016. Profiling depression in childhood and adolescence: the role of conduct problems. Journal of Child Psychology and Psychiatry 57(4), pp. 481-490. (10.1111/jcpp.12465)
- Riglin, L. et al. 2016. Higher cognitive ability buffers stress-related depressive symptoms in adolescent girls. Development and Psychopathology 28(1), pp. 97-109. (10.1017/S0954579415000310)
2015
- McManus, I. C., Ng-Knight, T., Riglin, L., Frederickson, N., Shelton, K. H. and Rice, F. 2015. Doctor, builder, soldier, lawyer, teacher, dancer, shopkeeper, vet: exploratory study of which eleven-year olds would like to become a doctor. BMC Psychology 3(1), article number: 38. (10.1186/s40359-015-0094-z)
- Rice, F., Rawal, A., Riglin, L., Lewis, G., Lewis, G. and Dunsmuir, S. 2015. Examining reward-seeking, negative self-beliefs and over-general autobiographical memory as mechanisms of change in classroom prevention programs for adolescent depression. Journal of Affective Disorders 186, pp. 320-327. (10.1016/j.jad.2015.07.019)
2014
- Rawal, A., Riglin, L., Ng-Knight, T., Collishaw, S., Thapar, A. and Rice, F. 2014. A longitudinal high-risk study of adolescent anxiety, depression and parent-severity on the developmental course of risk-adjustment. Journal of Child Psychology and Psychiatry 55(11), pp. 1270-1278. (10.1111/jcpp.12279)
- Riglin, L., Petrides, K., Frederickson, N. and Rice, F. 2014. The relationship between emotional problems and subsequent school attainment: A meta-analysis. Journal of Adolescence 37(4), pp. 335-346. (10.1016/j.adolescence.2014.02.010)
2013
- Riglin, L., Frederickson, N., Shelton, K. H. and Rice, F. 2013. A longitudinal study of psychological functioning and academic attainment at the transition to secondary school. Journal of Adolescence 36(3), pp. 507-517. (10.1016/j.adolescence.2013.03.002)
