Dr Arfon Powell

Wcat Fellow

Yr Ysgol Meddygaeth

: powella16@cardiff.ac.uk
: UHW Main Building

: Siarad Cymraeg
: Ar gael fel goruchwyliwr ôl-raddedig

I am a Wales Clinical Academic Track (WCAT) trainee in general surgery with a subspeciality interest in oesophagogastric cancer.

I undertook my pre-doctoral research training with Dr Joanne Edwards and Professors Paul Horgan and Donald McMillan at the University of Glasgow. Research studies looking at the relationship between cancer-related inflammation and genomic instablity culminated in the award of a PhD.

My current research looks at genomic and epigentic changes observed in patients with cancer-related inflammation and its influence on response to treatment and survival in patients with oesophagogastric cancer.

Education and qualifications

Doctor of Philosophy (PhD) in Cancer Science, University of Glasgow, 2016
Master of Science (MSc) in Surgical Science (Distinction), University of Edinburgh, 2011
Membership of the Royal College of Surgeons (MRCS), Edinburgh, 2009
Bachelor of Medicine and Bachelor of Surgery (MB ChB), University of Aberdeen, 2007

Anrhydeddau a Dyfarniadau

Enid linder Award, University of Aberdeen - 2006
Shepherd Memorial Medal in Surgery, University of Aberdeen - 2007
Dukes Club/ACPGBI Prize, ASiT National Conference - 2011

Aelodaethau proffesiynol

American Association of Cancer Research
Association of Upper GI Surgeons
British Association of Cancer Research
The Royal College of Surgeons of Edinburgh

2020

Roseweir, A. K.et al. 2020. Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer. The Journal of Pathology: Clinical Research 6(4), pp. 283-296. (10.1002/cjp2.171)
Robinson, D. B. T.et al. 2020. Surgical training rotation design: effects of hospital type, rotation theme and duration. BJS Open 4(5), pp. 970-976. (10.1002/bjs5.50326)
Robinson, D. B. T.et al. 2020. Egalitarianism in surgical training: let equity prevail. Postgraduate Medical Journal 96(1141), pp. 650-654. (10.1136/postgradmedj-2020-137563)
Powell, A. G. M. T.et al. 2020. Physiological performance and inflammatory markers as indicators of complications after oesophageal cancer surgery. BJS Open 4(5), pp. 840-846. (10.1002/bjs5.50328)
Powell, A. G. M. T.et al. 2020. Prognostic significance of serum inflammatory markers in esophageal cancer. Esophagus (10.1007/s10388-020-00772-3)
Powell, A.et al. 2020. Propensity score regression analysis of oesophageal cancer treatment with surgery alone or neoadjuvant chemotherapy. BJS Open 4(4), pp. 593-600. (10.1002/bjs5.50287)
Koushyar, S.et al. 2020. Targeting Wnt signaling for the treatment of gastric cancer. International Journal of Molecular Sciences 21(11), article number: 3927. (10.3390/ijms21113927)
Powell, A. G. M. T.et al. 2020. Neutrophil-lymphocyte ratio as a predictor of response to neoadjuvant chemotherapy and survival in oesophageal adenocarcinoma. BJS Open 4(3), pp. 416-423. (10.1002/bjs5.50277)
Powell, A. G. M. T.et al. 2020. Team strategic philosophy: requiem for the infinite game. Postgraduate Medical Journal 96(1136), pp. 310-312. (10.1136/postgradmedj-2019-137441)
Powell, A. G. M. T.et al. 2020. Value of individual surgeon performance metrics as quality assurance measures in oesophagogastric cancer surgery. BJS Open 4(1), pp. 91-100. (10.1002/bjs5.50230)
Hopkins, L.et al. 2020. Summative supervisor reporting: a quality performance perspective. Journal of Surgical Education 77(1), pp. 88-95. (10.1016/j.jsurg.2019.08.021)
Powell, A. G. M. T.et al. 2020. Prognostic significance of compound physiology variables in oesophageal cancer. BJS Open

2019

Drake, T. M.et al. 2019. Outcomes following small bowel obstruction due to malignancy in the national audit of small bowel obstruction. EJSO - European Journal of Surgical Oncology 45(12), pp. 2319-2324. (10.1016/j.ejso.2019.07.014)
Brown, C.et al. 2019. Prospective cohort study of haptic virtual reality laparoscopic appendicectomy learning curve trajectory. Journal of Laparoendoscopic and Advanced Surgical Techniques 29(9), pp. 1128-1134. (10.1089/lap.2019.0332)
Patel, N.et al. 2019. Cardiopulmonary fitness predicts postoperative major morbidity after esophagectomy for patients with cancer. Physiological Reports 7(14), pp. -., article number: e14174. (10.14814/phy2.14174)
Karsan, R. B.et al. 2019. The top 100 manuscripts in emergency cardiac surgery. Potential role in cardiothoracic training. A bibliometric analysis. Annals of Medicine and Surgery 43, pp. 5-12. (10.1016/j.amsu.2019.05.002)
Patel, N.et al. 2019. Propensity score analysis of 18-FDG PET/CT-enhanced staging in patients undergoing surgery for esophageal cancer. European Journal of Nuclear Medicine and Molecular Imaging 46(4), pp. 801-809. (10.1007/s00259-018-4118-9)
Robinson, D. B. T.et al. 2019. Relative value of adapted novel bibliometrics in evaluating surgical academic impact and reach. World Journal of Surgery 43(4), pp. 967-972. (10.1007/s00268-018-04893-w)
Williams, A.et al. 2019. Mode of presentation rather than the 'weekend effect' is a major determinant of in-hospital mortality. Surgeon 17(1), pp. 15-18. (10.1016/j.surge.2018.04.007)
Roseweir, A.et al. 2019. A novel tumor-based epithelial-to-mesenchymal transition score that associates with prognosis and metastasis in patients with stage II/III colorectal cancer. International Journal of Cancer 144(18), pp. 150-159. (10.1002/ijc.31739)
Roseweir, A. K.et al. 2019. Src family kinases, HCK and FGR, associate with local inflammation and tumour progression in colorectal cancer. Cellular Signalling 56, pp. 15-22. (10.1016/j.cellsig.2019.01.007)

2018

Barlow, R. C.et al. 2018. Fit for Cancer Treatment: a prospective feasibility study of primary care initiated prehabilitation for patients with suspected cancer. BJGP Open 2(4), article number: 18X101608. (10.3399/bjgpopen18X101608)
Powell, A.et al. 2018. Prognostic significance of post-operative morbidity severity score after potentially curative D2 gastrectomy for carcinoma. Journal of Gastrointestinal Surgery 22(9), pp. 1516-1527. (10.1007/s11605-018-3787-9)
Powell, A. G.et al. 2018. Altmetric versus bibliometric perspective regarding publication impact and force. World Journal of Surgery 42(9), pp. 2745-2756. (10.1007/s00268-018-4579-9)
Mellor, K. L., Powell, A. G. M. T. and Lewis, W. G. 2018. Systematic review and meta-analysis of the prognostic significance of Neutrophil-Lymphocyte Ratio (NLR) After R0 gastrectomy for cancer. Journal of Gastrointestinal Cancer 49(3), pp. 237-244. (10.1007/s12029-018-0127-y)
Roseweir, A. K.et al. 2018. ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer. British Journal of Cancer 119, pp. 323-329. (10.1038/s41416-018-0174-y)
Powell, A.et al. 2018. Prognostic significance of serum inflammatory markers in gastric cancer. Journal of Gastrointestinal Surgery 22(4), pp. 595-605. (10.1007/s11605-017-3597-5)
Powell, A.et al. 2018. Meta-analysis of the prognostic value of CpG island methylator phenotype in gastric cancer. British Journal of Surgery 105(2), pp. e61-e68. (10.1002/bjs.10742)

2017

Powell, A.et al. 2017. Esophageal cancer's 100 most influential manuscripts: a bibliometric analysis. Diseases of the Esophagus 30(4), pp. 1-8. (10.1093/dote/dow039)
Powell, A.et al. 2017. Mo1226 - Prognostic significance of serum inflammatory markers in gastric cancer. Gastroenterology 152(5 (S1)), pp. S1256. (10.1016/S0016-5085(17)34227-0)
Ellul, T.et al. 2017. The 100 most cited manuscripts in emergency abdominal surgery: a bibliometrics analysis. International Journal of Surgery 37, pp. 29-35. (10.1016/j.ijsu.2016.12.006)

2016

Dreyer, S. B.et al. 2016. The pre treatment systemic inflammatory response is an important determinant of poor pathologic response for patients undergoing neoadjuvant therapy for rectal cancer. Annals of Surgical Oncology (10.1245/s10434-016-5684-3)
Matthews, A.et al. 2016. Surgical education's 100 most cited articles: A bibliometric analysis. Journal of Surgical Education 73(5), pp. 919-929. (10.1016/j.jsurg.2016.05.011)
Roseweir, A. K.et al. 2016. Relationship between tumour PTEN/Akt/COX-2 expression, inflammatory response and survival in patients with colorectal cancer. Oncotarget 7(43), pp. 70601-70612. (10.18632/oncotarget.12134)
Foley, K.et al. 2016. The 100 most cited articles investigating the radiological staging of oesophageal and junctional cancer: a bibliometric analysis. Insights into Imaging 7(4), pp. 619-628. (10.1007/s13244-016-0505-6)
Mansouri, D.et al. 2016. Long-term follow-up of patients undergoing resection of TNM Stage I colorectal cancer: An analysis of tumour and host determinants of outcome. World Journal of Surgery 40(6), pp. 1485-1491. (10.1007/s00268-016-3443-z)
Powell, A.et al. 2016. The 100 most influential manuscripts in gastric cancer: a bibliometric analysis. International Journal of Surgery 28, pp. 83-90. (10.1016/j.ijsu.2016.02.028)
Park, J. H.et al. 2016. Mismatch repair status in patients with primary operable colorectal cancer: associations with the local and systemic tumour environment. British Journal of Cancer 114(5), pp. 562-570. (10.1038/bjc.2016.17)
Powell, A., Hughes, D. and Hill, S. 2016. The relationship between pre-operative anaemia, clinicopathological factors and survival in patients undergoing surgery for soft tissue sarcoma. British Journal of Surgery 103, pp. 19-19.

2015

Powell, A.et al. 2015. Prognostic significance of T (LNR) M in staging gastric cancer incorporating pathological lymph node ratio (LNR). Gastroenterology 148(4), pp. S550-S551. (10.1016/S0016-5085(15)31846-1)
Wheat, J.et al. 2015. Prognostic significance of T (LNR) M in staging esophageal cancer incorporating pathological lymph node ratio (LNR). Gastroenterology 148(4), pp. S551. (10.1016/S0016-5085(15)31849-7)
Park, J. H.et al. 2015. Evaluation of a tumor microenvironment-based prognostic score in primary operable colorectal cancer. Clinical Cancer Research 21(4), pp. 882-888. (10.1158/1078-0432.CCR-14-1686)

2014

Park, J. H.et al. 2014. Mismatch repair status, host local and systemic inflammatory responses and survival in patients with primary operable colorectal cancer. Gastroenterology 146(5), pp. S1035-S1036., article number: Su1785. (10.1016/S0016-5085(14)63773-2)
Powell, A., Paterson-Brown, S. and Drummond, G. B. 2014. Undergraduate medical textbooks do not provide adequate information on intravenous fluid therapy: a systematic survey and suggestions for improvement. BMC Medical Education 14(1), pp. 35. (10.1186/1472-6920-14-35)
Richards, C. H.et al. 2014. The clinical utility of the local inflammatory response in colorectal cancer. European Journal of Cancer 50(2), pp. 309-319. (10.1016/j.ejca.2013.09.008)

2013

Roxburgh, C. S.et al. 2013. The in situ local immune response, tumour senescence and proliferation in colorectal cancer. British Journal of Cancer 109(8), pp. 2207-2216. (10.1038/bjc.2013.556)

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