
Dr Meike Heurich-Sevcenco
Research Associate
Ysgol Fferylliaeth a Gwyddorau Fferyllol
- heurichm@cardiff.ac.uk
- Adeilad Redwood , Rhodfa'r Brenin Edward VII, Caerdydd, CF10 3NB
- Ar gael fel goruchwyliwr ôl-raddedig
Cyhoeddiadau
2022
- Heurich, M., Föcking, M., Mongan, D., Cagney, G. and Cotter, D. R. 2022. Dysregulation of complement and coagulation pathways: emerging mechanisms in the development of psychosis. Molecular Psychiatry 27, pp. 127-140. (10.1038/s41380-021-01197-9)
2021
- Baker, A. T. et al. 2021. ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome. Science Advances 7(49), article number: eabl8213. (10.1126/sciadv.abl8213)
- Pathare, N., Szakmany, T., Hall, J. E. and Heurich, M. 2021. Plasma IgM levels differentiate between survivors and non-survivors of culture-positive and culture-negative sepsis and SIRS: a pilot study. Journal of Clinical Medicine 10(22), article number: 5391. (10.3390/jcm10225391)
- Howes, O., Cummings, C. and Heurich, M. 2021. Translation from genes to mechanism in schizophrenia: are immune-synaptic interactions the missing link?. Biological Psychiatry 90(9), pp. 593-595. (10.1016/j.biopsych.2021.08.014)
- Flude, B. M. et al. 2021. Targeting the complement serine protease MASP-2 as a therapeutic strategy for coronavirus infections. Viruses 13(2), article number: 312. (10.3390/v13020312)
- Mongan, D. et al. 2021. Development of proteomic prediction models for transition to psychotic disorder in the clinical high-risk state and psychotic experiences in adolescence. JAMA Psychiatry 78(1), pp. 77-90. (10.1001/jamapsychiatry.2020.2459)
2019
- Madrid-Gambin, F. et al. 2019. Integrated lipidomics and proteomics point to early blood-based changes in childhood preceding later development of psychotic experiences: evidence from the Avon Longitudinal Study of Parents and Children. Biological Psychiatry 86(1), pp. 25-34. (10.1016/j.biopsych.2019.01.018)
- Föcking, M. et al. 2019. Complement pathway changes at age 12 are associated with psychotic experiences at age 18 in a longitudinal population-based study: evidence for a role of stress. Molecular Psychiatry 26, pp. 524-533. (10.1038/s41380-018-0306-z)
2016
- Heurich-Sevcenco, M., Preston, R., O'Donnell, V. B., Morgan, B. P. and Collins, P. W. 2016. Thrombomodulin enhances complement regulation through strong affinity interactions with factor H and C3b-Factor H complex. Thrombosis Research 145, pp. 84-92. (10.1016/j.thromres.2016.07.017)
2015
- Martínez-Barricarte, R. et al. 2015. The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome. Molecular Immunology 66(2), pp. 263-273. (10.1016/j.molimm.2015.03.248)
- Szakmany, T. and Heurich-Sevcenco, M. 2015. Immunomodulation in sepsis - why blunting the response doesn't work?. Journal of Infection 71(2), pp. 147-149. (10.1016/j.jinf.2015.04.019)
2014
- Ruseva, M. and Heurich-Sevcenco, M. 2014. Purification and characterization of human and mouse complement C3. In: Gadjeva, M. ed. The Complement System: Methods and Protocols., Vol. 1100. Methods in Molecular Biology Humana Press, pp. 75-91., (10.1007/978-1-62703-724-2_6)
2013
- Heurich, M., Altintas, Z. and Tothill, I. 2013. Computational Design of Peptide Ligands for Ochratoxin A. Toxins 5(6), pp. 1202-1218. (10.3390/toxins5061202)
2012
- Harris, C. L., Heurich, M., Rodriguez de Cordoba, S. and Morgan, B. P. 2012. The complotype: dictating risk for inflammation and infection. Trends in Immunology 33(10), pp. 513-521. (10.1016/j.it.2012.06.001)
2011
- Heurich, M., Martinez-Barricarte, R., Francis, N., Roberts, D. L., Rodriguez de Cordoba, S., Morgan, B. P. and Harris, C. L. 2011. Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk. Proceedings of the National Academy of Sciences of the United States of America 108(21), pp. 8761-8766. (10.1073/pnas.1019338108)
2010
- Martínez-Barricarte, R. et al. 2010. Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation. Journal of Clinical Investigation 120(10), pp. 3702-3712. (10.1172/JCI43343)