Yr Athro Maurice Hallett

2020

• Al-Jumaa, M., Hallett, M. B. and Dewitt, S. 2020. Cell surface topography controls phagocytosis and cell spreading: the membrane reservoir in neutrophils. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 12, article number: 118832. (10.1016/j.bbamcr.2020.118832)
• Dewitt, S. and Hallett, M. B. 2020. Calpain activation by Ca2+ and its role in phagocytosis. In: Hallett, M. B. ed. Molecular and Cellular Biology of Phagocytosis., Vol. 1246. Advances in Experimental Medicine and Biology Switzerland: Springer, pp. 129-151., (10.1007/978-3-030-40406-2_8)
• Roberts, R. E., Dewitt, S. and Hallett, M. B. 2020. Membrane tension and the role of ezrin during phagocytosis. In: Hallett, M. B. ed. Molecular and Cellular Biology of Phagocytosis., Vol. 1246. Advances in Experimental Medicine and Biology Switzerland: Springer, pp. 83-102., (10.1007/978-3-030-40406-2_6)
• Roberts, R. E.et al. 2020. Ca2+-activated cleavage of ezrin visualised dynamically in living myeloid cells during cell surface area expansion. Journal of Cell Science 133(5), article number: jcs236968. (10.1242/jcs.236968)

2019

• Hallett, M. B., Roberts, R. E. and Dewitt, S. 2019. Optical methods for the measurement and manipulation of cytosolic calcium signals in neutrophils. In: Neutrophil., Vol. 2087. Methods in Molecular Biology New York: Humana Press, pp. 191-205., (10.1007/978-1-0716-0154-9_14)
• Hallett, M. B.et al. 2019. Microinjection and micropipette-controlled phagocytosis methods for neutrophils. In: Neutrophil., Vol. 2087. Methods in Molecular Biology New York: Humana Press, pp. 117-125., (10.1007/978-1-0716-0154-9_9)
• Jennings, S. and Hallett, M. B. 2019. Single cell measurement of calpain activity in neutrophils reveals link to cytosolic Ca2+ elevation and individual phagocytotic events. Biochemical and Biophysical Research Communications 515(1), pp. 163-168. (10.1016/j.bbrc.2019.05.125)
• Roberts, R. and Hallett, M. 2019. Neutrophil cell shape change: mechanism and signalling during cell spreading and phagocytosis. International Journal of Molecular Sciences 20(6), article number: 1383. (10.3390/ijms20061383)

2018

• Ishak, R. and Hallett, M. B. 2018. Defective rapid cell shape and transendothelial migration by calpain-1 null neutrophils. Biochemical and Biophysical Research Communications 506(4), pp. 1065-1070. (10.1016/j.bbrc.2018.10.174)
• Roberts, R. E., Elumalai, G. L. and Hallett, M. B. 2018. Phagocytosis and motility in human neutrophils is competent but compromised by pharmacological inhibition of ezrin phosphorylation. Current Molecular Pharmacology 11(4), pp. 305-315. (10.2174/1874467211666180516100613)
• Hallett, M. 2018. The neutrophil: cellular biochemistry and physiology. CRC Press/Taylor & Francis. (10.1201/9781351077200)

2017

• Jumaa, M. A. A., Dewitt, S. and Hallett, M. B. 2017. Topographical interrogation of the living cell surface reveals its role in rapid cell shape changes during phagocytosis and spreading. Scientific Reports 7, pp. -., article number: 9790. (10.1038/s41598-017-09761-6)

2015

• Adams, S.et al. 2015. Conformationally restricted calpain inhibitors. Chemical Science 6(12), pp. 6865-6871. (10.1039/c5sc01158b)
• Campbell, J. S. and Hallett, M. 2015. Active calpain in phagocytically competent human neutrophils: electroinjection of fluorogenic calpain substrate. Biochemical and Biophysical Research Communications 457(3), pp. 341-346. (10.1016/j.bbrc.2014.12.113)

2014

• Adams, S. E.et al. 2014. The structural basis of differential inhibition of human calpain by indole and phenyl α--mercaptoacrylic acids. Journal of Structural Biology 187(3), pp. 236-241. (10.1016/j.jsb.2014.07.004)
• Lewis, K. J.et al. 2014. Minimal impact electro-injection of cells undergoing dynamic shape change reveals calpain activation. BBA - Molecular Cell Research 1843(6), pp. 1182-1187. (10.1016/j.bbamcr.2014.02.020)
• Hallett, M., Al-Jumaa, M. and Dewitt, S. 2014. Optical methods for the measurement and manipulation of cytosolic calcium signals in neutrophils. In: Quinn, M. T. and DeLeo, F. R. eds. Neutrophil Methods and Protocols. Methods in Molecular Biology Vol. 1124. Humana Press, pp. 107-120., (10.1007/978-1-62703-845-4_8)
• Laffafian, I.et al. 2014. Microinjection methods for neutrophils. In: Quinn, M. T. and DeLeo, F. R. eds. Neutrophil Methods and Protocols. Methods in Molecular Biology Vol. 1124. Humana Press, pp. 181-187., (10.1007/978-1-62703-845-4_11)

2013

• Miller, D. J.et al. 2013. Calpain-1 inhibitors for selective treatment of rheumatoid arthritis: what is the future?. Future Medicinal Chemistry 5(17), pp. 2057-2074. (10.4155/fmc.13.172)
• Dewitt, S., Francis, R. J. and Hallett, M. B. 2013. Ca2+ and calpain control membrane expansion during rapid cell spreading of neutrophils. Journal of Cell Science 126(20), pp. 4627-4635. (10.1242/jcs.124917)
• Midgley, A. C.et al. 2013. Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation Is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts. Journal of Biological Chemistry 288(21), pp. 14824-14838. (10.1074/jbc.M113.451336)
• Francis, R. J., Kotecha, S. and Hallett, M. B. 2013. Ca2+ activation of cytosolic calpain induces the transition from apoptosis to necrosis in neutrophils with externalized phosphatidylserine. Journal of Leukocyte Biology 93(1), pp. 95-100. (10.1189/jlb.0412212)

2012

• Adams, S. E.et al. 2012. Potent inhibition of Ca2+-dependent activation of calpain-1 by novel mercaptoacrylates. MedChemComm 3(5), pp. 566-570. (10.1039/c2md00280a)

2011

• Brasen, J. C., Olsen, L. F. and Hallett, M. B. 2011. Extracellular ATP induces spikes in cytosolic free Ca2+ but not in NADPH oxidase activity in neutrophils. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1813(8), pp. 1446-1452. (10.1016/j.bbamcr.2011.05.002)
• McDonald, J. U.et al. 2011. In vivo functional analysis and genetic modification of in vitro-derived mouse neutrophils. The FASEB Journal 25(6), pp. 1972-1982. (10.1096/fj.10-178517)
• Dewitt, S. and Hallett, M. B. 2011. Optical complexities of living cytoplasm - implications for live cell imaging and photo-micromanipulation techniques. Journal of Microscopy 241(3), pp. 221-224. (10.1111/j.1365-2818.2010.03451.x)
• Elumalai, G. L., Dewitt, S. and Hallett, M. B. 2011. Ezrin and talin relocates from the plasma membrane to cytosol during neutrophil extravasation [Abstract]. European Journal of Clinical Investigation 41(s1), pp. 47. (10.1111/j.1365-2362.2011.02508.x)
• Lewis, K., Dewitt, S. and Hallett, M. B. 2011. The role of calpain translocation in neutrophil spreading [Abstract]. European Journal of Clinical Investigation 41(s1), pp. 47. (10.1111/j.1365-2362.2011.02508.x)
• Francis, R. J., Kotecha, S. and Hallett, M. B. 2011. Ca2+ events in apoptosis and necrosis of neutrophils [Abstract]. European Journal of Clinical Investigation 41(s1), pp. 46-47. (10.1111/j.1365-2362.2011.02508.x)
• Ishak, R., Dewitt, S. and Hallett, M. B. 2011. Calpain-1: investigating its role in murine neutrophils [Abstract]. European Journal of Clinical Investigation 41(s1), pp. 24. (10.1111/j.1365-2362.2011.02508.x)
• Hallett, M. B. and Dewitt, S. 2011. A trick of the light: the optical properties of living cytoplasm which can mislead. Integrative Biology 3(3), pp. 180-184. (10.1039/c0ib00039f)

2010

• Brasen, J. C., Dewitt, S. and Hallett, M. B. 2010. A reporter of UV intensity delivered to the cytosol during photolytic uncaging. Biophysical Journal 98(7), pp. L25-L27. (10.1016/j.bpj.2009.12.4271)
• Brasen, J. C., Olsen, L. F. and Hallett, M. B. 2010. Cell surface topology creates high Ca2+ signalling microdomains. Cell Calcium 47(4), pp. 339-349. (10.1016/j.ceca.2010.01.005)

2009

• Yang, J.et al. 2009. Low connexin channel-dependent intercellular communication in human adult hematopoietic progenitor/stem cells: Probing mechanisms of autologous stem cell therapy. Cell Communication and Adhesion 16(5-6), pp. 138-145. (10.3109/15419061003653763)
• Dewitt, S., Darley, R. L. and Hallett, M. B. 2009. Translocation or just location? Pseudopodia affect fluorescent signals. Journal of Cell Biology 184(2), pp. 197-203. (10.1083/jcb.200806047)
• Hallett, M. B.et al. 2009. Fantastic Ca2+ "z-waves" fade out quietly. Cell Calcium 46(1), pp. 85-86. (10.1016/j.ceca.2009.04.003)
• Verma, V.et al. 2009. Perturbing plasma membrane hemichannels attenuates calcium signalling in cardiac cells and HeLa cells expressing connexins. European Journal of Cell Biology 88(2), pp. 79-90. (10.1016/j.ejcb.2008.08.005)

2008

• Hallett, M. . B., Von Ruhland, C. J. and Dewitt, S. 2008. Chemotaxis and the cell surface-area problem [Letter]. Nature Reviews Molecular Cell Biology 9(8), pp. 662. (10.1038/nrm2419-c1)
• Saltmarsh, E. J. and Hallett, M. B. 2008. Addressing controversy in localised Ca2+ signals in human neutrophils [Abstract]. European Journal of Clinical Investigation 38(S1), pp. 62. (10.1111/j.1365-2362.2008.01926.x)
• Hallett, M. B. and Williams, A. S. 2008. Stopping the traffic: A route to arthritis therapy. European Journal of Immunology 38(10), pp. 2650-2653. (10.1002/eji.200838786)
• Taneja, R.et al. 2008. Immature circulating neutrophils in sepsis have impaired phagocytosis and calcium signaling. Shock 30(6), pp. 618-622. (10.1097/SHK.0b013e318173ef9c)
• Lennon, S. V.et al. 2008. Elevations in cytosolic free Ca2+ are not required to trigger apoptosis in human leukaemia cells. Clinical and Experimental Immunology 87(3), pp. 465-471. (10.1111/j.1365-2249.1992.tb03021.x)

2007

• Dewitt, S. and Hallett, M. B. 2007. Leukocyte membrane 'expansion': a central mechanism for leukocyte extravasation. Journal of leukocyte biology 81(5), pp. 1160-1164. (10.1189/jlb.1106710)
• Hillson, E. J., Dewitt, S. and Hallett, M. B. 2007. Optical methods for the measurement and manipulation of cytosolic free calcium in neutrophils. In: Quinn, M. T., DeLeo, F. R. and Bokoch, G. M. eds. Neutrophil Methods and Protocols. Methods in Molecular Biology Vol. 412. Totowa, NJ: Humana Press, pp. 125-137., (10.1007/978-1-59745-467-4_10)

2006

• Hallett, M. B., Dewitt, S. and Tian, W. 2006. Localised PtdIns(3,4,5)P3 or PtdIns(3,4)P2 at the phagocytic cup is required for both phagosome closure and Ca2+ signalling in HL60 neutrophils. Journal of Cell Science 119(3), pp. 443-51. (10.1242/jcs.02756)

2004

• Ayub, K.et al. 2004. Ca2+ influx shutdown in neutrophils induced by Fas (CD95) cross-linking. Immunology 112(3), pp. 454-460. (10.1111/j.1365-2567.2004.01899.x)
• Clayton, A.et al. 2004. Adhesion and signaling by B cell-derived exosomes: the role of integrins. The FASEB Journal 18, pp. 977-979. (10.1096/fj.03-1094fje)

2003

• Tian, W.et al. 2003. Exclusion of exogenous phosphatidylinositol-3,4,5-trisphosphate from neutrophil-polarizing pseudopodia: stabilization of the uropod and cell polarity. EMBO Reports 4(10), pp. 982-988. (10.1038/sj.embor.embor947)
• Hallett, M. B., Laffafian, I. and Dewitt, S. 2003. Phagosomal oxidative activity during beta2 integrin (CR3)-mediated phagocytosis by neutrophils is triggered by a non-restricted Ca2+ signal: Ca2+ controls time not space. Journal of Cell Science 116(14), pp. 2857-65. (10.1242/jcs.00499)
• Dewitt, S.et al. 2003. Cytosolic Ca2+ measurement and imaging in inflammatory cells. In: Winyard, P. G. and Willoughby, D. A. eds. Inflammation Protocols. Methods in Molecular Biology Vol. 255. Totowa, NJ: Humana Press, pp. 47-63., (10.1385/1-59259-374-7:47)
• Hallett, M. B., Cole, C. and Dewitt, S. 2003. Detection and visualization of oxidase activity in phagocytes. In: Winyard, P. G. and Willoughby, D. A. eds. Inflammation Protocols., Vol. 225. Methods in Molecular Biology Totowa, NJ: Humana Press, pp. 61-67., (10.1385/1-59259-374-7:61)
• Morris, M. R.et al. 2003. Phagocytosis by inflammatory phagocytes; experimental strategies for stimulation and quantification. In: Winyard, P. G. and Willoughby, D. A. eds. Inflammation Protocols. Methods in Molecular Biology Vol. 225. Totowa, NJ: Humana Press, pp. 35-46., (10.1385/1-59259-374-7:35)

2002

• Hallett, M. B. and Dewitt, S. 2002. Cytosolic free Ca(2+) changes and calpain activation are required for beta integrin-accelerated phagocytosis by human neutrophils. The Journal of Cell Biology 159(1), pp. 181-9. (10.1083/jcb.200206089)
• Brown, S. A.et al. 2002. Factor VIIa induced release of von Willebrand factor from human umbilical vein endothelial cells by a tyrosine kinase dependent pathway. Journal of Thrombosis and Haemostasis 87, pp. 1057-1061.
• Hiscox, S. E.et al. 2002. GPI-anchored GFP signals Ca2+ but is homogeneously distributed on the cell surface. Biochemical and Biophysical Research Communications 293(2), pp. 714-721. (10.1016/S0006-291X(02)00280-2)

2001

• Sathish, J. G.et al. 2001. Requirement for CD28 co-stimulation is lower in SHP-1-deficient T cells. European Journal of Immunology 31(12), pp. 3649-3658. (10.1002/1521-4141(200112)31:12<3649::AID-IMMU3649>3.0.CO;2-8)

1998

• Pettit, E. J. and Hallett, M. B. 1998. Release of 'caged' cytosolic Ca2+ triggers rapid spreading of human neutrophils adherent via integrin engagement. Journal of Cell Science 111(15), pp. 2209-2215.
• Pettit, E. J. and Hallett, M. B. 1998. NO DOI! Two distinct Ca2+ storage and release sites in human neutrophils. Journal of leukocyte biology 63(2), pp. 225-232.
• Pettit, E. J. and Hallett, M. B. 1998. Ca2+ signalling delays in neutrophils: effects of prior exposure to platelet activating factor or formyl-met-leu-phe. Cellular Signalling 10(1), pp. 49-53. (10.1016/S0898-6568(97)00073-9)

1997

• Jiang, W. G.et al. 1997. Regulation of desmosomal cell adhesion in human tumour cells by polyunsaturated fatty acids. Clinical and Experimental Metastasis 15(6), pp. 593-602. (10.1023/A:1018435229087)
• Hallett, M. B. and Petit, E. J. 1997. The use of single image random dot stereograms for presenting 3D microscopic confocal images. Journal of Microscopy 186(3), pp. 275-278. (10.1046/j.1365-2818.1997.2130769.x)
• Pettit, E. J., Davies, E. V. and Hallett, M. B. 1997. NO DOI! The microanatomy of calcium stores in human neutrophils: relationship of structure to function. Histology and Histopathology 12(2), pp. 479-490.
• Hallett, M. B. 1997. Is "life" based on clockwork biology or quantum uncertainty?. Perspectives in Biology and Medicine 41(1), pp. 101-107. (10.1353/pbm.1997.0023)
• Al-Mohanna, F., Pettit, E. J. and Hallett, M. B. 1997. Does actin polymerization status modulate Ca2+Storage in human neutrophils? Release and coalescence of Ca2+Stores by cytochalasins. Experimental Cell Research 234(2), pp. 379-387. (10.1006/excr.1997.3596)
• Hallett, M. B. 1997. Controlling the molecular motor of neutrophil chemotaxis. Bioessays 19(7), pp. 615-621. (10.1002/bies.950190712)
• Hallett, M. B. and Pettit, E. J. 1997. Stochastic events underlie Ca2+Signalling in neutrophils. Journal of Theoretical Biology 186(1), pp. 1-6. (10.1006/jtbi.1996.0345)
• Roberts, G.et al. 1997. The timing and magnitude of Ca2+ signaling by CD32 depends on its redistribution on the cell surface. Experimental Cell Research 230(2), pp. 303-309. (10.1006/excr.1996.3416)
• Pettit, E. J. and Hallett, M. B. 1997. Pulsatile Ca2+Influx in human neutrophils undergoing CD11b/CD18 integrin engagement. Biochemical and Biophysical Research Communications 230(2), pp. 258-261. (10.1006/bbrc.1996.5931)
• Davies, E. V., Roberts, G. M. and Hallett, M. B. 1997. Spatial and temporal separation of calcium signals in myeloid cells stimulated by immune complexes. Cellular Signalling 9(6), pp. 457-462. (10.1016/S0898-6568(97)00039-9)
• Edwards, S. W. and Hallett, M. B. 1997. Seeing the wood for the trees: the forgotten role of neutrophils in rheumatoid arthritis. Immunology Today 18(7), pp. 320-324. (10.1016/S0167-5699(97)01087-6)
• Hiscox, S. E.et al. 1997. Expression of the HGF/SF Receptor, c-met, and its ligand in human colorectal cancers. Cancer Investigation 15(6), pp. 513-521. (10.3109/07357909709047592)

1996

• Jones, J.et al. 1996. Effect of inhibitors of tyrosine kinase and phospholipase C on neutrophil response to perforin attack. Immunology 89(Supp1), pp. R187-R187.
• Jiang, W. G.et al. 1996. Inhibition of membrane ruffling and ezrin translocation by gamma linolenic acid. International Journal of Oncology 9(2), pp. 279-284. (10.3892/ijo.9.2.279)
• Pettit, E. J. and Hallett, M. B. 1996. Localised and global cytosolic Ca2+ changes in neutrophils during engagement of Cd11b/CD18 integrin visualised using confocal laser scanning reconstruction. Journal of Cell Science 109(7), pp. 1689-1694.
• Jiang, W. G.et al. 1996. Inhibition of neutrophil respiratory burst and cytokine priming by γ-linolenic acid. British Journal of Surgery 83(5), pp. 659-664. (10.1002/bjs.1800830523)
• Hallett, M. B., Petit, E. J. and Davies, E. V. 1996. Capacitative Ca2+ influx and a diffusible influx factor [letter]. Biochemical Journal -London- 314(pt 3), pp. 1054-1056.
• Hallett, M. B., Pettit, E. J. and Davies, E. F. 1996. Capacitative Ca2+ influx and a diffusible influx factor. Biochemical Journal 314(3), pp. 1054-1056.
• Jiang, W. G.et al. 1996. Gamma linolenic acid inhibits tyrosine phosphorylation of focal adhesion kinase and paxillin and tumour cell matrix interaction. International Journal of Oncology 8(3), pp. 583-587. (10.3892/ijo.8.3.583)
• Davies, E. V. and Hallett, M. B. 1996. Near membrane Ca2+ changes in neutrophils. Biochemical Society Transactions 24(1), pp. 92S-92S.
• Lloyds, D., Neville, N. and Hallett, M. B. 1996. Tyrosine phosphorylation in inflammatory neutrophils. Presented at: Biochemical Society transactions 656th meeting, University College Dublin, 11–15 September 1995Biochemical Society transactions, Vol. 24. 656th Meeting Dublin Portland Press pp. 79S-79S., (10.1042/bst024079s)
• Pettit, E. J. and Hallett, M. B. 1996. Integrin triggered Ca2+ signalling in human neutrophils. Presented at: Biochemical Society Transactions 656th Meeting, University College Dublin, 11–15 September 1995Biochemical Society Transactions, Vol. 24. Biochemical Society Transactions 656th Meeting Portland Press pp. 70S-70S., (10.1042/bst024070s)
• Hallett, M. B., Davies, E. V. and Pettit, E. J. 1996. Fluorescent methods for measuring and imaging the cytosolic free Ca2+ in neutrophils. Methods: A Companion to Methods in Enzymology 9(3), pp. 591-606.
• Jiang, W. G.et al. 1996. Hepatocyte growth factor induces tyrosine phosphorylation of focal adhesion kinase (FAK) and paxillin and enhances cell-matrix interactions. Oncology Reports 3(5), pp. 819-823. (10.3892/or.3.5.819)
• Pettit, E. J. and Hallett, M. B. 1996. Temporal and spatial resolution of Ca2+Release and influx in human neutrophils using a novel confocal laser scanning mode. Biochemical and Biophysical Research Communications 229(1), pp. 109-113. (10.1006/bbrc.1996.1765)
• Lloyds, D.et al. 1996. Tyrosine phosphorylation in neutrophils from synovial fluid of patients with rheumatoid arthritis. Rheumatology 35(9), pp. 846-852. (10.1093/rheumatology/35.9.846)
• Davies, E. V. and Hallett, M. B. 1996. Near membrane Ca2+ changes resulting from store release in neutrophils: detection by FFP-18. Cell Calcium 19(4), pp. 355-362. (10.1016/S0143-4160(96)90076-7)
• Han, Z.et al. 1996. Inhibition of motility and invasion of human lung cancer cells by invasion inhibiting factor 2. Surgical Oncology 5(2), pp. 77-84. (10.1016/S0960-7404(96)80004-1)

1995

• Jiang, W. G.et al. 1995. Regulation of the expression of E-cadherin on human cancer cells by gamma-linolenic acid (GLA). Cancer Research 55, pp. 5043-5048.
• Jiang, W. G.et al. 1995. Gamma linolenic acid up-regulates e-cadherin expression in human cancer cells. British Journal of Surgery 82(11), pp. 1565-1565.
• Salaman, R. A.et al. 1995. Compression Therapy reduces neutrophil priming in venous ulcer disease. British Journal of Surgery 82(11), pp. 1553-1554.
• Jiang, W. G.et al. 1995. Expression of catenins in human cancer cells and its regulation by n-6 polyunsaturated fatty acids. Anticancer Research 15(6B), pp. 2569-2573.
• Jiang, W. G.et al. 1995. NO DOI! Regulation of the expression of E-cadherin on human cancer cells by gamma-linolenic acid (GLA). Cancer Research 55(21), pp. 5043-5048.
• Jiang, W. G.et al. 1995. Inhibition of HGF/SF-induced membrane ruffling and cell motility by transient elevation of cytosolic free Ca2+. Experimental Cell Research 220(2), pp. 424-433. (10.1006/excr.1995.1334)
• Laffafian, I. and Hallett, M. B. 1995. Does cytosolic free Ca2+ signal neutrophil chemotaxis in response to formylated chemotactic peptide?. Journal of Cell Science 108(10), pp. 3199-3205.
• Davies, E. V. and Hallett, M. B. 1995. A novel pathway for Ca2+ signalling in neutrophils by immune complexes. Immunology 85(4), pp. 538-543.
• Jiang, W. G.et al. 1995. Regulation of motility and invasion of cancer cells by human monocytic cells. Anticancer Research 15(4), pp. 1303-1310.
• Roberts, G. M., Davies, E. V. and Hallett, M. B. 1995. Slow Ca2+ waves in large myeloid cells as a result of a diffusible cytosolic factor. Journal of leukocyte biology 57(6), pp. 837-841.
• Jiang, W. G.et al. 1995. Inhibition of HGF/SF-induced tumor-cell membrane ruffling by calcium signalling. British Journal of Surgery 82(5), pp. 682-683.
• Van Den Berg, C. W.et al. 1995. Exogenous CD59 incorporated into U937 cells through its glycosyl phosphatidylinositol anchor becomes associated with signalling molecules in a time dependent manner. Biochemical Society Transactions 23(2), pp. 269S. (10.1042/bst023269s)
• Laffafian, I.et al. 1995. Complement component C9-dependent cytosolic free Ca2+ rise and recovery in neutrophils. Cell Calcium 17(4), pp. 279-286. (10.1016/0143-4160(95)90074-8)
• Jiang, W. G.et al. 1995. Inhibition of hepatocyte growth factor-induced motility and in vitro invasion of human colon cancer cells by gamma-linolenic acid. British Journal of Cancer 71(4), pp. 744-752. (10.1038/bjc.1995.145)
• Lloyds, D., Brindle, N. P. and Hallett, M. B. 1995. Priming of human neutrophils by tumour necrosis factor-alpha and substance P is associated with tyrosine phosphorylation. Immunology 84(2), pp. 220-226.
• Davies, E. V. and Hallett, M. B. 1995. A soluble cellular factor directly stimulates Ca2+ entry in neutrophils. Biochemical and Biophysical Research Communications 206(1), pp. 348-354. (10.1006/bbrc.1995.1048)
• Roberts, G. M., Hoy, T. and Hallett, M. B. 1995. The production of large 'signalling competent' myeloid cells from circulating CD34+ cells in neonatal blood. Journal of Immunological Methods 179(2), pp. 187-192. (10.1016/0022-1759(94)00284-4)
• Lloyds, D. and Hallett, M. B. 1995. Development of oxidase 'priming' in maturing HL60 cells: Correlation with protein expression and tyrosine phosphorylation. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1267(1), pp. 65-71. (10.1016/0167-4889(95)00031-M)
• Hallett, M. B. and Lloyds, D. 1995. Neutrophil priming: the cellular signals that say 'amber' but not 'green'. Immunology Today 16(6), pp. 264-268. (10.1016/0167-5699(95)80178-2)
• Hiscox, S.et al. 1995. Inhibition of cancer cell motility and invasion by interleukin-12. Clinical & Experimental Metastasis 13(5), pp. 396-404. (10.1007/BF00121916)
• van den Berg, C. W.et al. 1995. Exogenous glycosyl phosphatidylinositol-anchored CD59 associates with kinases in membrane clusters on U937 cells and becomes Ca(2+)-signaling competent. Journal of cell biology 131(3), pp. 669-677. (10.1083/jcb.131.3.669)
• Jiang, W. G.et al. 1995. Induction of tyrosine phosphorylation and translocation of ezrin by hepatocyte growth factor/scatter factor (HGF/SF). Biochemical and Biophysical Research Communications 217(3), pp. 1062-1069. (10.1006/bbrc.1995.2877)
• Lloyds, D. and Hallett, M. B. 1995. Is raf-1 the 74 kDa signalling molecule in neutrophils?. Biochemical Journal 308(3), pp. 1037. (10.1042/bj3081037)
• Pettit, E. J. and Hallett, M. B. 1995. Early Ca2+signalling events in neutrophils detected by rapid confocal laser scanning. Biochemical Journal 310(2), pp. 445-448. (10.1042/bj3100445)

1994

• PETTIT, E. and Hallett, M. 1994. Neutrophil activation and priming during engagement of CD11b/CD18 integrins. Biochemical Society Transactions 22(3), pp. 327S. (10.1042/bst022327s)
• Davies, E. V.et al. 1994. Altered Ca2+ signalling in human neutrophils from inflammatory sites. Annals of the Rheumatic Diseases 53(7), pp. 446-449. (10.1136/ard.53.7.446)
• Davies, E. V., Campbell, A. K. and Hallett, M. B. 1994. Ca2+ oscillations in neutrophils triggered by immune complexes result from Ca2+ influx. Immunology 82(1), pp. 57-62.
• Jiang, W.et al. 1994. Induction of motility and invasion by interleukin-3 on human colonic-cancer cells. British Journal of Surgery 81(5), pp. 761-761.
• Lloyds, D. and Hallett, M. B. 1994. Protein expression and development of oxidase "priming" in maturing HL60 cells. Biochemical Society Transactions 22(3), pp. 326S-326S. (10.1042/bst022326s)
• Roberts, G., Davies, E. V. and Hallett, M. B. 1994. Slow calcium waves imaged in myeloid cells derived from neonatal cord blood. Journal of leukocyte biology 55(4), pp. 461-466.
• Jiang, W. G., Puntis, M. C. A. and Hallett, M. B. 1994. Neutrophil priming by cytokines in patients with obstructive jaundice. HPB Surgery 7(4), pp. 281-289. (10.1155/1994/74202)
• Whiston, R. J.et al. 1994. Inappropriate neutrophil activation in venous disease. British Journal of Surgery 81(5), pp. 695-698. (10.1002/bjs.1800810522)
• Lloyds, D. and Hallett, M. B. 1994. Neutrophil 'priming' induced by orthovanadate: Evidence of a role for tyrosine phosphorylation. Biochemical Pharmacology 48(1), pp. 15-21. (10.1016/0006-2952(94)90218-6)
• Jiang, W. G., Puntis, M. C. A. and Hallett, M. B. 1994. Molecular and cellular basis of cancer invasion and metastasis: Implications for treatment. British Journal of Surgery 81(11), pp. 1576-1590. (10.1002/bjs.1800811107)
• Jiang, W. G., Puntis, M. C. A. and Hallett, M. B. 1994. Neutrophil priming by cytokines in patients with obstructive jaundice.. HPB Surgery 7(4), pp. 281-289. (10.1155/1994/74202)

1993

• Lloyds, D. and Hallett, M. B. 1993. Tyrosine phosphorylation of proteins during "priming" of neutrophils. Biochemical Society Transactions 21(4), pp. 436S-436S. (10.1042/bst021436s)
• Petersen, M., Williams, J. D. and Hallett, M. B. 1993. Cross-linking of CD11b or CD18 signals release of localized Ca2+ from intracellular stores in neutrophils. Immunology 80(1), pp. 157-159.
• Mills, L.et al. 1993. Beta-adrenergic mobilization of Ca2+ from an intracellular store in rat submandibular acini. Biochemical Journal 293(3), pp. 691-695.
• Jiang, W. G.et al. 1993. Regulation of spreading and growth of colon cancer cells by hepatocyte growth factor. Clinical & Experimental Metastasis 11(3), pp. 235-242. (10.1007/BF00121166)
• Morgan, B. P.et al. 1993. Cross-linking of CD59 and of other glycosyl phosphatidylinositol-anchored molecules on neutrophils triggers cell activation via tyrosine kinase. European Journal of Immunology 23(11), pp. 2841-2850. (10.1002/eji.1830231118)
• Lloyds, D. and Hallett, M. B. 1993. Activation and priming of the human neutrophil oxidase response by substance P: Distinct signal transduction pathways. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1175(2), pp. 207-213. (10.1016/0167-4889(93)90024-J)
• Jiang, W. G., Puntis, M. C. A. and Hallett, M. B. 1993. Monocyte-conditioned media possess a novel factor which increases motility of cancer cells. International Journal of Cancer 53(3), pp. 426-431. (10.1002/ijc.2910530313)
• Jiang, W. G., Hallett, M. B. and Puntis, M. C. A. 1993. Hepatocyte growth factor/scatter factor, liver regeneration and cancer metastasis. British Journal of Surgery 80(11), pp. 1368-1373. (10.1002/bjs.1800801104)

1992

• Assender, J. W.et al. 1992. Inhibition of proliferation, but not of Ca2+ mobilization, by cyclic AMP and GMP in rabbit aortic smooth-muscle cells. Biochemical Journal 288(2), pp. 527-532.
• Jiang, W. G.et al. 1992. Neutrophil priming by hepatocyte growth factor, a novel cytokine. Immunology 77(1), pp. 147-149.
• Jiang, W. G., Puntis, M. and Hallett, M. B. 1992. U937 cells stimulated with opsonised zymozan particles provide a convenient laboratory source of tumour necrosis factor α. Journal of Immunological Methods 152(2), pp. 201-207. (10.1016/0022-1759(92)90141-F)
• Davies, E. V., Campbell, A. K. and Hallett, M. B. 1992. Dissociation of store release from transmembrane influx of calcium in human neutrophils. FEBS Letters 313(2), pp. 121-125. (10.1016/0014-5793(92)81426-M)

1991

• Jones, J.et al. 1991. Imaging Ca2+ changes in individual oligodendrocytes attacked by T-cell perforin. Immunology 74(4), pp. 572-577.
• Davies, E. V., Hallett, M. B. and Campbell, A. K. 1991. Localized superoxide release by neutrophils can be provoked by a cytosolic calcium 'cloud'. Immunology 73(2), pp. 228-234.
• Davies, E. V., Campbell, A. K. and Hallett, M. B. 1991. Synchronous free Ca2+ changes in individual neutrophils stimulated by leukotriene B4. FEBS Letters 291(1), pp. 135-138. (10.1016/0014-5793(91)81121-N)
• Laffafian, I., Brown, R. C. and Hallett, M. B. 1991. The production of an amine-modified derivative of 5-aminosalicylic acid by activated neutrophils Roles for myeloperoxidase and chloride ions. Biochemical Pharmacology 42(10), pp. 1869-1874. (10.1016/0006-2952(91)90583-Q)
• Davies, E. V.et al. 1991. Single cell imaging reveals abnormal intracellular calcium signals within rheumatoid synovial neutrophils. Rhuematology 30(6), pp. 443-448. (10.1093/rheumatology/30.6.443)

1990

• Petersen, M.et al. 1990. Zymosan-induced leukotriene B4 generation by human neutrophils is augmented by rhTNF-alpha but not chemotactic peptide. Immunology 70(1), pp. 75-81.
• Jones, J., Hallett, M. B. and Morgan, B. P. 1990. Reversible cell damage by T-cell perforins. Calcium influx and propidium iodide uptake into K562 cells in the absence of lysis. Biochemical Journal 267(2), pp. 303-307.
• al-Mohanna, F. A. and Hallett, M. B. 1990. NO DOI!! Actin polymerization in neutrophils is triggered without a requirement for a rise in cytoplasmic Ca2+. Biochemical Journal 266(3), pp. 669-674.
• Hallett, M. B., Dormer, R. L. and Campbell, A. K. 1990. Cytoplasmic free calcium: measurement and manipulation in living cells. In: Siddle, K. and Hutton, J. C. eds. Peptide hormones: a practical approach. Practical Approach Series Vol. 71. Oxford: IRL Press, pp. 115-150.
• Williams, J. G., Hughes, L. E. and Hallett, M. B. 1990. Toxic oxygen metabolite production by circulating phagocytic cells in inflammatory bowel disease. Gut 31(2), pp. 187-193. (10.1136/gut.31.2.187)
• Al-Mohanna, F. and Hallett, M. B. 1990. 'Clamping' actin in polymerized form in electropermeabilized neutrophils inhibits oxidase activation. Biochemical and Biophysical Research Communications 169(3), pp. 1222-1228. (10.1016/0006-291X(90)92027-W)
• Hallett, M. B., Davies, E. V. and Campbell, A. K. 1990. Oxidase activation in individual neutrophils is dependent on the onset and magnitude of the Ca2+ signal. Cell Calcium 11(10), pp. 655-663. (10.1016/0143-4160(90)90020-U)

1989

• Cooke, E., Al-Mohanna, F. A. and Hallett, M. B. 1989. Ca2+-dependent and independent mechanisms in neutrophil activation; roles of kinase C, diacylglycerol, and unidentified intracellular messengers. In: Hallett, M. B. ed. The neutrophil; cellular biochemistry and physiology. Boca Raton: CRC Press, pp. 219-242.
• Hallett, M. B. 1989. The unpredictability of cellular behavior: trivial or of fundamental importance to cell biology?. Perspectives in Biology and Medicine 33(1), pp. 110-119. (10.1353/pbm.1990.0041)
• Williams, J. and Hallett, M. B. 1989. The reaction of 5-amino-salicylic acid with hypochlorite. Biochemical Pharmacology 38(1), pp. 149-154. (10.1016/0006-2952(89)90161-5)
• Williams, J. G. and Hallett, M. B. 1989. Effect of sulphasalazine and its active metabolite, 5-amino-salicylic acid, on toxic oxygen metabolite production by neutrophils. Gut 30(11), pp. 1581-1587. (10.1136/gut.30.11.1581)
• Srivastava, E. D., Hallett, M. B. and Rhodes, J. 1989. Effect of nicotine and cotinine on the production of oxygen free radicals by neutrophils in smokers and non-smokers. Human & Experimental Toxicology 8(6), pp. 461-463. (10.1177/096032718900800605)

1988

• Williams, J. G. and Hallett, M. B. 1988. Increased production of oxygen radicals by circulating monocytes in inflammatory bowel-disease evidence of activation. British Journal of Surgery 75(12), pp. 1269-1269.
• Zhang, L., Roberts, G. M. and Hallett, M. . B. 1988. Diphenyliodonium-sensitive killing of K652 tumor-cells by blood mononuclear cells. Biochemical Society Transactions 16(5), pp. 902-902.
• Williams, J. G. and Hallett, M. B. 1988. Flourimetric determination of hypochlorite scavenging by 5amino salicyclic-acid (5ASA). Gut 29(10), pp. A1437-A1437.
• Williams, J. G. and Hallett, M. B. 1988. The mode of action of sulphasalazine and 5-aminosalicyclic acid-inhibition of oxygen radical production by neutrophils. British Journal of Surgery 75(6), pp. 600-601.
• Al-Mohanna, F. A. and Hallett, M. B. 1988. The use of fura-2 to determine the relationship between cytoplasmic free Ca2+ and oxidase activation in rat neutrophils. Cell Calcium 9(1), pp. 17-26. (10.1016/0143-4160(88)90034-6)

1987

• Patel, A. K., Hallett, M. B. and Campell, A. K. 1987. Threshold responses in production of reactive oxygen metabolites in individual neutrophils detected by flow cytometry and microfluorimetry. Biochemical Journal 248(1), pp. 173-180.
• Al-Mohanna, F. and Hallett, M. B. 1987. Actin polymerization modifies stimulus-oxidase coupling in rat neutrophils. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 927(3), pp. 366-371. (10.1016/0167-4889(87)90101-7)
• Al-Mohanna, F., Ohishi, I. and Hallett, M. B. 1987. Botulinum C2 toxin potentiates activation of the neutrophil oxidase Further evidence of a role for actin polymerization. FEBS Letters 219(1), pp. 40-44. (10.1016/0014-5793(87)81187-0)
• Cooke, E., Al-Mohanna, F. A. and Hallett, M. B. 1987. Diacylglycerol kinase inhibitor, R59022, potentiates neutrophil oxidase activation by Ca2+-dependent stimuli. Biochemical Pharmacology 36(20), pp. 3459-3462. (10.1016/0006-2952(87)90326-1)

1986

• Horgan, K.et al. 1986. Tamoxifen inhibition of neutrophil oxidase activation - a mechanism of antitumor action. British Journal of Surgery 73(6), pp. 492-492.
• Horgan, K.et al. 1986. Tamoxifen inhibition of protein kinase C. European Journal of Cancer and Clinical Oncology 22(6), pp. 731-731. (10.1016/0277-5379(86)90233-6)
• Cooke, E. and Hallett, M. B. 1986. Retinoids interact with the mechanism of neutrophil oxidase activation. Biochemical Society Transactions 14(5), pp. 954-955.
• Hallett, M. B., Edwards, S. W. and Campbell, A. K. 1986. Control of oxygen production by polymorphonuclear leukocytes monitored by luminol-dependent chemiluminescence: the roles of intracellular calcium, oxygen concentration and redox components. In: Van Dyke, K. ed. Cellular chemiluminescence. Boca Raton: CRC Press, pp. 173-192.
• Shandall, A. A.et al. 1986. Colonic healing: A role for polymorphonuclear leucocytes and oxygen radical production. British Journal of Surgery 73(3), pp. 225-228. (10.1002/bjs.1800730325)
• Lowndes, R. H. and Hallett, M. B. 1986. A versatile light microscope heating stage for biological temperatures. Journal of Microscopy 142(3), pp. 371-374. (10.1111/j.1365-2818.1986.tb04292.x)
• Horgan, K.et al. 1986. Inhibition of protein kinase C mediated signal transduction by tamoxifen. Biochemical Pharmacology 35(24), pp. 4463-4465. (10.1016/0006-2952(86)90764-1)

1985

• Cooke, E. and Hallett, M. B. 1985. NO DOI!! The role of C-kinase in the physiological activation of the neutrophil oxidase. Evidence from using pharmacological manipulation of C-kinase activity in intact cells. Biochemical Journal 232(2), pp. 323-327.
• Cooke, E., Almohanna, F. and Hallett, M. B. 1985. The role of microfilaments in polymorphonuclear leukocyte oxidase activation. Biochemical Society Transactions 13(6), pp. 1173-1174. (10.1042/bst0131173)
• Roberts, P. A.et al. 1985. Inhibition by adenosine of reactive oxygen metabolite production by human polymorphonuclear leucocytes. Biochemical Journal 227(2), pp. 669-674.
• Campbell, A. K., Hallett, M. B. and Weeks, I. 1985. Chemiluminescence as an analytical tool in cell biology and medicine. In: Glick, D. ed. Methods in biochemical analysis., Vol. 31. New York: Wiley, pp. 317-416., (10.1002/9780470110522.ch7)
• Dormer, R. L., Hallett, M. B. and Campbell, A. K. 1985. Measurement of intracellular free calcium: Importance during activation and injury of small cells. In: Parrat, J. R. ed. Control and manipulation of calcium movements: a Biological Council symposium. New York: Raven Press, pp. 1-27.
• Campbell, A. K., Dormer, R. L. and Hallett, M. B. 1985. Coelenterate photoproteins as indicators of cytoplasmic free Ca2+ in small cells. Cell Calcium 6(1-2), pp. 69-82. (10.1016/0143-4160(85)90035-1)
• Hallett, M. B., Shandall, A. and Young, H. L. 1985. Mechanism of protection against ?reperfusion injury? by aprotinin Roles of polymorphonuclear leucocytes and oxygen radicals. Biochemical Pharmacology 34(10), pp. 1757-1761. (10.1016/0006-2952(85)90646-X)
• Hallett, M. B. 1985. Quantal secretion and response lag demonstrated in single rat neutrophils. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 847(1), pp. 15-19. (10.1016/0167-4889(85)90146-6)
• Matthews, S. B.et al. 1985. No DOI! The adrenochrome pathway. A potential catabolic route for adrenaline metabolism in inflammatory disease. Advances in myocardiology 6, pp. 367-381.

1984

• Edwards, S. W., Hallett, M. B. and Campbell, A. K. 1984. Oxygen-radical production during inflammation may be limited by oxygen concentration. Biochemical Journal 217(3), pp. 851-854.
• Hallett, M. B. and Campbell, A. K. 1984. Is intracellular Ca2+ the trigger for oxygen radical production by polymorphonuclear leucocytes?. Cell Calcium 5(1), pp. 1-19. (10.1016/0143-4160(84)90150-7)

1983

• Hallett, M. B. and Campbell, A. K. 1983. Direct measurement of intracellular free Ca2+ in rat peritoneal macrophages: correlation with oxygen-radical production. Immunology 50(3), pp. 487-495.
• Hallett, M. B. and Campbell, A. K. 1983. Two distinct mechanisms for stimulation of oxygen-radical production by polymorphonuclear leucocytes. Biochemical Journal 216(2), pp. 459-465.
• Campbell, A. K. and Hallett, M. B. 1983. Measurement of intracellular calcium ions and oxygen radicals in polymorphonuclear leucocyte-erythrocyte ‘ghost’ hybrids. The Journal of Physiology 338(1), pp. 537-550. (10.1113/jphysiol.1983.sp014688)
• Edwards, S. W.et al. 1983. Decrease in apparent Km for oxygen after stimulation of respiration of rat polymorphonuclear leukocytes. FEBS Letters 161(1), pp. 60-64. (10.1016/0014-5793(83)80730-3)

1982

• Hallett, M. B. and Campbell, A. 1982. Applications of coelenterate luminescent protein.. In: Kricka, L. J. and Clark, T. J. eds. Clinical and biochemical luminescence. New York: Marcel Dekker, pp. 89-133.

1979

• Campbell, A. K. and Hallett, M. B. 1979. Luminescence in cells and vesicles isolated from the hydroid Obelia geniculata [proceedings]. The Journal of Physiology 287, pp. 4P-5P.

1978

• Dormer, R. L., Hallett, M. B. and Campbell, A. K. 1978. The incorporation of the calcium-activated photoprotein into isolated rat fat-cells by liposome-cell fusion [proceedings]. Biochemical Society Transactions 6(3), pp. 570-572.

1977

• Foreman, J. C., Hallett, M. B. and Mongar, J. L. 1977. The relationship between histamine secretion and 45 calcium-uptake by mast cells. The Journal of Physiology 271(1), pp. 193-214. (10.1113/jphysiol.1977.sp011996)
• Foreman, J. C., Hallett, M. B. and Mongar, J. L. 1977. Movement of strontium ions into mast cells and its relationship to the secretory response. The Journal of Physiology 271(1), pp. 233-251. (10.1113/jphysiol.1977.sp011998)
• Foreman, J. C., Hallett, M. B. and Mongar, J. L. 1977. Site of action of the antiallergic drugs cromoglycate and doxantrazole [proceedings]. British Journal of Pharmacology 59(3), pp. 473P-474P.
• Foreman, J. C., Hallett, M. B. and Mongar, J. L. 1977. Strontium ions as a probe for the role of alkaline-earth metal ions in histamine secretion [proceedings]. Biochemical Society Transactions 5(4), pp. 879-883.

1975

• Foreman, J. C., Hallett, M. B. and Mongar, J. L. 1975. Proceedings: 45-Calcium uptake in rat peritoneal mast cells. British Journal of Pharmacology 55(2), pp. 283P-284P.