Yr Athro Arianna Di Florio

2024

• Song, J. et al. 2024. Key subphenotypes of bipolar disorder are differentially associated with polygenic liabilities for bipolar disorder, schizophrenia, and major depressive disorder. Molecular Psychiatry (10.1038/s41380-024-02448-1)
• Perry, A., Gordon-Smith, K., Lewis, K., Di Florio, A., Craddock, N., Jones, L. and Jones, I. 2024. Perinatal sleep disruption and postpartum psychosis in bipolar disorder: Findings from the UK BDRN Pregnancy Study. Journal of affective disorders 346, pp. 21-27. (10.1016/j.jad.2023.11.005)

2023

• Yang, J. M. K. et al. 2023. Postpartum psychosis: a public involvement perspective across three continents. Archives of Women's Mental Health 26, pp. 831-837. (10.1007/s00737-023-01347-8)
• Bramante, A. and Di Florio, A. 2023. A case – Control study of filicide/infanticide in 90 mothers. Archives of Women's Mental Health (10.1007/s00737-023-01401-5)
• Jonsson, L. et al. 2023. Not all bipolar disorder outcomes are created equal: Occupational dysfunction and hospital admissions associate with different polygenic profiles. The American Journal of Psychiatry
• Carr, C. et al. 2023. Sleep and postpartum psychosis: a narrative review of the existing literature. Journal of Clinical Medicine 12(24), article number: 7550. (10.3390/jcm12247550)
• Guintivano, J. et al. 2023. Meta-analyses of genome-wide association studies for postpartum depression. The American Journal of Psychiatry 180(12), pp. 884-895. (10.1176/appi.ajp.20230053)
• Di Florio, A., Apsey, C. and Eisenlohr-Moul, T. 2023. Etiologic studies of premenstrual disorders require prospective confirmation of affective cyclicity. JAMA Psychiatry 80(11), article number: 1175. (10.1001/jamapsychiatry.2023.3287)
• Munk-Olsen, T. et al. 2023. Postpartum and non-postpartum depression: a population-based matched case-control study comparing polygenic risk scores for severe mental disorders. Translational Psychiatry 13, article number: 346. (10.1038/s41398-023-02649-2)
• Munk-Olsen, T., Di Florio, A., Bergink, V., Agerbo, E., Madsen, K. B., Petersen, L. V. and Liu, X. 2023. Genetic liability to bipolar disorder and onset of postpartum mental disorders. BMJ Mental Health 26(1), article number: e300835. (10.1136/bmjment-2023-300835)
• Allardyce, J. et al. 2023. Specificity of polygenic signatures across symptom dimensions in bipolar disorder: an analysis of UK Bipolar Disorder Research Network data. The Lancet Psychiatry 10(8), pp. 623-631. (10.1016/S2215-0366(23)00186-4)
• Lewis, K. et al. 2023. The dynamic interplay between sleep and mood: an intensive longitudinal study of individuals with bipolar disorder. Psychological Medicine 53(8), pp. 3345-3354. (10.1017/S0033291721005377)
• Vaiphei, K., Yaresheemi, S., Yang, J. M. K., Di Florio, A., Chandra, P. S. and Thippeswamy, H. 2023. Formation of a stakeholder group of women with a lived experience of Post-partum Psychoses (PP) – Experience from a perinatal psychiatry service in India. Asian Journal of Psychiatry 84, article number: 103592. (10.1016/j.ajp.2023.103592)
• Casanova Dias, M. et al. 2023. Borderline personality traits are differently associated with postpartum psychosis and postpartum depression episodes in women with bipolar disorder. Journal of Affective Disorders 328, pp. 81-86. (10.1016/j.jad.2023.01.124)

2022

• Lewis, K. J. et al. 2022. Mental health prior to and during the COVID-19 pandemic in individuals with bipolar disorder: Insights from prospective longitudinal data. Bipolar Disorders 24(6), pp. 658-666. (10.1111/bdi.13204)
• Richards, A. et al. 2022. Genetic liabilities differentiating bipolar disorder, schizophrenia and major depression and phenotypic heterogeneity in bipolar disorder. JAMA Psychiatry 79(10), pp. 1032-1039. (10.1001/jamapsychiatry.2022.2594)
• Palmer, D. et al. 2022. Exome sequencing in bipolar disorder reveals AKAP11 as a risk gene shared with schizophrenia. Nature Genetics (10.1038/s41588-022-01034-x)

2021

• Di Florio, A. et al. 2021. Post-partum psychosis and its association with bipolar disorder in the UK: a case-control study using polygenic risk scores. The Lancet Psychiatry 8(12), pp. 1045-1052. (10.1016/S2215-0366(21)00253-4)
• Kalman, J. L. et al. 2021. Characterisation of age and polarity at onset in bipolar disorder. The British Journal of Psychiatry 219(6), pp. 659-669. (10.1192/bjp.2021.102)
• Perry, A., Gordon-Smith, K., Di Florio, A., Craddock, N., Jones, L. and Jones, I. 2021. Mood episodes in pregnancy and risk of postpartum recurrence in bipolar disorder: The Bipolar Disorder Research Network Pregnancy Study. Journal of Affective Disorders 294, pp. 714-722. (10.1016/j.jad.2021.07.067)
• Jia, X. et al. 2021. Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder. Molecular Psychiatry 26, pp. 5239-5250. (10.1038/s41380-020-01006-9)
• Clifton, N. E. et al. 2021. Developmental profile of psychiatric risk associated with voltage-gated cation channel activity. Biological Psychiatry 90(6) (10.1016/j.biopsych.2021.03.009)
• Legge, S. et al. 2021. Associations between schizophrenia polygenic liability, symptom dimensions, and cognitive ability in schizophrenia. JAMA Psychiatry 78(10), pp. 1143-1151. (10.1001/jamapsychiatry.2021.1961)
• Clifton, N. E. et al. 2021. Genetic association of FMRP targets with psychiatric disorders. Molecular Psychiatry 26, pp. 2977-2990. (10.1038/s41380-020-00912-2)
• Saunders, K. E. A. et al. 2021. The influence of borderline personality traits on clinical outcomes in bipolar disorder. Bipolar Disorders 23(4), pp. 368-375. (10.1111/bdi.12978)
• Mullins, N. et al. 2021. Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature Genetics 53, pp. 817-829. (10.1038/s41588-021-00857-4)

2020

• Gordon-Smith, K. et al. 2020. Patterns and clinical correlates of lifetime alcohol consumption in women and men with bipolar disorder: Findings from the UK Bipolar Disorder Research Network. Bipolar Disorders 22(7), pp. 731-738. (10.1111/bdi.12905)
• Marwaha, S. et al. 2020. Explaining why childhood abuse is a risk factor for poorer clinical course in bipolar disorder: a path analysis of 923 people with bipolar I disorder. Psychological Medicine 50(14), pp. 2346-2354. (10.1017/S0033291719002411)
• Soda, T. et al. 2020. International consortium on the genetics of electroconvulsive therapy and severe depressive disorders (Gen-ECT-ic). European Archives of Psychiatry and Clinical Neuroscience 270, pp. 921-932. (10.1007/s00406-019-01087-w)
• Sharma, V. et al. 2020. Primacy of (hypo) mania in the postpartum period: a concept worth considering. Bipolar Disorders 22(6), pp. 553-555. (10.1111/bdi.12988)
• Akingbuwa, W. A. et al. 2020. Genetic associations between childhood psychopathology and adult depression and associated traits in 42 998 individuals. JAMA Psychiatry 77(7), pp. 715-728. (10.1001/jamapsychiatry.2020.0527)
• Lewis, K. J. et al. 2020. Comparison of genetic liability for sleep traits among individuals with Bipolar Disorder I or II and control participants. JAMA Psychiatry 77(3), pp. 303-310. (10.1001/jamapsychiatry.2019.4079)
• Gordon-Smith, K. et al. 2020. Symptom profile of postpartum and non-postpartum manic episodes in bipolar I disorder: a within-subjects study. Psychiatry Research 284, article number: 112748. (10.1016/j.psychres.2020.112748)
• Perry, A., Gordon-Smith, K., Di Florio, A., Fraser, C., Craddock, N., Jones, L. and Jones, I. 2020. Adverse childhood experiences and postpartum depression in bipolar disorder. Journal of Affective Disorders 263, pp. 661-666. (10.1016/j.jad.2019.11.042)

2019

• Luykx, J., Di Florio, A. and Bergink, V. 2019. Prevention of infanticide and suicide in the postpartum period: the importance of emergency care. JAMA Psychiatry 76(12), pp. 1221-1222. (10.1001/jamapsychiatry.2019.1929)
• Lee, P. H. et al. 2019. Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders. Cell 179(7), pp. 1469-1482.e11. (10.1016/j.cell.2019.11.020)
• Perry, A. et al. 2019. Postpartum psychosis in bipolar disorder: no evidence of association with personality traits, cognitive style or affective temperaments. BMC Psychiatry 19(1), article number: 395. (10.1186/s12888-019-2392-0)
• Mistry, S., Escott-Price, V., Di Florio, A., Smith, D. and Zammit, S. 2019. Investigating associations between genetic risk for bipolar disorder and cognitive functioning in childhood. Journal of Affective Disorders 259, pp. 112-120. (10.1016/j.jad.2019.08.040)
• Serra, F. et al. 2019. Agitated depression in bipolar disorder. Bipolar Disorders 21(6), pp. 547-555. (10.1111/bdi.12778)
• Di Florio, A. et al. 2019. Stratification of the risk of bipolar disorder recurrences in pregnancy and postpartum. British Journal of Psychiatry 213(3), pp. 542-547. (10.1192/bjp.2018.92)
• Charney, A. W. et al. 2019. Contribution of rare copy number variants to bipolar disorder risk Is limited to schizoaffective cases. Biological Psychiatry 86(2), pp. 110-119. (10.1016/j.biopsych.2018.12.009)
• Stahl, E. A. et al. 2019. Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics 51, pp. 793-803. (10.1038/s41588-019-0397-8)
• Yu, H., Chapman, B., Di Florio, A., Eischen, E., Gotz, D., Jacob, M. and Blair, R. H. 2019. Bootstrapping estimates of stability for clusters, observations and model selection. Computational Statistics 34(1), pp. 349-372. (10.1007/s00180-018-0830-y)
• Mistry, S., Escott-Price, V., Di Florio, A., Smith, D. J. and Zammit, S. 2019. Genetic risk for bipolar disorder and psychopathology from childhood to early adulthood. Journal of Affective Disorders 246, pp. 633-639. (10.1016/j.jad.2018.12.091)
• Clifton, N. E. et al. 2019. Dynamic expression of genes associated with schizophrenia and bipolar disorder across development. Translational Psychiatry 9, article number: 74. (10.1038/s41398-019-0405-x)

2018

• Hidalgo-Mazzei, D. et al. 2018. Treatment-resistant and Multi-therapy resistant criteria for bipolar depression: consensus definition. British Journal of Psychiatry (10.1192/bjp.2018.257)
• Di Florio, A., Alexander, D., Schmidt, P. J. and Rubinow, D. R. 2018. Progesterone and plasma metabolites in women with and in those without premenstrual dysphoric disorder. Depression and Anxiety 35(12), pp. 1168-1177. (10.1002/da.22827)
• Munk-Olsen, T. et al. 2018. Maternal and infant outcomes associated with lithium use in pregnancy. Lancet Psychiatry 5(8), pp. 644-652. (10.1016/S2215-0366(18)30180-9)
• Ruderfer, D. M. et al. 2018. Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes. Cell 173(7), pp. 1705-1715.e16. (10.1016/j.cell.2018.05.046)
• Leonenko, G. et al. 2018. A data-driven investigation of relationships between bipolar psychotic symptoms and schizophrenia genome-wide significant genetic loci. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 177(4), pp. 468-475. (10.1002/ajmg.b.32635)
• Meltzer-Brody, S. et al. 2018. Adverse life events increase risk for postpartum psychiatric episodes: a population based epidemiologic study. Depression and Anxiety 35(2), pp. 160-167. (10.1002/da.22697)
• Allardyce, J. et al. 2018. Association between schizophrenia-related polygenic liability and the occurrence and level of mood-incongruent psychotic symptoms in bipolar disorder. JAMA Psychiatry 75(1), pp. 28-35. (10.1001/jamapsychiatry.2017.3485)
• Lewis, K. et al. 2018. Mania triggered by sleep loss and risk of postpartum psychosis in women with bipolar disorder. Journal of Affective Disorders 225, pp. 624-629. (10.1016/j.jad.2017.08.054)

2017

• Green, E. K. et al. 2017. Genome-wide significant locus for Research Diagnostic Criteria Schizoaffective Disorder Bipolar type. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 174(8), pp. 767-771. (10.1002/ajmg.b.32572)
• Lewis, K., Gordon-Smith, K., Forty, L., Di Florio, A., Craddock, N., Jones, L. and Jones, I. 2017. Sleep loss as a trigger of mood episodes in bipolar disorder: individual differences based on diagnostic subtype and gender. British Journal of Psychiatry 211(3), pp. 169-174. (10.1192/bjp.bp.117.202259)
• Lara-Cinisomo, S., McKenney, K., Di Florio, A. and Meltzer-Brody, S. 2017. Associations between postpartum depression, breastfeeding, and oxytocin levels in Latina mothers. Breastfeeding Medicine 12(7), pp. 436-442. (10.1089/bfm.2016.0213)
• Allardyce, J. et al. 2017. Psychosis and the level of mood incongruence in Bipolar Disorder are related to genetic liability for Schizophrenia. [Online]. bioRxiv. Available at: http://dx.doi.org/10.1101/160119
• Witt, S. H. et al. 2017. Genome-wide association study of borderline personality disorder reveals genetic overlap with the bipolar disorder, schizophrenia and major depression. Translational Psychiatry 7, article number: e1155.
• Ferguson, E. H., Di Florio, A., Pearson, B., Putnam, K. T., Girdler, S., Rubinow, D. R. and Meltzer-Brody, S. 2017. HPA axis reactivity to pharmacologic and psychological stressors in euthymic women with histories of postpartum versus major depression. Archives of Women's Mental Health 20(3), pp. 411-420. (10.1007/s00737-017-0716-y)
• Putnam, K. T. et al. 2017. Clinical phenotypes of perinatal depression and time of symptom onset: analysis of data from an international consortium. The Lancet Psychiatry 4(6), pp. 477-485. (10.1016/S2215-0366(17)30136-0)
• Di Florio, A. et al. 2017. The impact of education, country, race and ethnicity on the self-report of postpartum depression using the Edinburgh Postnatal Depression Scale. Psychological Medicine 47(5), pp. 787-799. (10.1017/S0033291716002087)
• Charney, A. W. et al. 2017. Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder. Translational Psychiatry 7(1), pp. e993. (10.1038/tp.2016.242)

2016

• Perry, A., Gordon-Smith, K., Di Florio, A., Forty, E., Craddock, N. J., Jones, L. and Jones, I. R. 2016. Adverse childhood life events and postpartum psychosis in bipolar disorder. Journal of affective disorders 205, pp. 69-72. (10.1016/j.jad.2016.06.061)
• Munk-Olsen, T. et al. 2016. Perinatal psychiatric episodes: a population-based study on treatment incidence and prevalence. Translational Psychiatry 6, article number: e919. (10.1038/tp.2016.190)
• Song, J. et al. 2016. Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder. Molecular Psychiatry 2016, pp. 1290-1297. (10.1038/mp.2015.165)
• Kimmel, M. C., Lara-Cinisomo, S., Melvin, K., Di Florio, A., Brandon, A. and Meltzer-Brody, S. 2016. Treatment of severe perinatal mood disorders on a specialized perinatal psychiatry inpatient unit. Archives of Women's Mental Health 19, article number: 645. (10.1007/s00737-016-0599-3)
• Di Florio, A., Munk-Olsen, T. and Bergink, V. 2016. The birth of a psychiatric orphan disorder: postpartum psychosis [Correspondence]. The Lancet Psychiatry 3(6), pp. 502. (10.1016/S2215-0366(16)30037-2)

2015

• Singh, S. et al. 2015. Affective temperaments and concomitant alcohol use disorders in bipolar disorder. Journal of affective disorders 186, pp. 226-231. (10.1016/j.jad.2015.07.027)
• Di Florio, A. and Meltzer-Brody, S. 2015. Is postpartum depression a distinct disorder?. Current Psychiatry Reports 17(10), article number: 76. (10.1007/s11920-015-0617-6)
• Di Florio, A., Morgan, H., Jones, L., Forty, E., Gordon-Smith, K., Craddock, N. J. and Jones, I. R. 2015. Smoking and postpartum psychosis. Bipolar Disorders 17(5), pp. 572-573. (10.1111/bdi.12314)
• Castro, V. M. et al. 2015. Validation of electronic health record phenotyping of bipolar disorder cases and controls. American Journal of Psychiatry 172(4), pp. 363-372. (10.1176/appi.ajp.2014.14030423)
• Di Florio, A., Jones, L., Forty, E., Gordon-Smith, K., Craddock, N. J. and Jones, I. R. 2015. Bipolar disorder, miscarriage, and termination. Bipolar Disorders 17(1), pp. 102-105. (10.1111/bdi.12217)
• Pigato, G., Piazzon, G. V. M., Di Florio, A., Ermani, M., Toffanin, T. and Perini, G. I. 2015. Early hyperprolactinaemia in acute psychiatric inpatients: a cross-sectional study. Journal of Psychopathology 21(3), pp. 226-230.

2014

• Di Florio, A., Jones, L., Forty, E., Gordon-Smith, K., Craddock, N. J. and Jones, I. R. 2014. Postpartum bipolar depression in a clinical sample of 1721 parous women with mood disorders [Conference Abstract]. Bipolar Disorders 16(S1), pp. 62-62. (10.1111/bdi.12188)
• Di Florio, A., Craddock, N. J. and van den Bree, M. B. 2014. Alcohol misuse in bipolar disorder. A systematic review and meta-analysis of comorbidity rates. European Psychiatry 29(3), pp. 117-24. (10.1016/j.eurpsy.2013.07.004)
• Di Florio, A. et al. 2014. Mood disorders and parity - A clue to the aetiology of the postpartum trigger. Journal of affective disorders 152-15, pp. 334-339. (10.1016/j.jad.2013.09.034)

2013

• Di Florio, A. et al. 2013. Perinatal episodes across the mood disorder spectrum. JAMA Psychiatry 70(2), pp. 168-175. (10.1001/jamapsychiatry.2013.279)
• Di Florio, A., Smith, S. and Jones, I. R. 2013. Postpartum psychosis. The Obstetrician & Gynaecologist 15(3), pp. 145-150. (10.1111/tog.12041)
• Di Florio, A. and Craddock, N. J. 2013. The genomics revolution in psychiatry: a lesson from bipolar disorder. Dusunen Adam 26(2), pp. 119-121. (10.5350/DAJPN20132602001)

2012

• Di Florio, A. 2012. Bipolar disorder in pregnancy and the postpartum. PhD Thesis, Cardiff University.

2011

• Smith, D. J. et al. 2011. Beating bipolar: exploratory trial of a novel internet-based psychoeducational treatment for bipolar disorder. Bipolar Disorders 13(5-6), pp. 571-577. (10.1111/j.1399-5618.2011.00949.x)

2010

• Di Florio, A. and Jones, I. R. 2010. Is sex important? Gender differences in bipolar disorder. International Review of Psychiatry 22(5), pp. 437-452. (10.3109/09540261.2010.514601)
• Di Florio, A. et al. 2010. Affective temperaments across the bipolar-unipolar spectrum: examination of the TEMPS-A in 927 patients and controls. Journal of affective disorders 123(1-3), pp. 42-51. (10.1016/j.jad.2009.09.020)

2009

• Pigato, G., Toffanin, T., Ferri, G., Di Florio, A., Giannunzio, V. and Perini, G. 2009. Studio naturalistico di confronto tra due strategie di dosaggio iniziale di duloxetina in un contesto clinico “real world". Rivista di Psichiatria 44(6), pp. 1-9. (10.1708/468.5538)

2008

• Perini, G. I., Di Florio, A. and Pavan, C. 2008. Major depressive disorders and coronary artery disease: a review on common pathophysiological pathways. Clinical Neuropsychiatry 5(3), pp. 151-161.