Ewch i’r prif gynnwys
Dr Ian Brewis

Dr Ian Brewis

Senior Lecturer

Yr Ysgol Meddygaeth

Email:
brewisia@cardiff.ac.uk
Telephone:
+44 (0)29 2068 8648
Location:
Adeilad Henry Wellcome ar gyfer Ymchwil Biofeddygol, Ysbyty Athrofaol Cymru, Parc y Mynydd Bychan, Caerdydd, CF14 4XN

I am a Senior Lecturer and my main responsibilities are in my roles as Central Biotechnology Services (CBS) Operational Director and the MSc Medical Research and Innovation Programme Director.

Since 2011 I have been CBS Operational Director (0.7FTE). CBS (http://medicine.cf.ac.uk/cbs) is an ISO 9001:2015 certified Cardiff University Technology Facility based in the College of Biomedical and Life Sciences with a remit across the entire College. We provide genomics and bioinformatics, proteins and diagnostics and cell analysis/imaging platforms, services, training and expertise to local researchers and external organisations. Externally we also offer opportunities for hosting companies and provide laboratory facilities, technological support, academic consultancy and access to other university resources. Options for contract research and managed services are backed up by our proven track record of working with not-for-profit organisations, start-ups, SMEs and corporates. Please contact us at cbsadmin@cardiff.ac.uk and you can follow us on Twitter @CentralBioServ.

Since Oct 2016 I have been the MSc Medical Research and Innovation Programme Director (0.2FTE) with a further remit to co-ordinate the delivery of short courses in Clinical Innovation internally and to external organisations. I have a wide-ranging teaching portfolio (0.1FTE) and I am the School of Medicine C21 Divisional Teaching Lead for Clinical Innovation and the Postgraduate Research (PGR) Representative for Clinical Innovation

I have experience as an External Examiner for five Masters Programmes at three Russell Group universities: University of Liverpool MRes and MSc in Advanced BIological Sciences (since 2017); Queen Mary University of London MSc Bioinformatics Programme (since 2014); University of York MSc Bioscience Technology Programme (2012-2015) and MSc Post Genomic Biology Programme (2014-2015). I am also an External Examiner at Nottingham Trent University for the MBiol Biochemistry, BSc Biochemistry and BSc Biological Sciences (Biochemistry and Microbiology) Programmes (since 2017). From a research perspective I have served as an External Examiner for 9 PhD theses and 1 MSc thesis at research intensive universities. Formerly in my spare time I was also an Associate Lecturer at the Open University (2010-2017).

From 2010-Dec 2016 I was the MSc Bioinformatics Programme Director (0.3FTE) and my involvement goes back to 2004 when I was closely involved with the establishment of the Programme. Formerly I was the Bioinformatics and Biostatistics Committee Teaching and Training Lead (to Dec 2016). I was recruited to Cardiff in 2003 as part of a large Welsh Assembly Government funded initiative to set up the Biostatistics and Bioinformatics Unit (BBU). I was also tasked to achieve funding, establish and lead a new Proteomics Facility.

This was successful and, as CBS Proteomics Facility Academic Lead, I was responsible for a wide portfolio of projects in extended collaborations with many Cardiff researchers and external clients. Our biggest external contract was with Ovasort Ltd and formerly I was also Scientific Director for the company. They were interested in sperm-based sex-selection in livestock (and to a lesser extent cancer biomarker discovery) and embedded in our laboratories from 2005-2009. CBS Proteomics services officially discontinued in 2014 and this work is now outsourced (primarily to the University of Bristol). Please continue to contact me for proteomics advice and to co-ordinate outsourcing services.

My main research interests are the proteomic and functional characterisation of mammalian sperm cells at fertilization which was conducted in close collaboration with Dr Bart Gadella at Utrecht University, The Netherlands for many years. My preferred career direction has resulted in my own research being a minor activity during my time in Cardiff and I am no longer independently research active. My main association with the field is now as an Editorial Board Member for the journal Reproduction (Impact Factor 3.184; since 2013) and formerly I was also an Editorial Board Member (Associate Editor) for Molecular Human Reproduction (Impact Factor 3.943; 2012-2015). 

Before Cardiff I was a Senior Research Fellow at the University of Birmingham and Birmingham NHS Assisted Conception Unit (2000-2003) and a Postdoctoral Research Associate at the University of Sheffield (1993-2000) and primarily focused on molecular aspects of sperm function. These varied roles also included a wide range of other research projects in reproduction and several years working on commercial projects (and in particular a male fertility test and a study using human stem cell technologies).

My PhD (1994) on the biochemistry of mammalian glycolipid anchors was conducted as a Research Assistant at the University of Leeds and also involved spending extended time with collaborators at the University of Dundee. Prior to this I was a Research Assistant at the University of York (1989-1990) where I investigated the biochemistry of the Fallopian tube. Lastly I also studied for my first degree at the University of York and graduated in 1989 with a BSc (Hons) in Biology (Cell Biology and Biochemistry). 

EDUCATION AND QUALIFICATIONS

1994    The University of Leeds, PhD in Biochemistry

1989    The University of York, BSc (Hons) Biology (Cell Biology and Biochemistry)

CAREER OVERVIEW

PRESENT CARDIFF RESPONSIBILITIES AND AFFILIATIONS

Since 2016    MSc Medical Research and Innovation Programme Director

Since 2016    Based at College level in the College of Biomedical and Life Sciences as part of the Clinical Innovation Hub

Since 2015    School of Medicine Divisional Teaching Lead for Clinical Innovation (and previously the TIME Institute)

Since 2011    School of Medicine Postgraduate Research (PGR) Representative for Clinical Innovation (and previously the TIME Institute)

Since 2011    Central Biotechnology Services (CBS) Operational Director

Since 2008    Senior Lecturer

PREVIOUS CARDIFF RESPONSIBILITIES  AND AFFILIATIONS

2013-2016    Bioinformatics and Biostatistics Committee Teaching and Training Lead

2010-2016    MSc Bioinformatics Programme Director

2011-2015    TIME (Translation, Innovation, Methodologies and Engagement) Institute

2004-2015    Cardiff University School of Medicine

2006-2014    CBS Proteomics Facility Academic Lead

2006-2011    Department of Medical Biochemistry and Immunology and Central Biotechnology Services (CBS)

2003-2008    Lecturer at Cardiff University School of Medicine (formerly University of Wales College of Medicine)

2003-2006    Joint Head of Bioinformatics in the Biostatistics and Bioinformatics Unit (BBU)

2003-2006    Department of Medical Biochemistry and Immunology and Department of Psychological Medicine

2003-2005    Honorary Senior Research Fellow at the University of Birmingham

2003-2004    University of Wales College of Medicine

APPOINTMENTS BEFORE CARDIFF

2000-2003    Senior Research Fellow (RA2 Lecturer B equivalent) at the University of Birmingham (Reproductive Biology and Genetics Group, School of Medicine and The Assisted Conception Unit, Birmingham Women’s Hospital)

1993-2000    Postdoctoral Research Associate (RA1A) at the University of Sheffield (Molecular Reproduction and Development Group, Department of Molecular Biology and Biotechnology and Department of Obstetrics and Gynaecology, Jessop Hospital for Women)

1990-1993    Research Assistant (RA1B) at the University of Leeds (Department of Biochemistry and Molecular Biology)

1989-1990    Research Assistant (RA1B) at the University of York (Department of Biology)

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