Mae'r cynnwys hwn ar gael yn Saesneg yn unig.
Trosolwg
Ymchil
Diddordebau ymchwil
- Understanding the mechanism of action of class iid bacteriocins
- Total chemical synthesis of proteins
- Racemic protein crystallography
Dysgu
- Laboratory demonstrator in undergraduate Organic Chemistry
- Laboratory demonstrator in postgraduate Biological Chemistry and Medicinal Chemsitry
- CH3105: Techniques and Methods in Chemistry
Traethawd ymchwil
Large Scale Production of Antibacterial Peptides by a Synthetic Biology Approach
Goruchwyliaeth
Dr Louis Luk
Research fellow
Cyhoeddiadau
2023
- Lander, A. J., Kong, Y., Jin, Y., Wu, C. and Luk, L. Y. P. 2023. Deciphering the synthetic and refolding strategy of a cysteine-rich domain in the tumor necrosis factor receptor (TNF-R) for racemic crystallography analysis and d-peptide ligand discovery. ACS Bio & Med Chem Au (10.1021/acsbiomedchemau.3c00060)
- Lander, A. J., Mercado, L. D., Li, X., Taily, I. M., Findlay, B. L., Jin, Y. and Luk, L. Y. P. 2023. Roles of inter- and intramolecular tryptophan interactions in membrane-active proteins revealed by racemic protein crystallography. Communications Chemistry 6(1), article number: 154. (10.1038/s42004-023-00953-y)
2022
- Lander, A. J., Jin, Y. and Luk, L. Y. P. 2022. D‐peptide and d‐protein technology: recent advances, challenges, and opportunities. ChemBioChem, article number: e202200537. (10.1002/cbic.202200537)
- Lander, A. 2022. D-protein and D-peptide technology in applied research. PhD Thesis, Cardiff University.
2020
- Tang, T. M. S., Cardella, D., Lander, A. J., Li, X., Escudero, J. S., Tsai, Y. and Luk, L. Y. P. 2020. Use of an asparaginyl endopeptidase for chemo-enzymatic peptide and protein labeling. Chemical Science 11(23), pp. 5881-5888. (10.1039/D0SC02023K)