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1-30 of 37 search results

Name	Qualification	Mode	Type
Molecular Biosciences Molecular Biosciences focuses on the molecular mechanisms underpinning biological function.	PhD, MPhil, MD	Full-time, Part-time	Area
Biosciences Our research ranges across the biological sciences, from the understanding of precisely how neurons grow, to the mechanisms of cancer and other diseases, the molecular basis of animal and plant development and exploring the genetics of orang-utans, elephants, pandas and other endangered species.	PhD, MPhil, MD	Full-time, Part-time	Programme
Structural analysis of receptors for insecticidal toxins Insecticidal toxins produced by bacteria such as Bacillus thuringiensis and Lysinibacillus sphaericus are the active agents in these important biological pesticides and can also be exploited in the production of insect-resistant transgenic plants.			Project
The gut microbiota continuum - what does it mean for the host? This project will explore and measure basic parameters of three groups of individuals, which fall at the extremes of this continuum and in the middle.			Project
Molecular mechanisms of phenotype determination in BNST forebrain neurons The complexity of adult brain function is largely met by the networking of a multitude of neurons, but there is also a requirement for different types of neuron.			Project
Cytoplasmic RNA regulation in cell motility This project will investigate how cytoplasmic RNA regulation impacts on cell motility and immune function, by studying conserved RNA-binding proteins and their interactions with candidate mRNAs.			Project
Developing a 3rd generation sequencing based method for identification of bacteria without culturing There are many instances in which we need to identify bacteria, but are unable to grow them in the laboratory, for example, urinary tract infections, wound infections and bacterial vaginosis.			Project
The functional proteome of the microbiome and its role in endotoxin modulation Inflammatory disease such as Inflammatory Bowel Disease and Non-alcoholic fatty liver disease, are all increasing in the global population, as are many other non-communicable diseases.			Project
Detection of outer membrane vesicles (OMVs) in common gut bacteria and fecal samples The role of bacteria and microbes in cancer has received considerable attention due to the involvement of Helicobacter pylori and viruses such as HPV, EBV and Hep B and C.			Project
Protein interactions in the regulation of a model cell differentiation program Cell differentiation programs drive the production of specialised tissues from progenitor cells during animal development.			Project
Role of the lysosome, and the lysosomal protein NPC1 in the pathogenesis and treatment of Mycobacteriumtuberculosis Tuberculosis (TB) is a chronic disease that in it’s latent form affects approximately one third of the worlds population with an estimated 10 million new cases and 1.5 million deaths per year.			Project
Firing dynamics of thalamic and cortical neural networks during absence epilepsy Epilepsy is one of the most serious and widespread neurological diseases, which affect about 1% of the population.			Project
Transcriptional landscaping in plant stem cells: from chromatin to gene regulatory networks Agriculture depends on the activity of meristems – small populations of pluripotent stem cells from which all major plant tissues and organs are produced.			Project
A Synthetic Reaction-Diffusion System for Engineering Patterning and Self-Organisation in Plant Stem Cells Reaction-diffusion systems are employed in biology to establish patterns associated with the formation of distinct tissues and organs at the multicellular scale.			Project
Plasticity of visual information processing and the consequences of neurodevelopmental disorders The aim of this project is to identify specific cellular mechanisms by which developmental or genetic defects translate into visual or neurological condition.			Project
Novel water treatments for zoonotic pathogen Cryptosporidium This interdisciplinary project will combine the novel method of water treatment using microwaves with state-of-art Cryptospordium culturing.			Project
Developmental and molecular analysis of sperm production in Drosophila This project links developmental biology and determination of cell fate, through transcriptional controls that interpret that cell fate decision and control differentiation to evolution and optimisation of reproductive function.			Project
Characterisation of microRNAs regulated by dihomo-gamma-linolenic acid in macrophages in relation to atherosclerosis Atherosclerosis, the underlying cause of myocardial infarction, stroke and peripheral vascular disease, is responsible for more deaths in the western world than any other disease with mortality increasing at a marked rate in developing countries.			Project
Examining the programming of offspring behaviour by maternal diet and abnormal maternal care There is a well-defined association between early life adversity (either prenatally or in early childhood) and significantly poorer outcomes for children.			Project
Developing plants as an expression system for mammalian ion channels The aim of this project is to develop plant expression systems for eukaryotic membrane proteins, focusing on the P2X receptor family of ATP-gated ion channels.			Project
Tackling antibiotic resistance by combining synthetic biology and nanotechnology: development of new biosensing systems This project will bridge the areas of synthetic biology and nanotechnology to address the growing problem of antimicrobial resistance (AMR).			Project
Olfactory perception and prey choice behaviour by generalist predators (Carabidae) This project combines fundamental work on a major mechanism for prey choice by predators of pests in crops with work of much wider significance for our understanding of basic perception.			Project
New approaches antimicrobial resistance detection and treatment This project aims to develop a set of proteins that can bind across a broad set of BLs for the purpose of detection and potential treatment.			Project
Gene expression regulation by RNA-binding proteins during fly development This project will employ complementary in vivo and in vitro approaches to functionally characterize nuclear and cytoplasmic PTB-containing complexes.			Project
Using human genetics to reveal novel molecular pathways involved in mediating protective skeletal responses to exercise and mechanical loading This project is intended to identify further pathways involved in mechanical loading responses of bone, which could act as additional targets for bone-forming drugs.			Project
How can we engineer more robust plants? Smart genetic screens and advanced imaging strategies to understand the cellular basis of plant growth under normal and stress conditions This project aims to study and understand molecular mechanisms that link stress to the stopping of cell division and attempt to identify mutants that can uncouple these processes.			Project
Building the molecular tool kits to exploit Burkholderia bacteria as biotechnological agents This PhD project aims to express silent gene clusters, optimally produce novel antibiotics and genetically engineer pathways to create novel products.			Project
Towards the clinical development of calcium-sensing receptor antagonists as novel therapeutics for inflammatory lung diseases G protein-coupled receptors (GPCRs) have crucial roles in almost every physiological process from cardiac function, immune responses and neurotransmission to sensory functions comprising sight, taste and smell.			Project
Understanding the dynamics and determinants of recovery of a regionally iconic wild food resource following its near-extinction due to infectious disease This is a multidisciplinary project focused on recovering regionally iconic wild food resource following its near-extinction due to infectious disease.			Project
Probing 'kiss and go'; in vivo detection of interactions with RBR in the Arabidopsis root meristem This project will develop molecular tools based on fluorescent tags to investigate the levels of bound and unbound retinoblastoma in living cells with different kinase levels by advanced imaging.			Project