Each year the School of Chemistry welcomes applicants who have secured funding from external sponsors, or who are self-funded.
Details for each project can be obtained by contacting the member of academic staff directly. Please state which project(s) you would like to be considered for on your application form.
- Physical and Chemical Basis of Enzyme Catalysis.
- Redesign of existing natural biological systems for useful purposes.
General information about Professor Allemann's research can be found via the Allemann research group blog.
- Substrate-based radical formation without organic chemical precedent.
- Free energy of interaction in enzyme/inhibitor and protein/nucleic acid complexes.
- The structure and properties of DNA and RNA containing additional nucleobases.
- Metal compounds as modulators of proteins/enzyme activities.
- Selective inhibition of AQPs by gold complexes in targeted cancer therapies.
- Metallocages, supramolecular chemistry and molecular recognition.
- Development of novel chemical biology tools to study protein functions in vivo.
- Applications of genetically incorporated unnatural amino acids in living systems.
- Developing enzyme-driven hydrogen-borrowing cascades.
- Structural and biochemical studies of protein-protein interactions involved in sepsis and immune defence, leading to the rational design of new drugs.
- Structural and NMR studies of the catalysis of DNA-repairing enzymes.
- Developing a new approach to improve the druggability of small G proteins based on the catalytic mechanisms and structural details.