Systems Immunity Research Institute

Publications

We regularly publish our findings in high impact journals indicative of the scope and quality of the research conducted by our scientists.

Recent publications

Alsalahat, I. 2022. Bilosomes as a promising nanoplatform for oral delivery of an alkaloid nutraceutical: improved pharmacokinetic profile and snowballed hypoglycemic effect in diabetic rats. Drug Delivery 29 (1), pp.2694–2704. (10.1080/10717544.2022.2110997)
Asghar, M. Y. et al., 2022. Suppression of calcium entry modulates the expression of TRβ1 and Runx2 in thyroid cancer cells, two transcription factors that regulate invasion, proliferation and thyroid-specific protein levels. Cancers 14 (23) 5838. (10.3390/cancers14235838)
Crozier, T. W. et al., 2022. Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasion. Wellcome Open Research 7 224. (10.12688/wellcomeopenres.17946.1)
Dangi, T. et al., 2022. Improved control of SARS-CoV-2 by treatment with nucleocapsid-specific monoclonal antibody. Journal of Clinical Investigation 132 (23) e162282. (10.1172/JCI162282)
Nightingale, K. et al., 2022. Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11 via recruitment of the CRL4 E3 ubiquitin ligase complex. Proceedings of the National Academy of Sciences 119 (6) e2108173119. (10.1073/pnas.2108173119)
Saud, Z. et al. 2022. Mechanically ventilated patients shed high titre live SARS-CoV2 for extended periods from both the upper and lower respiratory tract. Clinical Infectious Diseases 75 (1), pp.e82-e88. ciac170. (10.1093/cid/ciac170)
Saud, Z. et al. 2022. Anti-viral organic coatings for high touch surfaces based on smart-release, Cu2+ containing pigments. Progress in Organic Coatings 172 107135. (10.1016/j.porgcoat.2022.107135)
Saud, Z. et al. 2022. The SARS-CoV2 envelope differs from host cells, exposes pro-coagulant lipids, and is disrupted in vivo by oral rinses. Journal of Lipid Research 63 (6) 100208. (10.1016/j.jlr.2022.100208)
Scurr, M. J. et al. 2022. Magnitude of venous or capillary blood-derived SARS-CoV-2-specific T cell response determines COVID-19 immunity. Nature Communications 13 5422. (10.1038/s41467-022-32985-8)
Statkute, E. , Wang, E. and Stanton, R. 2022. An optimised CRISPR/Cas9 adenovirus vector (AdZ-CRISPR) for high throughput cloning of sgRNA, using enhanced sgRNA and Cas9 variants. Human Gene Therapy 33 (17-18), pp.990-1001. (10.1089/hum.2021.120)
Tizaoui, C. et al., 2022. Ozone for SARS-CoV-2 inactivation on surfaces and in liquid cell culture media. Journal of Hazardous Materials 428 128251. (10.1016/j.jhazmat.2022.128251)
Wang, E. C. , Fielding, C. A. and Stanton, R. J. 2022. Concerns over functional experiments, interpretation, and required controls. Journal of Clinical Investigation 132 (5) e157369. (10.1172/JCI157369)
Weiler, N. et al., 2022. Combined knockdown of RL13 and UL128 for release of cell-free infectivity from recent HCMV isolates. Journal of Virological Methods 305 114537. (10.1016/j.jviromet.2022.114537)