Based at the Behavioural Neuroscience Laboratory, School of Psychology.
My research interests fall into three main areas:
- Investigation of the role played by the hippocampus and related cortical areas in learning, memory and emotion in rodents
- The role played by synaptic plasticity mechanisms in learning and memory in rodents
- Characterisation of murine models of Alzheimer's disease and evaluation of putative therapeutic interventions
My multi-disciplinary laboratory is equipped with:
- computer-controlled operant chambers for mice and rats (including standard operant chambers, 9-hole boxes and fear conditioning chambers)
- access to three state-of-the-art watermaze testing facilities and standard maze testing environments
- two histology and immunohistochemistry facilities
- two surgical facilities (each with 4 work stations)
- in vivo field recording and unit recording facilities
- histology microscopes
- PCR and ELISA facilities
Available PhD projects
- Investigating the effects of exercise on cognitive impairments and pathology in amyloid and tau mouse models of dementia.
- Investigating the effects of tau mutations on neural network activity during memory formation and retrieval.
- Investigating the effects of antibodies against the amyloid precursor protein pathology on cognition and pathology in APP transgenic mice.
- Synaptic plasticity and the formation of configural memory in rodents.
Hippocampus, memory, emotion, Alzheimer's disease, synaptic plasticity.