Mark Good

Based at the Behavioural Neuroscience Laboratory, School of Psychology.

Research interests

My research interests fall into three main areas:

  • Investigation of the role played by the hippocampus and related cortical areas in learning, memory and emotion in rodents
  • The role played by synaptic plasticity mechanisms in learning and memory in rodents
  • Characterisation of murine models of Alzheimer's disease and evaluation of putative therapeutic interventions

Facilities

My multi-disciplinary laboratory is equipped with:

  • computer-controlled operant chambers for mice and rats (including standard operant chambers, 9-hole boxes and fear conditioning chambers)
  • access to three state-of-the-art watermaze testing facilities and standard maze testing environments
  • two histology and immunohistochemistry facilities
  • two surgical facilities (each with 4 work stations)
  • in vivo field recording and unit recording facilities
  • histology microscopes
  • PCR and ELISA facilities

 Available PhD projects

  1. Investigating the effects of exercise on cognitive impairments and pathology in amyloid and tau mouse models of dementia.
  2. Investigating the effects of tau mutations on neural network activity during memory formation and retrieval.
  3. Investigating the effects of antibodies against the amyloid precursor protein pathology on cognition and pathology in APP transgenic mice.
  4. Synaptic plasticity and the formation of configural memory in rodents.

Research keywords

Hippocampus, memory, emotion, Alzheimer's disease, synaptic plasticity.