Cardiff Regional Experimental Arthritis Treatment and Evaluation Centre (CREATE)

The CREATE Centre is part of the Rheumatology section within the School of Medicine.

We work alongside volunteer patients from Cardiff and the Vale University Health Board, to develop and test drugs to treat patients with Rheumatoid and Psoriatic arthritis. We are jointly funded by Arthritis Research UK, Health and Care Research Wales and Cardiff University.

Rheumatoid and Psoriatic Arthritis are chronic inflammatory joint conditions that result in pain, disability, joint damage and reduced quality of life. Achieving and sustaining remission has been shown to be important in arresting joint damage and improve prognosis. However, the percentage of patients who attain remission in clinical practice is estimated to be less than 30 per cent.

Aims

  • To improve the outcome of patients with rheumatoid and psoriatic arthritis by developing new treatments and diagnostic tests that will lead to more patients achieving disease remission.

If you would like to find out more about the centre or are interested in engaging with us please contact us by email.

We have established collaboration with other researchers in the area of infection and immunity to identify novel targets and develop new treatment.

Testing these novel treatments in patients with Rheumatoid and Psoriatic Arthritis will be facilitated by the South East Wales Trials Unit and the Clinical Research Facility at University Hospital of Wales.

Selected publications

Contact

Jazz Callen-Davies

Email:
callen-daviesj@cardiff.ac.uk
Telephone:
+44 (0)29 2068 7092

Academic staff

Ernest Choy

Professor Ernest Choy

Clinical Professor

Email:
choyeh@cardiff.ac.uk
Telephone:
+44 (0)29 2068 7092
Professor Robert Hills

Professor Robert Hills

Lead for Clinical Cancer Research Methodology and Portfolio Lead for Haematological Oncology

Email:
hillsrk@cardiff.ac.uk
Telephone:
+44 (0)29 2074 4647
Simon Jones

Professor Simon Jones

Dean of Research; Research Theme Lead - Infection, Inflammation & Immunity

Email:
jonessa@cardiff.ac.uk
Telephone:
+44 (0)29 2068 7325
Tim Pickles

Timothy Pickles

Research Associate - Statistics

Email:
pickleste@cardiff.ac.uk
Telephone:
+44 (0)29 2068 7259
Vincent Piguet

Professor Vincent Piguet

Director, Division of Infection and Immunity

Email:
piguetv@cardiff.ac.uk
Telephone:
+44 (0)29 2074 4721
Rebeca Playle

Dr Rebecca Playle

Senior Lecturer in Medical Statistics

Email:
playlera@cardiff.ac.uk
Telephone:
+44 29207 44821

Dr Charlotte Rawlings

Clinical Lecturer

Email:
rawlingsc@cardiff.ac.uk
Anwen Williams

Professor Anwen Williams

Director of Postgraduate Research and Deputy Dean of Research (Postgraduate)

Email:
williamsas@cardiff.ac.uk
Telephone:
+44 (0)29 2074 4733

Associated staff

Professor George Schett

University or Erlangen Nuremberg

Dr Anurag Negi

Cardiff and Vale University Health Board

Dr Sharon Jones

Cardiff and Vale University Health Board

Dr Julian Nash

Cardiff and Vale University Health Board

Dr Paul-Peter Tak

GlaxoSmithKline

Dr Jeremy Camilleri

Cardiff and Vale University Health Board

Professor Maurice Hallett

Professor, School of Medicine

Email:
hallettmb@cardiff.ac.uk
Telephone:
+44 292074 2748
Paul Morgan

Professor Paul Morgan

Director of the Systems Immunity Research Institute

Email:
morganbp@cardiff.ac.uk
Telephone:
+44 (0)29 2068 7096
Eddie Wang

Dr Eddie Wang

Reader

Email:
wangec@cardiff.ac.uk
Telephone:
+44 (0)29 2068 7035