Arthritis Research Group

Arthritis is a term used generally to describe disorders associated with the musculoskeletal system. There are over 200 different types of arthritis, which can be classified as inflammatory or non-inflammatory, acute or chronic.

Within the i3-IRG arthritis special interest group, we have investigators actively researching all aspects of the synovial joint (bone, cartilage and synovium) and how these may become compromised during disease.


  • Working together in order to improve our understanding of the mechanisms that contribute to disorders of the joint, with the view of improving the lives of people with arthritis.

Our group uses a range of experimental model systems and novel imaging techniques to reveal changes in inflammatory and degenerative synovial architecture.

We work closely with other research groups across Cardiff University.

These include:

  • Providing new model organisms for biomedical research: The tale of molluscs, mice and men.
  • Investigating the mechanism of the protective role of glutamate receptor antagonists against early onset osteoarthritis following joint destabilisation injuries.
  • Can altered cytokine signaling predict the course of inflammatory arthritis?
  • Pre-B cell colony enhancing factor (PBEF) in Rheumatoid arthritis.
  • Investigating musculoskeletal pain in arthritis using structural and functional magnetic resonance imaging (fMRI) .
  • Death receptor 3: a regulator of bone turnover and new target for therapy for osteoporosis.
  • CD59 - A novel role in bone.

Academic staff

Ernest Choy

Professor Ernest Choy

Clinical Professor

+44 (0)29 2068 7092
Simon Jones

Professor Simon Jones

Dean of Research; Research Theme Lead - Infection, Inflammation & Immunity

+44 (0)29 2068 7325
Anwen Williams

Professor Anwen Williams

Director of Postgraduate Research and Deputy Dean of Research (Postgraduate)

+44 (0)29 2074 4733
Rhian Goodfellow

Dr Rhian Goodfellow


+44 (0)29 2068 7061

Associated staff

Dr Ruth Davies

Clinical Research Fellow

Gareth Jones

Dr Gareth Jones

Arthritis Research UK Career Development Fellow

+44 (0)29 2068 7303

Dr Jason Twohig

Research Associate

+44 29206 87320

A large amount of our research has been generously funded by grants provided by:

We also receive(d) funding from: