Cancer Stem Cell Publications of Interest
Blood;
"Stem cell gene expression programs influence clinical outcome in human leukemia”. Dick J.E. et al. Nature Medicine (2011) published online 28 August 2011
Breast;
“Protein tyrosine phosphatase 1B restrains mammary alveologenesis and secretory differentiation” Milani, E. et al Development (2013) 140, 117-125. Published Online Nov 2012.
"Breast cancer stem cells: Obstacles to therapy". Smalley, M. et al. Cancer Letters (2012) published online 30 April 2012
"Suppression of Apoptosis Inhibitor c-FLIP Selectively Eliminates Breast Cancer Stem Cell Activity in Response to the Anti-cancer Agent, TRAIL" Piggott, L. et al. Breast Cancer Research (2011) 13:R88
"Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells". Lander E.S. et al. Cell (2011) 146 I4: 633-644.
Intestine/colon;
"Evidence for A Crucial Role of Paneth Cells in Mediating the Intestinal Response to Injury" Parry L, et al. Stem Cells. (2013) Jan 17. doi: 10.1002/stem.1326. [Epub ahead of print]
“Lineage Tracing Reveals Lgr5+ Stem Cell Activity in Mouse Intestinal Adenomas” Schepers, A.G. et al. Science (2012) 337 (6095):730-735
“Origin and maintenance of the intestinal cancer stem cell”. Davies EJ, Marsh V, Clarke AR. Molecular Carcinogenesis (2011) 50 (4): 254–263.
"Crypt stem cells as the cells-of-origin of intestinal cancer". Barker N. et al. Nature (2009) 457: 608-611.
"The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse". Batlle E. et al. Cell Stem Cell (2011) 8 (5): 511-524.
Lung;
"ABCG2-associated resistance to Hoechst 33342 and topotecan in a murine cell model with constitutive expression of side population characteristics". Smith PJ et al. Cytometry (2009) 75A (11): 924–933.
Pancreas
"Identification of Pancreatic Cancer Stem Cells". Simeone D.M et al. Cancer Res (2007) 67 (3): 1030-1037.
Prostate;
"Prospective Identification of Tumorigenic Prostate Cancer Stem Cells". Maitland N. J. et al. Cancer Res (2005) 65; 10946-10951.
Skin;
“Defining the mode of tumour growth by clonal analysis” Driessens, G. et al. Nature (2012) 488 527-530 (23 August 2012)
"Specific MicroRNAs Are Preferentially Expressed by Skin Stem Cells To Balance Self-Renewal and Early Lineage Commitment". Fuchs E et al. Cell Stem Cell (2011) 8(3):294-308.
"Normal stem cells in cancer prone epithelial tissues". Phesse TJ and Clarke AR. British Journal of Cancer (2009) 100: 221–227
Neural;
“A restricted cell population propagates glioblastoma growth after chemotherapy.“ Chen J. et al. Nature (2012) 488, 522–526 (23 August 2012))
"Genetic basis of tumorigenesis in NF1 malignant peripheral nerve sheath tumors". Upadhyaya M. Frontiers in Bioscience (2011) 16: 937-951
General Reviews;
“Resolving the stem-cell debate”. Gilbertson, R.J & Graham, T.A. Nature (2012) 488, 462-463 (23 August 2012)
"The increasing complexity of the cancer stem cell paradigm". Rosen JM and Jordan CT. Science. (2009) 324: 1670-1673.
