Prof John P Aggleton - BA MA Cantab DPhil Oxon
Telephone:+44(0)29 208 74563
Fax:+44(0)29 208 74858
Extension:74563
Location:School of Psychology, Cardiff University, Tower Building, Park Place, Cardiff CF10 3AT
My research concerns the ways in which different brain regions work in concert to support various aspects of learning and memory. Most of my research is focussed on episodic memory and recognition memory, including animal models of these same forms of memory. My research is multi-level as I try to integrate animal and clinical research. In order to understand brain systems I also study the nature of the anatomical connections between key structures involved in memory. Of particular interest is understanding the basis of diencephalic amnesia, and so uncovering how and why diencephalic brain structures interact with other regions in the temporal lobe and prefrontal cortex.
Selected Publications
Brown, M.W. and Aggleton, J.P. Recognition memory: what are the roles of the perirhinal cortex and hippocampus? Nature Reviews Neuroscience, 2, 51-61, 2001.
- View the Publication [380.1 Kb]
Vann, S.D. Aggleton, J.P. (2004). The mammillary bodies – two memory systems in one? Nature Reviews Neuroscience, 5, 35-44.(.pdf)
Aggleton, J.P. Brown, M.W. (2006). Interleaving brain systems for episodic and recognition memory. Trends in Cognitive Science, 10, 455-463.(.pdf)
Poirier, G.L., Amin, E. & Aggleton, J.P. (2008). Qualitatively Different Hippocampal Subfield Engagement Emerges with Mastery of a Spatial Memory Task by Rats. The Journal of Neuroscience, 28(5):1034 –1045.(.pdf)
Research Projects
2007 Wellcome Trust. PhD Programme in Integrative Neuroscience. Lead Applicant and Deputy Directory. £4,000,000 for 6 years.
2006 Wellcome Trust. Why are there parallel hippocampal – diencephalic pathways for event memory? Principal applicant. £158,395 for 3 years.
2006 Wellcome Trust. Why are there parallel hippocampal – diencephalic pathways for event memory? Co-applicant with Erichsen, Vann, O’Mara. €203,428, for 3 years
2005 BBSRC Research Equipment Initiative. Multidisciplinary core facility for microscope image analysis and three-dimensional stereology. Co-applicant with 10 others. £68,864
2005 Alzheimer’s Research Trust. Cingulate cortex hypoactivity and its contribution to dementia. Principal applicant. £35,155, 16 months
2005 BBSRC Identifying the roles of the granular and dysgranular retrosplenial cortices in spatial memory. Co-applicant with S. Vann (PI), £278,845, 3 years
2003 Renewal of MRC Programme Grant ‘ The neural substrates of familiarity and event memory’ Joint Applicant £1,782,437 with John Pearce, Malcolm Brown, Zafir Bashir, 5 years
2003 Renewal of MRC Co-operative ‘Learning, memory, and plasticity in mammalian systems’ Principal/Lead Applicant £628,663, 5 years.
2001 Higher Education Funding Council for Wales Equipment for Wellcome Trust SRIF transgenic unit. £300,000. Lead Applicant
2001 Wellcome Trust “ Cortical routes to memory: a functional comparison of the perirhinal, postrhinal and retrosplenial cortices”. Principal applicant: with Muir, 3 years, £212,000.
Strategic Research Investment Fund “ Facility for Transgenic Rodents”. Principal applicant, £1,470,300
2001 MRC Co-op Component Grant. Fornix damage and amnesia: a systematic analysis of colloid cyst cases. Principal applicant: £358, 495, 3 years.
Postgraduate Students
Emma Knott – "Studying hippocampal inputs to the mammillary bodies"
Hilary Watson - "Neuropsychology of dual-process models of recognition"