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Major Home Office research grant to support Anthrax research

12 January 2011

Prof Baillie with Prof Mitat Sahin outside Kafkas University, Turkey
Prof Baillie with Prof Mitat Sahin outside Kafkas University, Turkey

 

Prof Les Baillie of the Welsh School of Pharmacy has been awarded £267,003 by the Home Office  to evaluate the  ability  of  environmentally friendly  biocides to remediate anthrax spore contaminated environments.    

Anthrax,  a bacterial disease cause by an organism called Bacillus anthracis,  has been a scourge of man and animals since the first written history of disease. It was thought to be the cause of one of the plagues of Egypt in the time of Moses (c. 1250 BC) and accounts of its symptoms can be found in the writings of ancient scholars such as Homer (c. 1000 BC) and Galen (c. AD 200).  

  

Scanning Electron Micrograph of Bacillus anthracis spores
Scanning Electron Micrograph of Bacillus anthracis spores

More recently the bacterium played a pivotal role in the scientific flowering of the 19th century underpinning advances in medicine and immunology which  saw  naturally acquired anthrax all but eliminated from the UK. 

Unfortunately the disease still remains a major public health problem in countries such as Turkey due primarily to the ability of the bacterium to form resistant spores capable of surviving in soil for decades without losing the ability to infect susceptible individuals.  

Anthrax contaminated site in Eastern Turkey
Anthrax contaminated site in Eastern Turkey

 

For this reason the Cardiff team  in collaboration with colleagues from Industry, the UK Health Protection Agency and Kafkas University in Eastern Turkey   will  perform field trials to determine the  ability of environmentally friendly biocides and delivery platforms to remediate spore contaminated sites in manner which minimizes  collateral damage to local flora and fauna.  It is our expectation that this work will result in development of a process which could be employed  across Turkey and other endemic regions to reduce the threat posed by this organism.

 

 

Prof Les Baillie

Position:Professor of Microbiology
Image of Prof. Les Baillie
Telephone: +44 (0)29 208 75535Extension: 5535