Wednesday, 24th April 2013
Starts: 24 April 2013
Dr Mark Young
School of Biosciences, Cardiff University
The structure, function and pharmacology of P2X receptors, key modulators of pain and inflammation
I did my Ph.D. and first postdoc in the lab of Professor Mike Tanner (University of Bristol; 1997-2003), working on membrane transporter protein structure-function relationships.
I then started to work on the structure, function and pharmacology of the P2X receptor family of ATP-gated ion channels, first with Professors Annmarie Surprenant and Alan North (Universities of Sheffield and Manchester; 2003-2007), and then as a Wellcome Trust Advanced Training Fellow mentored by Professor Bob Ford (University of Manchester; 2007-2010), where I learnt to study the structure of P2X receptors using electron microscopy.
In September 2009 I was the recipient of the first Evans-Huber Fellowship at Cardiff University, a 3-year position designed to enable me to set up my own research lab, where I continue to study the 3D structure, signalling and pharmacology of mammalian P2X receptors, as well as looking to develop new expression systems for mammalian membrane proteins. At the conclusion of my Fellowship in September 2012 I was converted to Lecturer.
More information including publications can be obtained here:
Redwood, 2.60c. (New Lecture Theatre, NLT)
4pm. Refreshments from 3:50pm.
Open To: Staff and Students