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Staff profile

Mr Brian Jones 


Staff Photo of Mr Brian Jones
Position:Honorary Senior Lecturer
School:Pharmacy

Additional Information

Brian Jones graduated B Pharm from the Welsh School of Pharmacy in 1961 and completed a pre-registration year in Swansea GeneralHospital. Since then he has worked in the pharmaceutical industry apart from one year in community pharmacy. He obtained an M Pharm degree by research in 1973 for a thesis entitled hard gelatin capsule colourants, a qualitative and quantitative study. The major part of his career (29 years) was spent working for Eli Lilly & Co. Ltd, Basingstoke, UK where he was involved in providing technical support to their capsule manufacturing and filling operations and in providing a service to their capsule customers in Europe, Asia, Africa and North America. 

Since taking early retirement in 1994 he has worked as an independent consultant on hard capsules. He has been active in pharmaceutical affairs: the founder of a local branch (North Hampshire) and has served as a branch secretary, branch chairperson, regional chairperson for Wessex and 2 terms on the Industrial Pharmacists Group Committee of the RPSGB. He was made an FRPharmS in 1990 for distinction in the practice and profession of pharmacy.  He was appointed as an honorary lecturer in Drug Delivery in 1994.

Research interests                   

The manufacture and use of hard capsules, in particular hypromellose capsules and their applications as a delivery system for oral administration and for inhalation products, and in the formulation and assessment of powders for filling.

Recent Publications

Jones, B.E., Tablets & Capsules, 2010, 8(1), 1-4, “How gelatin and hypromellose capsules differ in product release during dissolution”

Jones, B.E., Basit, A.W. and Tuleu, C., Int. J. Pharm., 2012, 424, 40-43, “The disintegration behaviour of capsules in fed subjects. A comparison of hypromellose (carrageenan) capsules and standard gelatin capsules”

Jones, B.E. and Podczeck, F., Int. J. Pharm., 2012, 434, 503-506, “Letter to the editor, On performance qualification of hypromellose capsules”

Torrisi, B.M., Birchall, J.C., Jones, B.E., Díez, F. and Coulman, S.A., Int. J. Pharm., 2013, 456, 545-552, “The development of a sensitive methodology to characterise hard shell puncture by dry powder inhaler pins”

Birchall JC, Morrissey A, Jones BE, 'A comparison of the puncturing properties of gelatin and hypromellose capsules for use in dry powder inhalers'. Drug Development & Industrial Pharmacy: 2008, 34, 870-876. 

Jones BE, 'Evolution of the technology for filling two-piece hard capsules with powders'. Tablets & Capsules 2006; 4: 10-12, 14, 16-20

Jones BE, 'A new solution for formulation challenges. Business Briefings', Pharma Outsourcing 2004; January: 56-61

Jones BE, 'Quali-V®-I a new key for inhalation products'. Drug Deliv Tech 2003; 3(6): 52-57

Podczeck F, Jones BE, 'The in vitro dissolution of theophylline from different types of hard shell capsules'. Int J Pharm 2002; 28: 1163-1169

Jones BE, 'The filling of powders into two-piece hard capsules'. Int J Pharm 2001; 227: 5-26

Books:

Jones BE, Chapter 29 Hard gelatin capsules. In: Pharmaceutics, the science of dosage form design. Aulton ME ed (2007), Third edition, Churchill Livingstone, Edinburgh

Jones BE, Capsules, hard, monograph. In: Encyclopedia of pharmaceutical technology, Editors, Swarbrick, J & Boylan JC eds (2006), Third edition, Marcel Decker, New York

Podczeck F& Jones BE eds (2004), Second edition, Pharmaceutical capsules, Pharmaceutical Press, London.

Posters:

A comparison of two different types of inhalation capsules & inhaler devices on powder aerosolisation”, Saleem I., Diez F. and  Jones B.,AAPS Annual Meeting & Exposition, Chicago, Oct 14-17, 2012, Poster Number; ID-AM-12-2305

The development of a robust methodology to evaluate capsule puncture performance”, Diez F., Torrisi B.,  Birchall J.C. and Jones B.E., AAPS Annual Meeting & Exposition, San Antonio, Nov 10-14, 2013, Poster Number: R6153

“Characterising capsule puncture of different capsule types following patient actuation of a dry powder inhaler”, Jones B.E., Atrah Z., Coulman S.A.,  Birchall J.C. and  Diez F., AAPS Annual Meeting & Exposition, San Antonio, Nov 10-14, 2013, Poster Number: T3175

Influence of internal lubricant on powder aerosolization from inhalation grade hypromellose capsules (Quali-V®-I), Saleem I., Diez F. and Jones B.E., AAPS Annual Meeting & Exposition, San Antonio, Nov 2-5, 2013, Poster Number: R6177

Understanding intra- and inter-individual differences in capsule puncture following actuation of a dry powder inhaler”, Dujovny, G., Morgan, C., Diez, F., Birchall, J, Jones, B. and Coulman, S.A., AAPS Annual Meeting & Exposition, San Diego, Nov 2-5, 2014, Poster Number: T3175

Influence of temperature on capsule puncturing performance” Diez, F., Chong, R, Birchall J., Jones, B. and Coulman, S., AAPS Annual Meeting & Exposition, San Diego, Nov 2-5, 2014, Poster Number: T3176

The puncture properties and the shedding of particles of capsules in dry powder inhalers, effect of capsule type and moisture content”, Jones, B,E., Chong, Diez, F., Birchall, J.C., Chong, R., Coulman, S.A., AAPS Annual Meeting & Exposition, San Diego, Nov 2-5, 2014, Poster Number: T3178