Prof Arwyn Tomos Jones - BSc (Hons) MSc PhD Dip-Journalism
Prof Arwyn Jones was appointed as Lecturer in Molecular Cell Biology at the School of Pharmacy and Pharmaceutical Sciences, Cardiff University in 2001. He was promoted to senior Lecturer in 2007 and to Reader in Membrane Traffic and Drug Delivery in 2011. Previously he gained his PhD in protein biochemistry and crystallography at Birkbeck College, University of London. Then he undertook postdoctoral positions investigating membrane traffic on the endocytic pathway at the Physiological Laboratory, University of Liverpool and Harvard School of Public Health, Harvard University, USA.
In 2000 he was awarded a European Molecular Biology Organization fellowship to work at the European Molecular Biology Laboratory (EMBL), Heidelberg Germany and he continued at the EMBL when he was awarded an Alexander von Humboldt Foundation Scholarship.
Arwyn has a keen interest in the public understanding of science and in 2001 he was awarded a Diploma in Journalism from the University of Wales Bangor. See also Arwyn's Public Engagement with Science page.
Research projects in his lab fall under themes of cell biology and endocytosis, concentrating on linking fundamental endocytosis research to the remit of cellular delivery of macromolecular therapeutics. Ongoing projects include:
- Characterisation of endocytic pathways utilised by therapeutic macromolecules to gain access into cells
- Studying the mechanism of entry of cell penetrating peptides (CPP) and CPP-conjugates
- Designing new polymer-peptide conjugates for cellular delivery of therapeutic macromolecule
- Analysing endocytosis and degradation of receptor tyrosine kinases in breast cancer.
- Utilising subcellular fractionation for analysis of endocytosis and intracellular traffic of therapeutic macromolecules.
- Design and manufacture of microarray surfaces for multi-image analysis of biological specimens.
Organisation of scientific meetings
Together with Dr Mark Gumbleton, he is the organizer of the International Symposium Series: Cellular Delivery of Therapeutic Macromolecules (CDTM). The inaugural meeting was held in 2006 followed by the highly successful CDTM2008 and CDTM2010 that brought 200 people to Cardiff University. For CDTM updates please access http://www.cdtm.cardiff.ac.uk/
Arwyn serves on the Editorial board of the Journal of Controlled Release
Membership of scientific organizations
Member of Cardiff Institute for Tissue Engineering and Repair (CITER).
Member of the Biochemical Society.
The Public Engagement with Science
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In 2010 he lead a two year Public Engagement project sponsored by the EPSRC to highlight the multidisciplinary science involved in, and potential of, tissue engineering. This £55K Partnership for Public engagement award "Tissue Engineering for Human Healing" was obtained with Dr Bob Steadman (Medic) and Dr Pete Griffiths (Chemy) and involved setting up tissue engineering exhibits and activities at various locations and activities in Wales from July 2010 to October 2011. This was launched at the 2010 National Eisteddfod of Wales in Ebbw Vale. Included there and twelve months later at the National Eisteddfod in Wrexham were a wide range of interactive and educational activities housed at the Eisteddfod Science Pavilion throughout the week. These included a life size operations game, maggot races and a Stem Cell puzzle. The Stem Cell Puzzle will now be a regular feature at the Techniquest science centre in Cardiff Bay.