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Prof Kenneth Broadley  -  BPharm PhD DSc FBPharmacolS FRSocMed


Career Profile

Professor of Pharmacology in the School of Pharmacy and Pharmaceutical Sciences since 1997.

Visiting Fellow of the Canadian Heart Foundation, University of British Columbia, Vancouver, Canada, 1979.

Honorary Lecturer, Department of Pharmacology, University of Auckland, New Zealand, 1983.

Honorary Research Fellow, Department of Pharmacology, University of Melbourne, Australia, 1987

Director of Biology, Muscagen Ltd. (Spin-out Drug Development Company), Cardiff University, 1998-present

 

Research Interest

  • Studies on the mechanisms of lung inflammation and lung function changes in asthma, chronic obstructive pulmonary disease (COPD) and viral infection of the airways. Identification of the mechanisms of action of established and novel drugs for the treatment of airways diseases. Supported by grants from Pharmaceutical Companies.
  • Studies to evaluate the actions of dietary trace amines such as tyramine and β-phenylethylamine found in cheese, yoghourt and wines, and related amphetamine-like drugs. Particular interest is focused on cardiovascular actions of amphetamines such as ecstasy, methamphetamine and cathinone, the active constituent of khat leaves, chewed for their euphoric effects. These agents have been implicated in cardiovascular complications associated with their overuse and abuse. Supported by the Wellcome Trust and British Heart Foundation
  • Studies on the mechanisms involved in cardiac protection from ischaemic damage of the heart caused by block of a coronary artery (myocardial infarction, heart attack). The roles of adenosine and catecholamines via β-adrenoceptors in cardioprotection. Supported by the British Heart Foundation.

 

Other Research Activities

Editor-in-Chief (1982-2006) now Deputy Editor of Autonomic & Autacoid Pharmacology, Blackwell Scientific Publications.

 

Editorial Boards 

 

Textbook

  • Broadley K J - Sole Author Autonomic Pharmacology Taylor & Francis (1996) pp. 1-612

 

Series Editor

  • Respiratory Pharmacology, Current Opinion in Pharmacology Editorial Belvisi, M. & Broadley, K.J. Don’t forget the nose and pulmonary circulation! (2005) 5, 211-213.
  • Member Committee of Heads of Pharmacology (CHOPS)

 

Postgraduate External Examiner

  • DSc: University of Wales (x1), University of London (x1) and University of Bradford (x1)
  • PhD: Universities of Aston, Cambridge (x2), Hertfordshire (x2), Leicester, Liverpool, London (UCL, Imperial, King’s)(x9), Manchester, Surrey, Sheffield, Open University (x3) and Melbourne (x2) and Monash (x2), Australia

 

Student Prizes of supervised projects

  • Peter Penson won the UK SET (Science, Engineering and Technology) Student of the Year Award for the Best Pharmacology student The award, made by GlaxoSmithKline and judged by the British Pharmacological Society, was for his work, Nifedipine – a pharmacological re-evaluation of its vasodilator activity.
  • Toby Toward was awarded the Servier Best Poster award by a postgraduate at the British Pharmacological Society Meeting in 2001 (Toward, T.J., Maillard, J-Y., Boult, J.E. & Broadley,K.J. (2002). Airway function, hyperreactivity, cell influx and nitric oxide, in parainfluenza-3 infection: effect of dexamethasone and rolipram. Br. J. Pharmacol. 135, 73P)