Prof Gary F. Baxter - B Pharm, MSc, PhD, DSc, MRPharmS, FBPharmacolS, FIBiol, FESC, FAHA,
Selected recent publications (2003-present)
Z Giricz, A Gorbe, J Pipis, D S Burley, P Ferdinandy & G F Baxter. Hyperlipidaemia induced by a high-cholesterol diet leads to the deterioration of guanosine-3',5'-cyclic monophosphate/protein kinase G-dependent cardioprotection. Br J Pharmacol; in press DOI : 10.1111/j.1476-5381.2009.00424
S A Hamid, M Totzeck, C Drexhage, I Thompson, R C Fowkes, T Rassaf & G F Baxter. Nitric oxide/cGMP signalling mediates the cardioprotective action of adrenomedullin in reperfused myocardium. Basic Res Cardiol; in press DOI:10.1007/s00395-009-0058-7
Burley DS, Baxter GF. Pharmacological targets revealed by myocardial postconditioning. Curr Opin Pharmacol 2009; 177-188
G F Baxter & D S Burley. Reperfusion and calculated RISKs: pharmacological postconditioning of human myocardium (commentary). Br J Pharmacol 2008; 153: 1-3
M J Kleinz & G F Baxter. Apelin reduces myocardial reperfusion injury independently of PI3K/Akt and P70S6 kinase activation. Regulatory Peptides 2008; 146: 271-277
P Ferdinandy, R Schulz & G F Baxter. Interaction of cardiovascular risk factors with ischemia/reperfusion injury, preconditioning and postconditioning. Pharmacol Reviews 2007; 59: 418-458
Z Ebrahim, D M Yellon & G F Baxter. Attenuated cardioprotective response to bradykinin, but not classical ischemic preconditioning, in DOCA-salt hypertensive left ventricular hypertrophy. Pharmacol Res 2007; 55: 42-48
S A Hamid, H S F Bower & G F Baxter. Rho-kinase activation plays a major role as a mediator of irreversible injury in reperfused myocardium. Am J Physiol Heart Circ Physiol 2007; 292: H2598-H2606
Z Ebrahim, D M Yellon & G F Baxter. Ischemic preconditioning is lost in aging hypertensive heart: independent effects of aging and longstanding hypertension. Experimental Gerontology 2007; 42: 807-814
D Burley, S A Hamid & G F Baxter. Cardioprotective actions of peptide hormones in myocardial ischemia. Heart Failure Reviews 2007; 12: 279-291
D Burley, P Ferdinandy & G F Baxter. Cyclic GMP and protein kinase G in ischaemia-reperfusion: opportunities and obstacles in survival signalling. Br J Pharmacol 2007; 152: 855-869
D Burley & G F Baxter. B-type natriuretic peptide at early reperfusion limits infarct size in the isolated heart. Basic Res Cardiol 2007; 102: 529-41
D Roy, J Quiles, D Gaze, P Collinson, J C Kaski & G F Baxter. Role of reactive oxygen species on formation of the novel diagnostic marker, ischemia modified albumin. Heart 2006; 92: 113-114
D Johansen, K Ytrehus & G F Baxter. Exogenous hydrogen sulfide (H2S) protects against regional myocardial ischemia-reperfusion injury: evidence for a role of KATP channels. Basic Res Cardiol 2006; 101: 53-60
S A Hamid & G F Baxter. A critical cytoprotective role of endogenous adrenomedullin in acute myocardial infarction (rapid communication). J Mol Cell Cardiol 2006; 41: 360-363
S A Hamid & G F Baxter. Adrenomedullin: regulator of myocardial survival, function and architecture in infarction. Pharmacol Ther 2005; 105: 95-112
S A Hamid & Baxter GF. Adrenomedullin limits reperfusion injury in experimental myocardial infarction. Basic Res Cardiol 2005, 100: 387-396
M A C Fauchon, T J Pell, G F Baxter, D S Latchman, M F Hubank & L V Mayne. Representational difference analysis of cDNA identifies novel genes expressed following preconditioning of the heart. Exp Mol Med 2005; 37: 311-22.
S P D’Souza, M Davies, G F Baxter. Autocrine and paracrine actions of natriuretic peptides in the heart. Pharmacol Ther 2004; 101: 113-129
G F Baxter. The natriuretic peptides: an introduction. Basic Res Cardiol 2004; 99: 71-75
G F Baxter. Natriuretic peptides in myocardial ischaemia. Basic Res Cardiol 2004; 99: 90-93
Y Rautureau & G F Baxter. Acute actions of natriuretic peptides in coronary vasculature and ischaemic myocardium. Curr Pharm Des 2004; 10; 2477-2482
S P D’Souza, D M Yellon, C Martin, R Schulz, G Heusch, A Onody, P Ferdinandy & G F Baxter. B-type natriuretic peptide (BNP) limits infarct size in isolated heart via KATP channel opening. Am J Physiol 2003; 284: H1592-H1600
S P D’Souza & G F Baxter. B-type natriuretic peptide: a good omen in myocardial ischaemia? Heart 2003; 89: 707-709
A Kis, D M Yellon & G F Baxter. Second window of protection following myocardial preconditioning: an essential role of PI3 Kinase and p70S6 kinase. J Mol Cell Cardiol 2003; 35: 1063-1071