Professor Mike Bruford FLSW
Co-director Sustainable Places Research Institute
- +44 (0)29 2087 4312
- +44 (0)29 2087 4116
I am a molecular ecologist interested in studying the demographic and evolutionary processes in endangered species.
My group focuses on understanding the determinants of genome diversity and structure over a variety of spatio-temporal scales, from examining the movements of individuals within territories to studying the impacts of social structure on genetic diversity in fragmented ecosystems to studying species throughout their range with continent-wide dispersal patterns.
We orient our projects towards an understanding of the basic processes governing the evolution of endangered species and place substantial emphasis on the provision of data and recommendations to management authorities for action and policy development.
We study a combination of elusive wild species (e.g. orang-utans in Borneo) and model species such as livestock breeds whose demographic history is often well understood and where genome resources are abundant.
We use methods such as forensic DNA profiling through to whole genome sequencing and we integrate these data with landscape analysis (GIS) and genealogical modeling in an effort to provide comprehensive information for biodiversity management and conservation.
I did my PhD at the University of Leicester on the development of DNA fingerprinting techniques in birds and genome mapping in chickens using minisatellite DNA markers between 1986 and 1990. Between 1990 and 1999 I worked as a postdoctoral research associate, research fellow and then Head of Conservation Genetics at the Institute of Zoology, Zoological Society of London. I joined Cardiff University in 1999, and I am currently Division Leader for Organisms and Environment.
I currently serve on the editorial boards of Conservation Genetics Resources, Integrative Zoology and Endangered Species Research. I have previously served on the editorial review board for Molecular Ecology and was a founding editor for the journal Animal Conservation. I also currently serve on the Steering Committee for the Wales Biodiversity Partnership, the Academy of Finland's Ecology Grants Committee and the External Advisory Board for the University of Lisbon's Centre for Environmental Biology.
I was awarded the Zoological Society of London's Scientific Medal in 2003, was elected a Fellow of the Learned Society of Wales in 2010 and I am currently a Royal Society Wolfson Research Merit Award holder (2012-2016).
Heredity is a high quality general genetics journal and in the 2011 ISI rankings is 27/157 journals in Genetics and Heredity with an impact factor of 4.597.
My research focuses on the application of molecular genetics and genomics to the conservation of endangered species and livestock breeds. My groups seeks to understand how genetic diversity evolves in small populations, the role that local adaptation plays and its consequence for conservation biology and management. Research in this field is necessarily collaborative in nature and our projects are based in countries including China (Institute of Zoology, Chinese Academy of Sciences), Gabon (Wildlife Conservation Society and University of New Orleans), Peru (CONOPA and San Marcos University), Abu Dhabi (Environment Agency of Abu Dhabi and International Wildlife Consultants, Carmarthen, Wales) and Malaysia (Danau Girang Field Centre, HUTAN, Universiti Malaysia Sabah, Sabah Wildlife Department).
We have particularly focused on using molecular data in elusive species to assist direct conservation management questions, particularly in great apes and other conservation flagship species. Implementation of conservation management plans for such species has strong implications for the viability of other species inhabiting the same ecosystems and such 'flagship' organisms can provide umbrella protection for biodiversity as a whole, yet the biology of long-lived and enigmatic organisms such as the giant panda and Bornean orang-utan is surprisingly poorly understood. Our recent research on these organisms was recognized in Discover magazine's top 100 scientific breakthroughs for 2006, where two of our studies (Goossens et al 2006; Zhan et al 2006) were recognized.
As part of out policy and management activities, we coordinate the EU Framework 7 Support Action Project ConGRESS which aims to provide genetic information in a user-friendly web portal to policy-makers and biodiversity managers across the European Union. The project involves 13 partners across the EU (see map below) and end-users from 19 countries, whose input is guiding the development of the portal during 2012 and 2013. Responsible scientist: Dr Isa-Rita Russo.
Our work is becoming more focused on genome-level analysis, as whole genome-based population and evolutionary genetic analysis becomes feasible due to recent technical advances in sequencing and bioinformatics. We are participating in the Nextgen project (http://nextgen.epfl.ch/), coordinated by Prof Pierre Taberlet, Universite Joseph Fourier, Grenoble and our research focuses on genome-wide analysis of local adaptation in Moroccan sheep, systematically sampled across an extreme environmental gradient (temperature, rainfall) north and south of the Atlas mountains. Responsible scientist: Dr Pablo Orozco-TerWengel, also visiting scientist from University del Bio Bio, Chile - Dr Juan-Carlos Marin and Sardinian government PhD student Mario Barbato.
Falcon Genome project
While domestic livestock species have well-established genome resources available for studies of local adaptation, most wild species lack such resources and genome sequences must be first developed de novo. We are collaborating with International Wildlife Consultants (www.falcons.co.uk) and the Environment Agency Abu Dhabi to establish these resources for two iconic and heavily traded falcons, the peregrine and saker. We are collaborating with BGI-Shenzhen (http://en.genomics.cn/navigation/index.action) to sequence the genomes of these two species, and provide the baseline resources for studies of local adaptation across the vast geographic ranges that both species occupy. Responsible scientist: Dr Xiangjiang Zhan.
Note: if required please use username 'nopriv' and password 'bruford' to access the above downloads.
Our work is currently supported by:
- The Royal Society
- The European Commission
- The Environment Agency Abu Dhabi
- The Leverhulme Trust
Examples within the School and University include:
- Prof Bill Symondson: dietary diversity and population structure of cave-dwelling bats in the Kinabatangan catchment (PhD student Azniza Mahyudin, Malaysian government)
- Dr Peter Kille and Prof A John Morgan: native and invasive earthworm population dynamics, local adaptation and heavy metal soils (NERC, Leverhulme Trust, PhD student Pierfrancesco Sechi, Sardinian government)
- Prof Steve Ormerod and Dr T Hefin Jones: genetic diversity, ecosystem resilience and climate change (PhD student Hannah Burton, Cardiff University President's Scholarship)
- Dr Benoit Goossens: conservation genetics of proboscis monkeys and Bornean banteng (PhD students Senthilvel Nathan and Penny Gardner, Danau Girang Field Centre)
- Dr Isabelle Durance, Prof Susan Baker (School of Social Sciences), Prof Ian Hall (School of Earth and Ocean Sciences): resilience in coupled natural-social systems (Cardiff University Sustainable Places Research Institute)
- Prof Susan Baker (School of Social Sciences): Socio-Ecological Analysis of Natural Resource Governance: The Management of Scale, Interplay and Fit in Kinabatangan Wildlife Sanctuary, Malaysia (ESRC/NERC PhD student Richard Bloor)
Other external examples include:
- Prof Tamas Szekely (University of Bath): Landscape genetics of Madagascan wetland birds (Leverhulme Trust Postdoctoral scientist Eddie Brede)
- Professor Fuwen Wei (Chinese Academy of Sciences, Institute of Zoology): Population genetics and phylogeography of keystone species in the greater Shangri-la ecoregion. (Royal Society, Chinese NSFC Postdoctoral Researcher Xiangjiang Zhan).
- Dr Jane Wheeler, Professor Raul Rosadio (CONOPA and the University of San Marcos, Lima, Peru): Conservation of genetic resources in South American camelids. (Darwin Initiative, Cardiff University)
- Drs Jinliang Wang, John Ewen, Noelle Kumpfel, Linda Penfold, John Hart (Zoological Society of London, White Oaks Conservation Centre, Bonobo in Congo): Range-wide genetic analysis of the okapi (NERC CASE PhD student Dave Stanton)
- Drs Yoshan Moodley and Paul O'Donoghue (Konrad Lorenz Institute for Ethology, University of Chester): Population and conservation genetics of the black rhinoceros (International Rhino Foundation postdoctoral researcher Isa Rita Russo)
- Prof Margarida Santos Reis (Centre for Environmental Biology, University of Lisbon): Landscape and population genetics of Portuguese carnivores (Portuguese Foundation for Science and Technology)
- Dr Edward Brede (Leverhulme Trust-funded Postdoctoral Researcher)
- Dr Pablo Orozco-TerWengel (EC-funded Postdoctoral Researcher)
- Dr Juan-Carlos Marin (visiting from University of Bio Bio, Chile)
- Dr Isa-Rita Russo (South African NRF Fellow)
- Dr Xiangjiang Zhan (Environment Agency Abu Dhabi-funded Postdoctoral Researcher)
- Mario Barbato (Sardinian Government)
- Mafalda Basto (FCT, Portugal, co-supervised with Prof Margarida Santos-Reis, University of Lisbon)
- Hannah Burton (Cardiff University, President's Scholarship, co-supervised with Prof Steve Ormerod and Dr T Hefin Jones)
- Mafalda Costa (FCT, Portugal, co-supervised with Prof Margarida Santos-Reis, University of Lisbon)
- Robert Donnelly (Leverhulme Trust, University of Glamorgan, co-supervised with Prof A John Morgan)
- Azniza Mahyudin (Malaysian Government, cosupervised with Prof Bill Symondson)
- Niall McCann (BBSRC CASE with Operation Wallacea, co-supervised with Dr Phil Wheeler, University of Hull)
- Tania Minhos (FCT, Portugal, co-supervised with Dr Catarina Casanova, New University of Lisbon)
- Rui Sa (FCT, Portugal, co-supervised with Dr Claudia Sousa, New University of Lisbon)
- Pierfrancesco Sechi (Sardinian Government, co-supervised with Dr Peter Kille)
- Joana Silva (FCT, Portugal, co-supervised with Dr Catarina Casanova, New University of Lisbon)
- Dave Stanton (NERC CASE with the Zoological Society of London, co-supervised with Drs Jinliang Wang and John Ewen)