![Mahmoud Akhtar](https://profiles-cardiff.imgix.net/attachments/1462?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Overview
- Combining synthetic chemistry and biology approaches to generate novel drugs.
- Synthetic biology to generate novel unnatural terpenoids through protein and metabolic engineering.
- Intracellular Biphotonic Nanoswitches: programmed control of molecular pathways with light.
- Mechanistic studies of enzymatic hydrogen tunnelling.
Links
Further Information: Professor Allemann's research page
Publication
2004
- Miller, D. J., Bashir-Uddin Surfraz, M., Akhtar, M., Gani, D. and Allemann, R. K. 2004. Removal of the phosphate group in mechanism-based inhibitors of inositol monophosphatase leads to unusual inhibitory activity. Organic & Biomolecular Chemistry 2(5), pp. 671-688. (10.1039/b312808c)
- Bashir-Uddin Surfraz, M., Akhtar, M. and Allemann, R. K. 2004. Bis-benzyl protected 6-amino cyclitols are poisonous to Pd/C catalysed hydrogenolysis of benzyl ethers. Tetrahedron Letters 45(6), pp. 1223-1226. (10.1016/j.tetlet.2003.11.130)
Articles
- Miller, D. J., Bashir-Uddin Surfraz, M., Akhtar, M., Gani, D. and Allemann, R. K. 2004. Removal of the phosphate group in mechanism-based inhibitors of inositol monophosphatase leads to unusual inhibitory activity. Organic & Biomolecular Chemistry 2(5), pp. 671-688. (10.1039/b312808c)
- Bashir-Uddin Surfraz, M., Akhtar, M. and Allemann, R. K. 2004. Bis-benzyl protected 6-amino cyclitols are poisonous to Pd/C catalysed hydrogenolysis of benzyl ethers. Tetrahedron Letters 45(6), pp. 1223-1226. (10.1016/j.tetlet.2003.11.130)
Biography
PhD University of Southampton (1988, D. Gani, stereochemistry and mechanistic studies of amino acid metabolising enzymes). Post-doctoral Research Fellow, University of Southampton (1988-90, D. Gani, study of the chemistry of tobacco-specific nitrosamine catabolism; stereochemical and mechanistic studies of PLP dependent decarboxylases). Post-doctoral Research Fellow, University of St. Andrews (1990-93, D. Gani, stereochemical and mechanistic Studies of b-methylaspartase; design and use microreactors for use in combinatorial chemistry and solid-phase synthesis). Senior Scientific Officer, University of St. Andrews (1993-98; organic and biological chemistry). Project Officer and Teaching Instructor, University of Birmingham (1998-2005, organic and biological chemistry). Appointed Senior Scientific Officer, Cardiff, in 2005, responsible for the day-to-day management of Professor R. K. Allemann's research group. In 2008, took on the additional role of Research and Fiscal Manager.
Links
Further Information: Professor Allemann's research page
Committees and reviewing
PhD University of Southampton (1988, D. Gani, stereochemistry and mechanistic studies of amino acid metabolising enzymes). Post-doctoral Research Fellow, University of Southampton (1988-90, D. Gani, study of the chemistry of tobacco-specific nitrosamine catabolism; stereochemical and mechanistic studies of PLP dependent decarboxylases). Post-doctoral Research Fellow, University of St. Andrews (1990-93, D. Gani, stereochemical and mechanistic Studies of b-methylaspartase; design and use microreactors for use in combinatorial chemistry and solid-phase synthesis). Senior Scientific Officer, University of St. Andrews (1993-98; organic and biological chemistry). Project Officer and Teaching Instructor, University of Birmingham (1998-2005, organic and biological chemistry). Appointed Senior Scientific Officer, Cardiff, in 2005, responsible for the day-to-day management of Professor R. K. Allemann's research group. In 2008, took on the additional role of Research and Fiscal Manager.