Dr Eleri Owen-Jones
(she/her)
BSc (Hons), PhD
Research Associate
- Owen-JonesCE@cardiff.ac.uk
- Neuadd Meirionnydd, Room 708B, University Hospital of Wales, Heath Park, Cardiff, CF14 4YS
- Welsh speaking
- Available for postgraduate supervision
Overview
I am a trial manager/research associate at the Research Trials Centre. I have clinical trial experience in a wide range of disciplines. I am currently managing the Sono-breech study - evaluating the use of hand-held ultrasound devices to detect breech pregnancies; the Solutions trial - evaluating a solution focused therapy to children and young people presenting at a police custody suite; Stand Together - evaluating an anti-bullying programme called KiVa in schools; TAPERS trial - Treating Anxiety to PrevEnt Reslapse in pSychosis: a feasibility trial, funded by Research for Patient and Public Benefit (RfPPB) Wales; and the TTTS study - ultrasound-guided high intensity focusing ultrasound for the treatment of early pregnancy Twin-Twin Transfusion Syndrome funded by the MRC.
Previous trials I have managed include the following: PRINCESS trial - Probiotics to Reduce Infections iN CarE home reSidentS funded by NIHR EME; Building Blocks - Evaluating the Family Nurse Partnership program at Englnd; CREAM - Children with eczema, stuttering; A randomized, double-blind, placebo-controlled study of RAD001 (Everolimus) in the treatment of neurocognitive problems in tubular sclerosis.
Publication
2023
- Gillespie, D. et al. 2023. Gut microbiology of UK care home residents: cross-sectional analysis from a randomised controlled trial. Clinical Microbiology and Infection 29(11), pp. 1437-1442. (10.1016/j.cmi.2023.08.001)
2022
- Robling, M. et al. 2022. A nurse-led home-visitation programme for first-time mothers in reducing maltreatment and improving child health and development (BB:2-6): longer-term outcomes from a randomised cohort using data-linkage. BMJ Open 12(2), article number: e049960. (10.1136/bmjopen-2021-049960)
2021
- Castro-Herrera, V. M. et al. 2021. Combination of the probiotics Lacticaseibacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis, BB-12 has limited effect on biomarkers of immunity and inflammation in older people resident in care homes: results from the Probiotics to Reduce Infections iN CarE home reSidentS Randomized, Controlled Trial. Frontiers in Immunology 12, article number: 643321. (10.3389/fimmu.2021.643321)
- M.Castro-Herrera, V. et al. 2021. Relationship between age, frailty, length of care home residence and biomarkers of immunity and inflammation in older care residents in the UK. Frontiers in Aging 2, article number: 599084. (10.3389/fragi.2021.599084)
2020
- Butler, C. C. et al. 2020. Effect of probiotic use on antibiotic administration among care home residents: a randomized clinical trial. Journal of the American Medical Association 324(1), pp. 47 - 56. (10.1001/jama.2020.8556)
2019
- Owen-Jones, E. et al. 2019. Protocol for a double-blind placebo-controlled trial to evaluate the efficacy of probiotics in reducing antibiotics for infection in care home residents: the Probiotics to Reduce Infections iN CarE home reSidentS (PRINCESS) trial. BMJ Open 9(6), article number: e027513. (10.1136/bmjopen-2018-027513)
2017
- Lugg-Widger, F. et al. 2017. Assessing the medium-term impact of a home-visiting programme on child maltreatment in England: protocol for a routine data linkage study. BMJ Open 7, article number: e015728. (10.1136/bmjopen-2016-015728)
2016
- Randell, E. et al. 2016. The use of everolimus in the treatment of neurocognitive problems in tuberous sclerosis (TRON): study protocol for a randomised controlled trial. Trials 17, article number: 398. (10.1186/s13063-016-1446-6)
- Robling, M. et al. 2016. Effectiveness of a nurse-led intensive home-visitation programme for first-time teenage mothers (Building Blocks): a pragmatic randomised controlled trial. Lancet 387(10014), pp. 146-155. (10.1016/S0140-6736(15)00392-X)
2013
- Owen-Jones, C. E. et al. 2013. The effectiveness and cost-effectiveness of the Family Nurse Partnership home visiting programme for first time teenage mothers in England: a protocol for the Building Blocks randomised controlled trial. BMC Pediatrics 13(114) (10.1186/1471-2431-13-114)
2010
- Kelly, M. J. et al. 2010. Delays in response and triage times reduce patient satisfaction and enablement after using out-of-hours services. Family Practice 27(6), pp. 652-663. (10.1093/fampra/cmq057)
- Kinnersley, P. R. et al. 2010. The need to improve the interface between in-hours and out-of-hours GP care, and between out-of-hours care and self-care. Family Practice 27(6), pp. 664-672. (10.1093/fampra/cmq056)
2004
- Owen-Jones, C. E. 2004. Stem cells in human oral epithelium. PhD Thesis, Cardiff University.
2002
- Baines, P. et al. 2002. Increased circulating normal and BCR-ABL+Ve progenitor numbers in Philadelphia chromosome-positive acute myeloid leukaemia. Leukemia Research 26(11), pp. 997-1005. (10.1016/S0145-2126(02)00049-8)
1999
- Austin, S. J., Robinson, L. G., Owen-Jones, C. E., Mills, K. I. and Burnett, A. 1999. Quantitation of AML1-ETO fusion transcripts in t(8;21) positive AML using real-time light cycler PCR [Abstract]. British Journal of Haematology 105, pp. 76.
- Robinson, L. G., Owen-Jones, C. E., Austin, S., Mills, K. I. and Burnett, A. K. 1999. Relationship between PCR status following chemotherapy and outcome in t(8;21) positive acute myeloid leukaemia [Abstract]. British Journal of Haematology 105(Sup.1), pp. 67.
- Owen-Jones, C., Robinson, L. G., Austin, S., Bailey-Wood, R., Agar, A., Mills, K. and Burnett, A. K. 1999. Absence of leukaemic cell contamination of bone marrow (BM) and peripheral blood stem cell (PBSC) harvests as detected by PCR in good risk Acute Myeloid Leukaemia. British Journal of Haematology 105(Supp 1), pp. 56-56.
- Robinson, L. G. et al. 1999. Altered gene expression in 32D cells expressing the AML1A gene or AML1-ETO fusion gene. British Journal of Haematology 105(Supp1), pp. 103-103.
1998
- Austin, S. J., Robinson, L. G., Owen-Jones, C. E., Mills, K. I. and Burnett, A. K. 1998. Real-time PCR (lightcycler technology) for quantitation of AML1-ETO fusion transcripts in t(8;21) positive AML. Blood 92(10), pp. 75A-75A.
- Robinson, L. G., Austin, S. J., Owen-Jones, C. E., Al-Sabah, A., Bailey-Wood, R., Mills, K. I. and Burnett, A. K. 1998. Prognostic value of IgH rearrangement detection in peripheral blood stem cell (PBSC) harvests of patients with Multiple Myeloma undergoing PBSC transplantation [Abstract]. British Journal of Haematology 102(1), pp. 292-293. (10.1111/j.1365-2141.1998.tb08997.x)
- Robinson, L. G., Austin, S. J., Owen-Jones, C. E., Langabeer, S. E., Linch, D. C., Mills, K. I. and Burnett, A. 1998. Multiplex PCR for the detection of prognostically important gene rearrangements in acute myeloid leukaemia [Abstract]. British Journal of Haematology 101(S), pp. 21.
1997
- Robinson, L., Owen-Jones, C. E., Bowen, D., Langabeer, S., Linch, D., Mills, K. I. and Burnett, A. K. 1997. Multiplex PCR for the detection of prognostically important chromosomal abnormalities in acute myeloid leukaemia [Abstract]. Blood 90(10), pp. 276.
Articles
- Gillespie, D. et al. 2023. Gut microbiology of UK care home residents: cross-sectional analysis from a randomised controlled trial. Clinical Microbiology and Infection 29(11), pp. 1437-1442. (10.1016/j.cmi.2023.08.001)
- Robling, M. et al. 2022. A nurse-led home-visitation programme for first-time mothers in reducing maltreatment and improving child health and development (BB:2-6): longer-term outcomes from a randomised cohort using data-linkage. BMJ Open 12(2), article number: e049960. (10.1136/bmjopen-2021-049960)
- Castro-Herrera, V. M. et al. 2021. Combination of the probiotics Lacticaseibacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis, BB-12 has limited effect on biomarkers of immunity and inflammation in older people resident in care homes: results from the Probiotics to Reduce Infections iN CarE home reSidentS Randomized, Controlled Trial. Frontiers in Immunology 12, article number: 643321. (10.3389/fimmu.2021.643321)
- M.Castro-Herrera, V. et al. 2021. Relationship between age, frailty, length of care home residence and biomarkers of immunity and inflammation in older care residents in the UK. Frontiers in Aging 2, article number: 599084. (10.3389/fragi.2021.599084)
- Butler, C. C. et al. 2020. Effect of probiotic use on antibiotic administration among care home residents: a randomized clinical trial. Journal of the American Medical Association 324(1), pp. 47 - 56. (10.1001/jama.2020.8556)
- Owen-Jones, E. et al. 2019. Protocol for a double-blind placebo-controlled trial to evaluate the efficacy of probiotics in reducing antibiotics for infection in care home residents: the Probiotics to Reduce Infections iN CarE home reSidentS (PRINCESS) trial. BMJ Open 9(6), article number: e027513. (10.1136/bmjopen-2018-027513)
- Lugg-Widger, F. et al. 2017. Assessing the medium-term impact of a home-visiting programme on child maltreatment in England: protocol for a routine data linkage study. BMJ Open 7, article number: e015728. (10.1136/bmjopen-2016-015728)
- Randell, E. et al. 2016. The use of everolimus in the treatment of neurocognitive problems in tuberous sclerosis (TRON): study protocol for a randomised controlled trial. Trials 17, article number: 398. (10.1186/s13063-016-1446-6)
- Robling, M. et al. 2016. Effectiveness of a nurse-led intensive home-visitation programme for first-time teenage mothers (Building Blocks): a pragmatic randomised controlled trial. Lancet 387(10014), pp. 146-155. (10.1016/S0140-6736(15)00392-X)
- Owen-Jones, C. E. et al. 2013. The effectiveness and cost-effectiveness of the Family Nurse Partnership home visiting programme for first time teenage mothers in England: a protocol for the Building Blocks randomised controlled trial. BMC Pediatrics 13(114) (10.1186/1471-2431-13-114)
- Kelly, M. J. et al. 2010. Delays in response and triage times reduce patient satisfaction and enablement after using out-of-hours services. Family Practice 27(6), pp. 652-663. (10.1093/fampra/cmq057)
- Kinnersley, P. R. et al. 2010. The need to improve the interface between in-hours and out-of-hours GP care, and between out-of-hours care and self-care. Family Practice 27(6), pp. 664-672. (10.1093/fampra/cmq056)
- Baines, P. et al. 2002. Increased circulating normal and BCR-ABL+Ve progenitor numbers in Philadelphia chromosome-positive acute myeloid leukaemia. Leukemia Research 26(11), pp. 997-1005. (10.1016/S0145-2126(02)00049-8)
- Austin, S. J., Robinson, L. G., Owen-Jones, C. E., Mills, K. I. and Burnett, A. 1999. Quantitation of AML1-ETO fusion transcripts in t(8;21) positive AML using real-time light cycler PCR [Abstract]. British Journal of Haematology 105, pp. 76.
- Robinson, L. G., Owen-Jones, C. E., Austin, S., Mills, K. I. and Burnett, A. K. 1999. Relationship between PCR status following chemotherapy and outcome in t(8;21) positive acute myeloid leukaemia [Abstract]. British Journal of Haematology 105(Sup.1), pp. 67.
- Owen-Jones, C., Robinson, L. G., Austin, S., Bailey-Wood, R., Agar, A., Mills, K. and Burnett, A. K. 1999. Absence of leukaemic cell contamination of bone marrow (BM) and peripheral blood stem cell (PBSC) harvests as detected by PCR in good risk Acute Myeloid Leukaemia. British Journal of Haematology 105(Supp 1), pp. 56-56.
- Robinson, L. G. et al. 1999. Altered gene expression in 32D cells expressing the AML1A gene or AML1-ETO fusion gene. British Journal of Haematology 105(Supp1), pp. 103-103.
- Austin, S. J., Robinson, L. G., Owen-Jones, C. E., Mills, K. I. and Burnett, A. K. 1998. Real-time PCR (lightcycler technology) for quantitation of AML1-ETO fusion transcripts in t(8;21) positive AML. Blood 92(10), pp. 75A-75A.
- Robinson, L. G., Austin, S. J., Owen-Jones, C. E., Al-Sabah, A., Bailey-Wood, R., Mills, K. I. and Burnett, A. K. 1998. Prognostic value of IgH rearrangement detection in peripheral blood stem cell (PBSC) harvests of patients with Multiple Myeloma undergoing PBSC transplantation [Abstract]. British Journal of Haematology 102(1), pp. 292-293. (10.1111/j.1365-2141.1998.tb08997.x)
- Robinson, L. G., Austin, S. J., Owen-Jones, C. E., Langabeer, S. E., Linch, D. C., Mills, K. I. and Burnett, A. 1998. Multiplex PCR for the detection of prognostically important gene rearrangements in acute myeloid leukaemia [Abstract]. British Journal of Haematology 101(S), pp. 21.
- Robinson, L., Owen-Jones, C. E., Bowen, D., Langabeer, S., Linch, D., Mills, K. I. and Burnett, A. K. 1997. Multiplex PCR for the detection of prognostically important chromosomal abnormalities in acute myeloid leukaemia [Abstract]. Blood 90(10), pp. 276.
Thesis
- Owen-Jones, C. E. 2004. Stem cells in human oral epithelium. PhD Thesis, Cardiff University.
Biography
Education and qualifications:
1999 - 2004: University of Wales College of Medicine, Department of Adult Dental Health - Ph.D. titled Stem cells in human oral epithelium (funded by the MRC), awarded February 2004. The position of stem cells or stem cell zones were investigated in oral epithelium in vivo, and in vitro using cell culture and in a skin-like model (organotypic culture), using a variety of techniques.
May 2000: University of Wales College of Medicine, Diploma in Biomedical Methods (Pass) - A diverse range of laboratory methods and IT subjects were covered.
1992 - 1995: University of Wales Aberystwyth, B.Sc. (Hons.) in Genetics and Biochemistry (Class 2.1) - Studied agriculture, biochemistry, biological organisms and processes, biotechnology, genetics, medical biochemistry, microbial diversity and microbiology.
Career overview:
July 2007 – to date: Centre for Trials Research - Trial Manager.
May 2007 to July 2007: Oxford Pharmaceutical Sciences - Medical Writer.
Oct 2004 to March 2007: Marix Drug Development Limited, Llantrisant - Project Manager.
Apr 1996 to Sept 1999: Department of Haematology, University of Wales College of Medicine, Cardiff - Research Technician.